JP2009013128A - Skin care preparation for external use and oral composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a preparation applied to the skin and a preparation applied to an oral cavity that exhibit more excellent effects than conventional preparations comprising a plant extract as an effective ingredient. <P>SOLUTION: The skin care preparation for external use comprises an oily extract obtained from a plant using, as an extracting medium, at least one selected from the group consisting of sesame oil, milk, coconut oil, beeswax, Melia azadirachta seed oil, castor oil and milk fat. The oral composition comprises an oily extract obtained from a plant using, as an extracting medium, at least one from among sesame oil, milk, coconut oil, beeswax, Melia azadirachta seed oil, castor oil and milk fat. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an external preparation for skin and an oral composition containing an oily extract extracted from plants as an active ingredient.

  Conventionally, various plant components and plant extracts have been proposed as active ingredients for external preparations for skin and oral compositions. For example, capsaicin and mugwort extract are known to exhibit a blood circulation promoting action (see Patent Documents 1 and 2), and have been used to promote skin metabolism and maintain moist and youthful skin. On the other hand, research on medicinal herbs and medicinal trees that have been used for a long time is also being conducted. There is a need for an active ingredient that can be further blended into an external preparation for skin and a composition for the oral cavity and has a higher effect without side effects.

Japanese Patent Laid-Open No. 10-194935 Japanese Patent Laid-Open No. 11-1428

  An object of the present invention is to provide a preparation for application to the skin and a preparation for application to the oral cavity, which can exhibit a more excellent effect than a preparation containing a conventional plant extract as an active ingredient. . More specifically, an object of the present invention is to provide an external preparation for skin and a composition for oral cavity that have no side effects, have a good feeling of use, and can exhibit excellent effects.

As a result of intensive research to achieve the above-mentioned problems, the present inventors have applied oily extracts obtained by boiling plants in a predetermined extraction medium to the skin or oral cavity, thereby preventing various symptoms. As a result, the present invention has been completed.
Therefore, the present invention provides an external skin containing an oily extract obtained from a plant using at least one selected from the group consisting of sesame oil, milk, coconut oil, beeswax, melia azadiracta seed oil, castor oil and milk fat as an extraction medium. It is an agent. The present invention is also an oral composition comprising an oily extract obtained from a plant using at least one of sesame oil, milk, coconut oil, beeswax, Melia azadiracta seed oil, castor oil and milk fat as an extraction medium.
More specifically, the oily extract obtained from the above plant used as an active ingredient in the present invention is selected from the group consisting of sesame oil, milk, coconut oil, beeswax, melia azadiracta seed oil, castor oil and milk fat. In at least one kind, the plant is boiled, and then the mixture is solid-liquid separated to remove the solid content.
Therefore, the present invention is to boil a plant in at least one selected from the group consisting of sesame oil, milk, coconut oil, beeswax, melia azadiracta seed oil, castor oil and milk fat, and then solid-liquid separate the mixture. The present invention is directed to an external preparation for skin containing an oily composition obtained by removing solids. The present invention also includes boiled a plant in at least one selected from the group consisting of sesame oil, milk, coconut oil, beeswax, Melia azadilacta seed oil, castor oil and milk fat, and then solid-liquid separated the mixture. The present invention is directed to an oral composition containing an oily composition obtained by removing a solid content.

In the present invention, the plant includes Mylobaran, Seitamirobaran, Ammacro, Doricos wing irata, snake cucumber, fern cordiphoria, Takasaburo, Nanbanai, Akane, Sasahagi, Aerbaranata, eggplant, Soranum virginianum, Hamabishi, Sorizayanaki, Bengal Karatachi, Kidachi Kibana Yoraku, Stereosperms Abeolence, Premna Serachihoria, Indian Yaitbana, Melia Azadiracta, Asparagus Lasemosus, Ginko, Witania Somnifera, Aerbara Natahabishi, Nankyosou, Wasabi, Oba Beckei, Nambang Akazuki, Justiacia adhatda, Blackonna, Thai carrot, Tamarind, etc. are mentioned. Therefore, in the present invention, the plant is Myrobalan, Seitamirobaran, Ammacro, Dorikos wing irata, Snake cucumber, fern cordiphoria, Takasaburo, Nanbanai, Akane, Sasahagi, Aerbaranata, eggplant, Solanum virginianum, Hamabishi, Sorizayanoki, Bengal Karatachi, Kidachi Kibana Yoraku, Stereosperms Abeolence, Premna Serachihoria, Indian Yaitbana, Melia Azadiracta, Asparagus Lasemosus, Ginko, Witania Sounifera, Aerbara Natahabishi, Nankyosou, Wasabikino, Greenback It is possible to use at least one selected from redwood, justia adhatda, kuroyona, taiwan carrot, and tamarind.
The part used for the extraction of the plant is not particularly limited, and any part such as root, stem, leaf, fruit, seed, bark and the like may be used.
The skin external preparation of the present invention is directed to uses such as ordinary cosmetics such as external pharmaceutical preparations, pharmaceutical cosmetics (quasi-drugs), and cosmetics.

The oily extract from the plant used in the present invention has an effect of improving poor blood circulation and skin conditions caused by photoaging, skin aging and stress, rough skin, wrinkles, spots, etc., anti-inflammatory effect, atopic dermatitis, rough skin, Improvement of skin condition such as psoriasis / dry skin, improvement of skin condition of sensitive skin, improvement and healing effect of dermatitis, healing of scar, moisturizing effect of skin and hair, lipolysis, removal of cellulite, migraine Relaxation, sleep improvement, hair gloss effect, hair growth promotion effect, dandruff improvement effect, white hair suppression effect, stiff shoulder, low back pain, neuralgia, joint pain improvement and healing effect, muscle pain relief and improvement effect, rhinitis・ It is excellent in alleviating and improving the inflammation of the tonsils, and the recovery effect of physical fatigue. By blending it as a component of a skin external preparation, it provides a skin external preparation excellent in the above-mentioned effects. Can.
Moreover, the oily extract from the plant used in the present invention provides an oral composition that exerts effects of promoting blood circulation of the gums, protecting the oral mucosa, and mitigating stomatitis by being blended as a component of the oral composition. be able to.
The oily extract from plants used in the present invention is highly safe and has very few side effects.

  The extraction medium used to obtain the plant oily extract used in the present invention is at least one selected from the group consisting of sesame oil, milk, coconut oil, beeswax, melia aziracta seed oil, castor oil and milk fat. These may be used alone or in combination of two or more. For example, a combination of sesame oil and milk, coconut oil alone, a combination of sesame oil and beeswax, a combination of sesame oil, Melia azadiracta seed oil, castor oil, and milk fat. When two or more types of extraction media are used in combination, their ratio is suitably in the range from the same amount to 10 times the mass, and preferably in the range from the same amount to 5 times the amount. For example, when a combination of sesame oil and milk is used, the appropriate mass ratio is 1:10 to 10: 1.

