JP2003026560A - Activated oxygen-eliminating agent, skin cosmetic material for preventing aging, and method for stabilizing activated oxygen-eliminating activity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an activated oxygen-eliminating agent and a skin cosmetic material, having an excellent skin aging-preventing effect by promoting the keratinization of epidermis, further eliminating the activated oxygen to inhibit the production of a peroxylipid on the skin. SOLUTION: This activated oxygen-eliminating agent is characterized by containing a plant extract containing a flavonoid and/or tannin and an oil soluble ultraviolet light-absorbing agent solubilized in water, and a skin cosmetic material containing the activated oxygen-eliminating agent is also provided.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an active oxygen scavenger and a skin cosmetic, and more specifically, it promotes keratinization of the epidermis and further eliminates active oxygen to suppress the production of lipid peroxide in the skin. Relates to an active oxygen scavenger and a skin cosmetic having an excellent effect of preventing skin aging.

[0002]

2. Description of the Related Art Lipid peroxide increases in aged skin,
Loss of flexibility and elasticity, increased wrinkles of the skin, and dry and non-rough rough skin symptoms are observed. As one of the causative substances causing these skin symptoms, so-called active oxygen, which is generated by the influence of ultraviolet rays, enzymes, etc. on oxygen in the atmosphere, is considered. Such active oxygen includes superoxide, hydroxy radical, singlet oxygen, hydrogen peroxide and the like. This active oxygen oxidizes fatty acids and produces peroxides. Moreover, the generated peroxide and active oxygen exert adverse effects on the living body such as cross-linking of collagen fibers, fragmentation of hyaluronic acid, partial cleavage of DNA helix, and tissue damage due to generation of chained radicals. As a result, it is said to promote aging of the body such as wrinkles, loss of elasticity and hair loss. Therefore, elimination of active oxygen is very important for the skin in terms of improving or preventing skin aging, and is an important factor required for skin cosmetics. Therefore, conventionally, a search for a substance having an action of eliminating active oxygen generated in the living body has been widely performed. Examples of substances that have been conventionally used as substances having such actions include natural-derived substances such as fat-soluble tocopherol (vitamin E) and water-soluble ascorbic acid (vitamin C). Then, BHT (butyl hydroxytoluene), BHA
(Butyl hydroxyanisole) and the like. In addition, some plant extracts have an action of eliminating active oxygen, and this action is mainly derived from the phenolic OH group in the molecule of flavonoids and tannins contained in the extract. it is conceivable that. Therefore, conventionally, it has been attempted to blend such a plant extract in a cosmetic composition to eliminate active oxygen and prevent skin aging.

[0003]

However, the present inventors have a problem that the flavonoids and / or tannins in such a plant extract have poor stability and, for example, their ability to eliminate active oxygen is reduced by ultraviolet rays. Found. It is considered that this is because the ultraviolet irradiation causes intermolecular bonding due to the phenolic OH group, which is the active site, thereby blocking the active site.

Therefore, an object of the present invention is to solve the above problems in an active oxygen scavenger containing a plant extract containing flavonoids and / or tannins.

[0005]

Means for Solving the Problems The inventors of the present invention have made extensive studies, and as a result of incorporating a solubilized oil-soluble ultraviolet absorber together with the plant extract, the activity of flavonoids and / or tannins in the extract is exhibited. A decrease in oxygen scavenging ability was prevented, and a more stable active oxygen scavenger could be obtained. Surprisingly, the oil-soluble UV absorber does not exert such an effect when it is simply added to the formulation, and by solubilizing it in the formulation with an appropriate solubilizer, It turned out to be effective. That is, the present invention is characterized in that it contains a plant extract containing flavonoids and / or tannins, and a solubilized oil-soluble UV absorber for maintaining the active oxygen scavenging ability of the plant extract. And stable active oxygen scavenger. Further, it is an anti-aging skin cosmetic which comprises such an active oxygen scavenger.

One embodiment of the active oxygen scavenger of the present invention is
The plant extract containing flavonoids and / or tannins is preferably 0.0001 to 5 mass% in terms of dry residue.
And a solubilized oil-soluble UV absorber, which is also preferably contained in an amount of 0.0001 to 5% by mass in terms of dry residue, which is an active oxygen scavenger.

