JP2006124363A - Anticonvulsant and health food, food and drink containing the same - Google Patents
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- 235000013305 food Nutrition 0.000 title claims abstract description 9
- 235000013402 health food Nutrition 0.000 title claims abstract description 9
- 240000007164 Salvia officinalis Species 0.000 claims abstract description 6
- 235000002020 sage Nutrition 0.000 claims abstract description 6
- 240000000662 Anethum graveolens Species 0.000 claims abstract description 5
- 235000010676 Ocimum basilicum Nutrition 0.000 claims abstract description 5
- 240000007926 Ocimum gratissimum Species 0.000 claims abstract description 5
- 235000002912 Salvia officinalis Nutrition 0.000 claims abstract description 5
- 206010010904 Convulsion Diseases 0.000 abstract description 4
- 230000036461 convulsion Effects 0.000 abstract description 4
- 238000011084 recovery Methods 0.000 abstract description 3
- 235000007227 Anethum graveolens Nutrition 0.000 abstract 1
- 235000017311 Anethum sowa Nutrition 0.000 abstract 1
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- 239000002994 raw material Substances 0.000 description 7
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 208000003265 stomatitis Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 102000012440 Acetylcholinesterase Human genes 0.000 description 1
- 108010022752 Acetylcholinesterase Proteins 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 240000007087 Apium graveolens Species 0.000 description 1
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 1
- 235000010591 Appio Nutrition 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
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- 206010061218 Inflammation Diseases 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 208000017657 Menopausal disease Diseases 0.000 description 1
- 208000019914 Mental Fatigue Diseases 0.000 description 1
- 206010049565 Muscle fatigue Diseases 0.000 description 1
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- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 235000017276 Salvia Nutrition 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
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- 206010041349 Somnolence Diseases 0.000 description 1
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
- 229960004373 acetylcholine Drugs 0.000 description 1
- 229940022698 acetylcholinesterase Drugs 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
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- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000002921 anti-spasmodic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 229940124575 antispasmodic agent Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
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- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002897 effect on convulsion Effects 0.000 description 1
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- 239000003889 eye drop Substances 0.000 description 1
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- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
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- 239000002304 perfume Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
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- 230000008569 process Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 230000007958 sleep Effects 0.000 description 1
- 230000037321 sleepiness Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
本発明は、抗痙攣剤及びこれを含む健康食品、飲食品に関する。 The present invention relates to an anticonvulsant, a health food containing the same, and a food and drink.
痙攣の回復に有効な手段は、医師の治療の他に、漢方薬「芍薬甘草湯」があります。また健康食品に関しては、カリウム、カルシウム、ビタミンB6、マグネシウムを含むものが有効であると知られていますが、これに特化した商品が見られません。漢方薬「芍薬甘草湯」は即効性があり有用ですが、用いる場合は副作用に注意が必要です。 In addition to the doctor's treatment, there is a Chinese herbal medicine “Yakuyaku Kanzo-to” as an effective means to recover from convulsions. In addition, for health foods, products containing potassium, calcium, vitamin B6, and magnesium are known to be effective, but there are no products specializing in this. The Chinese herbal medicine “Yakuyaku Kanzo-to” has immediate effect and is useful, but when using it, attention should be paid to side effects.
上の状況を鑑みて健康食品というかたちをとる抗痙攣剤、すなわち、抗痙攣作用を持ち副作用が少なく安全性が高い、また使用が簡便である点を満足するものを提供することを課題としました。 In view of the above situation, the objective was to provide an anticonvulsant that takes the form of health food, that is, an anticonvulsant that has low side effects, high safety, and ease of use. .
上記の目的を達成するため、コモンセージの葉、ディルの種子、スイートバジルの葉を含むことを特徴とした抗痙攣剤及びこれを含む健康食品、飲食品を摂取します。 In order to achieve the above objectives, we will consume antispasmodics and health foods and foods that contain common sage leaves, dill seeds and sweet basil leaves.
課題の解決に当たって、どの食品に抗痙攣作用があるかということ。またひとつの原材料にはその作用がなくとも、ほかの食品を組み合わせることによって効果が得られる可能性があることに留意しました。そして、野菜、果物、ハーブ、現在健康食品として用いられている原材料等、膨大な数の材料に対して選定作業を行った結果、本原材料を決定するに至りました。それぞれの原材料に対して従前に明らかになっている効果は以下のとおりです。 Which foods have anticonvulsant action in solving the problem? We also noted that even if one raw material has no effect, it may be effective by combining other foods. And as a result of selection work for a huge number of ingredients such as vegetables, fruits, herbs, and ingredients currently used as health food, this ingredient was decided. The effects that have been previously revealed for each raw material are as follows.
