JP2011068592A - Plant disease control composition and method for controlling plant disease - Google Patents

Abstract

【選択図】なしThe present invention provides a plant disease control composition having high plant disease control activity and a method capable of effectively controlling plant diseases.
A compound represented by the formula (I) and at least one compound selected from the group consisting of benomyl, thiophanate methyl, carbendazim, iminoctadine arbesylate, iminotazine acetate, boscalid, fenhexamide, and chlorothalonil A plant disease control composition containing as an active ingredient.

[Selection figure] None

Description

  The present invention relates to a plant disease control composition and a plant disease control method.

  Conventionally, various plant disease control agents have been developed to control plant diseases (see, for example, Patent Document 1), but there is always a demand for plant disease control agents with higher activity.

JP 2000-226374 A

  An object of this invention is to provide the plant disease control composition which has high plant disease control activity, and the method which can control a plant disease effectively.

で示される化合物と、ベノミル、チオファネートメチル、カルベンダジム、イミノクタジンアルベシル酸塩、イミノクタジン酢酸塩、ボスカリド、フェンヘキサミド、クロロタロニルからなる群より選ばれる少なくとも１種の化合物とを有効成分として含有する植物病害防除組成物。
〔２〕 〔１〕の式（Ｉ）で表される化合物と、ベノミル、チオファネートメチル、カルベンダジム、イミノクタジンアルベシル酸塩、イミノクタジン酢酸塩、ボスカリド、フェンヘキサミド、クロロタロニルからなる群より選ばれる少なくとも１種の化合物との重量比が、1：０．２５〜１：１である〔１〕に記載の植物病害防除組成物。
〔３〕 〔１〕の式（Ｉ）で表される化合物と、ベノミル、チオファネートメチル、カルベンダジム、イミノクタジンアルベシル酸塩、イミノクタジン酢酸塩、ボスカリド、フェンヘキサミド、クロロタロニルからなる群より選ばれる少なくとも１種の化合物との有効量を植物または植物を栽培する土壌に施用する植物病害防除方法。
〔４〕 植物病害を防除するための、〔１〕の式（Ｉ）で表される化合物と、ベノミル、チオファネートメチル、カルベンダジム、イミノクタジンアルベシル酸塩、イミノクタジン酢酸塩、ボスカリド、フェンヘキサミド、クロロタロニルからなる群より選ばれる少なくとも１種の化合物との組み合わせの使用。 Under such circumstances, the present inventors diligently studied, and as a result, consisted of a compound represented by the following formula (1), benomyl, thiophanate methyl, carbendazim, iminotadine albecylate, iminotadine acetate, boscalid, fenhexamide, chlorothalonil It has been found that an excellent plant disease control effect can be obtained by using in combination with at least one compound selected from the group, and the present invention has been achieved.
That is, the present invention has the following configuration.
[1] Formula (I)

A plant disease comprising as an active ingredient a compound represented by the formula: and at least one compound selected from the group consisting of benomyl, thiophanate methyl, carbendazim, iminotadine albecylate, iminocazine acetate, boscalid, fenhexamide, and chlorothalonil Control composition.
[2] At least one selected from the group consisting of the compound represented by the formula (I) of [1] and benomyl, thiophanate methyl, carbendazim, iminoctagine albecylate, iminoctadine acetate, boscalid, phenhexamide, and chlorothalonil. The plant disease control composition according to [1], wherein the weight ratio to the seed compound is 1: 0.25 to 1: 1.
[3] At least one selected from the group consisting of a compound represented by the formula (I) of [1] and benomyl, thiophanate methyl, carbendazim, iminoctadine albecylate, iminoctadine acetate, boscalid, phenhexamide, and chlorothalonil. A method for controlling plant diseases, which comprises applying an effective amount with a seed compound to a plant or soil for cultivating the plant.
[4] A compound represented by the formula (I) of [1] for controlling plant diseases, and benomyl, thiophanate methyl, carbendazim, iminoctadine albecylate, iminoctazine acetate, boscalid, phenhexamide, chlorothalonil Use of a combination with at least one compound selected from the group consisting of

  The plant disease control composition according to the present invention exhibits high plant disease control activity. Moreover, according to the plant disease control method which concerns on this invention, a plant disease can be controlled effectively.

で示される化合物（以下、「化合物Ｉ」と称する場合がある。）と、ベノミル、チオファネートメチル、カルベンダジム、イミノクタジンアルベシル酸塩、イミノクタジン酢酸塩、ボスカリド、フェンヘキサミド、クロロタロニルからなる群より選ばれる少なくとも１種の化合物（以下、「化合物（Ａ）」と称する場合がある。）とを有効成分として含有する。 The plant disease control composition according to the present invention (hereinafter sometimes referred to as “the composition of the present invention”) has the formula (I)

Selected from the group consisting of benomyl, thiophanate methyl, carbendazim, iminoctadine arbesylate, iminoctadine acetate, boscalid, fenhexamide, and chlorothalonil. It contains at least one compound (hereinafter sometimes referred to as “compound (A)”) as an active ingredient.

