JP2009022518A - Puncture tool with suction cup - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a sucker-attached puncture device capable of achieving high decompression effects, improving the puncture accuracy, and improving the success rate of measurement. <P>SOLUTION: The sucker-attached puncture device 100 has a sucker 13 made of an elastic material on the front end face of a puncture device body 11 having a puncture tool N. The sucker 13 is composed of a shaft part 19, a suction part 21 and an annular recess part 41. The shaft part 19 has a through hole 23 bored in the axial direction for inserting the puncture tool 100. The suction part 21 is connected to the distal end of the shaft part 19, and the front face of the suction part is formed as a concavity 21a. A sample collection port 25 communicating with the through hole 23 to allow the puncture tool N to project is bored at the center of the concavity 21a. The annular recess part 41 is formed concentrically with the sample collection port 25 on the concavity 21a. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a puncture device with a suction cup that punctures with a protruding puncture device and collects blood.

  In recent years, various diseases and the like can be diagnosed by measuring blood obtained by blood collection. In addition, with an increase in the number of diabetic patients, self blood glucose measurement is recommended in which the patient himself / herself monitors blood glucose fluctuations by blood sampling. These blood collections are usually performed using a puncture device equipped with a puncture device. Puncturing with a puncture device is painful, so it is preferable to reduce pain and burden. On the other hand, if the puncture is insufficient, a predetermined blood volume cannot be collected and the measurement may fail. Therefore, in order to improve blood sampling and increase the measurement success rate, a device has been proposed in which after puncturing with a puncture device, the suction means such as a pump is operated to reduce the pressure and suck blood from the puncture hole (for example, (See Patent Documents 1 and 2).

  In these apparatuses, first, a puncture device is loaded into the apparatus, and a fingertip is pressed against the instrument protrusion, and the opening is sealed so as to be in an airtight state. Next, after the fingertip is punctured with a puncture device protruding from the opening, the suction means is operated in this state, and blood is sucked and collected from the puncture hole. This makes it possible to increase the success rate of blood measurement by reducing the pain and burden caused by puncture while obtaining sufficient blood.

JP 2000-014662 A Japanese Patent No. 3668482

However, a puncture device using a conventional puncture device is provided with a suction means, and after the puncture, this suction means is operated to reduce the pressure, and blood is sucked out to improve blood sampling and increase the measurement success rate. However, since a pump for reducing the pressure in the entire apparatus is built in, the apparatus becomes expensive and large. Further, since this vacuum pump must be operated after puncturing or before and after puncturing, there is a problem that the operation becomes complicated and measurement cannot be performed easily. Furthermore, since the entire interior of the apparatus is decompressed and sucked by a decompression pump, the problem of an increase in the amount of blood collected has been included. On the other hand, it is conceivable to use a device that reduces the internal pressure by volume reduction due to temperature change or elastic deformation and sucks blood from the blood sampling part by this pressure reduction. There was a concern that the measurement success rate would decrease due to variations in the puncture position and puncture depth.
The present invention has been made in view of the above situation, and provides a puncture device with a suction cup capable of obtaining a high decompression effect and improving the puncture accuracy, and an object thereof is to improve the measurement success rate. .

The above object of the present invention is achieved by the following configuration.
(1) A suction cup made of an elastic material is provided on the front end surface of the puncture device body having a puncture device,
The suction cup
A shaft portion formed in the axial direction with a through hole through which the puncture device is inserted;
An adsorbing portion in which a sample collection port that is connected to the tip of the shaft portion and has a front surface formed in a concave surface and allows the puncture device to protrude through the through hole is opened in the concave surface;
An annular recess formed concentrically with the sampling port on the concave surface;
A puncture device with a suction cup.

  According to this puncture device with a suction cup, when the front end of the puncture tool main body is pressed against the blood collection part at the time of blood collection, the concave surface of the suction cup adsorption part is closed, and at the same time, the adsorption part and the shaft part are elastically deformed, Air from the concave surface and the annular concave portion is discharged, and at the same time, a puncture device projects from the sample collection port in the central portion of the concave surface to puncture the blood collection portion. After the puncture, the puncture device is pulled out of the blood sampling portion by the elastic restoring force of the suction portion and the shaft portion, but the concave inner space is decompressed without being released by the sucker action, and the blood sucked from the puncture hole is puncture device Guided to a nearby sampling port. At this time, in addition to the closed concave surface, the elastic restoring force of the annular concave portion where the space disappears by pressing contributes to the decompression. In addition, the adsorbing portion is easily deformed by the annular recess, and the puncture device is punctured with high accuracy in the axial direction of the suction cup.

