JP2009063448A - Automatic analyzer - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an automatic analyzer having a constitution suitable for miniaturization. <P>SOLUTION: This analyzer includes a specimen nozzle for discharging/sucking a specimen; a specimen dispensation mechanism having one end of the specimen nozzle mounted thereon, rotatable with respect to an axis in parallel with the longitudinal direction of the mounted specimen nozzle, and having specimen nozzle transfer means for transferring the specimen nozzle; a reagent nozzle for discharging/sucking a reagent; and a reagent dispensation mechanism having one end of the reagent nozzle mounted thereon, rotatable independently of the specimen nozzle transfer means, with respect to an axis in parallel with the longitudinal direction of the mounted reagent nozzle which is an axis agreeing with the rotation axis carried by the specimen nozzle transfer means, and having reagent nozzle transfer means for transferring the reagent nozzle. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an automatic analyzer that analyzes a component of a specimen by reacting a specimen with a reagent and optically measuring the result of the reaction.

  Conventionally, in an automatic analyzer that analyzes a sample component by reacting a sample with a reagent and optically measuring the result of the reaction, a plurality of reaction vessels are arranged side by side on the circumference. There are provided a sample dispensing mechanism and a reagent dispensing mechanism for dispensing a sample and a reagent respectively at predetermined positions (see, for example, Patent Document 1).

Japanese Patent No. 3436095

  However, in the conventional automatic analyzer described above, the sample dispensing mechanism and the reagent dispensing mechanism are provided separately, which is an obstacle to downsizing the apparatus.

  The present invention has been made in view of the above, and an object of the present invention is to provide an automatic analyzer having a configuration suitable for miniaturization.

  In order to solve the above-described problems and achieve the object, an automatic analyzer according to the present invention reacts a sample with a reagent and analyzes the components of the sample by optically measuring the result of the reaction. An automatic analyzer, wherein a sample nozzle for discharging or aspirating a sample and one end of the sample nozzle are attached, and the sample nozzle is rotatable with respect to an axis parallel to the longitudinal direction of the attached sample nozzle. A sample dispensing mechanism having a sample nozzle transfer means for transferring, a reagent nozzle for discharging or aspirating a reagent, and one end of the reagent nozzle, and an axis parallel to the longitudinal direction of the attached reagent nozzle, Reagent nozzle transfer means for transferring the reagent nozzle, which is rotatable independently of the sample nozzle transfer means with respect to an axis coinciding with the rotation axis of the sample nozzle transfer means Characterized by comprising a reagent dispensing mechanism having.

  In the automatic analyzer according to the present invention as set forth in the invention described above, the sample nozzle transfer means includes a plurality of sample dispensing arms including a sample nozzle mounting arm to which the sample nozzle is mounted, and the sample dispensing adjacent to each other. A plurality of sample dispensing arm coupling portions for rotatably coupling the arms, and the reagent nozzle transfer means is adjacent to a plurality of reagent dispensing arms including a reagent nozzle mounting arm for mounting the reagent nozzle. And a plurality of reagent dispensing arm coupling portions that rotatably couple the reagent dispensing arms.

  Moreover, the automatic analyzer according to the present invention is characterized in that, in the above invention, the sample nozzle transfer means and the reagent nozzle transfer means are interlocked in a direction parallel to the rotation axis.

  The automatic analyzer according to the present invention is characterized in that, in the above-mentioned invention, the height of the tip of the sample nozzle and the height of the tip of the reagent nozzle are substantially the same.

  In the automatic analyzer according to the present invention, in the above invention, even if the tip of the sample nozzle reaches the lowest point, it does not come into contact with other members, and at least the reagent dispensing mechanism performs a reagent aspirating operation. A specimen nozzle retracting area that is an area where the specimen nozzle is retracted, and an area that does not come into contact with other members even when the tip of the reagent nozzle reaches the lowest point, and at least the specimen dispensing mechanism A reagent nozzle retracting area, which is an area in which the reagent nozzle is retracted during the sample aspirating operation, is further provided.

  In the automatic analyzer according to the present invention, in the above invention, when the reagent dispensing mechanism cleans the reaction container that causes the sample and the reagent to react, the reagent dispensing mechanism first distributes the reaction container to the reaction container in the analysis step after the cleaning. The reagent to be poured is discharged as a washing liquid into the reaction vessel.