Examples of plants that can be used as the raw material for the extraction include milobaran, seitaka mirobaran, anmacro, dorikos wing irata, snake cucumber, fern cordiphoria, takasaburo, nambanai, akane, sasahagi, aerbaranata, eggplant, solanum virginianum, hamabishi, sorizayanaki, bengal karatachi, Scarlet terrestris, stereosperm aveolens, premna cerachihoria, Indian Yaitana, Melia Azadiracta, Asparagus lase moss, ginkgo, Wittania somunifera, Aerbarana terrestris, anteater, wasabi, Examples thereof include at least one selected from Nanban redwood, Justiacia adhatda, Blackonna, Thai carrot, and tamarind. These plants can be used alone or in combination of two or more. Roots, stems, leaves, fruits, seeds, bark, and the like are listed as plant use sites, and a plurality of sites may be mixed and used.
These plants include those originating in Japan, those originating in East Asia such as Thailand, Malaysia and Philippines, and those originating in South Asia such as India, Myanmar and Sri Lanka.
These plants are preferably used after being washed and dried before the extraction operation, or may be cut into an appropriate size for use.

The amount of the extraction medium to be used is generally in the range of 100 times to 1/20, and preferably 20 times to 1/10, based on the mass, with respect to the amount of the plant as the extraction raw material. More preferably, the amount is 10 times to 1/5, more preferably 10 times to 1/3.
As an extraction method, for example, an extraction medium is put in an unglazed pot of about 50 to 100 L, and a washed and dried plant is put therein. While maintaining the temperature at ℃, boil until moisture is lost; during that time, impurities such as ak can be removed every 3 days and the extracted medium may be replenished; finally the temperature is cooled to room temperature For example, the solid composition is separated by an operation such as filtration to remove the solid, and then the liquid composition is collected. The plant extract thus obtained is an opaque oily composition having a color such as greenish brown, greenish red, brown, brownish red, etc., depending on the plant used for extraction.

The specific combination of the plant and the extraction medium used for obtaining the oily extract of the plant used in the present invention and the prescription for the extraction are listed below.
Oily extract 1: Myrobalan fruit, Takamyrobalan fruit, and Ammacro fruit (extraction medium: sesame oil and milk).
Extraction prescription example:
Myrobalan fruit 1-15kg
Seitamirobaran fruit 1-15kg
Ammacro fruit 1-15kg
Sesame oil 5-35L
Milk 5-35L
This oily extract is particularly useful for lipolysis, cellulite prevention, migraine mitigation, sleep improvement, hair growth, and white hair prevention and control, etc., including hair, scalp, skin including body, especially neck, shoulder, back, It is desirable to apply to the waist, arms and shoulders.

Oily extract 2: Dorikos wing irata seed, snake cucumber root, and fern cordiphoria (extraction medium: sesame oil and milk).
Extraction prescription example:
Doriko Swing Irata Seeds 1-15kg
Snake root 1-20kg
Fern Cordyhoria 15-35kg
Sesame oil 15-45L
Milk 15-45L
This oily extract is particularly useful for relieving physical fatigue, stiff shoulders, low back pain, nervous system disorders, reducing joint pain, promoting blood circulation in the gums, protecting oral mucosa, and reducing stomatitis, including the scalp and body. Application to the skin and application to the oral cavity are desirable.

Oily extract 3: Anmarok fruit and Takasaburo (extraction medium: sesame oil and milk).
Extraction prescription example:
Amarok fruit 10-30kg
Takasaburo 30-50kg
Sesame oil 5-35L
Milk 25-55L
This oily extract is particularly useful for improving early gray hair, baldness, black glossy hair, and reducing headaches, and is preferably applied to the scalp and hair.

Oily extract 4: Ammarok fruit, Takasaburo and Nanbanai (extraction medium: coconut oil).
Extraction prescription example:
Amarok fruit 10-30kg
Takasaburo 10-30kg
Nambang Eye 10-30kg
Coconut oil 25-55L
This oily extract is particularly useful for reducing stress, headache, joint pain, preventing and suppressing dandruff, adjusting skin conditions, alleviating allergies, etc., and is preferably applied to the skin including the scalp, face and body.

Oily extract 5: Akane stalk (extraction medium: sesame oil, beeswax).
Extraction prescription example:
Akane stem 10-30kg
Sesame oil 45-75L
Beeswax 10-30kg
This oily extract is useful for improving dry skin, rough skin, scars, and sensitive skin, and is preferably applied to the skin including the face and body.

Oily extract 6: Fern cordiphoria, Sasahagi, Aerbaranata, eggplant root, Solanum virginianum, Amaranthus, Sorusayanoki root, Bengal Karatachi root, Asteraceae root, Stereosperms abeorens root, Premna ceratihoria root, Indoitebana, Melia azadiracta, Asparagus lacermosus root, Zinko stalk, and Witania somnifera root (extraction medium: sesame oil and milk).
Extraction prescription example:
1-10kg fern cordiphoria
Sasahagi 1-10kg
Aervaranata 1-10kg
Eggplant roots 1-10kg
Solanum Birginianum 1-10kg
Shrimp 1-10kg
1-10kg solitary tree root
Bengal Karatachi Root 1-10kg
1-10kg
Stereosperms Abeolence Root 1-10kg
Premunaserachihoria root 1-10kg
Indian Yaitbana 1-10kg
Melia Azajirakuta 1-10kg
Asparagus lacermos root 1-10kg
Ginkgo stem 1-10kg
Witania somnifera root 1-10kg
Sesame oil 5-35L
Milk 5-35L
This oily extract is useful for improving physical fitness, improving sleep, reducing high blood pressure, improving nervous system disorders, etc., and is preferably applied to the scalp and skin including the body.

Oily extract 7: Sasahagi, Aerbaranatamabishi, eggplant root, Solanum virginianum, Amaranthus prunus root, Bolivia roots, Astragalus root, Asteraceae root, Premna ceratihoria root, Asparagus race Moss root, Antarctic root, and Akane stalk (extraction medium: sesame oil and milk).
Extraction prescription example:
Sasahagi 1-15kg
Aervarana Tahamabishi 1-15kg
Eggplant roots 1-15kg
Solanum Birginianum 1-15kg
Shrimp 1-15kg
Soriyayanoki root 1-15kg
Bengal Karachi Root 1-15kg
1 to 15 kg
Stereosperms Abeolence root 1-15kg
Premunaserachihoria root 1-15kg
Asparagus racemosus root 1-15kg
Nankyo root 1-15kg
Akane stem 1-15kg
Sesame oil 5-35L
Milk 5-35L
This oily extract is useful for improving physical fitness, improving nervous system disorders, improving heart disease, reducing arthritis, promoting blood circulation of gums, protecting oral mucosa, reducing stomatitis, etc. And application to the oral cavity is desirable.

Oily extract 8: Wasabi tree bark, Japanese pearl oyster, Nanban redwood, Giustia adhatda, Black-eye root, Thai carrot, Sorilla root, and tamarind (Extraction medium: Sesame oil, Melia azalaci seed oil, castor oil, and milk fat ).
Extraction prescription example:
Wasabi tree bark 1-15kg
1 to 15 kg
Nanban Redwood 1-15kg
Justicia Adhatda 1-15kg
Crayona root 1-15kg
Thai carrots 1-15kg
Soriyayanoki root 1-15kg
Tamarind 1-15kg
Sesame oil 1-30L
Melia azadiracta seed oil 1-30L
Castor oil 1-30L
Milk fat 1-30L
This oily extract has an anti-inflammatory effect, and is useful for alleviating dermatitis, allergies, tonsillitis, rhinitis, etc., promoting blood circulation of gums, protecting oral mucosa, and reducing stomatitis. Application and application to the oral cavity are desirable.