(2) The puncture device with a suction cup according to (1), wherein an annular suction part having a thickness larger than that of the outer peripheral edge and having adhesiveness is extended to the outer peripheral edge of the suction part.

  According to this puncture device with a suction cup, a thick annular suction portion is continuously provided on the outer peripheral edge of the suction portion, so that when the suction portion is pressed against the blood sampling portion, the annular suction portion is predetermined. The sampling surface is flattened by the rigidity of the surface, and the contact property of the adsorption part with the sampling surface is increased. In addition, since the annular adsorbing portion has adhesiveness, the degree of adhesion to the sampling surface is increased, the airtightness is improved, and the suction cup action is further enhanced.

(3) The puncture device with a suction cup according to (1) or (2), wherein a small suction cup is formed concentrically with the sampling port between the sampling port and the annular recess.

  According to this puncture device with a suction cup, when the outer peripheral edge of the suction part is pressed by the blood sampling part, and the suction cup is further pressed in the axial direction, the small suction cup is pressed by the blood sampling part, and then the sample in the central part of the concave surface A puncture device protrudes from the collection port and punctures the blood collection unit. Therefore, immediately before puncturing, the small suction cup and the outer peripheral edge of the suction part are concentrically centered on the puncture instrument and are in close contact with the blood collection part, so that the suction cup is less likely to slip and the puncture accuracy (position And depth).

(4) The puncture device with a suction cup according to any one of claims 1 to 3,
A sensor chip having a reaction part formed so as to be electrically connected to the sensor electrode and supplied with a biological material in the sample;
A biosensor cartridge comprising:

  According to this biosensor cartridge, it is possible to easily supply the sample sucked from the blood sampling part to the reaction part of the sensor chip by depressurizing the concave internal space by the sucker action of the suction part.

(5) The biosensor cartridge according to claim 4 can be loaded, and the biological material in the sample collected by puncturing the subject with the puncture device of the puncture device with a suction cup is measured. Biosensor measurement device.

  According to this biosensor measurement apparatus, since the sample is collected by the biosensor cartridge described above, the measurement is performed as a series of operations from puncture to measurement, and the measurement can be performed easily and reliably.

  According to the puncture device with a suction cup according to the present invention, when the blood is collected, the concave surface of the suction cup suction portion is closed, and when the suction portion and the shaft portion are elastically deformed, the air between the concave surface and the annular recess is discharged simultaneously. The puncture device protrudes from the sample collection port at the center of the concave surface, and punctures the blood collection unit. After the puncture, the puncture device is pulled out of the blood collection portion by the elastic restoring force of the suction portion and the shaft portion, but the concave inner space is decompressed without being released by the sucker action, and the blood sucked from the puncture hole is puncture device Guided to a nearby sampling port. At this time, in addition to the closed concave surface, the elastic restoring force of the annular concave portion in which the space disappears by pressing contributes to the decompression, thereby preventing insufficient suction.

Hereinafter, preferred embodiments of a puncture device with a suction cup according to the present invention will be described with reference to the drawings.
The embodiment disclosed this time should be considered as illustrative in all points and not restrictive. The scope of the present invention is defined by the terms of the claims, rather than the meanings described above, and is intended to include any modifications within the scope and meaning equivalent to the terms of the claims.
FIG. 1 is a configuration diagram showing a front end face of a puncture device with a suction cup according to the present invention in (a) and a cross section parallel to the axis in (b).
The puncture tool with a suction cup 100 according to this embodiment is mainly divided into a puncture tool main body 11 and a suction cup 13. The puncture tool body 11 has a puncture instrument N. More specifically, the puncture device body 11 formed in a substantially columnar shape is provided with an insertion hole 15 in the axial direction, and the insertion hole 15 is inserted through the puncture device N. The puncture device N has a base end (not shown) fixed to the puncture device body 11, loosely fitted in the insertion hole 15, and protruded from the front end surface of the puncture device body 11. Examples of the puncture device N include a needle, a lancet needle, a cannula, and the like.