[0007] In a preferred embodiment of the present invention, the plant extract comprises ashitaba, aspalathus linealis, acacia yak, arnica, ginkgo, nettle, oolong tea, ages, sardines, hypericum, chamomile, sagebrush, liquorice, goldfish, cranberry fruit, Clara, ginger ginger, black tea, comfrey, soapless, hawthorn, linden, peony, birch,
Horsetail, Eustoma japonicus, Sambucus nigra, Eurasian mud, Eurasian peppermint, sage, mallow, tea, clove, chinpi, Centella asiatica, Tencha, Tofu calendula, Dokudami, Nindou, Novara, Hibiscus flower,
It is at least one species selected from the group consisting of hamamelis, hikoshi, vine leaves, grape berries, buttons, hops, horse chestnuts, melissa, peach leaves, cornflowers, yukinoshita, yuzu, mugwort, rosemary, waremoko.
Further, the oil-soluble ultraviolet absorber is ethyl paraaminobenzoate, octyl paradimethylaminobenzoate, octyl paramethoxycinnamate, hydroxymethoxybenzophenone (oxybenzone), tetrahydroxybenzophenone, 4-t-butyl-4-methoxy-. It is preferably at least one selected from the group consisting of dibenzoylmethane, 2- (2-hydroxy-5-methylphenyl) benzotriazole and its derivatives.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION The plant extract used in the present invention is characterized by containing flavonoids and / or tannins. Flavonoids include flavones, flavonols, isoflavones, flavanones,
Compounds of flavanonols, chalcones, benzalcumalanones, anthocyans and their glycosides are included. Further, the tannin includes both hydrolyzable tannin and condensed tannin.

The plant extract used in the present invention includes, for example, ashitaba, asparasus linealis, acacia yak, arnica, ginkgo, nettle, oolong tea, aget, swordfish, gentian, chamomile, sagebrush, licorice, goldfish, cranberry fruit, Clara, ginger ginger, black tea, comfrey, soapless, hawthorn, linden, peony, birch,
Horsetail, Equisetum arvense, Sambucus nigra, Horseshoe, Mint, Sage, mallow, cock,
Centella asiatica, tencha, tea, clove, pearl millet, duckweed, nindo, nobara, hibiscus flower,
Examples include hamamelis, hikoshi, vine leaves, grape berries, buttons, hops, horse chestnuts, melissa, peach leaves, cornflowers, yukinoshita, yuzu, mugwort, rosemary, waremoko, and the like. Preferably, oolong tea, hypericum, chamomile, sagebrush, liquorice, ginger ginger, cranberry fruit, comfrey, hawthorn, linden, birch, tencha, grape leaf, button, hibiscus flower, peach leaf, yukinoshita, rosemary, tea, clove Among them, oolong tea, linden, tencha, grape leaf, peach leaf, clove, cranberry fruit, and hibiscus flower are particularly preferable.

There is no particular limitation on the method for preparing the plant extract, but usually, any part of the plant such as whole grass, roots,
Dry stems, flowers, shreds, etc., then water, methanol,
Ethanol, propanol, propylene glycol, and 1,3-butylene glycol, ethyl acetate, ether,
It is obtained by extraction with liquid paraffin, soybean oil, lower fatty acid glyceride, or a mixed solvent thereof by a leaching method or a percolation method. The obtained extract may be provided in any form of liquid, soft extract, gel and dry extract.

The blending amount of the plant extract is not particularly limited and can be appropriately selected depending on the efficacy of the cosmetic and the plant extract. Usually 0.0001 in terms of dry residue
It is preferable that the active oxygen scavenger or the anti-aging skin cosmetic is mixed in an amount of -5% by mass.

In the present invention, the stability of the active oxygen scavenging ability is, for a reliable evaluation, under more severe conditions than actually assumed, that is, an aqueous solution containing a plant extract is continuously irradiated with artificial sunlight, It was confirmed by measuring the active oxygen scavenging ability before and after that. In the present invention, as a preferred stabilizer, by adding the agent at a concentration of 0.1 to 5% by mass to a 10% by mass aqueous solution of a plant extract, the active oxygen scavenging ability of the aqueous solution can be maintained even under the above conditions. The oil-soluble ultraviolet absorber that enables the oil to be substantially or not easily reduced is included.

