JP2002065644A - Device for measuring element - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a device for measuring elements being capable of accurately and precisely measuring the specified elements contained in a body liquid in a short period of time. SOLUTION: The element measurement device 1 is mainly composed of a device body 2, a cover 20, a finger receiver 3, a puncture medium 4 accommodated in a housing 5, a pump and a measurement means. The outer bottom surface of the device body 2 is externally curved in convex shape and a cone 23 is fixed in the bottom. This constitution makes the center of gravity of the element measurement device 1 to locate on the bottom side from its center; thus the element measurement device 1 is able to stand up because of its own weight even when it collapses. A tip 13 is anchored in the housing 5, whose extreme end is enclosed when a portion of receiving a finger tip 3 is pressed with the finger tip. A puncture needle attached to the tip 13 punctures the finger tip when a processing button 216 is pressed down, and the blood is sucked out from a portion to be punctured when the pump reduces inner pressures of the housing 5 and the portion to be punctured. The specified element contained in the collected blood is then measured by a measurement means 7 and processed by a controlling means 11 before the result thus obtained is displayed on a display 12.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a component measuring device, and more particularly, to a blood test, in which a fingertip is punctured with a puncture needle to collect blood and to determine the amount of a specific component such as glucose in the blood. The present invention relates to a component measuring device for measuring.

[0002]

2. Description of the Related Art In recent years, with the increase in the number of diabetic patients, autologous blood glucose measurement in which patients monitor daily fluctuations in blood glucose levels has been recommended.

In order to measure the blood sugar level, a test paper which develops a color according to the amount of glucose in the blood is mounted, blood is supplied to the test paper, the color is developed and developed, and the degree of the color development is measured optically. The measurement is performed using a blood glucose measuring device that measures (colorimeters) and quantifies the blood glucose level.

Prior to this measurement, a patient may take his or her own blood by puncturing the skin of the fingertip with a puncture device equipped with a puncture needle or a scalpel, and pressing around the puncture site with a finger or the like. The blood is squeezed out.

[0005] However, the fingertips are concentrated in capillaries and are suitable for collecting blood. On the other hand, since nerves are concentrated and painful, the pain and burden on the patient are great. Because it involves fear,
Many patients are unable to continue their own blood glucose measurements.

In a conventional blood glucose measurement, a puncture operation and
Since the blood sampling operation and the measurement operation are performed separately, the operability is also poor.

As a device capable of solving such a problem, there is known a blood glucose measuring device in which a puncturing device and a measuring device are integrated and provided with a suction means for squeezing blood (Japanese Patent Application No. Hei 10 (1999)). 183794, Japanese Patent Application No. 10-33
0057).

In these blood glucose measuring devices, first, a fingertip is pressed against the tip of the chip, and the opening of the tip is sealed so as to maintain airtightness.

Next, after puncturing the fingertip with a puncture needle protruding from the distal end opening, the suction means is operated (in a reduced pressure state) in this state, blood is drawn from the punctured site, and the blood is collected. Then, the blood glucose level of the collected blood is measured by the measuring device.

[0010] However, in the blood glucose measuring device, for example, at the time of measurement, the finger pressed by the movement of the patient may shift and a gap may be formed between the finger and the tip of the tip. As a result, even if the suction means is operated, the pressure cannot be sufficiently reduced, and the blood volume required for measuring the blood sugar level cannot be obtained, or it takes a relatively long time to obtain a sufficient blood volume. .

Further, there is a possibility that the blood glucose measuring device may be used in an inappropriate posture, for example, a vertical measuring device may be used in a horizontal position, thereby lowering the measuring accuracy.

[0012]

SUMMARY OF THE INVENTION An object of the present invention is to provide a component measuring device capable of accurately and reliably measuring a predetermined component in a body fluid in a short time.

[0013]

This and other objects are achieved by the present invention which is defined below as (1) to (10).

(1) A component measuring device for collecting a body fluid through an epidermis and measuring a component of the body fluid, which has a contact portion for applying the epidermis to an upper portion, and is capable of falling down or rolling. A component measuring device characterized in that it is configured to be able to return to its original state naturally.

(2) A component measuring device for collecting a body fluid through the epidermis and measuring a component of the body fluid, the device being provided on an upper portion and applying a skin to the epidermis; A space that is airtightly sealed by the pressure reduction means for reducing the pressure of the space, and a measurement means for measuring the amount and / or property of a predetermined component in the body fluid collected in the space, A component measuring device characterized by being configured to be able to fall down or to roll and to return to its original state naturally thereafter.

(3) A component measuring device for collecting a bodily fluid through the epidermis and measuring the component of the bodily fluid, comprising a puncture needle, a contact portion provided on an upper portion and adapted to puncture the epidermis to be punctured, Puncturing means for operating the puncture needle to puncture the epidermis applied to the part, together with a storage space for the puncture needle, decompression means for decompressing the puncture site of the epidermis by the puncture needle, and Measuring means for measuring the amount and / or property of the predetermined component in the collected body fluid, capable of falling down or rolling, and
A component measuring device characterized by being configured to be able to return to its original state naturally thereafter.

(4) The component measuring device has a housing which holds the tip provided with the puncture needle and has the puncture means therein, and the decompression means puts the storage space in the housing into a decompressed state. The component measuring device according to the above (3).

