JP2010279490A - Tubular body for blood supply and removal - Google Patents

Abstract

The present invention provides a blood-feeding / bleeding tubular body comprising a tube made of e-PTFE, etc., all having a uniform surface in contact with blood. Of the artificial blood vessel 2, a tubular body 3 fitted on one end of the artificial blood vessel 2, a flange 4 attached to the tubular body 3, and the like. The tubular body 3 is fitted on the artificial blood vessel 2 from one end portion of the artificial blood vessel 2 having the resin cover 6. The distal end side of the artificial blood vessel 2 is inverted and superimposed on the plate surface of the heel part 3 a, and is sutured to the heel part 3 a by the suture thread 8. Next, the flange 4 is sewn to the flange portion 3a.
[Selection] Figure 1

Description

  The present invention relates to a tube body for blood feeding / deletion suitable for use as a tube member for blood feeding / bleaching such as a cannula attached to a heart.

  As one of the treatments for heart diseases, chronic cardiac function assistance using an auxiliary artificial heart device or an artificial cardiopulmonary assist device is performed. When chronic cardiac function assistance is performed, connection between the artificial blood vessel sutured to the patient's biological blood vessel and the device, and connection to the bypass circuit by the artificial blood vessel to flexibly connect the device to the cannula inserted into the heart Necessary. Various artificial blood vessel connection structures are used at these connection sites.

  JP 2008-279188 describes a cannula for attachment to the heart. Further, FIG. 1 of JP-T-2002-515301 describes a configuration in which a cannula is attached to the heart.

  As a conventional example of a connection structure between a cannula and an artificial blood vessel, there is one described in Patent Document 3 below.

JP 2005-1224859 A Special table 2002-515301 German Patent Application Publication No. 101088813A1

  (1) If there is a step at the joint between the cannula and the artificial blood vessel, a thrombus occurs due to the step. According to the above-mentioned Patent Document 3, although the level difference is considerably small, the presence of the connecting portion means that there is at least one part. In an artificial heart system, if the number of parts increases, the operation becomes complicated, and troubles such as blood leakage, inhalation of air, damage to materials, and risk of infection increase. Moreover, the cost of the whole auxiliary circulation system is also increased. Furthermore, regulatory approval applications will increase labor and time, such as checking the safety of each part and checking the safety of the entire system.

  (2) Even if the artificial blood vessel and the apex cannula are connected successfully, the cannula itself is made of metal, and therefore there is a boundary between the material at the joint between the artificial blood vessel and the cannula. Even a cannula made of titanium, which has good tissue compatibility and adheres to living tissue, becomes a pannus scaffold in blood. Therefore, when titanium is used as the apical cannula, it is excellent in adhesion to the heart wall tissue, but pannus crawls out from the root of the adhering endocardium, and the tissue body broken from the tip of the cannula has a whole body. Fly into the blood circulation.

  An object of the present invention is to solve the above-mentioned conventional problems, and to provide a blood-feeding / bleeding tubular body composed of a tube made of e-PTFE or the like whose surface in contact with blood is all uniform. .

  The tubular body for blood removal / bleeding according to claim 1 comprises a resin tube and a cylindrical body made of a harder material than the tube and fitted on one end of the tube. The portion is inverted and covers at least the outer peripheral surface on the distal end side of the tube.

  According to a second aspect of the present invention, in the first aspect, the tube is made of e-PTFE, and the tube is made of a metal member.

  The blood-feeding / bleeding tubular body according to claim 3 is characterized in that, in claim 2, the metal member is titanium or a titanium alloy.

  According to a fourth aspect of the present invention, there is provided the blood-feeding / bleeding tubular body according to the first or second aspect, wherein a protrusion projecting in the diameter increasing direction is provided on the rear end side of the cylindrical body. .

  According to a fifth aspect of the present invention, in the third aspect, the one end of the tube is connected to the protrusion.

  According to a sixth aspect of the present invention, the blood-feeding / bleeding tubular body according to the third or fourth aspect is characterized in that a flange is attached to the protrusion.

  According to a seventh aspect of the present invention, there is provided a blood-feeding / bleeding tubular body according to any one of the first to fifth aspects, wherein a reinforcing ring is provided on the outer periphery of the tube on the rear side of the tube. .

  In the tubular body for blood removal / bleeding according to the present invention, a tubular body is externally fitted to one end portion (hereinafter sometimes referred to as a distal end portion) of a resin tube, and the one end portion of the tube is inverted to form the tubular body. It covers the body. Therefore, the inner peripheral surface of this blood-feeding / bleeding tubular body is all made up of the resin tube. Since a hard cylindrical body is externally fitted to the distal end portion of the tube, the distal end portion of the blood-feeding / bleeding tubular body is hard and can be used as a core apex cannula. The outer peripheral surface of the distal end portion of the tubular body for blood removal / bleeding is also covered with an inverted resin tube. Therefore, by selecting a material that does not form a thrombus or endocardium, such as e-PTFE, as this resin, no thrombus or endocardium occurs even if the distal end of this blood-feeding / bleeding tubular body comes into contact with blood.

