JP2006321758A - Cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic capable of preventing the skin from being excessively defatted, free from allergies or inflammations of the skin, even when the cosmetic is used, that is to say, lowly stimulative and having a function of inhibiting allergic symptoms, such as a warm sensation (a burning sensation) and eczema, and chapped skin. <P>SOLUTION: This cosmetic contains a scutellaria root extract and a phellodendron bark extract, or contains the scutellaria root extract and a licorice, or contains the phellodendron bark extract and the the licorice, or contains the scutellaria root extract, the phellodendron bark extract, and the licorice. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a cosmetic, and more particularly to a cosmetic having a skin irritation reducing action, a skin allergy suppressing action, a skin anti-inflammatory action, and an antibacterial action.

  Sensitive skin that is highly sensitive to cosmetics and allergic skin that is easily sensitized by sensitizing substances, surfactants, alcohols, preservatives, proteins used in cosmetics for the purpose of improving touch and moisture, Regardless of natural or synthetic, such as vitamins, minerals and other water-soluble ingredients, and oil-based agents emulsified with surfactants, these ingredients cause allergic symptoms and rough skin such as hot feeling (hot flashes) and eczema. It is easy to become.

  Cosmetics such as shampoos, facial cleansers, soaps and body soaps, hair cosmetics, skin care cosmetics, etc. are frequently used in daily body care, but these cosmetics contain the above ingredients, so the skin is strong. For those who are healthy, even though these cosmetics are comfortable to use, allergic symptoms such as heat (hot flashes) and eczema are likely to occur on sensitive and allergic skin.

  Also, soaps, soaps, lotions, lotions, packs, lip balms, lipsticks, blushers, eye shadows, sunscreen cosmetics, foundations, nail cosmetics, hair nourishing and hair stylings, There are similar problems with cosmetics that are applied to or adhered to the skin, such as hair dyes, hair removal cosmetics, shaving cosmetics, and permanent preparations.

  In this way, for allergic and inflamed skin, allergy and inflammation are sedated using a therapeutic anti-inflammatory cream or ointment. And as a cream as such a therapeutic agent, a licorice extract and Ogon extract, or an allergic dermatitis cream (Patent Documents 1 and 2) further containing an Aoba extract, a licorice extract and an Abou extract A cream for allergic dermatitis containing a liquid (Patent Document 3) has been proposed.

  However, these treatment creams do not prevent allergies or inflammation, but are treatments applied to the skin that has caused allergies or irritation. In daily life that comes in contact with various types of cosmetics, the use of such creams is particularly important for hairdressers and barbers who frequently touch cosmetics that do not take into account irritation or allergies, such as skin cleaners and hair cosmetics. It was difficult to soothe inflammation and inflammation.

  However, cosmetics are indispensable for most people today. Therefore, there is a demand for cosmetics that have low irritation and suppress allergic symptoms such as heat (hot flashes) and eczema and rough skin.

Japanese Patent No. 2609562 Japanese Patent No. 2609563 Japanese Patent No. 2609564

  Therefore, the present invention solves the above-mentioned problems, and cosmetics that do not cause excessive defatting from the skin, skin allergies or inflammation even when the above cosmetics are used, that is, low irritation and hot feeling (hot flashes) It is an object of the present invention to provide a cosmetic having a function of suppressing allergic symptoms such as sensation) and eczema and rough skin.

  The present invention for solving the above-mentioned problems is a cosmetic product characterized by containing an orange extract and an extract of buckwheat.

  Moreover, it is a cosmetic characterized by containing an ougon extract and licorice.

  Moreover, it is a cosmetic characterized by containing an alum extract and licorice.

  Moreover, it is a cosmetic characterized by containing an ougon extract, an alum extract and a licorice.

  According to the present invention as described above, due to the synergistic effect of the antiallergic action and anti-inflammatory action of the extract of buckwheat and the antibacterial action and anti-inflammatory action of the extract of buckwheat, excessive defatting from the skin even when used, It has become possible to provide a cosmetic product that does not cause allergies or inflammation, that is, a cosmetic product that has low irritation and has a function of suppressing allergic symptoms such as heat feeling (hot flush) and eczema and rough skin.