(5) The component measurement as described in (4) above, wherein the chip has a contact portion in contact with the epidermis, and is used by closing an opening formed inside the pertinent portion with the epidermis. apparatus.

(6) The component measuring apparatus according to (4) or (5), wherein the chip has a test paper and a passage for supplying a body fluid to the test paper.

(7) The component measuring apparatus according to (6), wherein the test paper is a test paper for measuring blood glucose.

(8) The component measuring device according to any one of the above (1) to (7), wherein an outer surface of a bottom portion of the component measuring device has a curved surface that is convex outward.

(9) The component measuring device according to any one of (1) to (8), wherein the components are arranged such that the center of gravity of the component measuring device is located on the bottom side from the center thereof.

(10) The component measuring device according to any one of the above (1) to (9), wherein a weight is provided near the bottom of the component measuring device.

[0024]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a component measuring apparatus according to the present invention will be described in detail based on a preferred embodiment shown in the accompanying drawings.

The component measuring device of the present invention is a device for collecting a body fluid (hereinafter, blood is representatively described in the present embodiment) through an epidermis (skin) and measuring a predetermined component of the body fluid. .

The part of the epidermis involved in the collection of the body fluid (in this embodiment, the puncture part) is preferably a finger, but may be, for example, a palm, a back of a hand, a side part of a hand, an arm,
Thighs, earlobes, and the like.

In the following embodiment, a component measuring apparatus in which a fingertip (finger) is punctured will be described as a representative.

FIG. 1 is a front view showing an embodiment (with a lid closed) of the component measuring apparatus of the present invention, FIG. 2 is a side view of the component measuring apparatus shown in FIG. 1 (with a lid opened), FIG. 3 is a longitudinal sectional view showing a configuration example of a chip used in the present invention,
FIGS. 4 and 5 are longitudinal sectional views each showing a configuration example of a puncturing means and a housing incorporating a puncturing means included in the component measuring device shown in FIG. 1, and FIGS.
FIG. 13 is a longitudinal sectional view showing a configuration example of a main part in the component measuring device shown in FIG. 1, FIG. 13 is a block diagram showing a circuit configuration of the component measuring device shown in FIG. 1, and FIG. It is a flowchart which shows the control operation | movement of a control means (a part contains operation | movement etc. of an operator). 1 to 11
Medium, upper side is "tip" or "upper", lower side is "base end",
It is described as “bottom” or “bottom”.

The component measuring device (blood component measuring device) 1 shown in these figures is a vertical type measuring device.

As shown in FIGS. 1, 2, 6 and 12, the component measuring device 1 comprises a main body (casing) 2 and a lid mounted to be rotatable (openable and closable) with respect to the main body 2. 20
A finger pad 3 installed on the main body 2, a puncturing means 4 housed in a housing 5, a tip retreat mechanism 6 provided on a proximal end side of the housing 5, and detection of blood (body fluid) collection. Measuring means 7 for measuring a predetermined component in the collected blood (body fluid), a pump 8 for reducing the pressure in the housing 5, and an electromagnetic valve 26 for releasing, relaxing or holding the reduced pressure in the housing 5. , A battery (power supply) 9, a control unit 11 provided on a circuit board (not shown), and a display unit 12.

The component measuring device 1 is used with a chip 13 mounted thereon. Hereinafter, each component will be described.

The main body 2 has a box shape. That is,
A storage space is formed inside the main body 2, and the puncture means 4, the housing 5, the tip retreat mechanism 6, the measurement means 7, the pump 8, the solenoid valve 26, the battery 9, and the storage space are formed in the storage space. The means 11 and the display unit 12 are respectively housed.

The outer surface of the bottom of the main body 2 has an outwardly convex curved surface. A weight 2 is provided at the bottom of the main body 2.
3 is fixed. Thereby, the center of gravity of the component measuring device 1 is located on the bottom side from the center.

Therefore, the component measuring device 1 can fall down and roll down, and thereafter can return to its original state naturally.

In other words, the component measuring device 1 can rise up by its own weight even if it falls down, as in a so-called “spilling up”. And when I got up,
As shown in FIG. 2, a finger pad 3 described later is located above the component measuring device 1. The posture at the time of rising is the proper posture of the component measuring device 1 (see FIGS. 1 and 2).

The weight 23 may be provided near the bottom of the main body 2.

Further, the weight 23 may be omitted, and predetermined components may be arranged such that the center of gravity of the component measuring device 1 is located on the bottom side from the center thereof. In this case, for example, a relatively heavy component may be disposed at the bottom of the main body 2 or near the bottom.

An opening 212 having a circular cross section is formed in the wall 211 on the tip side (upper side) of the main body 2 so as to penetrate the inside and outside of the main body 2. The chip 13 is mounted (held) on the housing 5 described later via the opening 212.

On the surface on the tip end side of the wall portion 211, a finger contact portion (a contact portion to which a skin is applied) 3 formed around the outer periphery of the opening 212 and corresponding to the shape of the fingertip (finger). Is installed. A finger contact surface 31 is provided on the distal end side of the finger contact portion 3.
Are formed. The component measuring device 1 is operated while the fingertip is in contact with the finger contact portion 3 (finger contact surface 31). Thereby, the fingertip is punctured, and the amount of a predetermined component (hereinafter, glucose is described as a representative in the present embodiment) in the collected blood is measured.

