JP2002531069A - タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用 - Google Patents

タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用

Info

Publication number: JP2002531069A
Authority: JP; Japan
Prior art keywords: hvr; rvr; nucleic acid; polypeptide; seq
Prior art date: 1998-11-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP2000582560A

Other languages

English (en)

Japanese (ja)

Inventor

カーテイス，ロリ・エイ・ジエイ

Original Assignee

ミレニアム・フアーマシユーチカルズ・インコーポレーテツド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-13

Filing date

1999-11-12

Publication date

2002-09-24

1999-11-12 Application filed by ミレニアム・フアーマシユーチカルズ・インコーポレーテツド filed Critical ミレニアム・フアーマシユーチカルズ・インコーポレーテツド

2002-09-24 Publication of JP2002531069A publication Critical patent/JP2002531069A/ja

Status Pending legal-status Critical Current

Links

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239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000004659 sterilization and disinfection Methods 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
229940124530 sulfonamide Drugs 0.000 description 1
150000003456 sulfonamides Chemical class 0.000 description 1
239000006228 supernatant Substances 0.000 description 1
239000000829 suppository Substances 0.000 description 1
239000002511 suppository base Substances 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
208000011580 syndromic disease Diseases 0.000 description 1
230000002194 synthesizing effect Effects 0.000 description 1
238000010998 test method Methods 0.000 description 1
210000001103 thalamus Anatomy 0.000 description 1
229940126585 therapeutic drug Drugs 0.000 description 1
231100001274 therapeutic index Toxicity 0.000 description 1
230000004797 therapeutic response Effects 0.000 description 1
RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
229940033663 thimerosal Drugs 0.000 description 1
ZEMGGZBWXRYJHK-UHFFFAOYSA-N thiouracil Chemical compound O=C1C=CNC(=S)N1 ZEMGGZBWXRYJHK-UHFFFAOYSA-N 0.000 description 1
229960004072 thrombin Drugs 0.000 description 1
208000004371 toothache Diseases 0.000 description 1
238000011200 topical administration Methods 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
230000002103 transcriptional effect Effects 0.000 description 1
238000010361 transduction Methods 0.000 description 1
230000026683 transduction Effects 0.000 description 1
108091085767 transient receptor potential (TRP) ion channel family Proteins 0.000 description 1
238000011269 treatment regimen Methods 0.000 description 1
239000012588 trypsin Substances 0.000 description 1
238000010396 two-hybrid screening Methods 0.000 description 1
ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
241000701161 unidentified adenovirus Species 0.000 description 1
241001430294 unidentified retrovirus Species 0.000 description 1
238000011144 upstream manufacturing Methods 0.000 description 1
229940035893 uracil Drugs 0.000 description 1
238000001291 vacuum drying Methods 0.000 description 1
239000000105 vanilloid receptor agonist Substances 0.000 description 1
239000000085 vanilloid receptor antagonist Substances 0.000 description 1
238000005406 washing Methods 0.000 description 1
239000008215 water for injection Substances 0.000 description 1
238000001262 western blot Methods 0.000 description 1
229940075420 xanthine Drugs 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Cell Biology (AREA)
Peptides Or Proteins (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

JP2000582560A 1998-11-13 1999-11-12 タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用 Pending JP2002531069A (ja)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
US10832298P	1998-11-13	1998-11-13
US60/108,322		1998-11-13
US11407898P	1998-12-28	1998-12-28
US60/114,078		1998-12-28
US25863399A	1999-02-26	1999-02-26
US09/258,633		1999-02-26
US42113499A	1999-10-19	1999-10-19
US09/421,134		1999-10-19
PCT/US1999/026701 WO2000029577A1 (fr)	1998-11-13	1999-11-12	Nouveaux elements de la famille de proteines receptrices de capsicine/vanilloide, et utilisations de ceux-ci

Publications (1)

Publication Number	Publication Date
JP2002531069A true JP2002531069A (ja)	2002-09-24

Family

ID=27493638

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2000582560A Pending JP2002531069A (ja)	1998-11-13	1999-11-12	タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用