The oil-soluble ultraviolet absorber according to the present invention may be blended alone or in combination of two or more. As the oil-soluble ultraviolet absorber, ethyl paraaminobenzoate, octyl paradimethylaminobenzoate, octyl paramethoxycinnamate, hydroxymethoxybenzophenone (also known as oxybenzone), tetrahydroxybenzophenone, 4-t-butyl-4-methoxy- Dibenzoylmethane, octyltriazone and its derivatives are preferred.

The blending amount of the oil-soluble ultraviolet absorber is not particularly limited and can be appropriately selected depending on the form of the cosmetic and the blending amount of the plant extract. Preferably, the total amount of the active oxygen scavenger or the anti-aging skin cosmetic is 0.
It is compounded at 0001 to 5 mass%. The oil-soluble ultraviolet absorber is blended in a solubilized form with a solubilizer usually used in cosmetics. Further, as the solubilizer for the oil-soluble ultraviolet absorber, a nonionic surfactant having an HLB of 10 or more is particularly preferable, and examples thereof include sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, propylene glycol fatty acid ester, and polyethylene. Glycol fatty acid ester, sucrose fatty acid ester, polyoxyethylene alkyl ether, polyoxypropylene alkyl ether, polyoxyethylene alkylphenyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid ester,
Polyoxyethylene glycerin fatty acid ester, polyoxyethylene propylene glycol fatty acid ester, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene phytostanol ether, polyoxyethylene phytosterol ether, polyoxyethylene cholestanol ether, polyoxy Ethylene cholesteryl ether, alkanolamide,
Examples include sugar ethers and sugar amides. The blending amount varies depending on the type and blending amount of the oil-soluble ultraviolet absorber, but with respect to the total amount of the active oxygen scavenger or the anti-aging skin cosmetic,
0.01 to 10 mass% is preferable.

In the active oxygen scavenger or anti-aging skin cosmetic of the present invention, in addition to the above-mentioned components, oils, surfactants, preservatives, perfumes, humectants, salts, solvents, which are usually used in cosmetics, Various components such as a neutralizing agent, a pH adjusting agent, an insect repellent, and a physiologically active ingredient can be used.

As the surfactant, there are anionic, cationic and amphoteric surfactants in addition to the above-mentioned nonionic surfactants, but they are not particularly limited, and they are used in ordinary cosmetics. Any of the above can be used. Illustrating specifically below, examples of the anionic surfactant include fatty acid soaps such as sodium stearate and triethanolamine palmitate, alkyl ether carboxylic acids and salts thereof, carboxylates such as condensation of amino acids and fatty acids, and alkyls. Sulfonic acid, alkene sulfonate, fatty acid ester sulfonate, fatty acid amide sulfonate, alkyl sulfonate and its formalin condensate sulfonate, alkyl sulfate ester salt, secondary higher alcohol sulfate ester salt, Alkyl and allyl ether sulfate ester salts, fatty acid ester sulfate ester salts, fatty acid alkylolamide sulfate ester salts, fungal oil and other sulfate ester salts,
Alkyl phosphates, ether phosphates, alkyl allyl ether phosphates, amide phosphates, N-acyl amino acid surfactants and the like; cationic surfactants such as alkyl amine salts, polyamines and amino alcohol fatty acid derivatives Amine salts, alkyl quaternary ammonium salts, aromatic quaternary ammonium salts, pyridinium salts, imidazolium salts and the like; amphoteric surfactants include betaine, aminocarboxylic acid salts, imidazoline derivatives and the like. When a surfactant is used, its content is preferably 0.1 to 20% by mass, more preferably 0.5 to 10% by mass, based on the total amount of the cosmetic.

As preservatives, alkyl paraoxybenzoate, benzoic acid, potassium benzoate, sorbic acid, potassium sorbate, phenoxyethanol, etc., and as antibacterial agents, benzoic acid, salicylic acid, carboxylic acid, sorbic acid, alkyl paraoxybenzoates. Esters, parachlorometacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, triclosan, photosensitizer, phenoxyethanol and the like.