A lid 20 is rotatably supported by a shaft (rotating shaft) 213 at the tip (upper portion) of the main body 2.

As shown in FIG. 1, when the lid 20 is closed,
The tip of the main body 2 and the finger pad 3 are covered with the lid 20.

On the other hand, as shown in FIG. 2, when the lid 20 is opened, the tip of the main body 2 and the finger pad 3 are exposed to the outside, so that the attachment and detachment of the chip 13 and measurement can be performed.

A concave portion 214 is formed at the front end (upper portion) of the main body 2 on the front side. A finger can be hooked on the lid 20 from the recess 214, and the lid 20 can be easily opened.

A display window (opening) 219 penetrating the inside and outside of the main body 2 is formed on the front surface of the main body 2, and the display window 219 is closed by a plate-like member made of a transparent material. Is peeling.

The display unit 12 is installed at a position in the storage space corresponding to the display window 219. Therefore,
Various information displayed on the display unit 12 can be confirmed through the display window 219.

The display section 12 includes, for example, a liquid crystal display element (L
CD) and the like. The display unit 12 can display, for example, power on / off, power supply voltage (remaining battery level), measured value, measurement date and time, error display, operation guidance, and the like.

A recess 215 is formed at the front end (upper side) of the front surface of the main body 2.
An operation button 216 is provided in 5. In the component measuring device 1, by pressing the operation button 216, the pump (decompression unit) 8 is connected to the puncturing unit 4 described later.
Are configured to operate sequentially or almost simultaneously.

The power of the component measuring device 1 may be turned on by pressing the operation button 216.

Further, grip portions 218 are provided on both side surfaces of the main body 2, respectively. This grip part 21
8, the component measuring device can be easily and reliably gripped. This grip portion 218 can be formed of, for example, an elastic material.

The control means 11 is composed of, for example, a microcomputer and determines whether or not blood has been collected.
The various operations of the component measuring device 1 are controlled. In addition, the control unit 11 has a built-in arithmetic unit that calculates the amount of glucose in blood (blood sugar level) based on a signal from the measurement unit 7.

A pump 8 is installed in the storage space of the main body 2 as a pressure reducing means (suction means). The pump 8 is operated by electric power, and is connected to a ventilation path 54 formed in the housing 5 described later via a tube 81. This tube 81 has flexibility, for example, polyvinyl chloride, polyethylene, polypropylene, ethylene-vinyl acetate copolymer (EVA)
And other high-molecular materials such as polyolefins, polyamides, polyesters, silicone rubbers, and polyurethanes.

The pump 8 is provided in the cavity 5 of the housing 5.
By sucking and discharging the air in the housing 2, the housing 5
The inner cavity 52 is set in a reduced pressure state.

The pump 8 is capable of sucking blood from the puncture site of the fingertip (for example, 100 to 40).
(About 0 mmHg) as long as the pressure can be applied to the inner cavity 52 of the housing 5 and the puncture site at the fingertip.

In the storage space of the main body 2, a battery 9 is installed as a power source. This battery 9 comprises a pump 8,
It is electrically connected to the electromagnetic valve 26, the control means 11, the display unit 12, and the like, and supplies electric power necessary for the operation thereof.

The measuring means 7 optically detects that blood is supplied (collected) to the test paper 18 provided in the chip 13 described later, and optically measures the amount of glucose in the blood spread on the test paper 18. The installation position is near the lateral position where the test paper 18 is located with the chip 13 mounted and held in the housing 5.

As described above, the measuring means 7 has both the function of detecting the collection of blood and the function of measuring the amount of glucose (predetermined component) in the blood spread on the test paper 18. The number of parts can be reduced, the configuration can be simplified, and the number of assembling steps of the apparatus can be reduced as compared with the case where the means are separately provided.

The measuring means 7 has a light emitting element (light emitting diode) 71 and a light receiving element (photo diode) 72.

The light emitting element 71 is electrically connected to the control means 11, and the light receiving element 72 is electrically connected to the control means 11 via the amplifier 24 and the A / D converter 25.

The light emitting element 71 is activated by a signal from the control means 11 and emits light. This light is preferably pulsed light that emits intermittently at predetermined time intervals.

When the light emitting element 71 is turned on with the chip 13 mounted on the housing 5, the light emitted from the light emitting element 71 is irradiated on the test paper 18, and the reflected light is received by the light receiving element 72. Photoelectric conversion is performed. Light receiving element 72
Outputs an analog signal corresponding to the amount of received light, and after the signal is amplified as desired by the amplifier 24,
The signal is converted into a digital signal by the / D converter 25 and input to the control means 11.

The control means 11 determines whether or not blood has been collected, that is, whether or not blood has been spread on the test paper 18 of the chip 13 based on the input signal.

Further, the control means 11 performs a predetermined arithmetic processing based on the input signal, and performs a correction calculation if necessary, thereby obtaining the amount of glucose in blood (blood glucose level). The obtained blood sugar level is displayed on the display unit 12.

In the housing space of the main body 2, a housing 5 containing the puncturing means 4 and a chip retracting mechanism 6 connected to the base end of the housing 5 are provided.

The tip retracting mechanism 6 is fixed to the main body 2,
On the other hand, the housing 5 is not fixed to the main body 2, but is installed so as to be movable in the axial direction (vertical direction in FIGS. 1 and 2) by the chip retracting mechanism 6.