Country Status (5)

Country	Link
EP (1)	EP1131433A1 (fr)
JP (1)	JP2002531069A (fr)
AU (1)	AU2148000A (fr)
CA (1)	CA2348479A1 (fr)
WO (1)	WO2000029577A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2011037753A (ja) *	2009-08-11	2011-02-24	Japan Health Science Foundation	Ｔｒｐｖ２の部分ペプチド
JP2013520961A (ja) *	2010-02-26	2013-06-10	ヴェンタナメディカルシステムズ，インク．	中期染色体の細胞遺伝学的解析

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EP1009804B1 (fr)	1997-08-20	2003-10-29	The Regents of the University of California	Sequences nucleotidiques codant pour le recepteur de la capsicine, polypeptides lies au recepteur de la capsicine et leur utilisation
EP1047711B1 (fr) *	1998-01-22	2003-08-20	The Regents of the University of California	Sequences nucleotidiques codant le recepteur de la capsaicine
GB9827016D0 (en)	1998-12-08	1999-02-03	Merck Sharp & Dohme	Receptor protein
GB9907097D0 (en)	1999-03-26	1999-05-19	Novartis Ag	Organic compounds
US6482611B1 (en)	1999-09-23	2002-11-19	Neurogen Corporation	Human capsaicin receptor and uses thereof
ZA200300255B (en)	2000-07-20	2004-09-28	Bristol Myers Squibb Pharma Co	Tricyclic 2-pyridone compounds useful as HIV reverse transcriptase inhibitors.
MXPA03001627A (es) *	2000-09-02	2003-06-24	Gruenenthal Gmbh	Oligonucletodiso antisentido contra vr1.
DE10043674A1 (de) *	2000-09-02	2002-03-21	Gruenenthal Gmbh	Antisense Oligonukleotide
CA2425961A1 (fr)	2000-10-16	2002-04-25	Ortho-Mcneil Pharmaceutical, Inc.	Dosages de liaison de ligand ameliores pour des recepteurs vanilloides
US8641644B2 (en)	2000-11-21	2014-02-04	Sanofi-Aventis Deutschland Gmbh	Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US7344507B2 (en)	2002-04-19	2008-03-18	Pelikan Technologies, Inc.	Method and apparatus for lancet actuation
US9226699B2 (en)	2002-04-19	2016-01-05	Sanofi-Aventis Deutschland Gmbh	Body fluid sampling module with a continuous compression tissue interface surface
US7025774B2 (en)	2001-06-12	2006-04-11	Pelikan Technologies, Inc.	Tissue penetration device
US9427532B2 (en)	2001-06-12	2016-08-30	Sanofi-Aventis Deutschland Gmbh	Tissue penetration device
US9795747B2 (en)	2010-06-02	2017-10-24	Sanofi-Aventis Deutschland Gmbh	Methods and apparatus for lancet actuation
US9314194B2 (en)	2002-04-19	2016-04-19	Sanofi-Aventis Deutschland Gmbh	Tissue penetration device
US7547287B2 (en)	2002-04-19	2009-06-16	Pelikan Technologies, Inc.	Method and apparatus for penetrating tissue
US9795334B2 (en)	2002-04-19	2017-10-24	Sanofi-Aventis Deutschland Gmbh	Method and apparatus for penetrating tissue
US8702624B2 (en)	2006-09-29	2014-04-22	Sanofi-Aventis Deutschland Gmbh	Analyte measurement device with a single shot actuator
US8579831B2 (en)	2002-04-19	2013-11-12	Sanofi-Aventis Deutschland Gmbh	Method and apparatus for penetrating tissue
US8784335B2 (en)	2002-04-19	2014-07-22	Sanofi-Aventis Deutschland Gmbh	Body fluid sampling device with a capacitive sensor
US7713214B2 (en)	2002-04-19	2010-05-11	Pelikan Technologies, Inc.	Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US8360992B2 (en)	2002-04-19	2013-01-29	Sanofi-Aventis Deutschland Gmbh	Method and apparatus for penetrating tissue
US9248267B2 (en)	2002-04-19	2016-02-02	Sanofi-Aventis Deustchland Gmbh	Tissue penetration device
US8574895B2 (en)	2002-12-30	2013-11-05	Sanofi-Aventis Deutschland Gmbh	Method and apparatus using optical techniques to measure analyte levels
JP4621654B2 (ja)	2003-02-12	2011-01-26	バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト	ヒドロキシ−テトラヒドロ−ナフタレニル尿素誘導体
WO2006001797A1 (fr)	2004-06-14	2006-01-05	Pelikan Technologies, Inc.	Element penetrant peu douloureux
US8282576B2 (en)	2003-09-29	2012-10-09	Sanofi-Aventis Deutschland Gmbh	Method and apparatus for an improved sample capture device
EP1670761B1 (fr)	2003-10-01	2009-01-28	Xention Limited	Tetrahydro-naphtalene et derives d'uree
US9351680B2 (en)	2003-10-14	2016-05-31	Sanofi-Aventis Deutschland Gmbh	Method and apparatus for a variable user interface
US7683076B2 (en)	2003-11-08	2010-03-23	Bayer Schering Pharma Aktiengesellschaft	Tetrahydro-quinolinylurea derivatives
WO2005065414A2 (fr)	2003-12-31	2005-07-21	Pelikan Technologies, Inc.	Procede et appareil permettant d'ameliorer le flux fluidique et le prelevement d'echantillons
EP1751546A2 (fr)	2004-05-20	2007-02-14	Albatros Technologies GmbH & Co. KG	Hydrogel imprimable pour biocapteurs
WO2005120365A1 (fr)	2004-06-03	2005-12-22	Pelikan Technologies, Inc.	Procede et appareil pour la fabrication d'un dispositif d'echantillonnage de liquides
US9775553B2 (en)	2004-06-03	2017-10-03	Sanofi-Aventis Deutschland Gmbh	Method and apparatus for a fluid sampling device
NZ552086A (en)	2004-07-15	2009-12-24	Japan Tobacco Inc	Fused benzamide compound and vanilloid receptor 1 (VR1) activity inhibitor
US7906508B2 (en)	2005-12-28	2011-03-15	Japan Tobacco Inc.	3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity
WO2009126900A1 (fr)	2008-04-11	2009-10-15	Pelikan Technologies, Inc.	Procédé et appareil pour dispositif de détection d’analyte
US9375169B2 (en)	2009-01-30	2016-06-28	Sanofi-Aventis Deutschland Gmbh	Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8965476B2 (en)	2010-04-16	2015-02-24	Sanofi-Aventis Deutschland Gmbh	Tissue penetration device