In addition to oily extracts from plants as described above, a mixture of mustard oil (synapis oil) and camphor oil (camellia bark oil) is also useful for reducing severe muscle pain and pain. As an application to the skin containing the body. In addition, the mixing ratio of mustard oil (synapis oil) and camphor oil (camellia bark oil) is suitably in the range of 1:99 to 99: 1, preferably 80:20 to 99: 1. More preferably, it is in the range of 97: 3 to 98: 2.
The manufacturing method of mustard oil and camphor oil is not particularly limited.

The skin external preparation of this invention mix | blends an oily extract from the plant obtained as mentioned above as an active ingredient. Such an external preparation for skin is preferably formulated in a dosage form to be applied to the skin such as the scalp, hair, face and body.
The skin external preparation of the present invention is not particularly limited, and specifically includes a wide range of medicinal external preparations, medicinal cosmetics (quasi-drugs), ordinary cosmetics such as cosmetics, and toiletry products. Further, the external preparation for skin of the present invention can be in various forms, for example, lotion, cream, emulsion (milk lotion), pack, foundation, serum, cosmetic oil, ointment, gel, deodorant and deodorant, Hair nourishing tonics, hair creams, hair mists, hair gels, hair shampoos, hair rinses, face wash, body lotions, body creams, body soaps, cleansings, solid soaps and the like. Especially, the form of cleansing oil, milky lotion, and cream is preferable.
The blending amount of the oily extract from the plant in the external preparation for skin of the present invention is suitably 0.01 to 50% by mass, preferably 0.1 to 40% by mass, based on the total mass of the external skin preparation. Preferably it is 1-35 mass%.
The external preparation for skin of the present invention can be prepared according to a conventional method according to the desired dosage form, and an oily extract from a plant may be blended at an appropriate stage during the preparation process.

In formulating the external preparation for skin of the present invention, bases and additives can be appropriately used depending on the dosage form and form.
Examples of the base and additive used in the external preparation for skin of the present invention include animal and vegetable oils, fatty acids, wetting agents, thickeners, animal and plant extracts, amino acids, solvents, mineral oils, waxes, preservatives, and UV absorbers. , Sequestering agents, antioxidants, surfactants, pH adjusters, dyes / pigments, fragrances and the like, and can be blended within a range not impairing the effects of the present invention.
In formulating, it is desirable to use natural surfactants and emulsifiers in consideration of the stable dispersibility of oily extracts from plants. In addition, citrus essential oils such as orange oil and grapefruit oil, and herb essential oils such as lemongrass oil, rosemary oil, ginger oil, and patchouli oil are masked to mask the smell of sesame and palm oil, which are characteristic of oily extracts from plants. It is desirable to use it as an agent.
Specific examples of bases and additives are given below.

<Animal and vegetable oil>
Sasanqua oil, horse oil, vegetable squalane, squalane, olive oil (olive oil), camellia oil, wheat germ oil, jojoba oil, avocado oil, carrot oil (carrot oil), shea butter, palm oil, lanolins, egg yolk oil, Clove oil, rosehip oil, lavender oil, peppermint oil, spearmint oil, orange oil, grapefruit oil, lemongrass oil, rosemary oil, ginger oil, patchouli oil, almond oil (almond oil), cucumber oil, cucumber oil (candle) Nut oil), grape seed oil (grape oil), hardened castor oil (castor wax), sesame oil, rice germ oil (Oryza oil), rice bran oil (rice oil), safflower oil, soybean oil tea oil (tea seed oil, tea) Seed oil), evening primrose oil, corn germ oil (masola oil), rapeseed oil, persic oil (apricot kernel) , Peach seed oil), pearl oil, palm kernel oil, castor oil, sunflower oil (sunflower oil), zelkova oil, macadamia nut oil, meadowweed oil, owl, palm oil, peanut oil (peanut oil), orange luffy oil , Beef tallow, whale wax, powdered egg yolk oil (hydrogenated egg yolk oil), turtle oil (green turtle oil), mink oil, etc.

<Fatty acid>
Lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, isostearic acid, arachidonic acid isostearic acid, undecylenic acid, hard lanolin fatty acid, soft lanolin fatty acid, behenic acid, lauric acid, lanolin fatty acid and the like.
<Fat alcohol>
Lauryl alcohol, myristyl alcohol, cetostearyl alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, hexyl decanol, behenyl alcohol, octyldodecanol, lanolin alcohol, chimyl alcohol (glyceryl monocetyl ether), corelterol (costelin), sitosterol (sitosterin) , Hydrogenated lanolin alcohol, cetanol (cetyl alcohol palmityl alcohol), ceralkyl alcohol (monooleyl glyceryl ether), decyltetradecanol, batyl alcohol (glyceryl monostearyl ether), phytosterol (phytosterin), cottonseed oil and the like.

<Ester oil>
Glyceryl tricaprylate, cetyl 2-ethylhexanoate, glyceryl tri-2-ethylhexanoate, isocetyl octanoate, isononyl isononanoate, ethylene glycol dioctanoate, tri (caprylic / capric acid) glycerin, isopropyl myristate, isocetyl myristate, palmitic acid Cetyl acid, dialkylacetylated lanolin carbonate (lanolin acetate), isocetyl isostearate (hexyldecyl isostearate), cholesteryl isostearate, octyldodecyl erucate (EOD), cetyl octoate (cetyl 2-ethylhexanoate), cetate octanoate Stearyl (2-ethylhexanoate cetostearyl, isooctanoate cetostearyl), octyldodecyl oleate, decyl oleate, hexyl dimethyloctanoate Rudecyl, isocetyl stearate (hexyldecyl stearate), cholesteryl stearate, butyl stearate, long-chain α-hydroxy fatty acid cholesteryl (GL cholesteryl), glyceryl trimyristate, cetyl lactate, myristyl lactate, isopropyl palmitate (IPP, isopropyl Palmitate), hydroxystearate cholesterol, hexyldecanol, isotridecyl myristate (MITD), isoprovir myristate (1PM, isopropyl myristate), octyldodecyl myristate (MOD), myristyl myristate, hexyl laurate, lanolin fatty acid isopropyl, Lanolin fatty acid cholesteryl, diisostearyl malate, etc.

<Mineral oil>
Liquid paraffin, liquid isoparaffin, etc.
<Wax>
Microcrystalline wax, solid paraffin, beeswax, carnauba wax, reduced lanolin, adsorbed purified lanolin, hard lanolin, white beeswax (white wax), shellac, ceresin (earth wax), montan wax (montane wax), lanolin, lanolin derivatives and the like.