  According to the present invention, a sample nozzle having a sample nozzle for discharging or aspirating a sample, and a sample nozzle transfer means attached to one end of the sample nozzle and rotatable with respect to an axis parallel to the longitudinal direction of the attached sample nozzle. The injection mechanism, the reagent nozzle for discharging or aspirating the reagent, and one end of the reagent nozzle are attached, and the axis parallel to the longitudinal direction of the attached reagent nozzle and corresponding to the rotation axis of the specimen nozzle transfer means A reagent dispensing mechanism that can rotate independently of the sample nozzle transporting means and has a reagent nozzle transporting means for transporting the reagent nozzle, so that the sample dispensing mechanism and the reagent dispensing mechanism are provided separately. Space can be saved compared to the above, and downsizing of the apparatus can be realized.

  The best mode for carrying out the present invention (hereinafter referred to as “embodiment”) will be described below with reference to the accompanying drawings. Note that the drawings referred to in the following description are merely schematic, and when the same object is shown in different drawings, dimensions, scales, and the like may be different.

  FIG. 1 is a diagram showing a configuration of an automatic analyzer according to an embodiment of the present invention. The automatic analyzer 1 shown in FIG. 1 dispenses a specimen (sample) such as blood or body fluid and a reagent according to a test item of the specimen into a predetermined reaction container, and converts the reaction liquid in the reaction container. A measurement unit 101 that performs optical measurement, and a data processing unit 201 that controls the automatic analyzer 1 including the measurement unit 101 and analyzes a measurement result in the measurement unit 101, and these two units Is a device that automatically and continuously performs biochemical analysis of a plurality of specimens by cooperating with each other. The “liquid” here includes a liquid containing a small amount of a solid component.

  The measurement unit 101 includes a specimen container holder 11 that holds a specimen container 41 that contains a specimen, a reagent container holder 12 that holds a plurality of reagent containers 43 that contain reagents, and a reaction container 44 that reacts the specimen and the reagent. The reaction container holder 13 to be held, the dispensing device 14 for dispensing the specimen and the reagent to the reaction container 44, the stirring unit 15 for stirring the liquid inside the reaction container 44, and the reaction container 44 are irradiated with light, The photometric unit 16 for optically measuring the light transmitted through the reaction vessel 44 out of the irradiated light, and the reaction vessel cleaning for washing the reaction vessel 44 on the reaction vessel holder 13 using a cleaning liquid made of ion exchange water or the like. Unit 17.

  The sample container holder 11 holds a plurality of racks 42 that hold a plurality of sample containers 41 arranged in a line along the longitudinal direction along the short direction of the rack 42 orthogonal to the longitudinal direction.

  The reagent container holder 12 holds a plurality of reagent containers 43 arranged in a matrix. The interior of the reagent container holder 12 is set to a temperature lower than room temperature in order to suppress reagent deterioration and denaturation.

  The sample container holder 11 and the reagent container holder 12 do not have a mechanism for transferring the rack 42 and the reagent container 43, respectively, and hold the sample container 41 and the reagent container 43 in a stationary state.

  The reaction vessel holder 13 has a plurality of reaction vessels 44 arranged side by side along the circumference. The reaction vessel holder 13 can be rotated in the circumferential direction in which the reaction vessels 44 are arranged side by side, and the temperature inside thereof is kept constant at about 37 ° C.

  FIG. 2 is a diagram illustrating a configuration of a main part of the dispensing device 14. The dispensing device 14 is accommodated in the sample dispensing mechanism 18 that dispenses the sample accommodated in the sample container 41 held by the sample container holder 11 into the reaction container 44 and the reagent container 43 held by the reagent container holder 12. A reagent dispensing mechanism 19 for dispensing the reagent into the reaction container 44;

  The sample dispensing mechanism 18 includes a thin tubular sample nozzle 18n that sucks and discharges a sample contained in the sample container 41, a sample nozzle mounting arm 501 that attaches the end of the sample nozzle 18n to the tip, and a sample nozzle mounting arm. A proximal end arm 502 positioned on the proximal end side of 501; an arm connecting portion 503 that rotatably connects the sample nozzle mounting arm 501 to the proximal end arm 502; and a proximal end portion of the proximal end arm 502. The supporting portion 504 to be supported, the arm driving portion 505 for rotating the proximal end side arm 502 by moving the supporting portion 504 up and down and rotating around the axis O1, and the rotation of the arm connecting portion 503 around the axis O2 And an arm driving unit 506 that rotates the sample nozzle mounting arm 501 with respect to the base end side arm 502 by performing the operation. The arm driving units 505 and 506 are driven under the control of the control unit 34 included in the data processing unit 201.