  In addition, since e-PTFE is excellent in elastic stretchability, the e-PTFE tube can be easily reversed and covered with a cylindrical body.

  If a protrusion is provided at the rear part of the cylindrical body, a flange can be attached. By using a sewn material such as a fiber material as the flange, the flange can be sutured to the heart tissue. Since this flange is placed outside the heart, it does not come into contact with blood.

It is the perspective view and sectional drawing of an artificial blood vessel used for manufacturing the tubular body for blood-feeding / bleeding which concerns on embodiment. It is the perspective view and sectional drawing of a cylindrical body. It is sectional drawing of the tubular body for blood-feeding / bleeding in the middle of manufacture. It is sectional drawing of the tubular body for blood-feeding / bleeding in the middle of manufacture. It is sectional drawing of the tubular body for blood sending / bleeding. It is sectional drawing of the state which mounted | wore the heart with the tubular body for blood sending / bleeding.

  Embodiments of the present invention will be described below with reference to the drawings.

  FIG. 1 (a) is a perspective view of an artificial blood vessel used for manufacturing a tubular body for blood sending / deleting according to an embodiment, FIG. 1 (b) is a longitudinal sectional view thereof, and FIG. FIG. 3 and FIG. 4 are cross-sectional views of a tubular body for blood supply and blood removal during manufacture, and FIG. 5 is a cross-sectional view of a tubular body for blood supply and blood removal. FIG. 6 is a cross-sectional view showing a state where the blood-feeding / bleeding tubular body is attached to the heart.

  As shown in FIG. 5, this blood-feeding / bleeding tubular body 1 includes an artificial blood vessel 2 made of a resin tube, a cylindrical body 3 fitted on one end (tip) side of the artificial blood vessel 2, and a cylinder. A flange 4 attached to the body 3 is provided.

  The artificial blood vessel 2 is made of a synthetic resin, preferably e-PTFE. The artificial blood vessel is provided with a reinforcing ring 5. The reinforcing ring 5 is annular or coiled and is wound around the outer periphery of the artificial blood vessel 2. When a commercially available product is purchased, the reinforcing ring 5 is provided from one end of the artificial blood vessel to the other end. In this embodiment, the reinforcing ring 5 is cut and removed at one end of the artificial blood vessel 2, A reinforcing ring 5 is provided on the artificial blood vessel 2 only on the rear side of the shaped body 3.

  The cylindrical body 3 has a substantially cylindrical shape, and is provided with a flange 3a as a protrusion in the vicinity of the rear portion thereof. The flange portion 3 a has an annular shape that goes around the outer periphery of the cylindrical body 3. The flange portion 3a is provided with a plurality of holes 3b penetrating through the flange portion 3a in a direction parallel to the cylindrical axis direction of the cylindrical body 3.

  The hole 3b is for passing a suture as will be described later. A concave groove 3c is provided around the outer peripheral surface of the front portion 3d of the cylindrical body 3 on the tip side of the flange portion 3a.

  The cylindrical body 3 is made of a hard material having a predetermined strength and rigidity such as metal and hard synthetic resin, and is most preferably made of titanium or a titanium alloy.

  The flange 4 is an annular member having an outer diameter larger than the outer diameter of the flange portion 3a and having an inner diameter comparable to that of the cylindrical body 3 other than the flange portion 3a. The flange 4 is preferably made of a non-woven fabric (for example, felt) of synthetic fiber such as polyester, but may be made of a foamed resin such as a foamed polyurethane foam.

  In order to manufacture this blood-feeding / bleeding tubular body 1, as shown in FIG. 1, an artificial blood vessel 2 from which the reinforcing ring 5 is removed at the tip is prepared.

  In this embodiment, a cylindrical resin cover 6 made of a synthetic resin film such as a synthetic resin film such as polyurethane is placed on the outer periphery of the artificial blood vessel 2. The resin cover 6 is preferably formed in a cylindrical shape by dissolving a synthetic resin in a soluble solvent and then applying it to a cylindrical mandrel and evaporating the solvent.

  The resin cover can be easily extracted from the mandrel by being immersed in an insoluble solvent such as acetone and swollen.

  The resin cover 6 is placed from one end to the other end of the artificial blood vessel 2 shown in FIG.