  A suction cup 13 is coaxially fixed to the front end surface of the puncture tool body 11 from which the puncture device N is protruded from the insertion hole 15, and the suction cup 13 is made of an elastic material. This elastic material contains any of natural rubber, synthetic rubber, and sponge. The synthetic rubber preferably contains at least one of silicone rubber, urethane rubber, acrylic rubber, styrene butadiene rubber, ethylene propylene rubber, and fluorine rubber. Specifically, rubber or sponge made of polymer or copolymer such as silicone, urethane, acrylic, ethylene, styrene, polyolefin such as polyethylene and polypropylene, polyester such as polyethylene terephthalate and polybutylene terephthalate, polytetrafluoro Fluorine resin such as PFA which is a copolymer of ethylene and perfluoroalkoxyethylene and polyfluoroethylene can be used.

  The suction cup 13 includes a shaft portion 19 and a suction portion 21. A through-hole 23 is bored in the axial direction in a columnar shaft portion 19 formed with substantially the same diameter as the puncture device body 11, and the through-hole 23 is connected coaxially with the insertion hole 15.

  A circular suction portion 21 is connected to the tip of the shaft portion 19, and the front surface of the suction portion 21 is formed as a concave surface 21 a. A sample collection port 25 is opened at the center of the concave surface 21a, and the sample collection port 25 can pass through the through-hole 23 to allow the puncture device N to protrude.

  The puncture device N protruding from the insertion hole 15 is inserted into the through hole 23 of the shaft portion 19, and the tip of the puncture device N is disposed on the back side from the sample collection port 25. That is, normally, the puncture device N is not protruded from the sample collection port 25. The shaft portion 19 and the suction portion 21 can be compressed and deformed in the axial direction by being made of the above-described elastic material. Therefore, when the puncture device main body 11 is pressed by a blood collection part (not shown), the adsorption part 21 and the shaft part 19 are compressed and deformed in the axial direction by the reaction force from the blood collection part, and the tip of the puncture device N is It protrudes from the sample collection port 25 with a predetermined length. The predetermined length here refers to the puncture depth necessary to obtain the minimum amount of blood from the blood collection part.

  The puncture device main body 11 is provided with an exhaust passage 27, and the exhaust passage 27 extends in the radial direction of the puncture device main body 11, and one end is opened to the insertion hole 15, and the other end is the outer peripheral surface of the puncture device main body 11. It opens to the outside. That is, the exhaust path 27 allows the insertion hole 15 to communicate with the outside. The exhaust passage 27 is provided with a backflow prevention valve 29, which is formed in the vicinity of the outlet of the exhaust passage 27 that opens to the outer periphery of the puncture tool body 11 in the present embodiment. The backflow prevention valve 29 is made of, for example, a thin elastic sheet piece such as silicon, and a part of the outer periphery is fixed to the puncture device main body 11 to block the opening of the exhaust passage 27. That is, the backflow prevention valve 29 discharges air from the exhaust passage 27, while preventing outside air from entering the exhaust passage 27 from the outside. As a result, the backflow prevention valve 29 opens in response to the pressurization inside the closed concave surface 21a and operates to close in response to the depressurization.

  Thus, in the puncture device with a suction cup 100 provided with the backflow prevention valve 29, when the front end of the puncture tool main body 11 is pressed by the blood collection part, the concave surface 21a of the suction cup suction part 21 is closed simultaneously with the suction part. 21 and the shaft part 19 are elastically deformed, and the internal space of the concave surface 21a is pressurized. This pressurized air passes through the sample collection port 25, the through hole 23, the insertion hole 15, and the exhaust path 27 and is discharged from the backflow prevention valve 29 to the outside. Thereby, the pressure to the blood collection part of the suction cup 13 becomes possible smoothly. Further, the skidding of the suction cup 13 due to exhaust from the suction cup periphery is eliminated. In the puncture device 100, after puncturing, the puncture device N is pulled out from the blood collection portion by the elastic restoring force of the suction portion 21 and the shaft portion 19, and the concave inner space is shifted to a reduced pressure state. The exhaust path 27 is closed, and the adsorbing part 21 comes into close contact with the blood sampling part by the suction cup action.