As described above, this component measuring device 1
The chip 13 is mounted on the housing 5 for use. As shown in FIG. 3, the tip 13 includes a puncture needle 14, a first housing 15 for slidably storing the puncture needle 14,
A second housing 16 installed on an outer peripheral portion of the first housing 15, a test paper fixing portion 17 installed on an outer peripheral portion of the second housing 16, and a test paper 18 fixed on the test paper fixing portion 17. It is composed of

The puncture needle 14 includes a needle 141 and a needle 141.
And a hub 142 fixed to the base end side of the first housing 15 and housed in the inner cavity 152 of the first housing 15.

The needle body 141 is formed of a hollow member or a solid member made of a metal material such as stainless steel, aluminum, an aluminum alloy, titanium, and a titanium alloy, and has a sharp cutting edge (needle tip) at its tip. Are formed. With this cutting edge, the surface (skin) of the fingertip is punctured.

The hub 142 is formed of a substantially columnar member, and its outer peripheral portion slides while being in contact with the inner peripheral surface 151 of the first housing 15.

A reduced diameter portion 143 is formed at the base end of the hub 142. The reduced diameter portion 143 is used for the needle holder 4 of the plunger 41 constituting the puncturing means 4 described later.
11 is fitted.

The first housing 15 is formed of a bottomed tubular member having a wall 153 as a bottom, and has a lumen 152 formed therein.

At a substantially central portion of the wall 153, a hole 154 having a circular cross section is formed. This hole 154
The needle 141 passes through when the fingertip (finger) is punctured. The hole diameter of the hole 154 is set smaller than the outer diameter of the tip of the hub 142. For this reason, when the puncture needle 14 moves toward the distal end of the inner cavity 152 and the distal end of the hub 142 abuts against the proximal end of the wall 153, the puncture needle 14 is prevented from further moving in the distal direction. Is done. Therefore, the length of protrusion of the needle body 141 from the tip of the tip 13 is kept constant when the fingertip is punctured. Therefore, it is possible to more reliably prevent the blade tip of the needle body 141 from piercing the fingertip deeper than necessary.

Further, a mechanism for adjusting the moving distance of the plunger 41 described later may be provided to adjust the puncturing depth of the fingertip by the cutting edge of the needle 141.

The outer peripheral portion of the first housing 15
Is fixedly mounted.

The second housing 16 is formed of a substantially cylindrical member, and has a lumen 161 formed therein.

At the tip of the second housing 16,
A contact portion 163 projecting in a ring shape is formed. The contact portion 163 is a portion where the fingertip is pressed, and inside the contact portion 163, a distal end opening (opening) 16 through which the lumen portion 161 is opened.
2 are formed. The outer peripheral edge of the distal end of the contact portion 163 has a shape suitable for exerting an effect of stimulating a peripheral portion of the puncture when pressed against a fingertip and relieving pain during puncture. Further, when the pressure is reduced by the pump 8, the shape is such that the inflow of air from between the tip of the contact portion 163 and the surface of the fingertip can be suppressed as much as possible. In addition,
The contact portion 163 may not be provided at the distal end of the second housing 16, and the distal end surface of the second housing 16 may constitute a flat surface.

The second housing 16 has a contact portion 163
A ring-shaped flange 164 protruding outward is formed on the outer peripheral portion near the base end of. This flange 1
Reference numeral 64 designates a position with respect to the housing 5 in a state in which the base end thereof abuts on the distal end of the housing 5 in a state of being mounted on the housing 5 described later.

A concave portion 165 is formed in the outer peripheral portion of the second housing 16, and a test paper fixing portion 17 on which a disk-shaped test paper 18 is set is mounted in the concave portion 165.

The blood introduction guide 1 protruding toward the inner cavity 161 is provided on the inner peripheral surface of the second housing 16.
66 are formed. This blood introduction guide 166
It has a function of receiving blood (sample) flowing into the lumen 161 from the distal end opening 162 after the fingertip puncture.

In such a chip 13, a blood passage 19 communicating between the inner cavity 161 of the second housing 16 and the outside is formed through the second housing 16 and the test paper fixing portion 17. The blood passage 19 is a flow passage for guiding blood obtained by puncturing to the test paper 18, and has a passage opening 191 opened to the inner cavity 161 and a passage opening 192 opened to the outside of the chip 13. ing. The passage opening 192 is located at the center of the test paper 18.

The blood introduction guide 166 is formed near the passage opening 191. For this reason, the blood received by the blood introduction guide 166 efficiently passes through the passage opening 1.
The blood is guided from 91 to the blood passage 19. This blood reaches the passage opening 192 by capillary action, and the blood reaches the passage opening 192.
Is supplied to the central portion of the test paper 18 installed so as to close the surface, and develops radially.

The test paper 18 has a reagent supported on a carrier capable of absorbing and developing blood.

Examples of the carrier include a sheet-like porous material such as a nonwoven fabric, a woven fabric, and a stretched sheet.
The porous body preferably has hydrophilicity.

The reagent carried on the carrier is appropriately determined depending on the component to be measured in the blood (sample). For example, in the case of blood glucose measurement, glucose oxidase (GOD)
And peroxidase (POD), for example, 4-aminoantipyrine, N-ethyl N- (2-hydroxy-3-
A color-forming agent (color-forming reagent) such as sulfopropyl) -m-toluidine; and those which react with blood components such as, for example, ascorbate oxidase, alcohol oxidase, and cholesterol oxidase, depending on the components to be measured. And the same coloring agent (coloring reagent). Further, a buffer such as a phosphate buffer may be further contained. Needless to say, the types and components of the reagents are not limited to these.