  Compound I is a known compound and can be synthesized by, for example, the method described in JP-A-2000-226374.

Benomyl is described in, for example, “The Pesticide Manual Fourteenth edition” published by British Crop Protection Council (BCPC), p. 75-77, with 1- (butylcarbamoyl) benzimidazole-2. -Methyl 1- (butylcarbamoyl) benzimidazol-2-ylcarbamate.
Thiophanate methyl can be obtained, for example, by adding dimethyl-4,4 ′-(ortho-) to p.1036-1037 of “The Pesticide Manual Fourteenth edition” published by British Crop Protection Council (BCPC). Phenylene) bis (3-thioallophanate) (Dimethyl 4,4 '-(o-phenylene) bis (3-thioallophanate).
For example, carbendazim is described in p.144-146 of “The Pesticide Manual Fourteenth edition” published by British Crop Protection Council (BCPC) on methyl benzimidazol-2-ylcarbamate. (Methyl benzimidazol-2-ylcarbamate).
For example, iminoctadine albecyl salt is a 1,1′-iminodi acid in p. 600-602 published by “The Pesticide Manual Fourteenth edition”, British Crop Protection Council (BCPC). (Octamethylene) diguanidinium tris (alkylbenzenesulfonate) (1,1'-iminodi (octamethylene) diguanidinium tris (alkylbenzenesulfonate).
For example, iminotadine acetate can be obtained by using 1,1′-iminodi (octa) in p.600-602 of “The Pesticide Manual Fourteenth edition” published by British Crop Protection Council (BCPC). Methylene) diguanidinium triacetate (1,1'-iminodi (octamethylene) diguanidinium triacetate).
Boscalid is described, for example, in 2-chloro-N- (4′-chlorobiphenyl) on p.110 of “The Pesticide Manual Fourteenth edition” published by British Crop Protection Council (BCPC). -2-yl) nicotinamide (2-chloro-N- (4′-chlorobiphenyl-2-yl) nicotinamide).
Fenhexamide is described in, for example, p.436-437 of “The Pesticide Manual Fourteenth edition”, British Crop Protection Council (BCPC), 2 ′, 3′-dichloro- 4'-hydroxy-1-methylcyclohexanecarboxanilide (2 ', 3'-dichloro-4'-hydroxy-1-methylcyclohexanecarboxanilide).
Chlorothalonyl is described as Tetrachloroisophthalonitrile in, for example, “The Pesticide Manual Fourteenth edition” published by British Crop Protection Council (BCPC) p.180-182. Has been.

  In the composition of the present invention, the ratio of compound (A) to compound I is a weight ratio (= compound (A): compound I), usually 0.125: 1 to 20: 1, preferably 0.25: 1. -10: 1, more preferably 0.25: 1 to 1: 1.

The composition of the present invention may be a mixture of the compound (A) and the compound I, but the compound (A), the compound I and an inert carrier are mixed, and if necessary, a surfactant or other preparation. Liquid preparations and solids such as wettable powder, granular wettable powder, flowable powder, granules, dry flowable liquid, emulsion, aqueous liquid, oil, smoke, aerosol, microcapsule, etc. A preparation such as a preparation may be used.
In the composition of the present invention, the total amount of compound (A) and compound I is usually 0.1 to 99% by weight, preferably 0.2 to 90% by weight.

  Examples of the solid carrier include clays (for example, kaolin, diatomaceous earth, synthetic hydrous silicon oxide, fusami clay, bentonite, acidic clay), talc, and other inorganic minerals (for example, sericite, quartz powder, sulfur powder, activated carbon, Examples thereof include fine powders or granular materials such as calcium carbonate and hydrated silica. Examples of the liquid carrier include water, alcohols (eg, methanol, ethanol), ketones (eg, acetone, methyl ethyl ketone), aromatic hydrocarbons (eg, benzene, toluene, xylene, ethylbenzene, methylnaphthalene), fat Group hydrocarbons (eg, n-hexane, cyclohexanone, kerosene), esters (eg, ethyl acetate, butyl acetate), nitriles (eg, acetonitrile, isobutyl nitrile), ethers (eg, dioxane, diisopropyl ether), Acid amides (for example, dimethylformamide, dimethylacetamide), halogenated hydrocarbons (for example, dichloroethane, trichloroethylene, carbon tetrachloride) and the like can be mentioned.