  Next, as shown in FIG. 3, the tubular body 3 is fitted on the distal end side of the artificial blood vessel 2 having the resin cover 6. The cylindrical body 3 is fitted into the artificial blood vessel 2 until it is separated from the tip of the artificial blood vessel 2 by a predetermined distance as shown in the figure.

  Next, first, only the resin cover 6 is reversed and put on the front portion 3 d of the cylindrical body 3. And the band-shaped member 7 (FIG. 4) is wound so that this resin cover 6 may be surrounded, and the resin cover 6 is suppressed. The band-like member 7 is wound around the concave strip 3c.

  Next, as shown in FIG. 4, the distal end side of the artificial blood vessel 2 is reversed. At this time, it is preferable that the tip of the artificial blood vessel 2 is pulled backward while being expanded to cover the tubular body 3. Then, the distal end portion of the artificial blood vessel 2 is superposed on the plate surface of the heel portion 3 a and is sutured to the heel portion 3 a by the suture thread 8. The suture thread 7 is passed through the hole 3b.

  Next, as shown in FIG. 4, the flange 4 is mounted so as to be fitted on the distal end side of the artificial blood vessel 2 with the tubular body 3. The flange 4 has a thin plate shape with a circular opening 4a, and the distal end side of the artificial blood vessel 2 with the tubular body 3 is inserted into the opening 4a. The flange 4 is superposed on the heel part 3a, and is sewn with a suture thread 9 to the heel part 3a. The suture thread 9 is inserted into the hole 3b. Thereby, the tubular body 1 for blood removal / bleeding is obtained.

  In this tubular body 1 for blood removal / bleeding, a tubular body 3 is externally fitted on the distal end side of an artificial blood vessel 2 made of a resin tube, and the distal end portion of the artificial blood vessel 2 is inverted and covers the tubular body 3. Yes. Accordingly, the inner peripheral surface of the blood-feeding / bleeding tubular body 1 is uniformly composed of the artificial blood vessel 2 made of a resin tube. Since the rigid tubular body 3 is externally fitted to the distal end portion of the artificial blood vessel 2, the distal end portion of the tubular body 1 for blood removal / bleeding is hard and can be used as a core apex cannula. The outer peripheral surface of the distal end portion of this blood-feeding / bleeding tubular body is also covered with the inverted artificial blood vessel 2. Therefore, by selecting a material that does not form a thrombus or endocardium, such as e-PTFE, as this resin, no thrombus or endocardium occurs even if the distal end portion of the tubular body for blood removal 1 comes into contact with blood. .

  Since e-PTFE is excellent in elastic stretchability, the tip of the e-PTFE artificial blood vessel 2 can be easily reversed and put on the tubular body 3.

  In this embodiment, a flange 3a is provided at the rear part of the cylindrical body 3, and the flange 4 can be attached. By using a sewn material such as a fiber material as the flange 4, the flange 4 can be sutured to the heart tissue. Since this flange 4 is disposed outside the heart as shown in FIG. 6 described below, it does not come into contact with blood.

  This blood-feeding / bleeding tubular body 1 is attached to the heart 10 as shown in FIG. The flange 4 of the blood-feeding / bleeding tubular body 1 is superimposed on the outer surface of the heart wall, and the flange 4 is sutured to the heart wall by the suture thread 11.

  The above-described embodiment is an example of the present invention, and the present invention may be configured other than illustrated.

1 Tubular body for blood supply and blood removal 2 Artificial blood vessel (resin tube)
3 Tubular body 3a collar (projection)
3b Hole 4 Flange 5 Reinforcement ring 6 Resin cover 7 Band-shaped member 8, 9, 11 Suture thread

Claims (7)

A resin tube;
A tubular body made of a harder material than the tube, and is fitted on one end of the tube, and the one end of the tube is inverted and covers at least the outer peripheral surface of the tube. A tubular body for blood supply and blood removal characterized by the above.   2. The blood-feeding / bleeding tubular body according to claim 1, wherein the tube is made of e-PTFE, and the tube is made of a metal member.   3. The blood-feeding / bleeding tubular body according to claim 2, wherein the metal member is titanium or a titanium alloy.   3. The blood-feeding / bleeding tubular body according to claim 1, wherein a protrusion projecting in a diameter-expanding direction is provided on a rear end side of the tubular body.   4. The blood-feeding / bleeding tubular body according to claim 3, wherein one end of the tube is connected to the protrusion.   5. The blood-feeding / bleeding tubular body according to claim 3, wherein a flange is attached to the protrusion.   6. A blood-feeding / bleeding tubular body according to any one of claims 1 to 5, wherein a reinforcing ring is provided on the outer periphery of the tube on the rear side of the tube.

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