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998039448A2 (fr) *	1997-03-07	1998-09-11	Human Genome Sciences, Inc.	186 nouvelles proteines secretees
EP1009804B1 (fr) *	1997-08-20	2003-10-29	The Regents of the University of California	Sequences nucleotidiques codant pour le recepteur de la capsicine, polypeptides lies au recepteur de la capsicine et leur utilisation
EP1047711B1 (fr) *	1998-01-22	2003-08-20	The Regents of the University of California	Sequences nucleotidiques codant le recepteur de la capsaicine
WO1999037765A1 (fr) *	1998-01-27	1999-07-29	Smithkline Beecham Plc	Homologues du recepteur humain des vanilloides
EP0943683A1 (fr) *	1998-03-10	1999-09-22	Smithkline Beecham Plc	Homologue humain du récepteur vanilloide Vanilrep1
EP0953638A1 (fr) *	1998-03-11	1999-11-03	Synthelabo	Canal cationique d'origine humaine homologue au récepteur vanilloide

1999
- 1999-11-12 JP JP2000582560A patent/JP2002531069A/ja active Pending
- 1999-11-12 EP EP99965787A patent/EP1131433A1/fr not_active Withdrawn
- 1999-11-12 WO PCT/US1999/026701 patent/WO2000029577A1/fr not_active Ceased
- 1999-11-12 AU AU21480/00A patent/AU2148000A/en not_active Abandoned
- 1999-11-12 CA CA002348479A patent/CA2348479A1/fr not_active Abandoned