Examples of the physiologically active ingredient used in the present invention include substances that give some physiological activity to the skin when applied to the skin. For example, anti-inflammatory agents, anti-aging agents, UV protective agents other than oil-soluble UV absorbers, tightening agents, antioxidants, hair growth agents, hair growth agents, moisturizers, blood circulation promoters, antibacterial agents,
Bactericide, desiccant, cooling agent, warming agent, vitamins (however,
Vitamins C and E are excluded), amino acids, wound healing promoters,
Examples include stimulants, analgesics, cell activators, enzyme components and the like. In the present invention, it is preferable to blend one kind or two or more kinds of these physiologically active ingredients.

Examples of physiologically active ingredients are deoxyribonucleic acid, mucopolysaccharides, sodium hyaluronate, chondroitin sulfate sodium, collagen, elastin, chitin, chitosan, biopolymers such as hydrolyzed eggshell membranes, estradiol, etenyl estradiol, etc. Moisturizing ingredients such as hormones, amino acids, sodium lactate, urea, sodium pyrrolidonecarboxylate, betaine, whey,
Oil components such as sphingolipids, ceramides, cholesterol, cholesterol derivatives, phospholipids, ε-aminocaproic acid, glycyrrhizic acid, β-glycyrrhetinic acid,
Lysozyme chloride, guaiazulene, hydrocortisone,
Anti-inflammatory agents such as allanto intranexamic acid and azulene,
Vitamins A, B ₂ , B ₆ , D, calcium pantothenate,
Biotin, vitamins such as nicotinic acid amide, allantoin, diisopropylamine dichloroacetate, 4-
Active ingredients such as aminomethylcyclohexanecarboxylic acid,
α-hydroxy acid, β-hydroxy acid, γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid, cell activating agents such as diisopropylaminodichloroacetate, γ-oryzanol, retinol, wound healing agents such as retinol derivatives, cepharanthin, Capsicum tincture, hinokitiol, garlic iodide extract, pyridoxine hydrochloride, nicotinic acid, nicotinic acid derivative, calcium pantothenate, D
-Pantothenyl alcohol, acetylpantothenyl ethyl ether, biotin, allantoin, isopropylmethylphenol, estradiol, ethinyl esteradiol, capronium chloride, benzalkonium chloride,
Cooling agents such as diphenhydramine hydrochloride, tacanal, camphor, salicylic acid, nonyl acid vanillyl amide, nonanoic acid vanillyl amide, piroctone olamine, glyceryl pentadecanoate, l-menthol, camphor, mononitroguaiacol, resorcin, γ-aminobutyric acid, benzethonium chloride, Examples include hair-growing agents such as mexiletine hydrochloride, auxin, female hormone, cantharis tincture, cyclosporine, zinc pyrithione, hydrocortisone, minoxidil, polyoxyethylene sorbitan monostearate, peppermint oil, and sasanishiki extract.

Examples of the pH adjusting agent include lactic acid, glycolic acid, succinic acid, dl-malic acid, potassium carbonate, sodium hydrogen carbonate, ammonium hydrogen carbonate, potassium dihydrogen phosphate, sodium monohydrogen phosphate and the like.

The active oxygen scavenger or anti-aging skin cosmetic of the present invention is not particularly limited in specific application, but skin care products, face washing products, scalp or hair products,
UV protection products, fragrance products and the like are mentioned as preferable ones, and antiaging skin cosmetics are particularly preferable. Further, as the dosage form, the oil-soluble UV absorber may be present in a solubilized state, such as lotion, calamine lotion, sunscreen agent, tanning agent, after-shave lotion, pre-shave lotion, pack fee, cleansing agent, Face wash, acne-preventive cosmetics, basic cosmetics such as essence, shampoo, conditioner, hair color, hair tonic,
Examples include setting agents, hair restorers, deodorants, body shampoos, hand soaps, and perfumes.

[0022]

EXAMPLES The present invention will now be described in detail with reference to examples, but the present invention is not limited thereto. The unit of the blending amount is shown by mass%, and the plant extract is calculated by dry calculation.

Test Example 1 (Active oxygen production inhibitory effect and lipid peroxide production inhibitory test) A sample having the composition shown in Table 1 below was prepared and filled in a glass bottle, and the low temperature sunshine weather meter SL80 was added thereto.
(Suga Test Instruments Co., Ltd.) was irradiated with artificial sunlight of 50,000 joules. The sample after irradiation was used for the following tests. The results are shown in Tables 2 and 3 below.