Such a chip 13 is connected to the main body 2 described above.
Is removably attached (fitted) to the housing 5 (fitting portion 53) through the opening 212 of.

As shown in FIGS. 4 and 5, the housing 5 is formed of a bottomed cylindrical member having a wall 51 as a bottom, and a lumen (storage space) 52 is formed inside the housing. ing. A fitting portion 53 whose inner diameter is reduced in accordance with the shape of the outer periphery of the chip 13 is formed on the distal end side of the housing 5. The chip 13 is inserted into the fitting portion 53 and fitted (fixed). In FIGS. 4 and 5,
To facilitate understanding of the description, the structure of the chip 13 is simplified.

An air passage 54 is formed on the side of the housing 5 for communicating the lumen 52 with the outside.
Is connected to the pump 8 via a tube 81.
The air in the lumen 52 is supplied to the air passage 54 and the tube 81.
The inside of the cavity 52 (including the inside of the tube 13) is depressurized.

As shown in FIG. 6, one end of a tube 82 is connected to the middle of the tube 81, and the other end of the tube 82 is open to the outside of the main body 2. The tube 82 has flexibility and can be made of, for example, the same material as the tube 81.

In the middle of the tube 82, an electromagnetic valve 26 for opening and closing (opening / closing) the flow path is provided.

When the solenoid valve 26 is closed (in the closed state), the reduced pressure state of the lumen 52 (including the inside of the tube 13) is maintained, and when the solenoid valve 26 is opened (when it is opened). A tube 82 in the lumen portion 52 in the decompressed state.
Air (atmosphere) from outside through the air passage 81 and the ventilation path 54
Is introduced, and the reduced pressure state is released or alleviated.

Therefore, the tube (flow path) 81,
The 82 and the electromagnetic valve 26 constitute a decompression releasing unit.

As shown in FIGS. 5 and 6, a hole 511 is formed in the wall portion 51 of the housing 5 at a substantially central portion thereof. A thin tube 65 having an orifice (passage) 651 formed therein is provided in the hole 511. Through the orifice 651, air flows between the lumen 52 provided on both sides of the thin tube 65 and a variable volume chamber 631 described later.

A ring-shaped seal ring (sealing member) 55 is fitted to the end of the housing 5. Thereby, when the chip 13 is mounted on the housing 5, the chip 1
The base end of the third flange 164 and the seal ring 55 are in contact with each other, and the airtightness of the lumen 52 is maintained.

The seal ring 55 is made of an elastic body. Examples of such an elastic body include natural rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, nitrile rubber, chloroprene rubber, butyl rubber, acryl rubber, ethylene-propylene rubber, hydrin rubber, urethane rubber, silicone rubber, and fluorine rubber And various thermoplastic elastomers such as styrene, polyolefin, polyvinyl chloride, polyurethane, polyester, polyamide, polybutadiene, and fluororubber.

The housing 5 has a ring-shaped flange 56 protruding outward on the outer periphery of the base end thereof, and a cylindrical projection 59 formed at the base end thereof.

The puncturing means 4 is housed in the inner cavity 52 on the base end side of the fitting portion 53 of the housing 5. The puncture means 4 moves the puncture needle 14 attached to it in the distal direction, and punctures the surface of the fingertip with the cutting edge of the needle body 141.

The puncturing means 4 includes a plunger 41 and a coil spring (urging member) for urging the plunger 41 in the distal direction.
And a coil spring (biasing member) 43 for biasing the plunger 41 in the proximal direction.

At the tip of the plunger 41, a cup-shaped needle holder 411 is provided. This needle holder 411
, The reduced diameter portion 143 of the puncture needle 14 is detachably fitted. At the base end of the plunger 41, an elastically deformable elastic piece 412 having a protruding locking portion 413 at the distal end is provided.

In a state before the tip 13 is mounted on the housing 5, that is, before the puncture needle 14 is mounted on the plunger 41 (see FIG. 4), the locking portion 413 is moved by the elastic force of the elastic piece 412. 3, which is urged upward in the middle to abut the inner peripheral surface of the housing 5. On the other hand, when the tip 13 is mounted on the housing 5, that is, when the puncture needle 14 is mounted on the plunger 41 (see FIG. 5), the locking portion 413 has an opening formed so as to pass through the inside and outside of the housing 5. 57, which locks into its edge. Thereby, the movement of the plunger 41 in the tip direction is restricted. The opening 57 is closed by a flat sealing member (sealing member) 58, and the airtightness of the lumen 52 is maintained. The seal member 58 can be made of the same material as the seal ring 55.

A coil spring (spring for puncturing) 42 is installed on the base end side of the plunger 41, and both ends thereof are
It is in contact with plunger 41 and wall 51. on the other hand,
The coil spring (push-back spring) 43 includes a plunger 41.
And both ends thereof are in contact with the plunger 41 and the fitting portion 53, respectively.

As shown in FIGS. 4 and 5, on the outside of the housing 5, an unlocking portion 413 can move the locking portion 413 into the inner cavity 52 (in the direction of the arrow in the drawing). A member 217 is provided. This locking release member 2
Reference numeral 17 moves in conjunction with the pressing of the operation button 216 described above.