  The puncture device 100 is provided with suction release means, and the suction release means opens the inside of the concave surface 21a, whose front surface is closed and becomes negative pressure, to the atmosphere. The suction release means includes an intake passage 33 formed in the suction portion 21 and an adhesive lid 35 that seals the intake passage 33 so as to be openable. The adhesive lid 35 can be provided with adhesiveness by sticking a gel adhesive tape. By using the gel pressure-sensitive adhesive tape, it is possible to ensure high airtightness and make it difficult to leak air while improving the peelability at the time of releasing the adsorption.

  An annular protrusion 39 projects from the periphery of the sample collection port 25, and the annular protrusion 39 abuts on the blood collection part. An annular recess 41 is formed around the annular protrusion 39 on the concave surface 21 a, and the annular recess 41 is formed concentrically with the sample collection port 25. In the annular recess 41, when the annular protrusion 39 is brought into contact with the blood collection part and the shaft part 19 is compressed and deformed, most of the space in the recess disappears due to the elastic deformation of the suction part 21. The suction cup 13 can perform stable puncture by regulating the puncture amount (depth) of the puncture device N by the annular projection 39 coming into contact with the blood collection part.

  An annular suction portion 43 extends and is continuously formed (extended) on the outer peripheral edge of the suction portion 21, and the annular suction portion 43 is thicker than the outer peripheral edge. Moreover, the surface continuous with the concave surface 21a of the annular suction portion 43 has adhesiveness. This adhesiveness can be imparted by a gel adhesive tape or the like, similar to the adhesive lid 35. The suction cup 13 is continuously provided with a thick annular suction portion 43 on the outer peripheral edge of the suction portion 21, so that when the suction portion 21 is pressed by the blood collection portion, the annular suction portion 43 has a predetermined shape. The sampling surface is flattened by the rigidity, and the contact property of the suction part 21 with respect to the sampling surface is increased. In addition to this, since the annular suction portion 43 has adhesiveness, the degree of adhesion to the sampling surface is increased, the airtightness is improved, and the suction cup action is further enhanced.

The operation of the puncture device with a suction cup 100 will be described.
When the front end of the puncture device with suction cup 100 is pressed by the blood sampling part, the concave surface 21a of the suction cup suction part 21 is closed, and at the same time, the suction part 21 and the shaft part 19 are elastically deformed, and the internal space of the concave surface 21a The internal space of the annular recess 41 is pressurized. The pressurized air passes through the sample collection port 25, the through hole 23, the insertion hole 15, and the exhaust path 27 and is discharged from the backflow prevention valve 29 to the outside. At the same time, the puncture device N protrudes from the sample collection port 25 at the center of the concave surface, and punctures the blood collection unit. Pressurized air is not discharged from the intake passage 33 sealed by the adhesive lid 35.

  After the puncture, the puncture device N is pulled out of the blood collection portion by the elastic restoring force of the adsorbing portion 21 and the shaft portion 19, and the internal space of the concave surface 21a and the annular concave portion 41 is shifted to a reduced pressure state. Closes the exhaust passage 27, the suction part 21 is decompressed without being opened by the suction cup action, and comes into close contact with the blood sampling part. Outside air does not flow in from the intake passage 33 sealed by the adhesive lid 35. The blood sucked from the puncture hole by this decompression is guided to the sample collection port 25 in the vicinity of the puncture device.

  The suction portion 21 that has collected blood into the sample collection port 25 is pulled by the slide portion 37, whereby the adhesive lid 35 is peeled off, air from the outside flows in from the intake passage 33, the inside of the concave surface is opened to the atmosphere, and vacuum suction is performed. The state is released. Further, since the air directly flows into the concave surface by opening the adhesive lid 35, the blood flowing into the sampling port 25 does not flow backward. Furthermore, since blood does not flow backward, the adhesion of blood to the blood collection part can be reduced.