コモンセージは、シソ科の多年草で、和名を「薬用サルビア」といいます。古来より薬効があり芳香がすることから万能の薬草として重要なハーブとされており、「セージを自宅の庭に植えている人間がなぜ死ぬのか」等の格言もあります。その葉は、冠状動脈の血流を増し血管を拡張させ、血液の循環をよくし血圧および血糖値を下げつつ、血液中のコレステロール値をも下げ免疫反応を強化します。解熱、抗炎症、殺菌、神経強壮、消化促進、浄血作用にすぐれ、血糖値を正常化して糖尿病の治療効果もあります。ホルモンのバランスをとり月経周期を整えホットフラッシュなど更年期障害の治療にも利用できます。さらには、授乳期の乳の出を抑え、発汗を抑制し、頑固な鼻づまりを緩和する働きもあります。最近では神経伝達物質アセチルコリンを破壊するアセチルコリンエステラーゼを阻害する働きがあり集中力と記憶力を高めて心を平穏にし、頭をすっきりさせることもわかってきました。また、抗酸化作用が強く老化防止や体の調子を整える効果もあり「若返りのハーブ」「不老のハーブ」とも呼ばれています。外用では抗菌、止血鎮痛作用があり、口内炎、歯茎の止血、うがい薬、抜け毛の予防等にも使用されていました。筋肉疲労回復効果もあります。その他、肉の臭み消し、殺菌力、酸化防止作用をいかして肉の保存の際に使われます。 Common sage is a perennial of Lamiaceae, and its Japanese name is called “medicinal salvia”. It has been regarded as an important herb as an all-purpose medicinal herb because it has medicinal properties and aroma since ancient times, and there is a saying such as "Why humans planting sage in their gardens die". Its leaves increase coronary blood flow, dilate blood vessels, improve blood circulation, lower blood pressure and blood sugar levels, lower blood cholesterol levels, and enhance immune responses. It has excellent antipyretic, anti-inflammatory, bactericidal, nerve tonicity, digestion promotion, blood purification, normalizing blood sugar levels, and has the effect of treating diabetes. It can be used to treat menopausal disorders such as hot flashes by balancing the hormones and adjusting the menstrual cycle. In addition, it can help prevent milk production during breastfeeding, reduce sweating, and relieve stubborn nasal congestion. Recently, it has been found that it has the function of inhibiting acetylcholinesterase, which destroys the neurotransmitter acetylcholine, improving concentration and memory, calming the mind, and refreshing the head. It is also called “Rejuvenation Herb” and “Unaged Herb” because of its strong anti-oxidant effect and anti-aging effect and toning the body. It has antibacterial and hemostatic analgesic effects for external use, and has been used to prevent stomatitis, gum hemostasis, mouthwash, and hair loss. There is also a muscle fatigue recovery effect. In addition, it is used for meat preservation by making use of meat odor elimination, bactericidal power, and antioxidant action.
ディルはセリ科の一年草で、その種子は、鎮静・睡眠・消化促進、駆風作用があることが知られています。 Dill is an annual plant of the celery family, and its seeds are known to have sedation, sleep, digestion, and wind drive.
スイートバジルはシソ科の一年草で、古代ギリシャ貴人は薬物、香水、浴物に用いました。ギリシャ語の「王者のハーブ」を意味するバジリコン・プトンの略語が名前になったことからも、古来より非常に効果がある植物として扱われてきたことが分かります。和名は、「メボウキ」(目箒)といって種子を目薬として使っていたためにつけられた名前です。その葉は、頭痛、のどの痛み、咳、風邪、口内炎、神経痛、呼吸困難に対して効果があり消化補助、精神安定作用があることも知られています。外用としては、虫刺され、かゆみ、炎症に用いられます。その他エッセンシャルオイルとして、ハーブの中でも最高の神経強壮作用があります。精神疲労、眠気目覚まし、頭痛、めまい、鼻づまり、緊張、月経痛(使用に対しては注意が必要)に対して用いられます。 Sweet basil is an annual plant of the Labiatae family, used by ancient Greek nobles for drugs, perfumes and baths. The name of the abbreviation for Basilikon Puton, which means “herb of the king” in Greek, indicates that it has been treated as a very effective plant since ancient times. The Japanese name is the name given to mebokki (mebuki) because it used seeds as eye drops. It is also known for its effects on headache, sore throat, cough, cold, stomatitis, neuralgia, dyspnea, digestive aids and tranquilization. For external use, it is used for insect bites, itching and inflammation. As an essential oil, it has the best nerve tonic among herbs. Used for mental fatigue, sleepiness awakening, headache, dizziness, stuffy nose, tension, menstrual pain (use with caution).