<Surfactant>
Lecithin (soybean or egg yolk) derivative, glycerin fatty acid ester, sorbitan fatty acid ester, alkyl sulfate, polyoxyethylene alkyl sulfosuccinate, alkylmethyl-β-alanine salt, soap base, fatty acid potassium, fatty acid sodium, sodium acylglutamate, acyl Triethanolamine glutamate, alkyldimethylamine oxide, alkylmethyl taurate, alkylaminopropionate, polyoxyethylene alkyl ether carboxylate, alkyl phosphate, alkyl glucoside, alkyltrimethylammonium chloride, alkyltrimethylammonium bromide, amidoamine , Dialkyldimethylammonium chloride, alkyldimethylacetic acid betaine, alkylamidopropylbetaine, alkylcarboxy Tylhydroxyethyl imidazolinium betaine, sorbitan isostearate, lanolin ethyl sulfate fatty acid aminopropylethyldimethylammonium (quaternium-33, cation LQ), distearyldimethylammonium chloride, stearyldimethylbenzylammonium chloride, stearyltrimethylammonium chloride, benzal chloride Luconium, benzethonium chloride, alkyldiaminoethylglycine hydrochloride, dimethicone copolyol, sucrose fatty acid ester, sucrose stearate ester, sorbitan sesquioleate, cetostearyl glucoside, multiple emulsion, tetradecene sulfonate, tetraoleate poly Oxyethylene sorbit (polyoxyethylene sorbitol tetraoleate), trioleic acid polio Xylethylenesorbitan, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, Nicolulus 41, propylene glycol fatty acid ester, bemulene,

Polyether modified silicon, sodium polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl ether phosphate, polyoxyethylene alkyl sulfate, polyoxyethylene alkyl phenyl ether phosphate, poly (oxyethylene oxypropylene) methyl polysiloxane Coalesced polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbit fatty acid ester, polyoxyethylene hydrogenated castor oil, polyethylene glycol fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene poly Oxypropylene alkyl ether, polyoxyethylene alkyl nonylphenyl ether, polyoxyethylene ether Kill ether phosphoric acid / phosphate, polyoxyethylene octyl phenyl ether, polyoxyethylene hydrogenated castor oil, polyoxyethylene stearyl ether, polyoxyethylene stearamide, polyoxyethylene cetyl ether, polyoxyethylene polyoxypropylene glycol, Polyoxyethylene sorbitan monooleate, ethylene glycol monostearate, glyceryl monostearate, sorbitan monostearate, propylene glycol monostearate, polyoxyethylene glyceryl monostearate, polyoxyethylene sorbitan monostearate, monopalmitic acid Polyoxyethylene sorbitan, polyethylene glycol monolaurate, polyoxyethylene sorbitan monolaurate, mono Uric acid polyoxyethylene sorbit, coconut oil fatty acid diethanolamide, coconut oil fatty acid methyl taurine sodium (N-cocoyl-N-methyl taurine sodium), lauroyl sarcosine salt, lauryl dimethylaminoacetic acid betaine, lauric acid diethanolamide, lauryl sulfate, Lauryl sulfate triethanolamine, lauric acid diethanolamide, lauroylmethyl β-alanine sodium solution, lauroylmethyltaurine sodium, lamellar structure emulsion and the like.

<Wetting agent>
Sodium hyaluronate, soybean fermented extract, hydroxyethyl chitosan, algae extract, water-soluble collagen, amacha extract, fennel extract, cuckoo extract, kiwi extract, cucumber extract, gardenia extract, chlorella extract, shea butter, ginger extract, garlic extract, bacmond extract , Loofah extract, button extract, poppy dandelion extract, budweed extract, grape leaf extract, yokoinin extract, mugwort extract, apple extract, saitai extract, hydrolyzed yeast extract, mucopolysaccharide, honey, hydrolyzed silk, sea salt, yogurt solution, Aloe vera extract-1, Carboxymethylchitin, Hydroxypropylchitosan, Trihalose, Polyglutamic acid, Peach leaf extract, Hypericum extract, Kawara mugwort extract, Raspberry extract, Rape fruit extract, orchid extract, lotus extract, okra extract, aloe vera juice powder, tannin, 1,3-butylene glycol, caprylyl glycol, 1,2-hexanediol, glycerin, diglycerin, isoprene glycol, polyethylene glycol, sorbit, Maltitol, trehalose, pentanediol, aquarizer EJ, ATP (adenosine triphosphate, adenosine triphosphate), atelocollagen, amino acid, γ-aminobutyric acid (piperidine acid), HS oil (HS lipid), NMF (white) Moisturizing factor), elastin, L-aspartic acid, sodium L-aspartate, L-arginine, L-isoleucine, L-glutamine, L-glutamic acid, sodium L-glutamate, L-threonine (L-threonine) ), L-tyrosine (L-tyrosine), L-tryptophan, L-valine, L-histidine hydrochloride, L-hydroxyproline (L-oxyproline), L-proline, L-leucine, L-methionine, magnesium chloride , Lysine hydrochloride (L-lysine salt number salt), nucleic acid

  Hydrolyzed elastin (elastin hydrolyzate), hydrolyzed keratin, hydrolyzed collagen solution, hydrolyzed collagen powder, hydrolyzed collagen ethyl, hydrolyzed collagen hexadecyl, hydrolyzed gelatin powder, soluble collagen (water-soluble collagen), xylit , Guanosine, guanine, glycine (aminoacetic acid), glucuronic acid, keratin, keratin amino acid, enzyme, collagen, collagen amino acid, collagen hydrolyzate (hydrolyzed collagen), mixed isomerized sugar (bentapiten), chondroitin sulfate sodium, saitai extract Liquid (Caitai extract), intercellular lipid, acidic mucopolysaccharide, cystine, cysteine, dipropylene glycol, plant complex enzyme, water-soluble elastin, sphingolipid (ceramide), gelatin, sericin, serine, large Lysophospholipid (lysolecithin), soy phospholipid (soy lecithin), DL-alanine, DL-bilolidon carponic acid (PCA), DL-pyrrolidone sodium carbonate (PCA soda), deoxylipoic acid (DNA), Tosaka extract (hydrolyzed Tosaka solution, Fipra N), lactic acid, sodium lactate (solution), uric acid, urea, phenylalanine, produ, egg yolk lecithin (egg yolk phospholipid), liponucleic acid (RNA), phosphate, riboflavin phosphate Sodium, phospholipid, lecithin, alphahydroxy acid (AHA), albumin (dried deglycated egg white), seawater dried product, hydrolyzed conchiolin solution (pearl protein drawing solution), hydrolyzed silk, hydrolyzed eggshell membrane (eggshell membrane keratin powder) , EM protein), casein, brown algae extract, dry yeast, sulfur-containing aluminum silicate Marine Clay), chitin, chitosan, bovine submandibular gland mucin, bovine thymus representation, bovine blood removal solution (Cernew), bovine spleen extract (revitalin), milk glycoprotein, glycolic acid, glucosamine (chitosamine) ), Serum albumin, yeast extract, conchiolin powder, mixed mucilage extract (multifruit, BSC), silk amino acid, silk drawing solution, silk powder, soy protein, soy protein hydrolyzate, skim milk powder, animal placenta Extract, trehalose, natto extract (fermented soybean fermented metabolite), bittern powder, lactic acid bacteria culture solution (natural SE solution), lactose (lactose), bipyzu bacteria extract (culture B, B), glucose (glucose), placenta extract (placenta) Drawing), propylene glycol, pullulan, whey (whey, lactic acid bacteria fermentation broth), marine Collagen, Mironaito-nekton (marine clay, sea of ooze), lactoferrin (Rakutokain), malic acid, royal jelly (Ochichi), royal jelly extract, and the like.

<Skin conditioning agent>
Raffinose <Thickener>
(Hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer, methylcellulose, ethylcellulose, carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxyvinyl polymer, polyvinyl alcohol, polyvinylpyrrolidone, cationized cellulose, cationized guar gum, sodium hyaluronate, poly Sodium acrylate, xanthan gum, carrageenan, polyacrylamide, hydrogenated polyisobutene, cetearyl alcohol, etc.