  According to this puncture device with a suction cup 100, the suction cup 13 is provided on the front end surface of the puncture tool body 11 from which the puncture tool N is projected, and the suction cup 13 is connected to the shaft portion 19 through which the puncture tool N is inserted, and the shaft. A sample collection port 25 that is connected to the tip of the unit 19 and has a front surface formed on the concave surface 21a and allows the puncture instrument N to protrude is formed in the center of the concave surface 21a, and a sample collection port is formed on the concave surface 21a. 25 and the annular recess 41 formed concentrically. When the blood is collected, the concave surface 21a of the suction cup suction portion 21 is closed, and when the suction portion 21 and the shaft portion 19 are elastically deformed, the concave surface 21a and the annular concave portion are provided. At the same time, the puncture device N is projected from the sample collection port 25 in the central part of the concave surface, and punctures the blood collection unit. After the puncture, the puncture device N is pulled out from the blood collection portion by the elastic restoring force of the suction portion 21 and the shaft portion 19, but the concave inner space is decompressed without being released by the sucker action, and the blood sucked from the puncture hole is removed. It is guided to the sample collection port 25 in the vicinity of the puncture device. At this time, in addition to the closed concave surface 21a, the elastic restoring force of the annular concave portion 41 in which the space disappears by pressing contributes to the decompression and prevents the suction from being insufficient. That is, since the annular recess 41 to be expanded and contracted is provided, the pressure reducing action accompanying the increase in volume after the contraction of the annular recess 41 can also contribute to the blood suction action, and a larger suction effect can be obtained.

  Moreover, since the adsorption | suction part 21 becomes easy to deform | transform with the annular recessed part 41, the puncture instrument N can be punctured with high precision in the axial direction of the suction cup 13, and stable puncture can be performed. As a result, the puncture accuracy (position and depth) can be increased, the shortage of suction pressure can be resolved, and the measurement success rate can be improved.

  In the above embodiment, the puncture device N is inserted through the insertion hole 15 of the puncture device main body 11. However, the insertion hole 15 may be omitted and the puncture device N may protrude from the front end surface of the puncture device main body 11. . In such a case, the exhaust passage 27 can be formed in the shaft portion 19 of the suction cup 13.

Next, a second embodiment of the puncture device with a suction cup according to the present invention will be described.
FIG. 2 is a configuration diagram showing a front end face of the puncture device with a suction cup according to the second embodiment in (a) and a cross section parallel to the axis in (b). In the following embodiments, members that are the same as those shown in the other drawings are given the same reference numerals, and redundant descriptions are omitted.
The puncture device with suction cup 200 according to this embodiment does not include the exhaust passage 27 and the backflow prevention valve 29 in the puncture device main body 11A. On the other hand, the annular recess 41 of the suction portion 21 is provided with a pair of exhaust ports 33A sandwiching the annular protrusion 39, and the exhaust ports 33A are formed by, for example, slits. The slit is formed so that the suction portion 21 is opened by being compressed and deformed in the axial direction, while the suction portion 21 is closed again in the process of returning to the original shape by the elastic restoring force.

  According to the puncture device 200 with the suction cup, when the suction portion 21 and the shaft portion 19 are elastically deformed and the concave internal space is pressurized, the pressurized air is directly exhausted from the exhaust port 33A. And puncture accuracy (position and depth) can be improved.

The puncture devices with suction cups 100 and 200 are not limited to the shape of the suction portion 21 shown in the figure, and can be formed by the following various modifications.
FIG. 3 is a cross-sectional view showing variations in the shape of the adsorbing portion with (a) to (e).
That is, as shown in FIG. 3 (a), the suction cup piercing tool 200A of the suction cup 13B is formed with an annular recess 41a deeper than the annular recess 41 and having an annular suction portion 43a having an extended length longer than the annular suction portion 43. Good. According to this puncture device 200A, the annular suction portion 43a increases the contact area, makes it difficult for air to flow in, and improves the adhesion, while increasing the volume of the annular recess 41a to further increase the suction pressure. Can be increased.

As shown in FIG. 3 (b), a sucker-attached puncture tool 200 </ b> B of the suction cup 13 </ b> C in which an annular recess 41 b shallower than the annular recess 41 is formed.
As shown in FIG.3 (c), it is good also as 200C of suction cups with suction cups of the suction cup 13D which formed the annular recessed part 41c shallower than the annular recessed part 41b.
As shown in FIG.3 (d), it is good also as the puncture tool 200D with a suction cup of the suction cup 13E which formed the annular recessed part 41d with the shallow and standing inner wall.
As shown in FIG.3 (e), it is good also as the puncture tool 200E with a suction cup of the suction cup 13F which formed the annular recessed part 41e with the shallow and gentle inclination.

