JP2003520063A - Article for applying topical composition and method for producing the same - Google Patents

Abstract

SUMMARY OF THE INVENTION The present invention comprises a topical composition permeable upper layer (6), a topical composition impervious lower layer (2) and at least one topical composition containing capsule (5). The two layers relate to an article for the application of the topical composition which is entirely overlapping and is held together by welding around it. The invention also relates to a method for producing said article.

Description

Detailed Description of the Invention

The present invention relates to an article for applying a topical composition, in particular a cosmetic or pharmaceutical composition, as well as a method for producing said article.

Cosmetic or pharmaceutical compositions for topical application, ie compositions for application to the skin and mucous membranes, are usually marketed in packages in the form of tubes or jars. The user must withdraw a small amount of the composition and then apply it with the finger to the desired zone of the skin or mucous membranes. However, this may leave the user's hands dirty when touching the topical composition and, in some cases, may leave an unpleasant feel. To avoid these disadvantages, fibrous media impregnated with the topical composition for direct application to the skin have been proposed. However, the fibrous media only partially eliminates contact between the topical composition and the user's hand.

Furthermore, users are increasingly demanding single-use products that are easy to implement, ready to use and convenient, especially in the field of skin care.

In EP 0,764,409 it has already been proposed to insert a powder, a solid gel or a bar cosmetic into a foam powder puff containing at least one foam block and having a welded joint. ing. The cosmetic is applied to the skin after activation by impregnating a foam block with a solution or emulsion.

However, packages of this kind are only suitable for products which can be provided in solid form. In particular, it is not a product that is actually easy to use at the point of use, since the foam must be pre-impregnated with liquid in order to activate the cosmetic product. In addition, once activated, the cosmetic product is intended to flow out of all the pores of the foam. Because of this, it is inevitable that the user's hand will come into contact with the activated cosmetic product.

Therefore, the applicant has solved the above-mentioned drawbacks, is easy to use because it is only used once, is easy to carry out, and avoids contact between the user's finger and the composition. It sought to develop an article for packaging and applying possible cosmetic or pharmaceutical topical compositions.

Accordingly, the present invention provides an article for applying a cosmetic or pharmaceutical topical composition, which article comprises a top layer permeable to said topical composition and a bottom layer comprising a fibrous material impermeable to said topical composition. Including the two layers described above being entirely overlapped and maintained together by welding around their perimeters to define a space in which at least one capsule containing the topical composition is placed. It is characterized by

In addition to the effects described above, the articles of the present invention can deliver a certain amount of topical composition and maintain it isolated from the air, thus providing stability to the composition. .

[0009]   Other effects of the present invention will be apparent from the following detailed description and drawings.

FIG. 1 is a partial cutaway perspective view of an article of the present invention containing several capsules containing a pharmaceutical or cosmetic topical composition.

[0011]   In the articles of the present invention, the upper layer typically also comprises a fibrous material.

Fibrous materials that can equally be used for the upper or lower layer are usually selected from materials that give the user a soft and comfortable sensation when in contact with the skin. Of course, non-abrasive materials are preferred. The fiber material may be woven or non-woven,
The latter is preferred.

The fibrous material may be formed by depositing fibers in a suitable medium that can provide the required soft and pleasant sensation.

Examples of woven or non-woven fibrous materials are natural products such as silk or natural cellulose (eg cotton or wood pulp); artificial products including regenerated cellulose (eg viscose or high tenacity viscose). ; Polyolefins (eg polyethylene, polypropylene or ethylene / propylene copolymers), polyesters (
Synthetic products including, for example, acetic acid-derived copolymers such as polyvinyl acetate), polyamides (eg nylon) or polyurethanes; 2 of the products mentioned above
There may be mentioned one or more mixtures, in particular mixtures based on viscose fibers and polyester fibers.

The fibers or individual fibers of the woven or non-woven fibrous material may be solid, hollow, porous or multilamellar or formed as bicomponent fibers such as polyester / viscose or polyester / polyamide fibers. obtain.

It may be advantageous for the fibrous material of the lower and upper layers to be heat fusible or thermoplastic. Some of the materials listed above have the above qualities and are especially polyolefins such as polyethylene. Furthermore, with the said materials, the welding between the two layers can be carried out easily, especially on an industrial scale, according to the method described below.

The bottom layer and the top layer may be composed entirely of at least one fibrous material as described above.

At least one of the upper and lower layers may be composed of a multi-layer structure including at least two sublayers. Several advantages may be obtained with the multilayer structure.