  Moreover, by adding licorice to the extract of Augon and / or Oat extract, the moisturizing action and anti-allergic action of licorice bring about the synergistic effect with the action of Ougon extract and / or Oat extract as described above, and more use Cosmetics that do not cause excessive defatting from the skin, skin allergies or irritation, that is, cosmetics that are less irritating and have the ability to suppress allergic symptoms such as heat (hot flush) and eczema and rough skin It became possible to provide.

  Hereinafter, embodiments of the present invention will be described in detail. The cosmetic of the present invention contains ougon extract, agaric extract and licorice.

  The cosmetics referred to in this application exclude the pharmaceuticals referred to in the Pharmaceutical Affairs Law, but are not limited to the cosmetics referred to in the Pharmaceutical Affairs Law, including quasi-drugs, cosmetics used on the skin, cosmetics used on the hair, and toothpaste. Cosmetics to be used on the skin include soap, synthetic soap, liquid body cleanser (body soap), cleanser such as facial cleanser, cleansing cream, cleansing lotion, makeup Cosmetics such as water, milky lotion, cosmetic liquid, lotion, liquid pack, paste-like pack, white powder such as powdered white powder, water white powder, whitened powder, powdered powder, foundation, lipstick, blusher, manicure, nail enamel, enamel remover, etc. Cosmetics used on the hair, such as nail cosmetics, eyeliner, eye shadow cosmetics, sunscreen cosmetics, suntan cosmetics, etc. Hair shampoos, rinses, treatments, hair tonics, hair conditioners, hair oils, hair liquids, hair mousses, hair gels and other hair nourishing and hair styling products (permanent wave preparations, hair dyes, etc.) And cosmetics such as hair removal cosmetics, and shaving cosmetics such as shaving lotions and after shaving lotions.

  The action of ougon in Chinese medicine is said to “remove inflammation, remove water poisoning, and have a refreshing fever and diuretic effect”. It has been confirmed that the general pharmacological action of ougon has a laxative action and a diuretic action. Further, since the component of ougon is a flavonoid, its anti-inflammatory action has been examined as a so-called vitamin P-like activity, and an effect comparable to aspirin has been recognized. Furthermore, regarding the antiallergic action of hornon, when a Schultz-Dale reaction is observed in the isolated ileum of sensitized guinea pigs, a strong inhibitory effect is recognized.

  Ougon is the main component of flavonoids: baicalin 4.3%, baicalein, wogolin 0.5%, wogolin glucoronide, orxylin A, and other steroids and saccharides that have anti-allergic activity are baicalin. Since the mediator release inhibitory action was similar to baicalin in molar ratio, the active structure is in the bailelein part. baiclein not only suppresses the anaphylaxis type reaction but also suppresses the atopy type reaction induced by reagin.

  In addition, the atopic inhibitor risodium chromicate (DSCG) has a common chromo skeleton with baicalalein, whereas DSCG can suppress only the reaction by regin, whereas baicalalein can also suppress the reaction by non-reagin. From the above, it can be understood that baicalalein acts on the action point that is not achieved by conventional drugs among the mechanisms of the development of allergic reactions. In addition, it is claimed that ougon has antibacterial action against Shigella, Salmonella typhi, Pseudomonas aeruginosa, staphylococci, hemolytic streptococci and the like.

  The hornon extract used in the present invention is not particularly limited, and for example, hornon extract extracted with ethanol, 1.3-butylene glycol, water or the like can be used. And as an example of the extract by ethanol, what contains baicalin 0.15-0.25 w / v% etc. are mentioned. In the present invention, this ougon extract is contained in the cosmetic in an amount of 0.01% by weight or more. Particularly preferred is 0.01 to 10% by weight. This is because if the amount is 0.01% by weight or less, sufficient effects may not occur. On the other hand, there is no particular upper limit of the content because there is no side effect caused by the inclusion of ougon extract, for example, the foaming is not bad in the cleaning agent.