  The reagent dispensing mechanism 19 has the same configuration as the sample dispensing mechanism 18. That is, the reagent dispensing mechanism 19 includes a thin tubular reagent nozzle 19n that sucks and discharges the reagent contained in the reagent container 43, a reagent nozzle mounting arm 601 that attaches the end of the reagent nozzle 19n to the tip, and a reagent nozzle A proximal end arm 602 positioned on the proximal end side of the mounting arm 601, an arm connecting portion 603 that rotatably connects the reagent nozzle mounting arm 601 to the proximal end arm 602, and a proximal end of the proximal end arm 602 A support portion 604 that supports the arm portion, an arm drive portion 605 that drives the proximal-side arm 602 to rotate by raising and lowering the support portion 604 and rotating around the axis O1, and around the axis O3 of the arm connecting portion 603 An arm driving unit 606 that rotates the reagent nozzle mounting arm 601 with respect to the proximal-side arm 602 by performing rotation. The support unit 604 is interlocked with the support unit 504 of the sample dispensing mechanism 18 in the vertical direction, but the rotation around the axis O1 can be performed independently of the support unit 504. The arm driving units 605 and 606 are driven under the control of the control unit 34 included in the data processing unit 201.

  The height of the tip of the reagent nozzle 19n is substantially the same as the height of the tip of the sample nozzle 18n. In other words, the length of the reagent nozzle 19n is different from the length of the sample nozzle 18n.

  The measurement unit 101 is provided with a sample nozzle cleaning unit 20 for cleaning the sample nozzle 18n and a reagent nozzle cleaning unit 21 for cleaning the reagent nozzle 19n.

  FIG. 3 is a diagram schematically showing a more detailed configuration of the specimen dispensing mechanism 18. Connected to the upper end of the sample nozzle 18n is a tubular tube 507 serving as a flow path for the cleaning liquid Lq that transmits pressure to the tip (lower end) of the sample nozzle 18n during suction or discharge. The other end of the tube 507 is connected to a syringe 508 that generates a pressure that is transmitted via the cleaning liquid Lq during suction or discharge. The syringe 508 includes a cylinder 508a and a piston 508b, and the piston 508b is moved by driving the piston driving unit 509. The syringe 508 is also connected to a tube 510 different from the tube 507. An electromagnetic valve 511 is connected to the other end of the tube 510. The electromagnetic valve 511 is connected to a pump 513 through a tube 512, and the pump 513 is connected to a cleaning liquid tank 515 that stores the cleaning liquid Lq through a tube 514. The piston drive unit 509, the electromagnetic valve 511, and the pump 513 are driven under the control of the control unit 34 included in the data processing unit 201.

  The sample nozzle 18n, the cylinder 508a, the tubes 507, 510, 512, and 514 are filled with the cleaning liquid Lq. When the sample Sp is aspirated or discharged, the piston drive unit 509 is driven and the piston is driven. By moving 508b, an appropriate suction pressure or discharge pressure is applied to the tip of the sample nozzle 18n via the cleaning liquid Lq. Since the air layer is interposed between the cleaning liquid Lq and the specimen Sp at the tip of the specimen nozzle 18n, the specimen Sp is not mixed with the cleaning liquid Lq when the specimen Sp is aspirated.

  Similarly to the sample dispensing mechanism 18 described above, the reagent dispensing mechanism 19 also includes an intake / exhaust mechanism using a syringe, and performs a reagent dispensing operation under the control of the control unit 34 of the data processing unit 201.