When the locking portion 413 is locked in the opening 57, the coil spring 42 is in a compressed state and urges the plunger 41 in the distal direction. By pressing the operation button 216, the unlocking member 217 is moved in the direction of the arrow in FIG.
When the locking state of the locking portion 413 is released, the coil spring 42 is released.
Is extended to move the plunger 41 in the distal direction, and the cutting edge of the needle 141 pierces the surface (skin) of the fingertip.

On the other hand, at this time, the coil spring 43 is compressed and urges the plunger 41 in the proximal direction, that is, tries to push the plunger 41 back in the proximal direction. afterwards,
The plunger 41 performs a damping movement, and stops at a position where the elastic force of the coil spring 42 and the elastic force of the coil spring 43 are balanced.

When the plunger 41 is stationary, the cutting edge of the needle 141 is housed in the tip 13.

At the base end side of the housing 5, a chip retracting mechanism 6 is provided. The chip retracting mechanism 6 moves the housing 5 and the chip 13 attached thereto in a direction away from the fingertip 200 (base end direction).

As shown in FIGS. 6 to 11, the tip retreat mechanism 6 has a main body 61, a seal ring 64, and a thin tube 65.

The main body 61 is formed of a bottomed cylindrical member having a wall 62 as a bottom, and has a lumen 63 formed therein. The proximal end side of the housing 5 is inserted into the lumen 63.

At the tip of the main body 61, a ring-shaped convex portion 611 protruding toward the center thereof is formed. In the state before the tip retreat mechanism 6 is operated, the protrusion 611
And the distal end of the flange 56 are in contact with each other. Thereby, the movement of the housing 5 in the distal direction is restricted. That is, it is possible to prevent the housing 5 from falling out of the main body 61.

At this time, the tip of the contact portion 163 is
It is almost the same position as the finger contact surface 31 or the finger contact surface 3
1 (see FIG. 6). Thus, when the fingertip 200 is brought into contact with the finger contact portion 3, the surface of the fingertip 200 is reliably brought into contact with the contact portion 163, and the tip opening 162 can be closed.

The wall portion 62 has a recess 621 having a circular cross section at a substantially central portion thereof. The diameter of the concave portion 621 is set substantially equal to the outer diameter of the convex portion 59, and the convex portion 59 is inserted into the concave portion 621. The outer diameter of the flange 56 is set substantially equal to the inner diameter of the main body 61. With such a configuration, regardless of the axial position of the housing 5, for example, a shift in the left-right direction in the figure (a shift between the center of the housing 5 and the main body 61) can be more reliably prevented. .

The outer periphery of the projection 59, that is, the housing 5
A ring-shaped seal ring 64 is provided between the base end of the wall portion 62 and the surface 622 on the distal end side of the wall portion 62. The seal ring 64 is in airtight contact with each of the base end of the housing 5 and the surface 622. Thus, an airtight variable volume chamber (decompression chamber) 631 is defined in a region surrounded by the seal ring 64, the base end of the housing 5, the surface 622, and the inner surface of the recess 621.

The seal ring 64 is made of an elastic material and operates the tip retracting mechanism 6 (the state shown in FIG. 9).
Then, the housing 5 is urged in the distal direction by the elastic force. That is, the seal ring 64 also functions as an urging means. As such an elastic body, the same material as the seal ring 55 and the like can be used.

The thin tube 65 is formed of a cylindrical member, and has an orifice (passage) 651 formed therein. The orifice 651 is provided in the lumen 5 of the housing 5.
2 and the variable volume chamber 631 are communicated with each other. Such orifice 6
The diameter of 51 is not particularly limited.
It is preferably about 0.3 mm. Orifice 651
Is within the above range, a necessary and sufficient air passage (flow) resistance can be obtained.

By adjusting the diameter of the orifice 651, the start timing of the operation of the pump 8 and the operation of the tip retreat mechanism 6 can be adjusted.

Note that the thin tube 65 is not limited to the one shown in the figure, and the number of the thin tube 65 may be set as required.
There may be more than one.

In such a chip retracting mechanism 6, when the fingertip 200 is brought into contact with the contact portion 163 and the pump 8 is operated with the distal end opening 162 sealed, first, the inner cavity 52
(Including the inside of the chip 13) is decompressed, and the air in the variable volume chamber 631 flows through the orifice 651 into the lumen 5.
2 and the pressure in the variable volume chamber 631 is started.
Since the air passage resistance of the orifice 651 is high, the volume of the variable volume chamber 631 gradually decreases, and the housing 5 and the chip 13 mounted thereon move gradually in the direction away from the fingertip 200.

Eventually, the base end 591 of the convex portion 59 and the concave portion 62
When the bottom surface of the housing 1 comes into contact with the housing 5, the movement of the housing 5 and the chip 13 mounted thereon toward the base end is stopped (see FIG. 9). Therefore, by adjusting the length of the protrusion 59 in the axial direction, it is possible to prevent the chip 13 from being unnecessarily separated from the fingertip 200. That is, the chip 1 is formed by the convex portion 59 and the bottom surface of the concave portion 621 abutting thereon.
Means (moving distance defining means) for defining the moving distance (maximum evacuation distance) from the third fingertip 200 is configured.

