JP2011111408A - External preparation for skin - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an external preparation for skin having alopecia preventing action; hair growing action; hair nourishing action; ameliorating action on pruritus or dandruff; fungicidal or inhibitory action on athlete's foot causative fungi; inhibitory action on (per)oxidation of scalp sebum; and bactericidal or inhibitory action on skin indigenous bacteria. <P>SOLUTION: As a result of intensive studies made on the external preparation for the skin using the crude drugs derived from the nature, and having excellent safety, it is characterized by including Plectranthus fluticosus belonging to family Labiatae or the Plectranthus fluticosus and further one or two or more kinds of crude drugs therein. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

The present invention relates to an external preparation for skin characterized by using Bordochley belonging to the family Lamiaceae, and in particular, a hair loss preventing action, a hair growth action, a hair nourishing action, an itching or dandruff improving action, a sterilization of athlete's foot causative bacteria or The present invention relates to a skin external preparation that exhibits an inhibitory action, a (per) oxidation inhibitory action of scalp sebum, a bactericidal or inhibitory action of skin resident bacteria.

Conventionally, many skin external preparations that act on skin diseases such as eczema, atopy, athlete's foot, and body odor caused by skin resident bacteria are known.
These external preparations for skin are intended to improve symptoms by suppressing itching and killing or suppressing bacteria.

Specifically, the topical skin preparation for the scalp improves the itch and dandruff symptoms and promotes blood circulation of the scalp, which in turn prevents hair loss and promotes hair growth and hair growth. The topical skin preparation such as an agent suppresses body odor by sterilizing or suppressing skin resident bacteria.

These skin external preparations are filled with a variety of products including pharmaceuticals, quasi-drugs, and cosmetics. In recent years, many products containing various drugs have been sold.
For example, drugs used for external preparations for skin include nutrients such as vitamins and amino acids, as well as vasodilators, anti-inflammatory agents, female hormone agents, skin function enhancers, etc. The ingredients and drugs are blended into the skin external preparation.

However, many of these components and medicines themselves are expensive and inevitably increase the price of the product, so that it has been difficult to use them continuously for a long period of time.
Moreover, since there are concerns about side effects such as causing irritation to the skin when an excessive amount of the drug is blended, an amount sufficient to obtain a sufficient effect may not be blended.

In recent years, there has been an increase in consumers seeking safe and secure products, and natural ingredients have been attracting attention and favored, and there are many skin external preparations that use active ingredients extracted from natural plants. It has been developed.

For example, Patent Document 1 discloses a hair growth or hair growth agent containing an extract of moon peach, and Patent Document 2 discloses a hair growth agent mainly composed of a medicinal component of aloe.

JP 2000-355525 A JP 11-35431 A

However, even though the conventional skin external preparations containing these naturally-derived components are said to have effective effects, those that exhibit satisfactory effective effects have not yet been obtained.
Therefore, as a result of intensive research on a topical skin preparation using a natural herb with excellent safety, the inventor of the present application has found this problem by including one or more herbs in Bold Chile or Bold Chile. The inventors have found that this can be solved, and have completed the present invention.

In order to solve the above problems, the present invention takes the following technical means.

The invention according to claim 1 is a skin external preparation characterized by using a perennial bordotile (scientific name: Plectranthus fluticosus) belonging to the family Lamiaceae as a raw material.

Bold Chile is also called “Indio leaf” in Brazil, and contains bitter glycosides called plectrantin and enmain.

The invention according to the present invention is characterized in that bordotille is used as a raw material, and uses any organ regardless of an organ (eg, root, stem, leaf, flower, seed). .
In addition, you may use squeezed juice or an extract.

The skin external preparation of the present invention can be applied to the skin regardless of pharmaceuticals, quasi-drugs, and cosmetics to prevent hair loss, hair growth, hair nourishing, itching or dandruff, It has an inhibitory action, a (per) oxidation inhibitory action of scalp sebum, and a bactericidal or inhibitory action of skin resident bacteria, and can improve symptoms.