  Oubak is a herbal medicine that contains berberine as a main component together with ouren and ougon, but its usage in Kampo is often different from ouren and ougon. There are many uses for the agaric that make it possible to infer the bactericidal action such as digestive action and eye diseases. In addition, it is reported that the medicinal effect of Aoba is characterized by its use as an external preparation, and berberine has an effect of promoting wound treatment that cannot be explained by a simple bactericidal action as an external bactericidal agent.

  As described above, the buckwheat has a bactericidal action, but has a growth inhibitory action against staphylococci at 5%, exhibits the strongest antibacterial activity against pneumococci, with berberine 0.625%, and the powdered apricot powder 0.015%. Inhibiting action up to the concentration.

In addition, the medicinal effect of Aoba has a wound healing action that cannot be explained by the strength of mere bactericidal action. For example, rabbits are able to heal 2 cm ² fresh wounds that have reached the muscles created on the back skin, compared with acrinol. Was obviously early. Since the bactericidal efficacy in test tubes is clearly weaker than that of synthetic fungicides, it seems that astringent anti-inflammatory action is involved in promoting healing. In addition, linoleic acid, esters of palmitic acid and phytosterin have been identified as components other than alba alkaloids.

  Traditionally, Aoba powder has been used for burns and baths, and in recent years, strong anti-inflammatory activity has been detected in screening studies of anti-inflammatory activity using fertilized eggs. That is, when the activity was examined using a filter paper disk in which the specimen was immersed in the embryo of a fertilized chicken egg to inhibit granulation formation as an index, the 50% methanol extracted crude extract of oak was 53% at a dose of 500 μg / dise. It showed granulation inhibitory action. Berberine hydrochloride showed 68.8% inhibition at a dose of 50 μg / dise. Ingredients involved in the inflammation of oak are not clear.

  Although the buckwheat extract used by this invention is not specifically limited, For example, the buckwheat extract extracted with ethanol, 1.3-butylene glycol, water, etc. can be used. And as an example of the extract by 1.3 butylene glycol, what contains 0.15-0.25 w / v% of berberine as berberine chloride is mentioned. In the present invention, the alum extract is contained in the cosmetic in an amount of 0.01% by weight or more. Particularly preferred is 0.01 to 10% by weight. This is because if the amount is 0.01% by weight or less, sufficient effects may not occur. On the other hand, there is no particular upper limit on the content because there is no side effect caused by the inclusion of the extract of a buckwheat, for example, there is no bad foaming in the detergent.

  Licorice has long been known as an anti-inflammatory medicinal herb, and its active ingredient, glycyrrhizic acid, has anti-inflammatory, anti-allergic, anti-peptic ulcer effects, etc. Some have been added to basic cosmetics and dentifrices as effective. It also has a moisturizing action. The licorice used in the present invention is not particularly limited, and licorice powder and licorice extract can be used.

  Although it is a licorice extract, glycyrrhizin and its glycyrrhetic acid have many pharmacological effects such as a water electrolyte of the adrenal cortex, a carbohydrate hormone-like action, an estrogen action, an antitussive action, an anti-inflammatory action, and an antiallergic action. Licorice contains a large number of glycyrrhizic acids, but monoacamonium glycyrrhizinate and potassium are soluble in hot water, but are gelled when allowed to cool and are hardly soluble in cold water. P-glycyrrhizic acid is easily soluble in pyridine, and in many cases it is insoluble in water such as insoluble in water. Dipotassium glycyrrhizinate is easily used because it dissolves 85% in water at room temperature.

  When dipotassium glycyrrhizinate is used, it is contained in the cosmetic in an amount of 0.01% by weight or more. This is because if the amount is 0.01% by weight or less, sufficient effects may not be obtained. In particular, it is preferably 0.01 to 10% by weight, and more preferably 0.1 to 2% by weight.

  In addition, it does not contain ougon extract, oak extract and licorice, but contains any two of them, that is, ougon extract and oak extract, or ougon extract and licorice. It is good also as preparing cosmetics by making it contain or containing an alum extract and a licorice.