どの原材料も古くから薬用として親しまれていますが、抗痙攣作用があることは知られていませんでした。しかし、今回それぞれに抗痙攣作用があること、また同時に用いることによって特に優れた抗痙攣作用を発揮することを発見しました。加えて、本原材料は長年に渡り料理の材料に使われてきたので安全性が確立されています。 All raw materials have been popular for medicinal purposes since ancient times, but were not known to have anticonvulsant effects. However, this time, we have found that each of them has anticonvulsant activity and that it exhibits particularly excellent anticonvulsant activity when used at the same time. In addition, the ingredients have been used for cooking ingredients for many years, so safety has been established.
発明を実施するための最良の形態に記載の方法によって作られた抗痙攣剤を、痙攣の症状のある方4人(足のつりが主症状)に1日あたり0.2〜0.4gの範囲(症状によって前後しますが、1日に0.36gを摂取することを目標にすれば問題ない)で2週間を目標に食していただきました。その後、すべての人に対して以前からの症状が消失したという結果が得られました。従いまして、痙攣に優れた効果があることがいえます。 An anticonvulsant produced by the method according to the best mode for carrying out the invention is applied to 0.2 to 0.4 g per day for 4 persons having convulsions (mainly foot suspension). We had you eat for the purpose of 2 weeks in the range (it depends on the symptom, but there is no problem if you aim to take 0.36 g per day). After that, the result was that the previous symptoms disappeared for all people. Therefore, it can be said that it has an excellent effect on convulsions.
その他の利点としては、原材料の産地を限定する必要がないことが挙げられます。原材料によっては、産地によって効果が大きく変わるものがあるため生産性という観点から見たとき、影響が大きい場合が多々あります。しかし本原材料は、そのようなことがないため安定的に安く入手することができます。また、発明を実施するための最良の形態に記載の製造方法にあるとおり、原材料から成分を抽出する必要がないため工程が簡単で、コストを安価に抑えることもできます。 Another advantage is that there is no need to limit the origin of raw materials. Depending on the raw material, the effect may vary greatly depending on the production area, so when viewed from the viewpoint of productivity, the impact is often great. However, this raw material can be obtained stably and cheaply because there is no such thing. In addition, as in the manufacturing method described in the best mode for carrying out the invention, it is not necessary to extract ingredients from raw materials, so the process is simple and the cost can be kept low.
コモンセージの葉、ディルの種子、スイートバジルの葉を乾燥、粉末化したものを重量比、7:4:15で混合し、できたものが目的の抗痙攣剤です。1日あたり0.36gを目安に1回ないし複数回に分けて食し2週間程度続けます。飲食品に混ぜる場合は、摂氏60度以上の熱を加えないように注意します。 Common sage leaves, dill seeds and sweet basil leaves are dried and powdered and mixed at a weight ratio of 7: 4: 15 to produce the desired anticonvulsant. Eat about 0.36g per day once or multiple times and continue for about 2 weeks. When mixing with food and drink, be careful not to apply heat above 60 degrees Celsius.
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| JP2004343068A JP2006124363A (en) | 2004-10-28 | 2004-10-28 | Anticonvulsant and health food, food and drink containing the same |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010510266A (en) * | 2006-11-24 | 2010-04-02 | ディーエスエム アイピー アセッツ ビー.ブイ. | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory and / or joint disorders |
-
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- 2004-10-28 JP JP2004343068A patent/JP2006124363A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010510266A (en) * | 2006-11-24 | 2010-04-02 | ディーエスエム アイピー アセッツ ビー.ブイ. | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory and / or joint disorders |
| JP2013227328A (en) * | 2006-11-24 | 2013-11-07 | Dsm Ip Assets Bv | Use of tricyclic diterpene and the derivative for treatment, co-treatment or prevention of inflammatory disorder and/or joint disorder |
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