  For the specimen dispensing mechanism 18 and the reagent dispensing mechanism 19, in order to detect the liquid level at each lower end of the specimen nozzle 18n and the reagent nozzle 19n, for example, a capacitive liquid level detection mechanism may be provided. Is possible.

  The data processing unit 201 includes a keyboard, a mouse, and the like, and includes an input unit 31 for inputting information necessary for analyzing the sample and operation information of the automatic analyzer 1, a display device such as a liquid crystal, and a printer. An output unit 32 that outputs information relating to the analysis of the sample, a data generation unit 33 that generates analysis data of the sample based on the measurement result in the measurement unit 101, a control unit 34 that controls the automatic analyzer 1, and a measurement unit And a storage unit 35 that stores various types of information including the calculation result based on the measurement result 101.

  The data generation unit 33 calculates the absorbance of the liquid inside the reaction container 44 based on the measurement result sent from the photometry unit 16, or uses the calculation result of the absorbance and various information such as a calibration curve and analysis parameters. The component of the liquid inside the reaction container 44 is calculated.

  In addition to the analysis data generated by the data generation unit 33, the storage unit 35 includes analysis items, sample information, reagent types, sample and reagent dispensing amounts, sample and reagent expiration dates, and calibration curves used for analysis. Memorize parameters required for analysis.

  The data processing unit 201 having the above configuration is realized by a computer including a CPU, a ROM, a RAM, and the like.

  4 and 5 are diagrams for explaining the operation of the dispensing device 14 when the measurement unit 101 dispenses a sample. First, the specimen dispensing mechanism 18 moves the specimen nozzle 18n above the specimen container 41 that accommodates a symmetrical specimen, and inserts the tip of the specimen nozzle 18n into the specimen container 41 to aspirate the specimen. The support portion 504 is lowered.

  When the support portion 504 is lowered, the support portion 604 of the reagent dispensing mechanism 19 is also lowered in conjunction with it. Therefore, if the tip of the reagent nozzle 19n is positioned above the reagent container holder 12, the tip of the reagent nozzle 19n is There is a risk that the reagent container 43 or the like may be bent. Therefore, a region (reagent nozzle retracting region D1) that does not come into contact with other members even when the tip of the reagent nozzle 19n is lowered to the lowest point that can be reached is provided on the surface of the measurement unit 101, and the sample dispensing mechanism 18 is provided. Moves the tip of the reagent nozzle 19n to above the reagent nozzle retreat area D1 before dispensing the sample. The reagent dispensing mechanism 19 keeps the reagent nozzle 19n stationary in the reagent nozzle retracting area D1 while the sample dispensing mechanism 18 dispenses the sample.

  Since the sample dispensing mechanism 18 includes two arms, the arm length from the support unit 504 to the sample nozzle 18n can be changed. For this reason, the sample dispensing mechanism 18 adjusts the length of the arm from the support portion 504 to the sample nozzle 18n, thereby causing the sample nozzle 18n to reach all the sample containers 41 held by the sample container holder 11. (See FIG. 4). In addition, the sample nozzle 18n can be made to reach the sample nozzle cleaning unit 20 located away from the sample container holder 11.

  Thereafter, the specimen dispensing mechanism 18 that sucks a predetermined amount of specimen by the specimen nozzle 18n moves the specimen nozzle 18n to the specimen dispensing position A on the reaction container holder 13 and discharges the specimen to the reaction container 44 (FIG. 1). In the present embodiment, since the sample dispensing mechanism 18 is configured by two arms, it can be set to dispense at a place other than the sample dispensing position A shown in FIG.

  When the sample nozzle 18n is transferred to the sample dispensing position while the sample is sucked, the rack 42 on which the sample container 41 for storing the sucked sample is mounted and the rack 42 adjacent to the rack 42 are connected. It is preferable to pass through a position that is between and lower than the upper end of the specimen container 41. In this way, even if the sample Sp falls from the tip of the sample nozzle 18n, the dropped sample will not scatter and enter into another sample container 41. Accordingly, it is possible to reliably prevent contamination between samples when the sample nozzle 18n is moved.