  Examples of the surfactant include alkyl sulfates, alkyl sulfonates, alkyl aryl sulfonates, alkyl aryl ethers and polyoxyethylene compounds thereof, polyoxyethylene glycol ethers, polyhydric alcohol esters, sugar alcohol derivatives. Etc.

  Examples of other formulation adjuvants include, for example, fixing agents, dispersants, stabilizers, etc., specifically casein, gelatin, polysaccharides (eg, starch, arabic gum, cellulose derivatives, alginic acid), lignin derivatives, bentonite, saccharides, Synthetic water-soluble polymers (eg, polyvinyl alcohol, polyvinyl pyrrolidone, polyacrylic acids), PAP (isopropyl acid phosphate), BHT (2,6-di-tert-butyl-4-methylphenol), BHA (2-tert -Mixtures of butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol), vegetable oils, mineral oils, fatty acids or esters thereof.

  The composition of the present invention is prepared, for example, by separately formulating the compound (A) and the compound I by the above-described method, etc., further diluting with water as necessary, and mixing each formulation or diluent. You can also

  The plant disease control composition according to the present invention is effective, for example, for the following plant diseases. However, it is not limited to these.

Rice diseases: rice blast (Magnaporthe grisea), sesame leaf blight (Cochliobolus miyabeanus), blight (Rhizoctonia solani), idiot seedling (Gibberella fujikuroi);
Wheat diseases: powdery mildew (Erysiphe graminis), red mold (Fusarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale), rust (Puccinia striiformis, P. graminis, P. recondite, P. hordei) , Snow rot (Typhula sp., Micronectriella nivalis), Bare scab (Ustilago tritici, U. nuda), Tunat scab (Tilletia caries), Eye spot (Pseudocercosporella herpotrichoides), Cloud scab (Rhynchosporium secalis), Leaf blight Disease (Septoria tritici), blight (Leptosphaeria nodorum), and net blotch (Pyrenophora teres Drechsler);
Citrus diseases: black spot (Diaporthe citri), common scab (Elsinoe fawcetti), fruit rot (Penicillium digitatum, P. italicum);
Apple diseases: Monilinia mali, rot (Valsa ceratosperma), powdery mildew (Podosphaera leucotricha), spotted leaf (Alternaria alternate apple pathotype), black star (Venturia inaequalis), anthracnose (Colletotrichum acutatum) , Plague (Phytophtora cactorum);
Pear diseases: black spot disease (Venturia nashicola, V. pirina), black spot disease (Alternaria alternate Japanese pear pathotype), red star disease (Gymnosporangium haraeanum), plague (Phytophtora cactorum);
Peach diseases: Monilinia fructicola, Black scab (Cladosporium carpophilum), Phomopsis sp. (Phomopsis sp.);
Grape diseases: black rot (Elsinoe ampelina), late rot (Glomerella cingulata), powdery mildew (Uncinula necator), rust (Phakopsora ampelopsidis), black lot (Guignardia bidwellii), downy mildew (Plasmopara viticola) ;
Oyster diseases: Anthracnose (Gloeosporium kaki), Deciduous leaf disease (Cercospora kaki, Mycosphaerella nawae);
Diseases of cucurbits: Anthracnose (Colletotrichum lagenarium), powdery mildew (Sphaerotheca fuliginea), vine blight (Mycosphaerella melonis), vine split (Fusarium oxysporum), downy mildew (Pseudoperonospora cubensis), plague (Phytophthora sp. ), Seedling blight (Pythium sp.);
Tomato diseases: ring rot (Alternaria solani), leaf mold (Cladosporium fulvum), plague (Phytophthora infestans);
Eggplant diseases: brown spot disease (Phomopsis vexans), powdery mildew (Erysiphe cichoracearum);
Diseases of cruciferous vegetables: black spot disease (Alternaria japonica), white spot disease (Cercosporella brassicae), clubroot (Plasmodiophora brassicae), downy mildew (Peronospora parasitica);
Leek disease: rust (Puccinia allii);
Diseases of soybean: purple spot disease (Cercospora kikuchii), black spot disease (Elsinoe glycines), black spot disease (Diaporthe phaseolorum var. Sojae), rust disease (Phakopsora pachyrhizi), stem rot (Phytophthora sojae);
Kidney Disease: Anthracnose (Colletotrichum lindemthianum);
Peanut disease: black astringency (Cercospora personata), brown spot (Cercospora arachidicola), white silkworm (Sclerotium rolfsii);
Pea disease: powdery mildew (Erysiphe pisi);
Potato diseases: Summer plague (Alternaria solani), plague (Phytophthora infestans), powdery scab (Spongospora subterranean f. Sp. Subterranea);
Strawberry disease: powdery mildew (Sphaerotheca humuli);
Tea diseases: net blast (Exobasidium reticulatum), white spot (Elsinoe leucospila), ring spot (Pestalotiopsis sp.), Anthracnose (Colletotrichum theae-sinensis);
Tobacco diseases: Alternaria longipes, powdery mildew (Erysiphe cichoracearum), anthracnose (Colletotrichum tabacum), downy mildew (Peronospora tabacina), plague (Phytophthora nicotianae);
Sugar beet diseases: brown spot (Cercospora beticola), leaf rot (Thanatephorus cucumeris), root rot (Thanatephorus cucumeris), black root (Aphanidermatum cochlioides);
Rose diseases: black spot disease (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa);
Chrysanthemum diseases: brown spot (Septoria chrysanthemi-indici), white rust (Puccinia horiana);
Diseases of various plants: diseases caused by Pythium spp. (Pythium aphanidermatum, Pythium debarianum, Pythium graminicola, Pythium irregulare, Pythium ultimum), gray mold disease (Botrytis cinerea), mycorrhizal disease (Sclerotinia sclerotiorum);
Radish disease: Black spot disease (Alternaria brassicicola);
Diseases of Shiva: Dollar spot disease (Sclerotinia homeocarpa), Brown patch disease and Large patch disease (Rhizoctonia solani);
Banana disease: Sigatoka disease (Mycosphaerella fijiensis, Mycosphaerella musicola, Pseudocercospora musae).