Further, the external preparation for skin of the present invention is not limited to a specific site, and is effective for the skin of the whole body.For example, in the scalp, there is an effect of improving the blood circulation state and preventing hair loss, In the itching of the skin, it is possible to reduce or improve the symptoms by suppressing the itching.
Furthermore, the effect of healing athlete's foot and suppressing body odor can be obtained by the sterilizing or inhibiting action of athlete's foot cause bacteria and skin resident bacteria.

The shape of the external preparation for skin of the present invention may be any of liquid, solid, mist, foam, etc. For example, external preparations such as lotion, emulsion, serum, cream, pack, tonic, tic, aerosol, etc. Examples include cosmetics.

The skin external preparation of the present invention is a component used in general external preparations and cosmetics, for example, surfactants, alcohols, fats, thickeners, preservatives, antioxidants, perfumes, pigments / colorants, An ultraviolet ray absorbing / blocking agent, a whitening agent, a chelating agent, a pH adjusting agent, water and the like can also be blended.

The invention according to claim 2 is an external preparation for skin, characterized in that it contains an extract of bordotille.
The extraction method may be any method, and an extract is obtained by a known extraction method.

The invention according to this claim is characterized by containing an extract of Bold Chile, and is intended for all organs (for example, roots, stems, leaves, flowers, seeds), and extracts of specific organs. It is not limited to.

The invention according to claim 3 is an external preparation for skin characterized in that Bord Chile is soaked in distilled liquor and the soaked liquid is a main component.

Examples of the distilled liquor in the present invention including the invention according to this claim include shochu, awamori, whiskey, brandy, vodka, tequila, etc., but any distilled liquor may be used.
However, distilled liquor with less odor is more desirable as an external preparation for skin, and white liquor is suitable.

The method of immersing in distilled liquor in the present invention including the invention according to the present invention may be any state as long as it is immersed in distilled liquor. It may be pickled directly without any pretreatment.

The external preparation for skin mainly composed of a distilled liquor dipping solution in the present invention including the invention according to the present claim can use all of the dipping solution, for example, only the supernatant of the dipping solution may be used. Alternatively, a liquid which is precipitated and becomes turbid may be used, and further, the immersion liquid may be diluted and used.

The invention according to claim 4 is an external preparation for skin characterized by using, as a raw material, one or more selected from aloe, seeker, moon peach, and ginger in addition to Bold Chile.

In addition to Bold Chile, one or more selected from Aloe, Sikhwasa, Moon Peach and Ginger are used as raw materials to contain the active ingredients of herbal medicines in order to obtain further effective effects of external preparations for skin.

The aloe, seeker, moon peach, and ginger in the present invention including the claimed invention can use any organ, regardless of the organ (eg, root, stem, leaf, flower, seed), Juice or an extract may be used.

The invention according to claim 5 is a topical skin preparation characterized by containing one or more extracts selected from aloe, schikuwaser, moon peach, and ginger in addition to Bold Chile.

In addition to the extract of Bold Chile, in order to obtain the effectiveness of further external preparations for skin, one or more extracts selected from aloe, shikwasa, moon peach and ginger are included in order to contain an active ingredient of herbal medicine. It is a thing.

The invention according to claim 6 is that, in addition to Bold Chile, further, one or more selected from aloe, seeker, moon peach and ginger are soaked in distilled liquor, and the soaking liquid is the main component. It is a skin external preparation characterized.

In addition to Bold Chile, in order to obtain further effective effects of skin external preparations, one or more selected from Aloe, Sikhwasa, Moon Peach and Ginger are soaked in distilled liquor to contain the active ingredients of herbal medicines, and soaked The liquid is the main component.

The invention according to claim 7 is characterized in that the skin external preparation according to any one of claims 1 to 6 is a hair loss preventing action, a hair growth action, a hair nourishing action, an itching or dandruff improving action, It is a skin external preparation characterized by having at least one action among a bactericidal or inhibitory action, a (per) oxidation inhibitory action of scalp oil, and a bactericidal or inhibitory action of skin resident bacteria.