  6-8 is a figure explaining operation | movement of the dispensing apparatus 14 when the measurement unit 101 dispenses a reagent. First, the reagent dispensing mechanism 19 moves the reagent nozzle 19n above the reagent container 43 that contains the reagent to be dispensed, and inserts the tip of the reagent nozzle 19n into the reagent container 43 to suck the reagent. The support portion 604 is lowered. When the support portion 604 is lowered, the support portion 504 of the sample dispensing mechanism 18 is also lowered in conjunction with it. Therefore, if the tip of the sample nozzle 18n is positioned above the sample container holder 11, the tip of the sample nozzle 18n is There is a risk that the specimen container 41 or the like may be bent when touched. Therefore, a region (sample nozzle retracting region D2) that does not come into contact with other members even when the tip of the sample nozzle 18n is lowered to the lowest point that can be reached is provided on the surface of the measurement unit 101, and the reagent dispensing mechanism 19 is provided. Before dispensing the reagent, the tip of the sample nozzle 18n is moved above the sample nozzle retreat area D2. The sample dispensing mechanism 18 keeps the sample nozzle 18n stationary in the sample nozzle retreat area D2 while the reagent dispensing mechanism 19 dispenses the reagent.

  Similarly to the sample dispensing mechanism 18, the reagent dispensing mechanism 19 is also composed of two arms, so the arm length from the support portion 604 to the reagent nozzle 19n can be changed. For this reason, the reagent dispensing mechanism 19 adjusts the length of the arm from the support portion 604 to the sample nozzle 18n, thereby causing the sample nozzle 18n to reach all the sample containers 41 held by the sample container holder 11. (See FIG. 6). In addition, the reagent nozzle 19n can be made to reach the reagent nozzle cleaning unit 21 located away from the sample container holder 11.

  The reagent dispensing mechanism 19 that has sucked a predetermined amount of reagent by the reagent nozzle 19n then moves the reagent nozzle 19n to the reagent dispensing position B on the reaction container holder 13 as shown in FIG. 44. It is also possible to dispense the reagent at a place other than the reagent dispensing position B.

  When the reagent nozzle 19n is transferred to the reagent dispensing position with the reagent sucked, it passes between the reagent containers 43 and the tip of the reagent nozzle 19n passes through a position lower than the upper end of the reagent container 43. Then, even if the reagent falls from the reagent nozzle 19n, the reagent does not enter the other reagent container 43. Therefore, contamination between reagents during the movement of the reagent nozzle 19n can be reliably prevented.

  By the way, in the above description, the reagent nozzle 19n is kept retracted to the reagent nozzle retracting area D1 at the time of sample dispensing, while the sample nozzle 18n is retracted to the sample nozzle retracting area D2 at the time of reagent dispensing. However, the sample and reagent dispensing method is not limited to this. For example, in view of the fact that the height of the tip of the sample nozzle 18n and the height of the tip of the reagent nozzle 19n are substantially the same, and the sample nozzle 18n and the reagent nozzle 19n can move in conjunction with the vertical direction, the sample nozzle 18n After the sample suction and the reagent nozzle 19n are sequentially suctioned, the sample and the reagent may be simultaneously discharged to different reaction containers 44 as shown in FIG. As a result, the analysis time can be shortened and more efficient analysis can be performed.

  According to the embodiment of the present invention described above, a specimen nozzle that discharges or sucks a specimen and one end of the specimen nozzle are attached, and the specimen is rotatable with respect to an axis parallel to the longitudinal direction of the attached specimen nozzle. A specimen dispensing mechanism having a nozzle transfer means, a reagent nozzle for discharging or aspirating a reagent, and one end of the reagent nozzle are attached, and the specimen nozzle transfer means has an axis parallel to the longitudinal direction of the attached reagent nozzle. A reagent dispensing mechanism that can be rotated independently of the sample nozzle transfer means with respect to an axis that coincides with the rotation axis and has a reagent nozzle transfer means for transferring the reagent nozzle. Space can be saved as compared with the case where the injection mechanism is provided separately, and downsizing of the apparatus can be realized.

  In addition, according to the present embodiment, the specimen dispensing mechanism and the reagent dispensing mechanism are configured using two arms via the connecting portion, so that the movable range of the specimen nozzle and the reagent nozzle is widened, and The degree of freedom of the position where the reagent can be dispensed into the reaction container is increased. Therefore, it is possible to cope with various reaction times between the specimen and the reagent.