Next, a third embodiment of a puncture device with a suction cup according to the present invention will be described.
FIG. 4: is the block diagram which represented the puncture tool with a suction cup which concerns on 3rd Embodiment provided with the small suction cup in (a), and the modification is shown in (b).
The puncture tool with suction cup 300 according to this embodiment includes a suction cup 13G on which a small suction cup 51 is formed. That is, a small suction cup 51 is formed between the sample collection port 25 and the annular recess 41 a, and the small suction cup 51 is formed concentrically with the sample collection port 25. As shown in FIG. 4B, the puncture device with suction cup 300A may be a suction cup 13H in which the annular recess 41e is formed with a shallow and gentle inclination.

  According to this puncture device with a suction cup 300, when the outer peripheral edge of the suction cup 13G is pressed by the blood sampling part and the suction cup 13G is further pressed in the axial direction, the small suction cup 51 is pressed by the blood sampling part, and then the concave center The puncture device N protrudes from the sample collection port 25 of the unit, and punctures the blood collection unit. Therefore, immediately before puncture, the small suction cup 51 and the outer peripheral edge of the suction part are concentrically centered around the puncture instrument N and are in close contact with the blood collection part, so that the side suction of the suction cup 13G hardly occurs and the puncture is performed. Increases accuracy (position and depth).

Next, a fourth embodiment of the puncture device with a suction cup according to the present invention will be described.
FIG. 5 is a cross-sectional view showing variations of the shape of the suction portion according to the fourth embodiment by (a) to (e).
Puncture tools with suction cups 400A to 400E according to this embodiment have small suction cups 51 and exhaust ports 33A, and suction cups 13J to 13N are formed in different suction part shapes. Puncture tools with suction cups 400A to 400E exhibit the action of the small suction cup 51, the action of the exhaust port 33A, and the action depending on the shape of each suction portion in a composite manner. Variations in the shape of the suction portion can be as follows.

That is, as shown in FIG. 5 (a), the suction cup piercing tool 400A of the suction cup 13J is formed with an annular recess 41a that is deeper than the annular recess 41 and has an annular suction portion 43a that extends longer than the annular suction portion 43. Good.
As shown in FIG. 5 (b), a sucker-attached puncture tool 400 </ b> B of the suction cup 13 </ b> K in which an annular recess 41 b shallower than the annular recess 41 is formed.
As shown in FIG.5 (c), it is good also as puncture tool 400C with a suction cup of the suction cup 13L which formed the annular recessed part 41c shallower than the annular recessed part 41b.
As shown in FIG.5 (d), it is good also as puncture tool 400D with a suction cup of the suction cup 13M which formed the annular recessed part 41d with the shallow and standing inner wall.
As shown in FIG. 4E, a sucker-attached puncture tool 400E of a suction cup 13N in which an annular recess 41e is formed with a shallow and gentle inclination may be used.

Next, a fifth embodiment of a puncture device with a suction cup according to the present invention will be described.
FIG. 6 shows a puncture device with a suction cup according to a fifth embodiment with a different backflow prevention valve, (a), a configuration diagram showing a modified example thereof, and FIG. 7 shows a puncture device with a suction cup shown in FIG. It is operation | movement explanatory drawing which represented the valve opening / closing process of (a)-(c).
In the puncture device with suction cup 500 according to this embodiment, the shaft portion 57 is made of the same elastic material as described above, and is formed into a abacus ball shape having a small diameter at both ends in the axial direction and a large diameter at the central portion of the axis. A sheath tube 59 is formed inside the shaft portion 57, and both ends of the inner through-hole 63 are connected to the insertion hole 15 of the puncture tool body 11 </ b> B and the sample collection port 25. That is, the puncture instrument N is arranged in the sheath tube 59 in the same manner as the through hole 23 described above. An annular space 61 that surrounds the sheath tube 59 is formed inside the shaft portion 57, and the annular space 61 can be opened to the outside via the backflow prevention valve 65.

  The puncture device main body 11B is formed with a bypass passage 15a, and one end of the bypass passage 15a is connected to the insertion hole 15 and the other end is connected to the annular space 61.

  The shaft portion 57 is compressed and deformed in the axial direction. The sheath tube 59 also has a large diameter central portion in the axial direction, and can be compressed and deformed in the axial direction. By compressing the shaft portion 57 and the sheath tube 59, the volume of the annular space 61 is reduced and restored.