  In addition to the above-mentioned components, the cosmetics of the present invention are appropriately selected and added according to the properties, purposes, dosage forms, etc. of the cosmetics within a range that does not impair the purposes, functions, and effects of the present invention. And use it. Other components include, for example, surfactants, oils, moisturizers, softeners, feel improvers, oiliness agents, emulsifiers, antioxidants, antiseptics, antifungal agents, emollients, pH adjusters, chelating agents, stabilization Agents, ultraviolet absorbers, alcohols, silicon compounds, thickeners, viscosity modifiers, solubilizers, pearlizing agents, fragrances, fresheners, bactericides, antibacterial agents, natural extracts, colorants, anti-fading agents, Examples include purified water and other solvents, propellants, and the like. These components may be used alone or in combination of two or more.

  Further, these various components can be appropriately used in the form of liquid, lotion, spray type, gel, wax, cream and the like. Moreover, there is no limitation in particular in the manufacturing method of the cosmetics of this invention, the addition method of said addition component, and compounding quantity, A well-known method and compounding quantity can also be employ | adopted.

  EXAMPLES The present invention will be described in more detail below with reference to examples of the present invention, but the present invention is not limited to these examples.

A shampoo agent having the composition shown below was prepared.
PEG-150 pentaerythrityl tetrastearate 1.5% by weight
N-lauroyl-L-glutamic acid triethanolamine 25.0% by weight
Sodium cocoamphoacetate 7.0% by weight
Glycerin 2.0% by weight
Phenoxyethanol 0.3% by weight
EDTA-2Na 0.5% by weight
Sodium chloride 0.5% by weight
Ougon extract 2.0% by weight
Oat extract 2.0% by weight
Dipotassium glycyrrhizinate 0.1% by weight
Purified water balance

  As a preparation method, purified water was heated to 80 ° C. and stirred with PEG-150 pentaerythrityl tetrastearate, N-lauroyl-L-glutamate triethanolamine, cocoamphoacetate sodium, glycerin, phenoxyethanol, EDTA-2Na and Sodium chloride is sequentially added and cooled to 50 ° C. with stirring until uniform. Further, agron extract, agaric extract and dipotassium glycyrrhizinate are sequentially added with stirring, and the mixture is stirred until uniform.

  The shampoo of the present invention of Example 1 above, the extract of Augon, the extract of Aoba and the commercially available shampoos A, B and C containing no licorice, four kinds of shampoos in total, one for each hairless mouse. The skin change was observed once a day and continuously for 1 week. With commercially available shampoos A, B and C, symptoms developed on the skin of the mice from the second day of continuous application.

  FIG. 1 is a photograph of the back of a hairless mouse after the lapse of 1 week, 1 using the shampoo of the present invention, and 2 to 4 using commercially available shampoos A, B, and C, respectively. FIG. 2 is a micrograph of a normal skin cross section before shampoo application as a control, FIGS. 3 to 5 are micrographs of the skin cross section after one week, and FIG. 3 is a diagram of 1 in FIG. 1 using the shampoo of the present invention. FIG. 4 shows the mouse of FIG. 1 using shampoo A, and FIG. 5 shows the mouse of FIG. 1 using shampoo B. FIG. 6 is a photomicrograph of the liver cross section of the mouse of FIG.

  Symptoms developed with commercial shampoos A, B, and C, although the degree of lesion was different. 1 and 4 using shampoo A show thickening of the epidermis, especially keratin, due to rough skin. In the example of the mouse of FIG. 1, 3, 5 and 6 using shampoo B, ulcers are seen in the skin, and internal lesions such as weight loss and inflammation in the liver and kidneys are also seen. A mild symptom was observed when the commercially available shampoo C was used. In contrast, as shown in FIGS. 1 and 3, the mice to which the shampoo of the present invention was applied showed the same state as the control shown in FIG. 2, and no change was seen before application.

A shampoo agent having the composition shown below was prepared.
Cationized cellulose 0.5% by weight
PEG-150 distearate 1.5% by weight
Sodium tetradecenesulfonate 15.0% by weight
Coconut oil fatty acid amidopropyldimethylbetaine 15.0% by weight
Etidronic acid 0.3% by weight
Phenoxyethanol 0.5% by weight
Glycerin 3.0% by weight
Ogon Extract 1.0% by weight
Oat extract 1.0% by weight
Purified water balance

  As a preparation method, cationized cellulose, PEG-150 distearate and purified water were heated to 80 ° C., and sodium tetradecenesulfonate, coconut oil fatty acid amidopropyldimethylbetaine, etidronic acid and phenoxyethanol were sequentially added while stirring. Cool to 50 ° C. with stirring until uniform. Further, glycerin, ougon extract, and buckwheat extract are sequentially added while stirring, and the mixture is stirred until uniform.