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2011037753A (ja) *	2009-08-11	2011-02-24	Japan Health Science Foundation	Ｔｒｐｖ２の部分ペプチド
JP2013520961A (ja) *	2010-02-26	2013-06-10	ヴェンタナメディカルシステムズ，インク．	中期染色体の細胞遺伝学的解析

Also Published As

Publication number	Publication date
EP1131433A1 (fr)	2001-09-12
AU2148000A (en)	2000-06-05
WO2000029577A9 (fr)	2000-09-28
CA2348479A1 (fr)	2000-05-25
WO2000029577A1 (fr)	2000-05-25

Publication	Publication Date	Title
JP2002531069A (ja)	2002-09-24	タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用
JP2001517443A (ja)	2001-10-09	Ｔｎｆ受容体スーパーファミリーの新規な分子及びそれらの使用
CA2299055A1 (fr)	1999-02-11	Nouvelles molecules de la famille des proteines de type tango-77 et utilisations de ces molecules
US8133689B2 (en)	2012-03-13	Members of the capsaicin/vanilloid receptor family of proteins and uses thereof
JP2002501078A (ja)	2002-01-15	Ｓｐｏｉｌタンパク質及び核酸分子並びにそれらの使用
US6225085B1 (en)	2001-05-01	LRSG protein and nucleic acid molecules and uses therefor
US20020150988A1 (en)	2002-10-17	Novel molecules of the FTHMA-070-related protein family and the T85-related protein family and uses thereof
US6380382B1 (en)	2002-04-30	Gene encoding a protein having diagnostic, preventive, therapeutic, and other uses
JP2002516079A (ja)	2002-06-04	新規分泌型および膜会合型タンパク質ならびにそのための用途
JP2002528046A (ja)	2002-09-03	新規レセプタースーパーファミリー分子およびそれについての用途
AU753279B2 (en)	2002-10-17	Novel molecules of the T129-related protein family and uses thereof
WO2000000633A1 (fr)	2000-01-06	OCT1p, PROTEINE PRESENTANT UNE HOMOLOGIE AVEC LA FAMILLE DES PROTEINES ORGANIQUES ET TRANSPORTEUSES DE GLUCIDES ET UTILISATION
US6485921B1 (en)	2002-11-26	UBCLP and uses thereof
US6756212B1 (en)	2004-06-29	Isolated proteins and nucleic acid molecules having homology to the NIP2 protein and uses thereof
JP2002525117A (ja)	2002-08-13	Ｓｌｇｐタンパク質及び核酸分子並びにそれらの使用
US20020164330A1 (en)	2002-11-07	Novel molecules of the tango-77 related protein family and uses thereof
CA2348758A1 (fr)	2000-05-11	Molecules associees au lymphome et leurs utilisations
US20040209287A1 (en)	2004-10-21	OCT1p, a protein having homology to the organic and sugar transporter family of proteins, and uses thereof
CA2363605A1 (fr)	2000-08-31	Suppresseur de proliferation cellulaire induit par androgene et ses utilisations
US20020086982A1 (en)	2002-07-04	Novel EBI-3-ALT protein and nucleic acid molecules and uses therefor
CA2422846A1 (fr)	2002-04-04	Molecules associees aux lymphomes et utilisations
EP1586660A1 (fr)	2005-10-19	Nouvelles molécules de la famille des protéines liées à T85 et utilisation des dites molécules
US20020115185A1 (en)	2002-08-22	Neuronal cell death associated molecules and uses therefor
AU4829199A (en)	2000-01-10	Novel molecules of the t110-related protein family and uses thereof

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JP2002531069A - タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用 - Google Patents

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Landscapes

Applications Claiming Priority (9)

Publications (1)

Family

ID=27493638

Family Applications (1)

Country Status (5)

Cited By (2)

Families Citing this family (40)

Family Cites Families (6)

Cited By (2)

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