  The composition of the present invention is used simultaneously with or without mixing with other fungicides, insecticides, acaricides, nematicides, herbicides, plant growth regulators, fertilizers, soil conditioners, and the like. You can also. As the above-mentioned fungicides, insecticides, acaricides, nematicides, herbicides, plant growth regulators, fertilizers and soil conditioners, known ones can be used.

The plant disease control method according to the present invention (hereinafter sometimes referred to as “the present invention control method”) applies an effective amount of the compound (A) and the compound I to a plant, soil for cultivating the plant, or the like. To do. Examples of plants to be applied include plant stems and leaves, plant seeds, plant bulbs, and the like. Here, the bulb means a bulb, a bulb, a rhizome, a tuber, a tuberous root, and a root support body.
When applied to plants, soil for cultivating plants, etc., the compound (A) and the compound I may be applied separately at the same time, but usually, from the viewpoint of simplicity during application, the control composition of the present invention. Apply as.
Specific examples of the control method of the present invention include treatment of plants on foliage such as foliage spraying, treatment of plants such as soil treatment on cultivated land, and treatment of seeds such as seed disinfection.

Specific examples of the treatment of the foliage of the plant in the control method of the present invention include a treatment method applied to the surface of the plant such as foliage spraying and trunk spraying. Examples of the treatment method for directly absorbing the plant before transplantation include a method of immersing the whole plant or the root. Moreover, what was formulated with a solid carrier such as mineral powder may be attached to the root.
Examples of the soil treatment method in the control method of the present invention include, for example, spraying on the soil, mixing with the soil, and chemical irrigation to the soil (chemical irrigation, soil injection, chemical drip). Crop, near planting hole, near crop line, whole area of plantation area, plant land edge, between stocks, under trunk, trunk trunk, cultivation soil, seedling box, seedling tray, nursery, etc. Examples include the sowing time, immediately after sowing, the seedling growing season, before planting, at the time of planting, and the growing season after planting. Moreover, in the said soil treatment, an active ingredient may be processed simultaneously to a plant, and solid fertilizers, such as a paste fertilizer containing an active ingredient, may be applied to soil. Moreover, you may mix with an irrigation liquid, for example, the injection | pouring to irrigation equipments (irrigation tube, irrigation pipe, a sprinkler, etc.), the mixing to a streak water solution, mixing to a hydroponics etc. are mentioned. In addition, the irrigation liquid and the active ingredient can be mixed in advance, and can be treated using an appropriate irrigation method such as the above irrigation method or other watering or watering.
Examples of the treatment for seeds in the control method of the present invention include a method of treating the plant disease control composition of the present invention on seeds, bulbs and the like of plants to be protected from plant diseases, specifically, for example, , A spray treatment in which the suspension of the plant disease control composition of the present invention is atomized and sprayed on the seed surface or bulb surface, a small amount in the wettable powder, emulsion or flowable agent of the plant disease control composition of the present invention A coating treatment in which water is added to the seed or bulb as it is, an immersion treatment in which the seed is immersed in the solution of the plant disease control composition of the present invention for a certain time, a film coating treatment, and a pellet coating treatment.