A shampoo agent having the composition shown below was prepared.
Polyoxyethylene sulfosuccinate lauryl disodium 20.0% by weight
N-coconut oil fatty acid acylglycine sodium 10.0% by weight
Sodium Lauraminopropionate 5.0% by weight
1,3-butylene glycol 3.0% by weight
Phenoxyethanol 0.5% by weight
EDTA-2Na 0.5% by weight
Citric acid 0.2% by weight
Ougon extract 0.2% by weight
Dipotassium glycyrrhizinate 0.8% by weight
Purified water balance

  As a preparation method, purified water is heated to 80 ° C. and stirred, polyoxyethylene sulfosuccinate lauryl disodium, N-coconut oil fatty acid acylglycine sodium, lauraminopropionate sodium, 1,3-butylene glycol, phenoxyethanol, EDTA-2Na and citric acid are sequentially added and cooled to 50 ° C. with stirring until uniform. Further, the augone extract and dipotassium glycyrrhizinate are sequentially added while stirring, and the mixture is stirred until uniform.

A treatment having the composition shown below was prepared.
Cationized hydrolyzed collagen 5.0% by weight
Behentrimonium chloride 1.0% by weight
Myristyldimethylamine oxide solution 5.0% by weight
Isopropyl myristate 5.0% by weight
Hydroxypropyl methylcellulose 1.0% by weight
Lactic acid monoethanolamide 3.0% by weight
Ogon Extract 0.5% by weight
Oat extract 0.5% by weight
Dipotassium glycyrrhizinate 0.3% by weight
Purified water balance

  As a preparation method, lactic acid monoethanolamide is mixed with purified water, and hydroxypropylmethylcellulose is heated to 80 ° C. with good stirring. Thereafter, cationized hydrolyzed collagen, behentrimonium chloride, myristyldimethylamine oxide solution and isopropyl myristate are added. Next, with stirring, ougon extract, buckwheat extract, and dipotassium glycyrrhizinate are added and stirred until uniform.

A treatment having the composition shown below was prepared.
Hydroxypropyl methylcellulose 1.5% by weight
Behentrimonium chloride 1.0% by weight
Acetyl monoethanolamide 3.0% by weight
Stearyldimethylbenzylammonium chloride 1.0% by weight
Cationized hydrolyzed silk 2.0% by weight
1,3-butylene glycol 1.0% by weight
Oat extract 0.2% by weight
Dipotassium glycyrrhizinate 0.6% by weight
Purified water balance

  As a preparation method, 1/3 amount of purified water is heated to 85 ° C., hydroxypropylmethylcellulose is dispersed in this warm water, 2/3 amount of purified water is added, and the mixture is stirred until it becomes a hydrate. Next, behentrimonium chloride, acetyl monoethanolamide and stearyldimethylbenzylammonium chloride are sequentially mixed after addition until it becomes transparent, and cooled to 40 ° C. Further, after adding cationized hydrolyzed silk and 1,3-butylene glycol and stirring until transparent, the agate extract and dipotassium glycyrrhizinate are added and stirred until uniform.