  The shaft portion 57 is provided with a pair of backflow prevention valves 65, and the backflow prevention valves 65 are disposed at both ends of the shaft portion 57 in the diameter direction. A slit is formed in the backflow prevention valve 65, and the slit forms an opening 65a as shown in FIG. 7 by compressing and deforming the shaft portion 57 in the axial direction. The opening 65a is formed so as to be closed again in the process in which the shaft portion 57 returns to its original shape by an elastic restoring force.

  In addition, as shown in FIG. 6B, the puncture device 500 with the suction cup has a secondary backflow prevention valve 65a that is opened and closed in the same manner as the backflow prevention valve 65 as the shaft portion 57 and the sheath tube 59 are compressed and deformed. It is good also as puncture tool 500A with a suction cup provided in the sheath tube 59. In the figure, 21A indicates a mortar-shaped adsorption portion according to a modification, and 21Aa indicates a concave surface thereof.

  In the suction puncture blood sampling method using the puncture device with a suction cup 500, as shown in FIG. 7A, when the suction portion 21A is brought close to the blood collection portion and the puncture device with a suction cup 500 is pressed, FIG. As shown in FIG. 4, the suction portion 21A is closed and simultaneously receives the reaction force F from the blood sampling portion. By this reaction force F, the adsorbing portion 21A and the shaft portion 57 are compressed and deformed in the axial direction from d to D. The backflow prevention valve 65 is opened by this compression deformation, and the air remaining in the concave inner space and the air in the annular space 61 are discharged from the opening 65 a of the backflow prevention valve 65. At the same time, the puncture device N is projected from the sample collection port 25 opened in the center of the concave surface, and punctures the blood collection unit.

  As shown in FIG. 7C, the puncture device with suction cup 500 immediately after puncturing the blood collection unit, the puncture device N is pulled out of the blood collection unit by the elastic restoring force f of the adsorption unit 21A and the shaft unit 57. However, the concave inner space is decompressed without being opened by the suction cup action because the backflow prevention valve 65 is closed again. At this time, an increase in the volume of the annular space 61 due to the restoration of the shaft portion 57 also contributes to the pressure reducing action. As a result, the concave surface 21Aa comes into close contact with the blood sampling part, and the blood sucked from the puncture hole by this pressure reduction is efficiently guided to the sample sampling port 25 in the vicinity of the puncture device.

  Thus, according to the puncture device with suction cup 500, it is possible to perform suction puncture blood collection without requiring a decompression pump or a decompression operation after puncture. Further, since natural decompression acts on the blood collection part, the necessary minimum amount of blood collection is guided to the sample collection port 25 with high efficiency, and the blood collection amount does not increase more than necessary. In addition, since the annular space 61 to be expanded and contracted is provided in the shaft portion 57, the decompression action accompanying the increase in volume after the contraction of the annular space 61 can also contribute to the blood suction action, and a greater suction effect can be obtained. Obtainable.

Next, the biosensor cartridge according to the present invention will be described.
FIG. 8 is a view showing a longitudinal section of a biosensor cartridge provided with the puncture device with a suction cup 100 described above. In addition, the same code | symbol is attached | subjected to the same part and site | part as the previous puncture tool 100 with a suction cup, and the overlapping description shall be abbreviate | omitted.

The biosensor cartridge 600 includes a puncture device main body 11 having a puncture device N and a sensor chip 610 formed integrally with the puncture device main body 11.
The sensor chip 610 has a three-layer structure in which a spacer layer is sandwiched between two substrates (not shown) that are opposed to each other, and sensor electrodes 612a, 612b is provided.
The sensor electrodes 612a and 612b are bent toward each other on the front end side (upper side in FIG. 8) of the puncture device main body 11, and are spaced apart from each other while maintaining a predetermined interval.
The sensor chip 610 is formed so as to be electrically connected to the sensor electrodes 612a and 612b through the portions where the sensor electrodes 612a and 612b are bent and overlapped, and the sample is passed through the sample collection port 25 of the suction cup 13. A reaction unit 614 to which the biological material therein is supplied is provided.

For example, a reagent 616 that immobilizes an enzyme and a mediator and reacts with glucose in blood B to generate an electric current is provided immediately above or in the vicinity of the sensor electrodes 612a and 612b in the reaction unit 614. Therefore, the reaction part 614 becomes a part where the blood B introduced from the sample collection port 25 undergoes a biochemical reaction with the reagent 616.
In FIG. 8, the exhaust passage 27 and the backflow prevention valve 29 (both see FIG. 1) are omitted.