<Animal and plant extracts>
Placenta extract, marine placenta extract, hydrolyzed collagen, hydrolyzed keratin, hydrolyzed silk, hydrolyzed elastin, yeast extract, aloe extract, comfrey extract, peonies extract, perilla extract, assembly extract, hamamelis water, toad extract , Sage extract, Maronnier extract, Peach leaf extract, Yukinoshita extract, Melissa extract, Artemisia extract, Rosemary extract, Rice bran extract, Pine extract, Prune extract, etc.
<Amino acids>
L-alanine, L-arginine, L-aspartic acid, L-glutamine, L-cysteine, L-serine, L-tyrosine, L-proline, pyrrolidone carboxylate, glycine and the like.

<Solvent>
Purified water, normal water, weakly acidic water, ethanol, isopropanol, benzyl alcohol, etc.
<Vitamins>
Vitamin A, retinol acetate, pyridoxine hydrochloride, pyridoxine dicaprylate, biotin, nicotinic acid, nicotinamide, benzyl nicotinate, riboflavin, calcium pantothenate, D-pantothenyl alcohol, ascorbic acid, ascorbyl palmitate, L-ascorbyl phosphate Magnesium, ergocalciferol, vitamin E, tocopherol acetate, natural vitamin E, etc.

<Anti-inflammatory agent>
Dipotassium glycyrrhizinate, monoammonium glycyrrhizinate, allantoin, β-glycerretinic acid, diphenhydramine hydrochloride, sodium guaiazulene sulfonate, benzyl nicotinate, guaiazulene, lysozyme chloride, azulene, shikonin extract, cowslip (kivananoclin cherry), comfrey extract , Rice germ oil, Yokuinin extract (barley seed extract), aloe vera extract, loofah water, saxifrage extract, marshmallow (Usbenitachiaoi), perilla extract, aminocaproic acid, buckwheat extract, onionis extract, chamomile extract, licorice extract, clematis extract, cape Aloe extract, citrus extract, shikonin, linden extract, scallop extract, yarrow extract, thyme , Green tea extract, Japanese angelica root extract, witch hazel extract, parsley extract, grape leaf extract, button extract, horse chestnut extract, Melissa extract, cornflower extract, Roman chamomile extract, burnet extract, and the like.
<Preservative>
Methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, phenoxyethanol, bisabolol, hinokitiol, benzoic acid, sodium benzoate, salicylic acid, sodium salicylate, sorbic acid, potassium sorbate, undecylenic acid, pionein, lmenthol, d-camphor etc.

<Ultraviolet absorber>
Paraaminobenzoic acid, ethyl paraaminobenzoate, glyceryl paraaminobenzoate, 2-ethylhexyl paradimethylaminobenzoate, oxybenzone, dihydroxybenzophenone, dihydroxydimethoxybenzophenone, sodium dihydroxydimethoxybenzophenonesulfonate, sodium hydroxymethoxybenzophenonesulfonate, octyl salicylate and the like.
<Metal ion sequestering agent>
Edetic acid, edetate, trisodium ethylenediaminehydroxyethyl triacetate, diethylenetriaminepentaacetic acid, pentasodium diethylenetriaminepentaacetic acid, ethylenediaminetetrakis (2-hydroxyisopropyl) diolate, hydroxyethanedisulfonic acid, tetrasodium hydroxyethanedisulfonate, phytin Acid etc.
<Antioxidant>
Dibutylhydroxytoluene, butylhydroxyanisole, erythorbic acid, propyl gallate, octyl gallate, d-δ-tocopherol and the like.

The composition for oral cavity of this invention mix | blends an oil-based extract from the plant obtained as mentioned above. The composition for oral cavity referred to in the present invention can be made into various dosage forms such as a dentifrice, a mouthwash, and a form for massaging the gums. Specific forms of the oral composition include, for example, toothpastes, toothpastes, liquid dentifrices, moisturized dentifrices, liquid dentifrices, and other mouthwashes, mouthwashes, water toothpastes, mouth fresheners, and gargles. Tablet, ointment preparation, cream preparation, chewing gum and the like.
0.001-20 mass% is suitable with respect to the total mass of an oral composition, and, as for the compounding quantity of the oil-based extract from the plant in the composition for oral cavity of this invention, Preferably it is 0.01-10 mass%. More preferably, it is 0.05-5 mass%.

The oral composition of the present invention can be prepared according to a conventional method by blending appropriate bases and additives conventionally used according to various forms of the oral composition.
For example, the following bases and additives can be blended in a dentifrice such as a toothpaste.
Abrasive: Silica-based abrasive such as crystalline silica, amorphous silica, other silicic anhydride, hydrous silicic acid, aluminosilicate, aluminum oxide, aluminum hydroxide, insoluble sodium metaphosphate, insoluble potassium metaphosphate, titanium oxide, Dibasic calcium phosphate dihydrate, dibasic calcium phosphate anhydrate, heavy calcium carbonate, light calcium carbonate, calcium pyrophosphate and the like. The abrasive is generally used in an amount of 3 to 99% by mass.

  Binder: Carrageenan, carboxymethylcellulose, sodium carboxymethylcellulose, cellulose derivatives such as methylcellulose, hydroxymethylcellulose, sodium carboxymethylhydroxymethylcellulose, alkali metal alginate such as sodium alginate, propylene glycol alginate, xanthan gum, tragacanth gum, caraya gum, gum arabic, etc. Synthetic binders such as gums, polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, polyvinylpyrrolidone, and inorganic binders such as gelling silica, gelling aluminum silica, vegant and laponite. The binder is generally used in an amount of 0.5 to 10% by mass.

  Wetting agent: sorbit, glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylit, maltite, lactit, trehalose, neotrehalose, isotrehalose, α-maltosyl α, α-trehalose, etc. Carbohydrates containing carbohydrate derivatives of α and α trehalose. The wetting agent is generally used in an amount of 1 to 90% by mass.

  Surfactant: Sodium lauryl sulfate, sodium α-olefin sulfonate, sodium dodecylbenzene sulfonate, sodium lauryl sulfoacetate, sodium N-lauroyl sarcosine, N-acyl glutamate, sucrose fatty acid ester, polyoxyethylene hydrogenated castor Oils, polyoxyethylene polyoxypropylene block copolymers, alkylglycosides, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, alkyldimethylamine oxide, and the like. The surfactant is generally used in a blending amount of 0 to 5% by mass.

  pH adjuster: lactic acid, citric acid, glycolic acid, succinic acid, tartaric acid, malic acid and their salts, potassium carbonate, sodium bicarbonate, ammonium bicarbonate, potassium hydroxide, sodium hydroxide, monoethanolamine, triethanolamine 2-amino-2-methyl-propanediol, arginine, lysine, etc., or a mixture thereof. The pH adjuster is generally used in an amount of 0 to 10% by mass.