  The best mode for carrying out the present invention has been described so far, but the present invention should not be limited only by the above-described embodiment. FIG. 10 is a diagram showing a configuration of a measurement unit included in an automatic analyzer according to another embodiment of the present invention. In addition to the configuration of the measurement unit 101 described above, the measurement unit 102 shown in the figure includes a rack 42 on which a sample container 41 that houses an emergency sample and a sample for accuracy control is included within the reach of the sample dispensing mechanism 18. And a reagent container holder 23 for the second reagent within a range that the reagent dispensing mechanism 19 can reach.

  FIG. 11 is a diagram illustrating a configuration of a measurement unit included in an automatic analyzer according to still another embodiment of the present invention and explaining its operation. In the measurement unit 103 shown in the figure, in view of the high degree of freedom in setting the reagent dispensing position in the reagent dispensing mechanism 19, the reagent to be dispensed first in the analysis step after washing is used as the washing liquid for the reaction container 44. Rg is applied. In FIG. 11, the photometric unit is not shown.

  FIG. 12 is a diagram showing an outline of the cleaning process of the reaction container 44 in the reaction container cleaning unit 24 of the measurement unit 103. In FIG. 12, the reaction container cleaning unit 24 first sucks the reaction liquid M of the specimen and the reagent in the reaction container 44 by the suction nozzle 241 (step (I)).

  Subsequently, the reagent nozzle 19n of the reagent dispensing mechanism 19 is transferred above the reaction vessel 44 (position C in FIG. 11), the tip is inserted into the reaction vessel 44, and the reagent Rg is discharged (step (II)). ). The reagent Rg used here is a reagent that is first dispensed in the analysis step performed using the reaction vessel 44 that has been washed.

  Thereafter, the reagent Rg as a cleaning liquid is sucked by the suction nozzle 242 of the reaction container cleaning unit 24 (step (III)).

  As described above, by using the reagent dispensed in the next analysis step as a cleaning liquid, a cleaning liquid discharging mechanism for discharging the cleaning liquid to the reaction vessel 44 as in the past becomes unnecessary, the apparatus configuration is simplified, and control is performed. Is also simplified. Moreover, the process of drying the reaction container 44 after washing is also unnecessary. Therefore, the apparatus can be further miniaturized and the cost can be reduced.

  In the above-described embodiment, the case where two dispensing mechanisms are provided has been described. However, three or more dispensing mechanisms may be provided. For example, a reagent dispensing mechanism for the first reagent and a reagent dispensing mechanism for the second reagent can be provided separately as the reagent dispensing mechanism.

  In addition, the number of the sample dispensing arms constituting the sample dispensing mechanism and the number of the reagent dispensing arms constituting the reagent dispensing mechanism are arbitrary, and the sample dispensing arm connecting part and the reagent are determined according to the number. The number of arm connecting portions for dispensing also changes (including the case where each arm connecting portion is not provided).

  Moreover, you may apply the detachable disposable nozzle as a sample nozzle or a reagent nozzle.

  Further, the automatic analyzer according to the present invention can be applied not only to the biochemical analysis of a specimen but also to the case of performing an immunological analysis of a specimen or the case of performing a genetic analysis of a specimen. it can.

  As is apparent from the above description, the present invention can include various embodiments and the like not described herein, and within the scope not departing from the technical idea specified by the claims. Various design changes and the like can be made.