That is, the underlayer may have an outer sublayer of a permeable fibrous material of pleasant feel and an inner sublayer impermeable to the topical composition. The impermeable inner sublayer may be composed of a film of polymeric material, such as a polyolefin (eg, polyethylene, polypropylene or ethylene / propylene copolymer) film.

Further, each of the lower layer and the upper layer may have a multi-layer structure in which the inner sub-layers made of the above-mentioned thermoplastic or heat-fusible material are arranged so as to face each other so that they can be welded by the following method. Good. In this way, the outer sub-layer that the user touches may be composed of a material that is pleasant to the touch and soft, but does not necessarily have the appropriate quality to ensure good welding.

The multi-layer structure can be obtained by a method known to those skilled in the art, for example, by adhering opposite sides or calendering.

It is important that at least the lower layer is composed of fibrous material. This is because the material improves the grip of the article of the invention by the user and facilitates the proper application of the topical composition to the skin. This is more important when applied to the face, especially facial wrinkles, where the topical composition must be carefully and accurately spread.

[0023] Furthermore, the pleasant-feeling fibrous material may also allow the articles of the invention to be used by users who are particularly demanding in terms of cosmetics or pharmaceuticals.

According to the invention, the material is permeable to the topical composition as it can pass through the pores of the material.

Possible woven or non-woven fibrous materials are 20 to 250 g / m ² , preferably 100.
It may have a weight (ISO standard 9073-1) of ˜180 g / m ² .

The article of the invention may contain only one capsule containing the topical composition. However, usually multiple small capsules are used, each containing a portion of the topical composition. The small capsules are usually 0.5-5 mm, preferably 1-
It has an average diameter of 2.5 mm. The capsule is coated with a hydrophilic colloid such as albumin, alginate, casein, pectin, starch, gelatin, cellulose derivative (eg, ethyl cellulose, nitrocellulose, cellulose acetate), shellac, polyacrylic acid, polymethacrylic acid, polysaccharide, It can be composed of polyvinyl derivatives, polycarbonate or polystyrene. Gelatin is the preferred component of the capsule envelope.

[0027]   The gelatin may especially be pig, cow, sheep and fish gelatin.

The encapsulation ratio, ie the weight ratio of the total weight of the topical composition / capsule contained in each capsule, is usually 80-99%. Upon release of the composition contained in the capsule, the capsule must be able to be disintegrated by simply bending and manually pressing the article of the invention. According to another advantage of the invention, the user feels comfortable when the capsule is disintegrated through the layers.

The amount of capsules in the article of the invention is selected depending on the desired dose of the topical composition and the encapsulation ratio. The dosage of the topical composition itself depends on the type of composition and its intended use.

The manufacture of capsules is known to those skilled in the art. In this regard, for example, US Pat. Nos. 3,691,090 and 5,051 which are hereby incorporated by reference.
, 304 or 4,752,496. More specifically, capsules can be manufactured by coacervation using a coacervating agent. Examples of coacervating agents are aqueous containing organic and / or inorganic salts such as alkali metal salts, alkaline earth metal salts or ammonium salts of organic or inorganic anions (eg sulfuric acid, polyphosphoric acid, acetic acid and formate anions). An electrolyte solution may be mentioned. Sodium hexametaphosphate is the most suitable coacervating agent. The capsules obtained in this way are brittle and may be especially so when extracting from the reaction medium in which they are formed. To improve the brittleness of the capsule and reduce its solubility, the reaction medium may be cross-linked (for example
It is possible to add glutaraldehyde or formaldehyde).

Topical compositions are usually in liquid, paste, semi-paste or gel form. The topical composition may be a cosmetic composition, in particular a make-up product, a skin care product or a skin hygiene or cleansing product. The make-up product may in particular be a make-up foundation. The skin hygiene or cleansing product can be a makeup remover. The topical composition may also be a pharmaceutical composition, especially a dermatological or ophthalmic drug. The topical composition may also include a perfume in the form of an essential oil, water-alcohol solution or emulsion. Topical compositions are known per se and contain the active ingredient and / or customary excipients.

The articles of the present invention typically have a thickness of 5-20 mm. The article can be rectangular, triangular, square or circular. The diameter or long side of the article is usually 1 to 10 cm
Is. The thickness of each of the upper and lower layers may be 0.5-4 mm, preferably 1-3 mm.