Further optional sweeteners such as sodium saccharin, stevioside, glycyrrhizin, perilartin, thaumatin, aspartylphenylalanine methyl ester, p-methoxycinamic aldehyde, sucrose, fructose, sodium cyclamate; spearmint oil, peppermint oil, wintergreen oil Fragrances such as sassafras oil, clove oil, eucalyptus oil, sage oil, mayonnaise oil, thyme oil, lemon oil, orange oil, l-menthol, carvone, anethole, eugenol, thymol, methyl salicylate; benzoic acid, sodium benzoate, Preservatives such as p-hydroxypropyl benzoic acid, p-hydroxybutyl benzoic acid, lower fatty acid monoglyceride, paraben; quaternary ammonium salt, triclosa , Alkyldiaminoethylglycine hydrochloride, cetylpyridinium chloride, decalinium chloride, benzethonium chloride and other fungicides; enzymes such as ε-aminocaproic acid, dextranase, amylase, protease, mutanase, lytic enzyme, lysozyme; sodium monofluorophosphate , Fluorides such as potassium monofluorophosphate, sodium fluoride, ammonium fluoride, stannous fluoride; chlorhexidine salts, dihydrocholesterol, glycyrrhetin salts, glycyrrhetinic acid, chlorophyll, caropeptide, tocopherol acetate, azulene, lysozyme chloride, zeolite And anticalculus agents such as polyphosphoric acid, anti-plaque agents, potassium nitrate, aluminum lactate and the like can be added.
Furthermore, since the oily extract from a plant has a peculiar taste, a taste-masking effect can be exhibited by adding powders such as cinnamon, neem and cloves to the oral composition.
In addition, the addition amount of these arbitrary components can be made into a normal amount in the range which cannot prevent the effect of this invention.

EXAMPLES Hereinafter, although a test example and an Example are given and this invention is demonstrated in more detail, this invention is not limited to these.
[Test 1]
Cleansing oil 1, milky lotion 1 and cream 1 were prepared according to the following formulation.
<Example 1>
Cleansing oil 1 (for dry and sensitive skin)
Component composition (unit: mass%)
1. Southern oil 44.8875
2. Squalane 41.3
3. Polysorbate 85 8.55
4. Sorbitan sesquioleate 1.3
5. Oily extract from plants 3.0
(Extraction formula: Anmarok fruit: 20 parts by weight, Takasaburo: 20 parts by weight,
Nambang Eye: 20 parts by weight, palm oil: 40 parts by weight)
6. Water 0.45
7. Tocopherol 0.2125
8. Orange oil 0.2
9. Patchouli oil 0.1
Preparation procedure: 1.2.5.7. Was mixed and stirred. After 3.4.6. Was added, 8.9. Was added.

<Example 2>
Milky lotion 1 (for dry and sensitive skin)
Component composition (unit: mass%)
1. Water 88.915
2. Hyaluronic acid Na 3
3. Squalane 2
4. 1,2-hexanediol 1.5
5. Oily extract from plants 3.0
(Extraction formula: Anmarok fruit: 20 parts by weight, Takasaburo: 20 parts by weight,
Nambang Eye: 20 parts by weight, palm oil: 40 parts by weight)
6. Polyacrylamide 0.3
7. Hydrogenated polyisobutene 0.225
8. Mineral oil 0.225
9. Polysorbade 85 0.135
10. Glycyrrhizic acid 2K 0.1
11. Caprylyl glycol 0.3
12. Orange oil 0.2
13. Patchouli oil 0.1
Preparation procedure: After gradually adding 1.2.4.10. To 3.5.6.7.8.9.11., 12.13. Was added.

<Example 3>
Face cream 1 (for dry and sensitive skin)
Component composition (unit: mass%)
1. Water 66.9
2. Squalane 12.255
3. Glycerin 5
4. Cetearyl alcohol 4
5. Hyaluronic acid Na 3
6. Raffinose 2
7. 1,2-Hexanediol 1.5
8. Oily extract from plants 3.0
(Extraction formula: Anmarok fruit: 20 parts by weight, Takasaburo: 20 parts by weight,
Nambang Eye: 20 parts by weight, palm oil: 40 parts by weight)
9. Cetearyl glucoside 1.0
10. Caprylyl glycol 0.5
11. (Hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer
0.375
12. Allantoin 0.1
13. Polysorbate 60 0.055
14. Sorbitan isostearate 0.015
15. Orange oil 0.2
16. Patchouli oil 0.1
Preparation procedure: A (1.3.5.6.7.12.) Was heated and stirred to 80 ° C, B (2.4.8.9.10.11.13.14.) Was heated and stirred to 80 ° C, B was added to A, and the mixture was stirred and cooled to 40 ° C. When it was, I put 15.16.

Using five persons (female) as subjects, each person used three types of cleansing oil 1, milky lotion 1 and face cream 1 for a predetermined period of time to perform sensory evaluation. Table 1 shows the information, period of use, and general evaluation of the five people.
Answers to various questions about cleansing oil 1, milky lotion 1 and face cream 1 are as follows. Each evaluation number represents the number of people.

Cleansing oil 1

Milky lotion 1

Face cream 1

全体の質問に対して、「とても良い」、及び次の評価である「より良い」と答えた人を合わせると、すなわち、肌質の改善を実感した人は９４．５％に達した。上記の結果から、所定の植物からの油性エキスを含めた化粧料が肌をいためずに、汚れを落とし、肌のコンディションを改善し、保湿を与えながら、肌質が改善できたことが判った。

The total number of people who answered “very good” and “better” as the next evaluation for all questions, that is, 94.5% of the people who realized improvement in skin quality. From the above results, it was found that the cosmetics including the oily extract from a given plant could improve the skin quality while removing dirt, improving the condition of the skin, and moisturizing without damaging the skin. .

[Test 2]
Cleansing oil 2, milky lotion 2 and face cream 2 were prepared according to the following formulation.
<Example 4>
Cleansing oil 2 (for moisturizing and normal skin)
Component composition (unit: mass%)
1. Southern oil 44.9
2. Squalane 41.3
3. Polysorbate 85 8.5
4. Oily extract from plants 3.0
(Extraction formula: Akane stalk: 20 parts by weight, sesame oil: 60 parts by weight, beeswax: 20 parts by weight)
5. Sorbitan sesquioleate 1.3
6. Water 0.5
7. Tocopherol 0.2
8. Orange oil 0.1
9. Patchouli oil 0.2
Preparation procedure: 1.2.4.7. Was mixed and stirred. After adding 3.5.6., 8.9. Was added.

<Example 5>
Milky Lotion 2 (for moisturizing and normal skin)
Component composition (unit: mass%)
1. Water 88.915
2. Hyaluronic acid Na 3
3. Squalane 2
4. Oily extract from plants 3.0
(Extraction formula: Akane stalk: 20 parts by weight, sesame oil: 60 parts by weight, beeswax: 20 parts by weight)
5. 1,2-hexanediol 1.5
6. Polyacrylamide 0.3
7. Caprylyl glycol 0.3
8. Hydrogenated polyisobutene 0.225
9. Mineral oil 0.225
10. Polysorbate 85 0.135
11. Glycyrrhizic acid 2K 0.1
12. Orange oil 0.2
13. Patchouli oil 0.1
Preparation procedure: After gradually adding 1.2.5.11. To 3.4.6.-10., 12.13. Was added.