The application amount of Compound (A) and Compound I varies depending on the type of plant to be treated, the type and degree of occurrence of plant diseases to be controlled, formulation form, application time, application method, application location, weather conditions, etc. In the case of treating the foliage of the plant or treating the soil, the total amount of the compound (A) and the compound I (hereinafter referred to as “the amount of the active ingredient”) is usually 1 to 1000 m ² . 500 g, preferably 2 to 200 g. In the treatment for seeds, the amount of the active ingredient is usually 0.001 to 10 g, preferably 0.01 to 1 g, per 1 kg of seeds.
Emulsions, wettable powders, suspensions, etc. are usually applied by diluting with water and spraying. In this case, the concentration of the active ingredient is usually 0.0005 to 2% by weight, preferably 0.005 to 1% by weight. Powders, granules, etc. are usually processed without dilution.

In the method for controlling the present invention, when the compound (A) and the compound I are applied separately, the respective compounds may be applied, for example, by the method described above, and the application order of both compounds is not particularly limited. The application method of each compound may be the same or different. However, the application interval between the two is preferably short, and is preferably within one day.
The ratio of the compound (A) and the compound I applied separately is a weight ratio (= compound (A): compound I), usually 0.125: 1 to 20: 1, preferably 0.25: 1 to 10. : 1, more preferably 0.25: 1 to 1: 1.

When the control of plant diseases is carried out with a bactericide, a treatment method may be used in which two or more types of bactericides with different working mechanisms are used and treated at appropriate intervals. Even in the case of using Compound I, such a treatment method is effective.
For example, when Compound I is used for controlling grape gray mold, Compound I is treated at the time of grape flowering, and Boscalid, Fenhexamide, Pyrimethanyl (N- (4,6-dimethylpyrimidin-2) -yl) aniline), cyprodinil (4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine), fludioxonyl (4- (2,2-difluoro-1,3-benzodioxol-4-yl) pyrrole-3- carbonitrile), when one compound selected from a mixture of cyprodinil and fludioxonil is treated, a high control effect is obtained. Even if the compound to be treated at the flowering time and the compound to be treated at the time of discoloration of the grape fruit are exchanged, the same high control effect can be obtained.

  For example, when Compound I is used for the control of legume gray mold and mycorrhizal disease, Compound I, Boscalid, Procymidone (N- (3,5-dichlorophenyl)- 1,2-dimethylcyclopropane-1,2-dicarboximide), mepanipyrim (N- (4-methyl-6-prop-1-ynylpyrimidin-2-yl) aniline), thiophanate methyl (dimethyl 4,4 '-(o-phenylene) One compound selected from a mixture of bis (3-thioallophanate) and mepanipyrim and a mixture of thiophanate methyl and dietofencarb (isopropyl 3,4-diethoxycarbanilate) (hereinafter referred to as “compound (B)”). One type of compound selected from the compounds obtained by treating and removing the first treated compound from compound (B) 7-10 days later, and further 7-10 days later from compound (B) 1 selected from the exception of the compound processed the second time High controlling effect when treating a compound of the class is obtained.

The control method of the present invention can be used for agricultural land such as fields, paddy fields, lawns, orchards, or non-agricultural land.
In addition, the present invention can be used for controlling diseases of the farmland without damaging the plant or the like in the farmland or the like where the “plants” listed below are cultivated.
Agricultural crops: corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, peanut, buckwheat, sugar beet, rapeseed, sunflower, sugar cane, tobacco, etc.
Vegetables: Eggplant vegetables (eggplant, tomatoes, peppers, peppers, potatoes, etc.), cucurbits vegetables (cucumbers, pumpkins, zucchini, watermelon, melon, squash, etc.), cruciferous vegetables (radish, turnip, horseradish, kohlrabi, Chinese cabbage) , Cabbage, mustard, broccoli, cauliflower, etc.), asteraceae vegetables (burdock, garlic, artichoke, lettuce, etc.), liliaceae vegetables (leek, onion, garlic, asparagus), celery family vegetables (carrot, parsley, celery, USA) Bowfish, etc.), red crustacean vegetables (spinach, chard, etc.), perilla vegetables (perilla, mint, basil, etc.), strawberries, sweet potatoes, yam, taros, etc.
Bridegroom,
Foliage plant,
Shiva,
Fruit trees: apples, pears, Japanese pears, quince, quince, etc., nuclear fruits (peaches, plums, nectarines, ume, sweet cherry, apricots, prunes, etc.), citrus (citrus mandarin, orange, lemon, lime, grapefruit) ), Nuts (chestnut, walnut, hazel, almond, pistachio, cashew nut, macadamia nut, etc.), berries (blueberry, cranberry, blackberry, raspberry, etc.), grape, oyster, olive, loquat, banana, coffee, Date palm, coconut palm, etc.
Trees other than fruit trees: Cha, mulberry, flowering trees, street trees (ash, birch, dogwood, eucalyptus, ginkgo, lilac, maple, oak, poplar, redwood, fu, sycamore, zelkova, black bean, peach tree, Tsuga, rat, pine, Spruce, yew) etc.