A treatment having the composition shown below was prepared.
Alkyltrimethylammonium chloride 6.0% by weight
Acetyl monoethanolamide 1.0% by weight
PEG almond glyceride 0.5% by weight
Polyoxyethylene stearyl ether 0.5% by weight
Cetanol 2.0% by weight
Mineral oil 3.0% by weight
Stearyl alcohol 2.0% by weight
Pentaerythritol tetrastearate 1.0% by weight
Triethanolamine 0.06% by weight
Hydrolyzed wheat germ protein 2.0% by weight
Glycerin 1.0% by weight
Ogon Extract 0.5% by weight
Oat extract 0.5% by weight
Dipotassium glycyrrhizinate 0.5% by weight
Purified water balance

  As a preparation method, alkyl trimethyl ammonium chloride, acetyl monoethanolamide and purified water are heated to 85 ° C. and mixed. PEG almond glyceride, polyoxyethylene stearyl ether, cetanol, mineral oil, stearyl alcohol and pentaerythritol tetrastearate are heated to 85 ° C and mixed, added to the mixture of alkyltrimethylammonium chloride, acetyl monoethanolamide and purified water, Cool to 45 ° C. While continuing stirring, triethanolamine is added, hydrolyzed wheat germ protein and glycerin are added, and then gonon extract, buckwheat extract, and dipotassium glycyrrhizinate are added and stirred until uniform.

A lotion having the composition shown below was prepared.
Hydroxyethyl cellulose 0.5% by weight
1,3-butylene glycol 2.0% by weight
Phenoxyethanol 0.5% by weight
Allantoin 0.1% by weight
Ougon extract 2.0% by weight
Dipotassium glycyrrhizinate 0.1% by weight
Purified water balance

  As a preparation method, hydroxyethyl cellulose, 1,3-butylene glycol, phenoxyethanol and purified water are heated to 80 ° C. and cooled to 50 ° C. with stirring until uniform. Next, allantoin, ougon extract and dipotassium glycyrrhizinate are sequentially added while stirring slowly, and the mixture is stirred until uniform.

A lotion having the composition shown below was prepared.
Sorbitol (70%) 5.0% by weight
Glycerin 5.0% by weight
Phenoxyethanol 0.5% by weight
Mono palm oil fatty acid POE (20) sorbitan 0.5% by weight
Tocopherol acetate 0.1% by weight
Ogon Extract 0.5% by weight
Oat extract 0.5% by weight
Dipotassium glycyrrhizinate 1.0% by weight
Purified water balance

  As a preparation method, sorbitol (70%), glycerin and phenoxyethanol are sequentially added and stirred in purified water at normal temperature. Next, the monococonut oil fatty acid POE (20) sorbitan and tocopherol acetate are mixed well and dispersed, and then charged into the agitated material and stirred. Further, with slow stirring, ougon extract, buckwheat extract and dipotassium glycyrrhizinate are sequentially added and stirred until uniform.

A lotion having the composition shown below was prepared.
Mineral oil 3.0% by weight
Lanolin alcohol 2.0% by weight
Cetyl alcohol 2.0% by weight
Glyceryl stearate 3.0% by weight
Cationized hydroxyethyl cellulose 0.5% by weight
Glycerin 3.0% by weight
Phenoxyethanol 0.5% by weight
Ogon Extract 1.0% by weight
Oat extract 1.0% by weight
Dipotassium glycyrrhizinate 0.2% by weight
Purified water balance

  As a preparation method, mineral oil, lanolin alcohol, cetyl alcohol and glyceryl stearate are heated to 80 ° C. and stirred to prepare oil phase A. In addition, after cationized hydroxyethyl cellulose and purified water are cooled and stirred to disperse, glycerin and phenoxyethanol are sequentially added, heated to 80 ° C. and stirred to adjust the aqueous phase B. Next, the water phase B is added to the oil phase A at 80 ° C., stirred until uniform, and cooled to 50 ° C. Further, with slow stirring, ougon extract, buckwheat extract and dipotassium glycyrrhizinate are sequentially added and stirred until uniform.

A body soap having the following composition was prepared.
Hydroxyethanediphosphonic acid 0.2% by weight
2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine
16.0% by weight
Lauroyl sarcosine sodium 14.2% by weight
Palm oil fatty acid sodium methylalanine 8.56% by weight
Palm oil fatty acid monoisopropanolamide 2.1 wt%
1.1% by weight of tetraoxystearate polyoxyethylene benterislit
Ogon Extract 0.5% by weight
Oat extract 0.5% by weight
Dipotassium glycyrrhizinate 0.6% by weight
Purified water balance

  As a preparation method, hydroxyethane diphosphonic acid and purified water are heated to 80 ° C. with stirring to prepare Preparation C. Further, coconut oil fatty acid monoisopropanolamide and tetrastearic acid polyoxyethylene benterislit are also heated to 80 ° C. with uniform stirring to prepare Preparation D. When Preparation C reaches 80 ° C., add 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, sodium lauroyl sarcosine, sodium palm oil fatty acid methylalanine and Preparation D in order and stir uniformly. To do. The mixture is cooled to 50 ° C., and slowly mixed with argon extract, buckwheat extract and dipotassium glycyrrhizinate and stirred until uniform.