<Example 6>
Face cream 2 (for moisturizing and normal skin)
Component composition (unit: mass%)
1. Water 66.7995
2. Squalane 12.55
3. Glycerin 5
4. Cetearyl alcohol 4
5. Hyaluronic acid Na 3
6. Raffinose 2
7. Oily extract from plants 3.0
(Extraction formula: Akane stalk: 20 parts by weight, sesame oil: 60 parts by weight, beeswax: 20 parts by weight)
8. 1,2-hexanediol 1.5
9. Cetearyl glucoside 1.0
10. Caprylyl glycol 0.5
11. (Hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer
0.375
12. Allantoin 0.1
13. Polysorbate 60 0.055
14. PCA-Na 0.05
15. BG 0.05
16. Sorbitan isostearate 0.015
17. Rosemary extract 0.0001
18. Lemon extract 0.0001
19. Scots pine cone extract 0.0001
20. Hop Extract 0.0001
21. Horsetail extract 0.0001
22. Orange oil 0.2
23. Patchouli oil 0.1
Preparation procedure: A (1.3.5.6.8.) Was heated and stirred to 80 ° C, while B (2.4.7.9. 10.11.12.13.14.15.16.) Was heated and stirred to 80 ° C, and B was added to A and stirred. After cooling, when the temperature reached 40 ° C., 17.-23.

Using five persons (female) as subjects, each person used three types of cleansing oil 2, milky lotion 2 and face cream 2 for a predetermined period of time to perform sensory evaluation. Table 2 shows the information, period of use, and general reviews of the five people.
The answers to various questions about cleansing oil 2, milky lotion 2 and face cream 2 are as follows. Each evaluation number represents the number of people.

Cleansing oil 2

Milky Lotion 2

Face cream 2

全体の質問に対して、「とても良い」、及び次の評価である「より良い」と答えた人を合わせると、すなわち、肌質の改善を実感した人は９１％に達した。上記の結果から、所定の植物からの油性エキスを用いた化粧料が、荒れた皮膚のよごれをとりつつ、肌に潤いを与え、結果として明るくきめのある肌に改善することが判った。使用期間１週間でも肌の保湿力をひきだし、はりを出すことが判った。

The total number of people who answered “very good” and the next evaluation “better” to the overall question, that is, 91% of the people who realized an improvement in skin quality. From the above results, it was found that cosmetics using an oily extract from a predetermined plant moisturize the skin while removing dirt on the rough skin, and as a result, improve the skin to be bright and textured. It was found that the skin moisturizing power was pulled out even during the use period of one week, and a beam was produced.

[Test 3]
<Example 7>
Body cream 1 was prepared according to the following formulation.
Body cream 1
Component composition (unit: mass%)
1. Water 72.2
2. Squalane 10.51
3. Glycerin 5
4. Cetearyl alcohol 3.2
5. Raffinose 2
6. Mixture of mustard oil and camphor oil (mass ratio 97.5: 2.5)
3.0
7. 1,2-Hexanediol 1.5
8. Cetearyl glucoside 0.8
9. (Hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer
0.75
10. Caprylyl glycol 0.5
11. Polysorbate 60 0.11
12. Allantoin 0.1
13. Sorbitan isostearate 0.03
14. Lemongrass oil 0.1
15. Rosemary oil 0.1
16. Ginger root oil 0.1
Preparation procedure: A (1.3.5.7.12.) Is heated and stirred to 80 ° C., B (2.4.6.8.9.10.11.13) is heated and stirred to 80 ° C., B is added to A, and the mixture is stirred and cooled to 40 ° C. I put 14.15.16.

The body cream 1 was used for a predetermined period with 8 subjects as subjects, and a sensory evaluation was performed. Table 3 shows the information, period of use, and general evaluation of 8 people.
Answers to various questions are as follows. Each evaluation number represents the number of people.

上記の試験の被験者において何らかの改善効果を実感した割合が84％に達し、所定の植物からのオイルを含めたボディークリームが肩こり、腰痛、神経痛、関節痛の改善及び治癒効果、筋肉痛の緩和及び改善効果を発揮することが判った。

The percentage of subjects who experienced some improvement effect in the above-mentioned test reached 84%, and body cream including oil from a given plant had stiff shoulders, low back pain, neuralgia, joint pain improvement and healing effect, muscle pain relief and It was found that the improvement effect was demonstrated.

[Test 4]
<Example 8>
Body cream 2 was prepared according to the following formulation.
Body cream 2
Component composition (unit: mass%)
1. Water 71.71
2. Squalane 10.51
3. Glycerin 5
4. Cetearyl alcohol 3.2
5. Raffinose 2.0
6. 1,2-hexanediol 1.5
7. Oily extract from plants 3.0
(Extraction formula: Myrobalan fruit: 10 parts by weight, Seitakamirobaran fruit: 10 parts by weight,
Ammacro fruit: 10 parts by weight, sesame oil: 35 parts by weight, milk: 35 parts by weight)
8. Cetearyl glucoside 0.8
9. (Hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer
0.75
10. Caprylyl glycol 0.5
11. Polysorbate 60 0.11
12. Allantoin 0.1
13. Sorbitan isostearate 0.03
14. Grapefruit peel oil 0.53
15. Orange oil 0.13
16. Pepper fruit oil 0.13
Preparation procedure: A (1.3.5.6.12.) Is heated and stirred to 80 ° C, B (2.4.7.8.9.10.11.13.) Is heated and stirred to 80 ° C, B is added to A, and the mixture is cooled to 40 ° C after stirring and cooling. When it was, I put 14.15.16.

The body cream 2 was used for a predetermined period with 7 persons (women) as subjects, and sensory evaluation was performed. Table 4 shows the information, period of use, and general reviews of the seven people.
Answers to various questions are as follows. Each evaluation number represents the number of people.

  In the above test, 51% of the subjects clearly felt the improvement of the skin condition at the place of use, and when combined with the subjects who answered that they felt the effect, 86% of the subjects felt the effect in an average of two and a half weeks I understood.

[Test 5]
<Example 9>
A toothpaste was prepared according to the following formulation.
Component composition (unit: mass%)
1. Calcium carbonate 32.5
2. Water 27.4
3.Sorbit liquid 20.0
4. Glycerin 10.0
5. Silicic anhydride 5.0
6. Oily extract from plants 3.0
(Extraction formula: Doricos wing irata seeds: 10 parts by weight, Snake cucumber roots: 10 parts by weight,
Fern cordiphoria: 20 parts by weight, sesame oil: 30 parts by weight, milk: 30 parts by weight)
7. Carboxymethylcellulose Na 1.2
8. Ethanol 0.5
9. Mentha oil 0.2
10. Dipotassium glycyrrhetinate 0.05
11. Cinnamon powder 0.05
12. Globe end 0.05
13. End of Neem 0.05
Manufacturing process: In a vacuum emulsification pot (mixing mixer), 1, 2, 3, 4, 5, and 10 are mixed with stirring with a propeller, uniformly dispersed, added with 7 and 4, and then mixed with 8, 9 , 6, 11, 12, 13 were added and mixed, defoamed and stirred to finish.

The above-mentioned toothpaste was used for 10 persons as subjects and subjected to sensory evaluation. Table 5 shows the information of 10 people, the method of use, the period of use, and the general comment.
Answers to various questions are as follows. Each evaluation number represents the number of people.

本発明の口腔用組成物により、歯茎の炎症を顕著に改善することができ、炎症を抑えるだけでなく、歯茎を健康に保ち、保護することができるとわかった。

It has been found that the oral cavity composition of the present invention can remarkably improve the inflammation of the gums and not only suppress the inflammation but also keep the gums healthy and protected.