The above “plant” refers to HPPD inhibitors such as isoxaflutol, ALS inhibitors such as imazetapyr and thifensulfuron methyl, EPSP synthetase inhibitors such as glyphosate, glutamine synthetase inhibitors such as glufosinate, cetoxydim and the like. Plants to which tolerance to herbicides such as acetyl CoA carboxylase inhibitor, bromoxynil, dicamba, 2,4-D, etc. are imparted by classical breeding methods or genetic recombination techniques are also included.
Examples of “plants” that have been given resistance by classical breeding methods include rapeseed, wheat, sunflower, and rice that are resistant to imidazolinone-based ALS-inhibiting herbicides such as imazetapil under the trade name Clearfield (registered trademark). Already sold. Similarly, there are soybeans that are resistant to sulfonylurea ALS-inhibiting herbicides such as thifensulfuron methyl by classical breeding methods, and are already sold under the trade name of STS soybeans. Similarly, SR corn and the like are examples of plants to which tolerance has been imparted to acetyl CoA carboxylase inhibitors such as trion oxime and aryloxyphenoxypropionic acid herbicides by classical breeding methods. Plants tolerant to acetyl-CoA carboxylase inhibitors are the Proceedings of the National Academy of Sciences of the United States of America (Proc. Natl. Acad. Sci). USA), 1990, 87, p. 7175-7179. A mutant acetyl CoA carboxylase resistant to acetyl CoA carboxylase inhibitors is also described in Weed Science, 2005, Vol. 53, p. 728-746, etc., and by introducing such a mutant acetyl CoA carboxylase gene into a plant by gene recombination technology or introducing a mutation related to imparting resistance into a plant acetyl CoA carboxylase, an acetyl CoA carboxylase inhibitor Plants that are resistant to Furthermore, a nucleic acid introduced with a base substitution mutation represented by chimera plastic technology (Gura T.1999. Repairing the Genome's Spelling Mistakes. Science 285: 316-318.) By introducing a site-specific amino acid substitution mutation into an ALS gene or the like, a plant resistant to an acetyl CoA carboxylase inhibitor, an ALS inhibitor or the like can be produced.

  Examples of plants that have been rendered tolerant by genetic recombination technology include glyphosate-resistant maize, soybean, cotton, rapeseed, and sugar beet varieties, which are already sold under trade names such as Roundup Ready (RoundupReady (registered trademark)) and Agriureture GT. Has been. Similarly, there are corn, soybean, cotton, and rapeseed varieties that are resistant to glufosinate by genetic recombination technology, and are already sold under trade names such as Liberty Link (registered trademark). Similarly, bromoxynyl-resistant cotton by gene recombination technology is already sold under the trade name BXN.

The above “plant” includes, for example, a plant capable of synthesizing, for example, a selective toxin known in the genus Bacillus using a gene recombination technique.
Toxins expressed in such genetically modified plants include insecticidal proteins derived from Bacillus cereus and Bacillus popirie; Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C derived from Bacillus thuringiensis Insecticidal proteins such as δ-endotoxin, VIP1, VIP2, VIP3 or VIP3A; nematode-derived insecticidal proteins; toxins produced by animals such as scorpion toxins, spider toxins, bee toxins or insect-specific neurotoxins; filamentous fungal toxins; plants Lectin; agglutinin; protease inhibitors such as trypsin inhibitor, serine protease inhibitor, patatin, cystatin, papain inhibitor; lysine, corn-RIP, abrin, ruffin, saporin, bryodin, etc. Ribosome inactivating protein (RIP); steroid metabolic enzymes such as 3-hydroxysteroid oxidase, ecdysteroid-UDP-glucosyltransferase, cholesterol oxidase; ecdysone inhibitor; HMG-CoA reductase; sodium channel, calcium channel inhibitor, etc. Ion channel inhibitor; juvenile hormone esterase; diuretic hormone receptor; stilbene synthase; bibenzyl synthase; chitinase; glucanase and the like.
Further, as toxins expressed in such a genetically modified plant, Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1, Cry9C, Cry34Ab or Cry35Ab or other δ-endotoxin proteins, VIP1, VIP2, VIP3 or VIPA, etc. Insecticidal protein hybrid toxins, partially defective toxins, and modified toxins are also included. Hybrid toxins are produced by new combinations of different domains of these proteins using recombinant techniques. As a toxin lacking a part, Cry1Ab lacking a part of the amino acid sequence is known. In the modified toxin, one or more amino acids of the natural toxin are substituted.
Examples of these toxins and recombinant plants capable of synthesizing these toxins are described in EP-A-0374753, WO93 / 07278, WO95 / 34656, EP-A-0427529, EP-A-451878, WO03 / 052073 and the like. Are listed.
Toxins contained in these recombinant plants particularly confer resistance to Coleoptera, Hemiptera pests, Diptera pests, Lepidoptera pests and nematodes.