The external preparation for skin according to this claim is not limited to a specific part, regardless of whether it is a pharmaceutical, a quasi-drug, or a cosmetic. For example, in the scalp, blood circulation It has the effect of improving the condition and preventing hair loss. In the case of itching of the skin, the symptoms can be alleviated and improved by suppressing itching, and the athlete's foot is cured by the sterilization or suppression action of athlete's foot cause bacteria and skin resident bacteria. The effect which suppresses body odor can be acquired.

The present invention has the following effects.

1) It has an excellent itch / dandruff improving effect and (per) oxidation inhibiting effect of sebum.

2) It has an excellent hair loss preventing action, hair growth action, and hair restoration action.

3) The effect of preventing hair loss can be obtained by improving pruritus, dandruff and lipid (per) oxidation of the scalp and activating hair papilla cells.

4) Effects such as promoting hair growth and hair growth can be expected.

5) It has an excellent sterilizing / suppressing action against athlete's foot causing bacteria, and can be expected to alleviate and cure athlete's foot symptoms.

6) It has excellent bactericidal and inhibitory effects on skin resident bacteria and can be expected to suppress or alleviate body odor.

<Example 1>
A skin external preparation is produced by obtaining a soaking solution in which Bold Chile is soaked in distilled liquor.
Distilled liquor uses white liquor with low odor.
Bold chile uses leaves and stems.
First, 1 kg of Bold Chilean stems with leaves attached are placed in a container, and about 54 L of white liquor (35 degrees) is added.
Bord chile may be put after separating the leaves and stems.
The container is sealed with a lid.
Leave in a cool and dark place at room temperature for about 3 months.
Meanwhile, stir about once every few weeks.
This soaking liquid becomes the skin external preparation of the present invention.

<Example 2>
Bold chillet and other ingredients are soaked in distilled liquor to obtain a skin external preparation.
Distilled liquor uses white liquor with low odor.
Bold chile uses leaves and stems.
Other ingredients include moon peach, seeker, aloe and ginger.
Moon peaches use leaves and stems, Sikhwasa uses fruits, and aloe uses jelly-like mesophyll and ginger rhizomes.
In a container, put 1 kg of Bold Chile, 70 leaves of moon peach, 3 kg of moon peach stalk, 6 kg of squeaker fruit, 3 kg of aloe mesophyll, and 250 g of ginger rhizome, and then add about 54 L of white liquor (35 degrees).
Each material is used as it is if it is of a size that can be accommodated in a container. For example, moon peach leaves and stems may be cut to about 5 cm each.
Bord chile may be put after separating the leaves and stems.
Although aloe can use the outer skin of a leaf, since the pickled solution becomes blackish brown, it is not used in this embodiment, and the outer skin is peeled off and only the mesophyll portion of jelly is used.
Ginger is peeled and then cut into rings.
For the seeker, the fruit may be used as it is, or may be used after being cut into small pieces.
After all the ingredients are in place, cover the container and seal.
Leave in a cool and dark place at room temperature for about 3 months.
Meanwhile, stir about once every few weeks.
This soaking liquid becomes the skin external preparation of the present invention.

The test results are as follows.

<Test result 1>
・ Test subjects: Mr. A (50 years old male)
Test method: The present skin external preparation of Examples 1 and 2 was applied to the affected area suffering from atopic dermatitis in the morning and evening.

-As a result of Example 1, after the start of the test, itching of the skin began to subside gradually immediately after application of the skin external preparation of Example 1.
Thereafter, while applying the skin external preparation of Example 1, itching was considerably relieved.

As a result of Example 2, immediately after the start of the test, immediately after applying the external preparation for skin of Example 2, the itching of the skin gradually began to subside.
Thereafter, itching was considerably relieved while applying the skin external preparation of Example 2.
Moreover, the skin of the applied part was moistened, and the dry state was alleviated.
Furthermore, the fragrance of the external preparation for skin application of the present application brought a relaxed mental state.

<Test result 2>
・ Test subjects: Mr. B (62 years old male)
Test Method: The skin external preparation of the present application of Examples 1 and 2 was applied to parts that feel body odor due to sweating in the morning, especially to the sides and neck.