  According to this biosensor cartridge 600, the concave inner space is depressurized by the sucking action of the adsorbing part 21, whereby the blood B sucked from the blood sampling part can be easily supplied to the reaction part 614 of the sensor chip 610.

Next, the biosensor measuring apparatus according to the present invention will be described.
FIG. 9 shows a configuration of a biosensor measurement apparatus 700 using the biosensor cartridge 600 shown in FIG. In addition, the same code | symbol is attached | subjected to the same part and site | part as the previous biosensor cartridge 600, and the overlapping description shall be abbreviate | omitted.

  The biosensor measuring apparatus 700 is configured to be loaded with the biosensor cartridge 600 described above, and connected to the sensor electrodes 612a and 612b of the loaded biosensor cartridge 600 to obtain information on blood B collected, and a measuring device 710 A protective cap 712 that protects the loaded biosensor cartridge 600 is provided.

  The measuring device 710 includes a power source 714, a control device 716, a terminal insertion unit 718, and a display unit 720, which are connected to each other. The rear end portion 11b (see FIG. 8) of the biosensor cartridge 600 is inserted into the terminal insertion portion 718 to fix and hold the biosensor cartridge 600, and the sensor electrodes 612a and 612b exposed at the rear end portion 11b are electrically connected. Connected.

  According to this biosensor measuring apparatus 700, since the sample is collected by loading the biosensor cartridge 600 described above, the measurement is performed as a series of operations from the puncture to the measurement. It can be carried out.

It is the block diagram which represented the front end surface of the puncture device with a suction cup which concerns on this invention to (a), and represents the cross section parallel to an axis line in (b). It is the block diagram which represented the front end surface of the puncture tool with a suction cup which concerns on 2nd Embodiment to (a), and represented the cross section parallel to an axis line to (b). It is sectional drawing showing the variation of the adsorption | suction part shape of 2nd Embodiment by (a)-(e). It is the block diagram which represented the puncture tool with a suction cup which concerns on 3rd Embodiment provided with the small suction cup in (a), and its modification example in (b). It is sectional drawing showing the variation of the adsorption | suction part shape of 4th Embodiment by (a)-(e). It is the block diagram which represented the puncture device with a suction cup which concerns on 5th Embodiment from which a backflow prevention valve differs in (a), and its modification example in (b). It is operation | movement explanatory drawing which represented the valve opening and closing process of the puncture device with a suction cup shown in FIG. 6 by (a)-(c). It is sectional drawing which shows one Embodiment of the biosensor cartridge which concerns on this invention. It is a block diagram which shows one Embodiment of the biosensor measuring apparatus which concerns on this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 11 Puncture tool main body 13 Suction cup 15 Insertion hole 19 Shaft part 21 Adsorption part 21a Concave surface 23 Through-hole 25 Sampling port 41 Annular recessed part 43 Annular adsorption part 51 Small suction cups 100, 200, 300, 400A to E, 500 Puncture with suction cup N Puncture device

Claims (5)

A suction cup made of an elastic material is provided on the front end surface of the puncture device body having a puncture device,
The suction cup
A shaft portion formed in the axial direction with a through hole through which the puncture device is inserted;
An adsorbing portion in which a sample collection port that is connected to the tip of the shaft portion and has a front surface formed in a concave surface and allows the puncture device to protrude through the through hole is opened in the concave surface;
An annular recess formed concentrically with the sampling port on the concave surface;
A puncture device with a suction cup.   The puncture device with a suction cup according to claim 1, wherein an annular suction portion having a thickness larger than that of the outer peripheral edge and having adhesiveness is extended to the outer peripheral edge of the suction portion.   The puncture device with a suction cup according to claim 1 or 2, wherein a small suction cup is formed concentrically with the sample collection port between the sample collection port and the annular recess. A puncture device with a suction cup according to any one of claims 1 to 3,
A sensor chip having a reaction part formed so as to be electrically connected to the sensor electrode and supplied with a biological material in the sample;
A biosensor cartridge comprising:   A biosensor measurement, wherein the biosensor cartridge according to claim 4 can be loaded, and a biological material in a sample collected by puncturing the subject with a puncture device of the puncture device with a suction cup is measured. apparatus.

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