The separation distance between the chip 13 and the fingertip 200 (the maximum retreat distance of the chip 13) is not particularly limited, but is preferably, for example, about 0.2 to 2.5 mm, and 0.5 to 2.5 mm. More preferably, it is about 1.5 mm. By setting the separation distance within the above range, a sufficient amount of blood can be secured more reliably and in a shorter time. In addition, it is possible to more reliably prevent the fingertip 200 from coming off the tip opening 162.

The tip retracting mechanism 6 operates following the operation of the pump 8. That is, the tip retracting mechanism 6
Reduces the pressure in the inner cavity 52 by the pump 8 and
After sucking the fingertip 200 at 62, the tip 13 is gradually retracted (moved) in the proximal direction. For this reason, the tip retracting mechanism 6 is configured to move the puncture site 2 of the fingertip 200.
While maintaining 10 in a reduced pressure state, the chip 13 is
Can be separated from.

The tip retracting mechanism 6 includes a pump 8
It operates using the decompression force generated by. In other words, the pump (decompression means) 8 can be said to be one of the components of the chip retracting mechanism 6.

Since such a chip retracting mechanism 6 does not require the addition of another driving source, it is advantageous in reducing the size, weight and manufacturing cost of the component measuring device 1.

In the component measuring device 1, as shown in FIG. 7, when the fingertip 200 is pressed against the finger contact portion 3, the surface of the fingertip 200 comes into contact with the tip of the contact portion 163. Capillaries around the puncture site 210 are compressed by the tip of the portion 163, but the puncture site 21 of the fingertip 200 is compressed.
Since the tip 13 can be separated from the fingertip 200 while maintaining the pressure 0 at a reduced pressure, the capillaries around the puncture site 210 that have been pressed by the tip of the contact portion 163 are opened, and the blood 220 becomes more permeable. The blood is sucked out of the puncture site 210 surely and in a short time, and a sufficient and necessary blood volume for measuring the glucose amount can be secured.

The operating state of the chip retracting mechanism 6 (FIG. 9)
), The housing 5 moves in the proximal direction,
The seal ring 64 is in a compressed state. As described above, since the seal ring 64 is made of an elastic body, the seal 5 urges the housing 5 in the distal direction in the state shown in FIG. Therefore, when the solenoid valve 26 is opened to release the reduced pressure state, the seal ring 64 returns to the substantially original shape by its own elastic force, and moves the housing 5 toward the distal end (see FIGS. 10 and 11). At this time, the housing 5
The distal end of the flange 56 abuts on the base end of the convex portion 611 of the main body 61, and further movement in the distal direction is restricted (see FIG. 11). That is, the housing 5 and the chip 13 mounted thereon return to the position before the operation of the chip retreat mechanism 6.

Next, the operation of each part and the control operation of the control means when performing puncture, blood collection, development and blood sugar level measurement using the component measuring apparatus 1 will be described with reference to the flowcharts shown in FIGS. This will be described with reference to FIG.

[1] First, the lid 20 is opened and the chip 1
3 is inserted into the fitting portion 53 of the housing 5 through the opening 212 of the main body 2, and the reduced diameter portion 143 of the puncture needle 14 is fitted to the needle holder 411 (see FIGS. 2 and 4).

When the tip 13 is further pushed in in the proximal direction, the plunger 41 is pressed against the urging force of the coil spring 42.
Moves in the proximal direction. The locking portion 413 includes an elastic piece 412.
Is pressed by the resilient force of the above and is in contact with the inner peripheral surface of the lumen portion 52. When the locking portion 413 comes to the position of the opening 57, it is inserted into the opening 57 (see FIG. 5). As a result, even if the pressing force in the proximal direction by the tip 13 is released, the locking portion 4
13 is locked in the opening 57, and the movement of the plunger 41 in the distal direction is restricted. At this time, the coil spring 42 is in a compressed state. In this state, preparation for puncturing by the puncturing means 4 and preparation for blood (sample) collection are completed.

[2] Next, a power switch (not shown) is turned on. Thereby, each part of the component measuring device 1 is activated and becomes in a measurable state. Note that the solenoid valve 26 is closed.

[3] Next, the fingertip (finger) 2
Press 00. Thereby, the contact portion 1 of the chip 13
The fingertip 200 is crimped to 63. At this time, the tip opening 162 is closed with the fingertip 200 so that air leakage is reduced as much as possible (see FIG. 6).

Here, as described above, the component measuring device 1
Can rise up by its own weight even if it falls down, so that the component measuring device 1 can always be used in an appropriate posture (vertical orientation).

[4] Next, the operation button 216 is pressed to puncture the surface of the fingertip 200 (step S101 in FIG. 13).

When the operation button 216 is pressed, the lock release member 217 connected to the operation button 216 moves to the left in FIG. As a result, the lock release member 217 comes into contact with the lock portion 413 and pushes it back toward the inner cavity 52. As a result, the engagement of the engagement portion 413 is released, and the plunger 41 moves in the distal direction by the elastic force of the compressed coil spring 42, the needle body 141 projects from the distal end opening 162, and punctures the surface of the fingertip 200. (See FIG. 7). Needle 1
Bleeding occurs from the puncture site 210 due to 41.

When the operation button 216 is pressed, the operation switch (not shown) of the pump 8 is turned on almost simultaneously.