(1) Active oxygen production inhibition test (NBT method) 0.05 mM sodium carbonate buffer (pH 10.2)
2.4 ml, 3 mM xanthine 0.1 ml, 3 mM E
DTA 0.1 ml, 0.15% bovine serum albumin 0.1
ml, 0.75 mM nitroblue tetrazolium 0.1
0.1 ml is added to the composition of ml, and the mixture is heated at 25 ° C. for 10 minutes. Add 250 ml of 250-fold diluted xanthine oxidase (manufactured by Sigma) derived from buttermilk to it, and add it at 5 ° C.
React for 20 minutes. 0.1 ml of 6 mM copper chloride was added, the reaction was stopped, and the absorbance was measured at a wavelength of 560 nm using a spectrophotometer. Instead of the sample solution, 0.1% of 20% ethanol was added, and the absorbance was set to 100 to obtain the inhibition rate (%).

(2) Lipid peroxide production inhibition test (TBA
Method) 0.3 ml of methyl linoleate was added to 0.4 ml of the above sample,
1 mM hypoxanthine (including 0.1% Triton X-100)
3.0 ml, distilled water 0.15 ml, 20-fold diluted xanthine oxidase derived from buttermilk (manufactured by Sigma).
15 ml of the mixed solution is reacted by shaking at 37 ° C. for 24 hours.
0.3 ml of the above composition contained 0.1% phosphotungstic acid.
5 ml of 0.67% thiobarbituric acid 1.0 ml was added and stirred, heated at 95 to 100 ° C. for 30 minutes, rapidly cooled, n-butanol was added, and the mixture was shaken and stirred, and then centrifuged (3000 rp).
m, 10 minutes), and the supernatant was measured at a wavelength of 5 using a spectrophotometer.
Absorbance was measured at 35 nm. 2 instead of sample solution
Using the absorbance of 0.4 ml of 0% ethanol as a control, the inhibition rate (%) with respect to the control was determined.

[0026]

[Table 1] (Sample composition)

[0027]

[Table 2] (Test result A)

[0028]

[Table 3] (Test result B)

[0029]

[Table 4] (Test result C)

From Table 2 (test result A) and Table 3 (test result B), for each plant extract containing flavonoids and / or tannins described in the table, octyl paradimethylaminobenzoate, which is an oily ultraviolet absorber, is used. Octyl paramethoxycinnamate, tetrahydroxybenzophenone, hydroxymethoxybenzophenone (oxybenzone),
The samples to which 4-t-butyl-4-methoxy-dibenzoylmethane and octyltriazone were added respectively have an active oxygen production inhibitory effect and a lipid peroxide production inhibitory effect as compared with the sample without the oily ultraviolet absorber. As shown in Table 4 (Test result C), the above-mentioned oily ultraviolet ray protective agents alone have almost no active oxygen scavenging function.

Test Example 2 (Continuous test) Examples 1 and 2 and Comparative Example 1 with the following composition
Second lotion was prepared and filled in a glass bottle, which was then irradiated with 20,000 joules of artificial sunlight as above. Targeting 20 subjects, each sample after irradiation was separately applied to the left and right forearms once a day in the morning and evening for 4 weeks continuously, and evaluated for each evaluation item according to the following criteria, It evaluated by the total value of the score. The samples were set so that different samples were applied to the left and right of each subject, so that 10 samples could be evaluated for each sample.

(Criteria) 3: Significant improvement is seen. 2: Improvement is seen 1: A slight improvement is seen. 0: There is no improvement.

[0033] [Composition 1]     Amount of raw material components (% by mass)                                             Example 1 Comparative example 1 Ethanol 10 10 Polyoxyethylene hydrogenated castor oil (60EO) 1 1 Glycerin 33 1,3-butylene glycol 22 Dipropylene glycol 33 Polyethylene glycol 1500 1 1 Phosphate trace amount trace amount Edetate Trace amount Trace amount Methylparaben Trace amount Trace amount Hypericum extract 1.0 1.0 Paramethoxy cinnamate 0.1- Purified water Remaining amount Remaining amount

[0034] [Composition 2]     Amount of raw material components (% by mass)                         000 Example 2 Comparative Example 2 Ethanol 10 10 Polyoxyethylene hydrogenated castor oil (60EO) 1 1 Glycerin 33 1,3-butylene glycol 22 Dipropylene glycol 33 Polyethylene glycol 1500 1 1 Phosphate trace amount trace amount Methylparaben Trace amount Trace amount Sage extract 2.0 2.0 Paramethoxycinnamate 0.5- Purified water Remaining amount Remaining amount

[0035]

[Table 5] (Evaluation results)

As shown in the results in Table 5, when oil-soluble ultraviolet absorber octyl paramethoxycinnamate is added to a lotion containing St. John's wort extract or sage extract, which is a plant extract capable of scavenging active oxygen, It was confirmed that the skin aging preventive effect and the skin beautifying effect of the lotion were stabilized.