FIG. 1 shows an article 1 of the invention, which is an impermeable underlayer 2, comprising an outer sublayer 3 made of non-woven natural cellulose and an inner sublayer 4 made of polyethylene film,
And a permeable upper layer 6 including an inner sub-layer 7 made of polyester and an outer sub-layer 8 made of viscose having a mixture of 30% by weight of polyester and 70% by weight of viscose as a main component, and above the inner sub-layer 4. A plurality of capsules 5 containing a topical composition have been deposited therein. The upper layer and the lower layer are entirely bonded by welding 9. In use, the capsules of the article of the present invention are broken by bending and pressing the article with a finger, which activates the topical composition, which activated composition migrates through the permeable top layer. . Then, advantageously, the topical composition may be applied to the skin by means of the fibrous material constituting the upper layer, without the topical composition coming into contact with the user's hands or fingers.

According to another aspect of the present invention, there is provided a method of manufacturing the article described above. In this method, capsules containing the topical composition are deposited on the inner surface of either the top or bottom layers of the article. The layer containing the deposited capsules and the other layer are then superposed over one another and the two layers are welded over their peripheries.

Welding can be carried out by heating, sonication, gluing, radio frequency or mechanical compression. When welding is performed by heating, ultrasonic waves or high frequency, at least the periphery of the upper layer and the lower layer must be made of a heat-meltable or thermoplastic material.

The articles of the present invention may be packaged in a case made of plastic material or in a two-layer structure having a metal (eg, aluminum) outer surface and a plastic inner surface that may contain one or more of the articles.

[0037]   The following examples serve to illustrate the invention.

[0038]   Example 1: Article containing encapsulated make-up foundation   a) 19.5 g of caprylic / capric triglyceride, ethyl palmitate
Ru-2-hexyl 11 g, ketostearyl octanoate 19.5 g, hydrogenated palm
Oil 5g, phenoxyethanol 1.45g, octyl methoxycinnamate 1g
, 0.2 g of ascorbyl palmitate, 0.05 g of EDTA powder, dimethyldis
Tearyl ammonium bentonite 0.3g, silica 5g, mica 4g, ultrafine powder
It has the composition of 20 g of talc, 2 g of nylon, 126 g of nylon and 25 g of pigment.
An anhydrous makeup foundation was prepared.

B) Encapsulation of make-up foundation In a beaker with a capacity of 600 ml, 5 g of pork gelatin was dissolved in 130 g of water,
It was allowed to expand and the mixture was brought to 55 ° C. with stirring at 220 rpm (water bath was used to maintain constant temperature during all operations). Agitation was kept constant so as to obtain capsules with an average diameter of 1,000 μm. Next, 25 ml of anhydrous make-up foundation was added, preheated to 55 ° C., and emulsified for 2 minutes. Then, 20 ml of 0.5% sodium hexametaphosphate dissolved in 90 ml of distilled water was preheated to 55 ° C. and then added.

The pH of the reaction medium was adjusted with 1N citric acid in order to lower the value to 4-5. A microscope was used to confirm that coacervation had occurred. The heating was discontinued and the reaction medium was allowed to return to room temperature in about 1.5 hours with stirring.

After the temperature was continuously lowered to about 15 ° C. using ice, 10 ml of 1.5% glutaraldehyde was added, and the mixture was reacted for 2 hours while stirring. During this period, the capsule was solidified corresponding to the crosslinking time.

Fine silica was added to the spatula to avoid capsules sticking together. After decanting the medium, it was filtered and rinsed with distilled water. The capsules were kept in water containing 0.5% preservative.

C) Manufacture of Articles Containing Encapsulated Make-up Foundation 4 g of capsules prepared according to the above method are treated with an outer non-woven layer based on a mixture containing 30% by weight of polyester fibers and 70% by weight of viscose fibers. Was also deposited on the inner sublayer consisting of the nonwoven polyester of the permeable layer. Then on this layer,
An impermeable layer comprising an inner sub-layer made of polyethylene film and an outer sub-layer made of non-woven natural cellulose was overlaid together.

Then, ultrasonic welding was performed between the periphery of the two layers. So just fold,
The product of the invention was obtained in which the capsules were activated by pressing and then the make-up foundation migrated through the permeable layer and the make-up foundation contacted the skin.

Examples 2-4 relate to articles of the invention containing various cosmetic compositions. These articles were made by the method described in Example 1, but differed from the articles of Example 1 only in the type of topical composition.

[0046]   Example 2: Product containing topical encapsulated makeup foundation   PEG-8-8% beeswax, liquid paraffin 10%, propylene glycol dipel
Lagonate (PGDP) 8%, cetyl alcohol 1.5%, isostearic acid
Sostearyl 2%, stearic acid 2%, finely divided pigment 6% and water up to 100 ml
A typical shade base having the following composition was prepared.