  In addition, genetically modified plants that contain one or more insecticidal pest resistance genes and express one or more toxins are already known and some are commercially available. Examples of these transgenic plants include YieldGard® (a corn variety that expresses Cry1Ab toxin), YieldGard Rootworm® (a corn variety that expresses Cry3Bb1 toxin), YieldGard Plus® (Cry1Ab toxin) Corn varieties expressing Cry3Bb1 toxin), Herculex I® (corn varieties expressing Cry1Fa2 toxin and phosphinotricin N-acetyltransferase (PAT) to confer resistance to glufosinate), NuCOTN33B ( (Registered trademark) (cotton variety expressing Cry1Ac toxin), Bollgard I (registered trademark) (cotton variety expressing Cry1Ac toxin), Bollgard II (registered trademark) Mark) (cotton variety expressing Cry1Ac toxin and Cry2Ab toxin), VIPCOT (registered trademark) (cotton variety expressing VIP toxin), NewLeaf (registered trademark) (potato variety expressing Cry3A toxin), NatureGard (registered trademark) ) Agrisure (registered trademark) GT Advantage (GA21 glyphosate resistant trait), Agrisure (registered trademark) CB Advantage (Bt11 corn borer (CB) trait), Protecta (registered trademark), and the like.

The “plant” includes those imparted with an ability to produce an anti-pathogenic substance having a selective action using a gene recombination technique.
As examples of anti-pathogenic substances, PR proteins and the like are known (PRPs, EP-A-0392225). Such anti-pathogenic substances and genetically modified plants that produce them are described in EP-A-0392225, WO95 / 33818, EP-A-0353191, and the like.
Examples of anti-pathogenic substances expressed in such genetically modified plants include, for example, sodium channel inhibitors, calcium channel inhibitors (KP1, KP4, KP6 toxins produced by viruses, etc.). Ion channel inhibitor; stilbene synthase; bibenzyl synthase; chitinase; glucanase; PR protein; peptide antibiotics, antibiotics having heterocycles, protein factors involved in plant disease resistance (referred to as plant disease resistance gene, WO03 / 000906)) and other anti-pathogenic substances produced by microorganisms. Such anti-pathogenic substances and genetically modified plants that produce them are described in EP-A-0392225, WO95 / 33818, EP-A-0353191, and the like.

  The above “plant” includes plants imparted with useful traits such as oil component modification and amino acid content enhancing traits using genetic recombination techniques. Examples include VISTIVE (registered trademark) (low linolenic soybeans with reduced linolenic content) or high-lysine (high-oil) corn (corn with increased lysine or oil content).

  Furthermore, the above-mentioned classic herbicide traits or herbicide resistance genes, insecticidal pest resistance genes, anti-pathogenic substance production genes, oil traits modification, amino acid content enhancement traits, etc. Combined stack varieties are also included.

  Hereinafter, the present invention will be described in more detail with reference to formulation examples and test examples, but the present invention is not limited to the following examples. In the following examples, parts represent parts by weight unless otherwise specified. Hereinafter, benomyl, thiophanate methyl, carbendazim, iminotadine albesylate, iminotadine acetate, boscalid, fenhexamide, chlorothalonil, respectively, compound II, compound III, compound IV, compound V, compound VI, compound VII, compound VIII May be referred to as Compound IX.

Formulation Example 1
Each emulsion is obtained by thoroughly mixing 3 parts of Compound I, 2 parts of any of Compounds II to IX, 14 parts of polyoxyethylene styryl phenyl ether, 6 parts of calcium dodecylbenzenesulfonate and 75 parts of xylene.

Formulation Example 2
5 parts of Compound I, 5 parts of any of Compound II to Compound IX, 35 parts of a mixture of white carbon and polyoxyethylene alkyl ether sulfate ammonium salt (weight ratio 1: 1) and 55 parts of water are mixed and wet pulverized. Each flowable preparation is obtained by pulverization.