It is a figure which shows the structure of the automatic analyzer which concerns on one embodiment of this invention. It is a figure which shows the structure of the principal part of a dispensing apparatus. It is a figure which shows the structure of a sample dispensing mechanism. It is a top view which shows the state of the dispensing apparatus at the time of aspirating a sample. It is a side view which shows the state of the dispensing apparatus at the time of aspirating a sample. It is a top view which shows the state of the dispensing apparatus at the time of aspirating a reagent. It is a side view which shows the state of the dispensing apparatus at the time of aspirating a reagent. It is a top view which shows the state of the dispensing apparatus at the time of discharging a reagent to a reaction container. It is a top view which shows the state which discharges a test substance and a reagent to a different reaction container simultaneously. It is a figure which shows the structure of the principal part of the automatic analyzer which concerns on another embodiment of this invention. It is a figure which shows the state at the time of reaction container washing | cleaning of the automatic analyzer which concerns on another embodiment of this invention. It is a figure which shows the outline | summary of the reaction container washing | cleaning process of the automatic analyzer which concerns on another embodiment of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Automatic analyzer 11, 22 Specimen container holder 12, 23 Reagent container holder 13 Reaction container holder 14 Dispensing apparatus 15 Stirring part 16 Photometric part 17, 24 Reaction container washing | cleaning part 18 Specimen dispensing mechanism 18n Specimen nozzle 19 Reagent dispensing mechanism 19n reagent nozzle 20 sample nozzle cleaning unit 21 reagent nozzle cleaning unit 31 input unit 32 output unit 33 data generation unit 34 control unit 35 storage unit 41 sample container 42 rack 43 reagent container 44 reaction container 101, 102, 103 measurement unit 201 data processing Units 241 and 242 Aspiration nozzles 501 Sample nozzle mounting arm (example of sample dispensing arm)
502 proximal arm (example of sample dispensing arm)
503 Arm connection (sample dispensing arm connection)
504, 604 Support section 505, 506, 605, 606 Arm drive section 507, 510, 512, 514 Tube 508 Syringe 508a Cylinder 508b Piston 509 Piston drive section 511 Solenoid valve 513 Pump 515 Washing liquid tank 601 Reagent nozzle mounting arm (Reagent dispensing) Example of arm)
602 Proximal arm (example of reagent dispensing arm)
603 Arm connection part (arm connection part for reagent dispensing)
D1 Reagent nozzle withdrawal area D2 Specimen nozzle withdrawal area Lq Cleaning liquid M Reaction liquid Rg Reagent Sp Specimen

Claims (6)

An automatic analyzer that analyzes a component of the specimen by reacting the specimen with a reagent and optically measuring a result of the reaction,
A sample nozzle for discharging or aspirating a sample, and a sample nozzle transfer means for attaching one end of the sample nozzle and being rotatable with respect to an axis parallel to the longitudinal direction of the attached sample nozzle; A sample dispensing mechanism having
A reagent nozzle that discharges or aspirates a reagent, and one end of the reagent nozzle is attached to an axis that is parallel to the longitudinal direction of the attached reagent nozzle and that coincides with the axis of rotation of the specimen nozzle transfer means A reagent dispensing mechanism that is rotatable independently of the sample nozzle transfer means and has a reagent nozzle transfer means for transferring the reagent nozzle;
An automatic analyzer characterized by comprising: The specimen nozzle transfer means includes
A plurality of sample dispensing arms including a sample nozzle mounting arm for mounting the sample nozzle; and a plurality of sample dispensing arm coupling portions that rotatably couple the sample dispensing arms adjacent to each other;
The reagent nozzle transfer means includes
A plurality of reagent dispensing arms including a reagent nozzle mounting arm for mounting the reagent nozzle, and a plurality of reagent dispensing arm connecting portions that rotatably connect the reagent dispensing arms adjacent to each other. The automatic analyzer according to claim 1.   3. The automatic analyzer according to claim 1, wherein the sample nozzle transfer unit and the reagent nozzle transfer unit are interlocked with each other in a direction parallel to the rotation axis.   The automatic analyzer according to any one of claims 1 to 3, wherein the height of the tip of the sample nozzle and the height of the tip of the reagent nozzle substantially coincide with each other. Even if the tip of the sample nozzle reaches the lowest point, the sample nozzle is a region that does not come into contact with other members, and is a region in which the sample nozzle is retracted at least while the reagent dispensing mechanism performs the reagent aspirating operation. Evacuation area,
A reagent nozzle that is an area that does not come into contact with other members even when the tip of the reagent nozzle reaches the lowest point, and that is an area in which the reagent nozzle is retracted at least while the specimen dispensing mechanism performs a specimen suction operation Evacuation area,
The automatic analyzer according to any one of claims 1 to 4, further comprising: The reagent dispensing mechanism is
6. When washing a reaction container for reacting a specimen and a reagent, in the analysis step after the washing, the reagent first dispensed into the reaction container is discharged as a washing liquid into the reaction container. The automatic analyzer according to any one of the above.

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