[0047]   Example 3: Article containing encapsulated oil-in-water emulsion composition   Liquid paraffin 25%, stearyl alcohol (2EO) 3.4%, steari
Alcohol (21EO) 1.6%, triethanolamine 0.25%, carbo
Paul ETD 2020 (acrylic polymer; Goodrich Corp.
Commercially available) 0.25%, phenoxy-2-ethanol 0.4%, propylene
Oil-in-water emulsion with a composition of 4% ren glycol and water up to 100 ml.
Was prepared.

[0048]   Example 4: Article containing a water-in-oil emulsion composition   Caprylic acid / capric acid triglyceride 19.5%, polypropoxy stealy
7.5% alcohol, 4% PEG-30 dipolyhydroxystearate, flow
Paraffin 5%, Parsol MCS (2-ethylhexyl methoxycinnamate
1%, commercially available from Givaudan), Oxynex LM (oxidized)
Inhibitor; commercially available from Merck) 0.2%, phenoxyethanol 1%
, NaCl 1%, water-in-oil emulsion with composition of water up to 100 ml
Prepared.

[Brief description of drawings]

FIG. 1 is a partial cutaway perspective view of an article of the present invention containing several capsules containing a pharmaceutical or cosmetic topical composition.

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 7/021 A61K 7/021 7/48 7/48 7/50 7/50 9/06 9/06 9 / 08 9/08 9/48 9/48 B65D 83/00 B65D 83/00 D (81) Designated countries EP (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE , IT, LU, MC, NL, PT, SE), OA (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG), AP ( GH, GM, K E, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW), EA (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM), AE, AG , AL, AM, AT, AU, AZ, BA, B, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU , ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA , ZW (72) Inventor Kalkby, Samira France, F-76800 Saint-Etienne Dou Le Bray, Lieu de Fine Land, 5 (72) Inventor Fortale, Sabine France, F-14360・ Trouville-Churle-Mer, Lieu-de-la- Cover, 57 F term (reference) 3E014 AA07 4C076 AA06 AA09 AA11 AA53 AA58 BB24 BB31 CC10 CC18 FF68 4C083 AA082 AA122 AC022 AC072 AC122 AC172 AC182 AC242 AC342 AC352 AC392 AC22 AC21 AC22 AC22 AC22 AC22 AC22 AC22 AC052 DD23 DD32 DD33 DD41 DD47 EE03 EE05 EE09

Claims (18)

[Claims] 1. An article for applying a cosmetic or pharmaceutical topical composition comprising: (i) a top layer permeable to the topical composition and (ii) a bottom layer composed of a fibrous material impermeable to the topical composition. Including the two layers described above being entirely overlapped and maintained together by welding around their perimeters to define a space in which at least one capsule containing the topical composition is placed. The article as described above. 2. Article according to claim 1, characterized in that the upper layer is made of fibrous material. 3. An article according to claim 1, wherein each of the lower layer and the upper layer is made of a non-woven fiber material. 4. The structure according to claim 1, wherein the lower layer has a multi-layer structure including an inner impermeable sub-layer and an outer sub-layer made of a fibrous material. Goods. 5. Article according to claim 4, characterized in that the inner impermeable sublayer consists of a film of polymeric material, preferably polyethylene. 6. Article according to claim 4 or 5, characterized in that the outer sublayer is made of cellulose. 7. Article according to any one of claims 1 to 6, characterized in that the topical composition is in liquid, paste, semi-paste or gel form. 8. Article according to any one of claims 1 to 7, characterized in that the topical composition is a cosmetic composition. 9. Article according to any one of claims 1 to 7, characterized in that the topical composition is a pharmaceutical composition, in particular a dermatological or ophthalmic pharmaceutical composition. 10. Article according to claim 8, characterized in that the cosmetic composition is a make-up product, a skin care product or a skin hygiene or cleansing product. 11. Article according to claim 10, characterized in that the make-up product is a make-up foundation. 12. Article according to claim 10, characterized in that the skin hygiene or cleansing product is a make-up remover. 13. Article according to any one of claims 1 to 12, characterized in that it comprises two or more capsules having an average diameter of 0.5 to 5 mm. 14. Article according to any one of claims 1 to 13, characterized in that the capsule comprises an envelope consisting of a hydrophilic colloid. 15. Article according to claim 14, characterized in that the capsule envelope consists of gelatin. 16. A method for producing an article according to any one of claims 1 to 15, wherein one or more capsules containing a topical composition are used as an upper layer or a lower layer. Depositing on the inner surface of the same and overlaying the other layers blanketly and welding the two layers together at their periphery. 17. Method according to claim 16, characterized in that the welding is carried out by heating, sonication, gluing, radio frequency or mechanical compression. 18. A first claim for the application of a topical cosmetic composition to the skin.
Item 16. Use of the article according to any one of items 15 to 15.