[0037]

As described above, in the present invention, a plant extract-containing skin cosmetic containing flavonoids and / or tannins known to have active oxygen scavenging ability is allowed to coexist with an oil-soluble ultraviolet absorber, It was possible to suppress the decrease in the active oxygen scavenging ability caused by ultraviolet rays during storage and use of the plant extract, and prevent the decrease in anti-skin aging activity of the skin cosmetic containing the plant extract.

Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 35/78 A61K 35/78 B CD F H H J K M N Q T V X 47/08 47/08 47/10 47/10 47/14 47/14 47/18 47/18 47/22 47/22 A61P 39/06 A61P 39/06 // A61K 31/352 A61K 31/352 F term (reference) 4C076 AA12 BB31 CC18 DD09F DD37A DD38A DD40Q DD45Q DD45R DD49Q DD60Q FF36 FF63 4C083 AA111 AA112 AB282 AC102 AC122 AC342 AC431 AC432 AC471 AC482 AC532 AC841 AD042 AD112 CC04 DD27 EE12 EE13 4C086 AA02 AB08 AB32 AB34 AB34 AB16 AB34 AB16 AB34 AB18 AB32 AB34 AB16 AB32 AB16 AB32 AB16 AB32 AB16 AB16 AB16 AB16 AB41 AB44 AB45 AB47 AB51 AB52 AB55 AB56 AB57 AB58 AB59 AB60 AB62 AB66 AB85 AB89 AC01 AC03 AC04 AC05 AC11 BA32 CA05 CA06 CA07 CA08 MA02 MA17 MA63 NA03 ZA89 ZC37

Claims (6)

[Claims] 1. An active oxygen scavenger comprising a plant extract containing flavonoids and / or tannins and an oil-soluble ultraviolet absorber solubilized in water. 2. A plant extract containing flavonoids and / or tannins is contained in an amount of 0.0001 to 5% by mass in terms of a dry residue, and an oil-soluble ultraviolet absorber is contained in an amount of 0.0001 to 5% by mass. The active oxygen scavenger according to claim 1. 3. The plant extract comprises ashitaba, asparagus linealis, asenyak, arnica, ginkgo, nettle, oolong tea, ages, sardines, hypericum,
Chamomile, kawara mugwort, licorice, goldfish, cranberry fruit, clara, ginger ginger, black tea, comfrey, soapless, hawthorn, linden, peony,
White birch, horsetail, western locust, western elderberry, western mouse, narwhal, sage, mallow, chinpi, centipede, tencha, tea, clove, eucalyptus, duckweed, ginkgo, nobara, hibiscus flower, hamamelis, Hikikoshi, grape leaf, grape Fruit, button, hop, horse chestnut, melissa, peach leaf,
The active oxygen scavenger according to claim 1 or 2, which is at least one kind of an extract of a plant selected from the group consisting of cornflower, yukinoshita, yuzu, mugwort, rosemary, and waremoko. 4. The oil-soluble ultraviolet absorber is octyl paradimethylaminobenzoate, octyl paramethoxycinnamate, hydroxymethoxybenzophenone (oxybenzone), tetrahydroxybenzophenone, 4-t-butyl.
At least 1 selected from the group consisting of 4-methoxy-dibenzoylmethane, octyltriazone and its derivatives
The active oxygen scavenger according to any one of claims 1 to 3, which is a seed. 5. An anti-aging skin cosmetic containing the active oxygen scavenger according to any one of claims 1 to 4. 6. A plant extract containing flavonoids and / or tannins, which comprises a plant extract containing flavonoids and / or tannins and an oil-soluble ultraviolet absorber solubilized in water, and the ability to eliminate active oxygen in the plant extract containing flavonoids and / or tannins. Stabilization method.