[Test 6]
<Example 10>
A gel dentifrice was prepared according to the following formulation.
Component composition (unit: mass%)
1. Purified water 42.95
2. Sorbit solution 20.0
3. Glycerin 10.0
4. Silicic anhydride 5.0
5. Oily extract from plants 3.0
(Formulation of extraction: Sasahagi: 5 parts by weight, Aerbarana tahamabishi: 5 parts by weight, eggplant root: 5 parts by weight, Solanum virginianum: 5 parts by weight, Amaranthus: 5 parts by weight, Sorazayanoki root: 5 parts by weight, Bengal Karatachi Root: 5 parts by weight, Yellow-bellied Agaric: 5 parts by weight, Stereosperm Aveolence Root: 5 parts by weight, Premunacera root, 5 parts by weight, Asparagus racemosus root: 5 parts by weight, Nankyo (Root: 5 parts by weight, Akane stalk: 5 parts by weight, Sesame oil: 17.5 parts by weight, Milk: 17.5 parts by weight)
6. Ethanol 15.0
7. Xylitol 0.5
8. Carboxymethylcellulose Na 3.0
9. Polyethylene glycol 400 0.3
10. Dipotassium glycyrrhetinate 0.05
11. l-Menthol 0.05
12. Cinnamon powder 0.05
13. Globe end 0.05
14. End of Neem 0.05
Manufacturing process: 1, 2, 3, 4, 7, 9, 10 in a vacuum emulsification pot (mixing mixer) while stirring with a propeller, mix uniformly, add 8, 3 and then mix 11, 6, 5, 12, 13, and 14 were added and mixed, and after defoaming and stirring, the mixture was finished.

The gel dentifrice was used for 8 periods as subjects, and sensory evaluation was performed. Table 6 shows the information of 8 people, the method of use, the period of use, and the general evaluation.
Answers to various questions are as follows. Each evaluation number represents the number of people.

上記結果から、歯茎の炎症を抑え、保護し、歯茎を引き締める効果があることが判った。

From the above results, it was found that there is an effect of suppressing and protecting gum inflammation and tightening the gum.

[Test 7]
<Example 11>
Water polish was prepared according to the following formulation.
Component composition (unit: mass%)
1. Water 51.55
2. Oily extract from plants 5.0
(Extraction formula: Wasabi tree bark: 5 parts by weight, Japanese tiger beetle: 5 parts by weight, Nanban redwood: 5 parts by weight, Justiacia adhata: 5 parts by weight, Crayona root: 5 parts by weight, Thai carrot box: 5 parts by weight , Soraya tree root: 5 parts by weight, Tamarind: 5 parts by weight, Sesame oil: 15 parts by weight, Melia azadiracta seed oil: 15 parts by weight, Castor oil: 15 parts by weight, Milk fat: 15 parts by weight)
3. Dipotassium glycyrrhizinate 0.2
4. Glycerin 20.0
5. Ethanol 20.0
6. Xanthan gum 3.0
7. Carrageenan 0.1
8. Cinnamon powder 0.05
9. Globe end 0.05
10. Neem end 0.05
Production process: In a vacuum emulsifier (mixing mixer), mix 4, 7, and 6 with stirring with a propeller, uniformly disperse, add 3 and mix, then add 1 and mix and disperse Gelled, depressurized, degassed, stirred, added with 5, 2, 8, 9, 10 and mixed, finished by defoaming and stirring.

With 8 subjects as subjects, the above water polish was used for a predetermined period of time to perform sensory evaluation. Table 7 shows the information of 8 people, the method of use, the period of use, and the overall review.
Answers to various questions are as follows. Each evaluation number represents the number of people.

上記の結果より、炎症が出ずらくなり、歯茎の健康状態が向上し、被験者のすべてで満足の得られる結果が得られたことが判る。

From the above results, it can be seen that inflammation was difficult to occur, the health condition of the gums was improved, and satisfactory results were obtained for all the subjects.

[Test 8]
<Example 12>
A mouthwash was prepared according to the following formulation.
Component composition (unit: mass%)
1. Water 94.33
2. Oily extract from plants 0.05
(Extraction formula: Doricos wing irata seeds: 10 parts by weight, snake cucumber roots: 10 parts by weight, fern cordiphoria: 20 parts by weight, sesame oil: 30 parts by weight, milk: 30 parts by weight)
3. Ethanol 3.0
4. Chaex 2.0
5. Sodium benzoate 0.2
6. Citric acid 0.13
7. Xylitol 0.1
8. Cinnamon powder 0.05
9. Globe end 0.05
10. Neem end 0.05
11. l-Menthol 0.02
12. Na citrate 0.02
Manufacturing process: In a vacuum emulsification pot (mixing mixer), mix 1, 4, 5, 6, 7, 12 while stirring with a propeller, uniformly disperse, add 3, 2, 8, 9, 10 Mix and disperse, add 11 and mix, defoam and finish after stirring.

The above mouthwash was used for a predetermined period of time for 7 subjects, and sensory evaluation was performed. Table 8 shows the information of the seven people, the method of use, the period of use, and the overall review.
Answers to various questions are as follows. Each evaluation number represents the number of people.

口内炎、炎症、腫れのすべてにおいて、改善が見られ、歯茎が引き締まってよい結果が得られた。

Stomatitis, inflammation and swelling were all improved, and the gums were tightened with good results.

Claims (5)

  A skin external preparation containing an oily extract obtained from a plant using at least one selected from the group consisting of sesame oil, milk, coconut oil, beeswax, melia azadiracta seed oil, castor oil and milk fat as an extraction medium.   The skin external preparation according to claim 1, wherein the skin external preparation is a cosmetic.   Plants are Myrobalan, Seycamylobaran, Ammacro, Doricos wing irata, Snail cucumber, Fern cordiphoria, Takasaburo, Nambanai, Akane, Sasahagi, Aerbaranata, Eggplant, Solanum virginianum, Hamabishi, Sorizayanoki, Bengal Karatachi, Azalea Spermmus Abeolence, Premna Serachihoria, Indian Yaitbana, Melia Azadiracta, Asparagus Lasemosus, Ginkgo, Witania somunifera, Aerbara natahabishi, nanyousou, wasabi, okaban bay, nanban azuki, jusuchi The skin external preparation of Claim 1 or 2 which is at least 1 sort (s) chosen from the group which consists of a sheaad hatoda, kuroyona, taiwan carrot, and tamarind.   An oral composition comprising an oily extract obtained from a plant using at least one of sesame oil, milk, coconut oil, beeswax, melia azadiracta seed oil, castor oil and milk fat as an extraction medium.   Plants are Myrobalan, Seycamylobaran, Ammacro, Doricos wing irata, Snail cucumber, Fern cordiphoria, Takasaburo, Nambanai, Akane, Sasahagi, Aerbaranata, Eggplant, Solanum virginianum, Hamabishi, Sorizayanoki, Bengal Karatachi, Azalea Spermmus Abeolence, Premna Serachihoria, Indian Yaitbana, Melia Azadiracta, Asparagus Lasemosus, Ginkgo, Witania somunifera, Aerbara natahabishi, nanyousou, wasabi, okaban bay, nanban azuki, jusuchi The composition for oral cavity of Claim 4 which is at least 1 sort (s) chosen from the group which consists of a shear ad hatoda, kuroyona, taiwan carrot, and tamarind.