-As a result of Example 1, the day when the skin external preparation of Example 1 was applied after the start of the test did not feel the body odor due to the resident skin bacterium after sweating even in the evening.
The body odor was reliably suppressed on the day when the skin external preparation of Example 1 was applied, compared to the day when it was not applied.

-As a result of Example 2, after the start of the test, on the day when the external preparation for skin of Example 2 was applied, the body odor due to the skin resident bacteria was not felt after sweating even in the evening.
The body odor was reliably suppressed on the day when the external preparation for skin of Example 2 was applied, compared to the day when it was not applied.
Moreover, the fragrance of the external preparation for skin of Example 2 not only suppressed body odor, but also made it feel refreshed.

<Test result 3>
・ Test subjects: Mr. C (a 45-year-old man)
Test method: The skin external preparation of Examples 1 and 2 was applied to the affected area suffering athlete's foot symptoms in the morning and evening.

-As a result of Example 1, immediately after applying the skin external preparation of Example 1, the itching of the affected area began to subside gradually after the start of the test.
Thereafter, while applying the external preparation for skin of Example 1, almost no itching was felt.

-As a result of Example 2, immediately after applying the skin external preparation of Example 2, the itching of the affected area began to subside gradually after the start of the test.
Thereafter, while applying the skin external preparation of Example 2, itching was hardly felt.
In addition, the horny erosion of the affected area gradually healed.
Furthermore, the fragrance of the external preparation for skin of Example 2 alleviated foot odor.

<Test result 4>
・ Test subjects: Mr. D (53-year-old male)
Test method: The present skin external preparation of Examples 1 and 2 was applied to the scalp in the morning and evening.

Results of Example 1 One week after the start of the test, the secretion of sebum in the scalp to which the external preparation for skin of Example 1 was applied was suppressed, and the excessively secreted state was alleviated.
Later, blood circulation in the scalp was promoted, and dandruff and itching were alleviated.
One month after the start of the test, the amount of hair loss decreased, the hair became thicker, and it felt stiff.
Later, it was discovered that the hair was growing locally.

Results of Example 2 One week after the start of the test, secretion of sebum in the scalp to which the external preparation for skin of Example 2 was applied was suppressed, and the excessively secreted state was alleviated.
Later, blood circulation in the scalp was promoted, and dandruff and itching were alleviated.
One month after the start of the test, the amount of hair loss decreased, the hair became thicker, and it felt stiff.
Later, it was discovered that the hair was growing locally.

Mr. E (53-year-old male), Mr. F (48-year-old male), Mr. G (66-year-old male) and Mr. H (59-year-old male) have the same tests as Mr. A, Mr. B, Mr. C and Mr. D, respectively. As a result, almost the same result was obtained.

Claims (7)

An external preparation for skin characterized by using Bold Chile belonging to Lamiaceae. An external preparation for skin containing an extract of Bold Chile belonging to Lamiaceae. A topical skin preparation characterized by comprising as a main component a soaking solution obtained by soaking Bord Chile belonging to Lamiaceae in distilled liquor. An external preparation for skin, characterized by using one or more selected from aloe, shikwasa, moon peach, ginger and Bordochiret belonging to the family Lamiaceae. A skin external preparation characterized by containing one or more selected from aloe, shikwasa, moon peach and ginger and an extract of Bordochrey belonging to Lamiaceae. A skin external preparation characterized by comprising as a main component a dipping solution obtained by dipping one or more selected from aloe, shikwasa, moon peach, ginger and bordechiret belonging to Lamiaceae in distilled liquor. The above-mentioned external preparation for skin is a hair loss preventing action, hair growth action, hair nourishing action, itching or dandruff improving action, sterilizing or inhibiting action of athlete's foot causative bacteria, (per) oxidation inhibiting action of scalp oil, sterilization of skin resident bacteria or The skin external preparation according to any one of claims 1 to 6, wherein the skin external preparation has at least one of its inhibitory effects.