Formulation Example 3
After mixing 28.5 parts of an aqueous solution containing 20 parts of Compound I, 2.5 parts of any of Compounds II to IX, 1.5 parts of sorbitan trioleate and 2 parts of polyvinyl alcohol, and finely pulverized by a wet pulverization method In this, 37.35 parts of an aqueous solution containing 0.05 part of xanthan gum and 0.1 part of aluminum magnesium silicate was added, and further 10 parts of propylene glycol was added and stirred to obtain each flowable preparation.

Formulation Example 4
3 parts of compound I, 2 parts of any of compounds II to IX, 1 part of synthetic hydrous silicon oxide, 2 parts of calcium lignin sulfonate, 30 parts of bentonite and 62 parts of kaolin clay are mixed well and mixed well with water. Then, each granule is obtained by granulating and drying.

Formulation Example 5
Each wettable powder is obtained by thoroughly grinding and mixing 10 parts of Compound I, 40 parts of any of Compounds II to IX, 3 parts of calcium lignin sulfonate, 2 parts of sodium lauryl sulfate, and 45 parts of synthetic hydrous hydroxide.

Formulation Example 6
Each wettable powder is obtained by thoroughly grinding and mixing 2 parts of Compound I, 40 parts of any of Compounds II to IX, 3 parts of calcium lignin sulfonate, 2 parts of sodium lauryl sulfate, and 45 parts of synthetic silicon hydroxide.

Formulation Example 7
Each powder is obtained by thoroughly pulverizing and mixing 3 parts of Compound I, any 2 parts of Compound II to Compound IX, 85 parts of Kaolin clay and 10 parts of talc.

Test Example A plastic pot is filled with sand loam, sown with cucumber (Sagamihanjiro), and grown in a greenhouse for 12 days. The flowable agent of Compound I and the flowable agent of any one of Compound II to Compound IX are each diluted with water and then tank-mixed to contain a predetermined concentration of Compound I and Compound II to Compound IX Prepare a tank mix solution. The tank mix solution is sprayed on the stems and leaves so that it sufficiently adheres to the leaf surface of the cucumber. After spraying, the plants are air-dried, and a hyphae-containing PDA medium of cucumber sclerotia is placed on the cucumber leaf surface. After inoculation, leave it at 12 ° C under high humidity for 6 days, and then check the control effect.
For comparison, the above-described flowable agent of Compound I or the flowable agent of any one of Compounds II to IX is diluted with water, and diluted with water containing any one of Compounds I to IX at a predetermined concentration. Prepare liquids and conduct similar control tests.
In addition, the disease area ratio in each treatment area is investigated for control value calculation.

The control value is calculated from Equation 1.
"Formula 1"
Control value (%) = 100 × (A−B) / A
A: Disease severity of untreated plant B: Disease severity of treated plant Generally, the control effect expected when two kinds of active ingredient compounds are mixed and treated, so-called expected value of control value is It is calculated | required by the calculation formula of the Colby of the following formula 2.
"Formula 2"
E = X + Y− (X × Y) / 100
X: Control value when active ingredient compound A is treated with Mppm Y: Control value when active ingredient compound B is treated with Nppm E: When active ingredient compound A is treated with Mppm and active ingredient compound B is treated with Nppm Expected control value (expected control value)
In addition, a synergistic effect is shown by a value calculated by the following formula 3.
"Formula 3"
Synergy effect = (actual control value) / (expected control value)

  ADVANTAGE OF THE INVENTION According to this invention, the plant disease control composition which has high activity, and the method which can control a plant disease effectively can be provided.

Claims (4)

Formula (I)

A plant disease comprising as an active ingredient a compound represented by the formula: and at least one compound selected from the group consisting of benomyl, thiophanate methyl, carbendazim, iminotadine albecylate, iminocazine acetate, boscalid, fenhexamide, and chlorothalonil Control composition.   The compound represented by the formula (I) according to claim 1 and at least one compound selected from the group consisting of benomyl, thiophanate methyl, carbendazim, iminoctadine albecylate, iminoctadine acetate, boscalid, fenhexamide, and chlorothalonil. The plant disease control composition according to claim 1, wherein the weight ratio is 1: 0.25 to 1: 1.   The compound represented by the formula (I) according to claim 1 and at least one compound selected from the group consisting of benomyl, thiophanate methyl, carbendazim, iminoctadine albecylate, iminoctadine acetate, boscalid, fenhexamide, and chlorothalonil. And a plant disease control method of applying an effective amount to the plant or the soil where the plant is cultivated.   The group consisting of a compound represented by the formula (I) of claim 1 for controlling plant diseases, and benomyl, thiophanate methyl, carbendazim, iminoctadine albecylate, iminoctadine acetate, boscalid, fenhexamide, chlorothalonil Use of a combination with at least one compound selected from.