A body soap having the following composition was prepared.
Lauroyl sarcosine sodium 40.0% by weight
Lauric acid amidopropyldimethylamine oxide solution 17.0% by weight
Polyoxypropylene (1) Palm oil fatty acid monoisopropanolamide 3.0% by weight
1.5% by weight of polyoxyethylene sorbitan triisostearate
Myristic acid 1.0% by weight
Myristyl alcohol 0.3% by weight
Propylene glycol 2.0% by weight
2.0% by weight ethylene glycol distearate
Phenoxyethanol 0.5% by weight
L-glutamic acid 0.2% by weight
Oat extract 1.0% by weight
Dipotassium glycyrrhizinate 0.2% by weight
Purified water balance

  As a preparation method, purified water and phenoxyethanol are heated to 80 ° C. with stirring to prepare Preparation E. In addition, polyoxypropylene (1) coconut oil fatty acid monoisopropanolamide, polyisoethylene stearic acid polyoxyethylene sorbitan, myristic acid, myristyl alcohol, propylene glycol and ethylene glycol distearate are heated to 80 ° C. with stirring, adjust. To the preparation E heated to 80 ° C., sodium lauroyl sarcosine and amidopropyldimethylamine oxide laurate solution are sequentially added while stirring, and then the preparation F is added and stirred uniformly. It cools to 50 degreeC, L-glutamic acid, an agate extract, and dipotassium glycyrrhizinate are thrown in in order, stirring slowly until it becomes uniform.

A body soap having the following composition was prepared.
Sodium polyoxyethylene lauryl ether sulfate 22.2% by weight
Lauric acid amidopropyldimethylamine oxide solution 20.0% by weight
N-coconut oil fatty acid acyl-potassium L-glutamate 7.0% by weight
Polyoxypropylene (1) Palm oil fatty acid monoisopropanolamide 3.0% by weight
Phenoxyethanol 0.3% by weight
Ogon Extract 0.3% by weight
Dipotassium glycyrrhizinate 0.8% by weight
L-glutamic acid 0.2% by weight
Purified water balance

  As a preparation method, phenoxyethanol and purified water are heated to 80 ° C. with stirring to prepare Preparation G. N-coconut oil fatty acid acyl-potassium L-glutamate and polyoxypropylene (1) Coconut oil fatty acid monoisopropanolamide is heated to 80 ° C. with stirring to prepare Preparation H. Polyoxyethylene lauryl ether sodium sulfate and amidopropyl dimethylamine oxide liquid were added to 80 ° C. preparation G while stirring, and further, preparation H was added and stirred, homogenized, cooled to 50 ° C., The extract, dipotassium glycyrrhizinate and L-glutamic acid are added sequentially and stirred until uniform to complete.

A body soap having the following composition was prepared.
Lauric acid 9.0% by weight
Myristic acid 4.5% by weight
Potassium hydroxide 4.0% by weight
Lauryldimethylamine oxide 8.0% by weight
Palm oil fatty acid amidopropyl betaine 8.0% by weight
Stearic acid diethanolamide 3.0% by weight
Glycol distearate 2.0% by weight
Betaine 1.5% by weight
Phenoxyethanol 0.5% by weight
Ogon Extract 0.3% by weight
Oat extract 0.3% by weight
Purified water balance

  As a preparation method, potassium hydroxide is dissolved in purified water, lauric acid and myristic acid are added with stirring, and the mixture is heated to 60 ° C. Next, lauryl dimethylamine oxide and coconut oil fatty acid amidopropyl betaine are added and stirred to prepare Preparation I. Further, in a separate kettle, stearic acid diethanolamide and glycol distearate are heated and stirred until they are completely dissolved, and then added to Preparation I, and betaine and phenoxyethanol are sequentially added and stirred, homogenized and cooled to 50 ° C. After that, the Ogon extract and the Oat extract are sequentially added and stirred until they are uniform.

A hair set agent having the composition shown below was prepared.
Linalyl acetate modified alcohol 3.0% by weight
Vinyl acetate / vinyl pyrrolidone copolymer 2.0% by weight
Sodium hyaluronate 0.001% by weight
Aminoethyl-aminopropylsiloxane dimethylsiloxane copolymer emulsion
1.0% by weight
Ougon extract 2.0% by weight
Oat extract 2.0% by weight
Dipotassium glycyrrhizinate 2.0% by weight
Purified water balance

  As a preparation method, a vinyl acetate / vinyl pyrrolidone copolymer and purified water are mixed and stirred to be uniform, and then other components are slowly added in order and stirred until uniform.

A hair set agent having the composition shown below was prepared.
Linalyl acetate-modified alcohol 83.3% by weight
Vinyl acetate / vinyl pyrrolidone copolymer 10.0% by weight
Polyvinylpyrrolidone 3.0% by weight
Hydroxypropyl chitosan 1.5% by weight
Ogon Extract 1.0% by weight
Oat extract 1.0% by weight
Dipotassium glycyrrhizinate 0.2% by weight

  As a preparation method, linalyl acetate-modified alcohol, vinyl acetate / vinyl pyrrolidone copolymer and polyvinyl pyrrolidone are mixed and stirred to be uniform, and then other components are slowly added in order and stirred until uniform.

The 1st agent for two bath type cold waves of the composition shown below was prepared.
Ammonium thioglycolate 10.0% by weight
Monoethanolamine 1.0% by weight
Ammonia water 1.0% by weight
Mink oil 0.3% by weight
Liquid paraffin 0.5% by weight
Polyoxyethylene oleyl ether (20E.O.) 0.2% by weight
Polyoxyethylene oleyl ether (4EO) 0.02% by weight
Fragrance 0.1% by weight
Glycerin 0.5% by weight
Ogon Extract 0.8% by weight
Oat extract 0.8% by weight
Dipotassium glycyrrhizinate 0.3% by weight
Purified water balance

  As a preparation method, a composition other than glycerin is sequentially added to purified water and stirred uniformly, and finally glycerin is added and stirred uniformly.

The 2nd agent for two bath type cold waves of the composition shown below was prepared.
Sodium bromate 7.0% by weight
Polyoxyethylene lanolin 0.01% by weight
Cetyltrimethylammonium chloride 0.2% by weight
Edetate disodium 0.003% by weight
Dipolyoxyethylene oleylmethylammonium chloride 0.4% by weight
Phenoxyethanol 0.1% by weight
Polyoxynonyl phenyl ether 0.7% by weight
Propylene glycol 0.3% by weight
Ogon Extract 1.0% by weight
Oat extract 1.0% by weight
Dipotassium glycyrrhizinate 0.5% by weight
Fragrance 1.0% by weight
Purified water balance

  As a preparation method, the composition is sequentially added to purified water and uniformly stirred.

Photos of the back of hairless mice after one week of applying various shampoos Micrograph of normal skin cross section before shampoo application Micrograph of skin cross section after continuous application of shampoo of the present invention for one week Micrograph of skin cross section after one week continuous application of commercial shampoo A Micrograph of skin cross section after one week continuous application of commercial shampoo B Micrograph of liver cross section after one week continuous application of commercial shampoo B

Explanation of symbols

1 Photo of hairless mouse using shampoo of the present invention 2 Photo of hairless mouse using commercially available shampoo A 3 Photo of hairless mouse using commercially available shampoo B 4 Hairless mouse using commercially available shampoo C Photo of

Claims (4)

  A cosmetic comprising an ougon extract and an oak extract.   Cosmetics characterized by containing ougon extract and licorice.   Cosmetics characterized by containing agaric extract and licorice.   Cosmetics characterized by containing ougon extract, agaric extract and licorice.

Images