[5] After the needle body 141 punctures the fingertip 200, the coil spring 43 pushes the plunger 41 back in the proximal direction. The plunger 41 stops at a position where the elastic force of the coil spring 42 and the elastic force of the coil spring 43 are balanced through the damping movement (see FIG. 8). At this time, the cutting edge of the needle 141 is housed in the tip 13. in this way,
The cutting edge of the needle 141 does not protrude from the tip opening 162 except at the time of puncturing, so that it does not injure the skin or the like accidentally, can prevent infection, and is highly safe.

[6] When the operation switch of the pump 8 is turned on, the control means starts the operation of the pump 8 (step S102 in FIG. 13).

That is, almost at the same time as the operation [4], the pump 8 operates, and the suction of the air in the lumen 52 of the housing 5 is started. As a result, the pressure of the lumen 52 (including the inside of the chip 13) is reduced, and the pressure is reduced.

At this time, the puncture site 210 of the fingertip 200 by the needle 141 is also in a reduced pressure state. However, in this state, the fingertip 200 located inside the contact portion 163 (tip opening 162) rises toward the inside of the chip 13 like a hill, and the puncture site 210 where the tip of the contact portion 163 is in contact. The capillaries are squeezed in the surrounding area.

[7] Further, the lumen 5 by the pump 8
When the suction of 2 is continued, the air in the variable volume chamber 631
Through the orifice 651, the gas gradually flows into the lumen 52, and the volume of the variable volume chamber 631 gradually decreases.
As a result, the housing 5 and the chip 13 attached thereto move in the proximal direction, that is, the fingertip 200
It gradually starts moving in the direction away from.

At this time, since the decompressed state of the inner cavity 52 and the puncture site 210 of the fingertip 200 is maintained, the fingertip 200 does not come off from the distal end opening 162. Further, even if the chip 13 moves in the direction away from the fingertip 200, the fingertip 200 does not move following the chip 13 because it is in contact with the finger rest 3. Therefore, the chip 13 is securely separated from the fingertip 200.

[0138] When the tip 13 is separated from the fingertip 200, the capillaries around the puncture site 210, which have been pressed by the tip of the contact portion 163, are gradually released, and blood 220 is sucked out from the puncture site 210. (See FIG. 9). That is, bleeding is promoted as compared with a case where the fingertip 200 and the chip 13 are not separated from each other, and a necessary blood volume can be secured in a short time.

The minimum pressure generated by the pump 8 is preferably, for example, about 100 to 400 mmHg.

Eventually, the base end 591 of the convex portion 59 and the concave portion 62
1 contacts the bottom surface. As a result, the movement of the housing 5 and the tip 13 attached thereto in the proximal direction is stopped. As described above, since the tip 13 stops when the tip 13 is separated from the fingertip 200 by an appropriate distance, the fingertip 200 does not come off from the distal end opening 162. Therefore, it is possible to more reliably prevent the blood 220 sucked from the puncture site 210 from scattering and contaminating the surroundings, and the safety is high.

As described above, in the component measuring device 1, the puncturing operation and the depressurizing operation are performed almost simultaneously by one pressing of the operation button 216, and the evacuation operation of the tip 13 is performed by the depressurizing force of the pump 8. Is carried out using
Since the decompression releasing operation described later is also started automatically, the operability is extremely good.

[8] By the operation of [7], the puncture site 2
The blood 220 that has been raised in a granular manner on the blood 10 is sucked into the chip 13, and the blood introduction guide 166 formed inside the chip 13.
To the test paper 18 through the blood passage 19,
It is supplied to the center of the test paper 18 and developed radially (see FIG. 3).

As the blood 220 is supplied and spread on the test paper 18, glucose (a component to be measured) in the blood 220 reacts with the reagent carried on the test paper 18, and the test paper 18
Is colored according to the amount of glucose.

On the other hand, after executing the step S102 shown in FIG. 13, the control means 11 drives the measuring means 7 and monitors the coloration of the test paper 18 via the measuring means 7 (monitor).
Then, it is determined whether or not blood has been collected (step S103 in FIG. 13).

In step S103, if the voltage level of the signal input from the light receiving element 72 of the measuring means 7 exceeds a preset threshold value, it is determined that blood has been collected, and If the voltage level is below the threshold, it is determined that blood has not been collected.

The threshold value is sufficiently higher than the voltage level of the signal before the test paper 18 is colored, and
The value is set to a value sufficiently smaller than the voltage level of the signal when the color is displayed.

If it is determined in step S103 that no blood has been collected, it is determined whether or not the time is up (step S104 in FIG. 13).

In step S104, if it is determined that the time is not up, the process returns to step S103, and steps S103 and subsequent steps are executed again. If it is determined that the time is up, an error process is performed (see FIG. 13). Step S105).

In step S105, the pump 8 is stopped, the solenoid valve 26 is opened to release the reduced pressure state, and a display indicating an error (error display) is displayed on the display unit 12.

The operator (user) can grasp from the error display that the error is an error (there is a problem).

The operation when the solenoid valve 26 is opened will be described later in detail. If it is determined in step S103 that blood has been collected, the pump 8 is stopped (step S106 in FIG. 13).

Next, the solenoid valve 26 is opened to release the reduced pressure state (step S107 in FIG. 13).

When the solenoid valve 26 is opened, the tubes 82, 81
Outside air (atmosphere) flows into the lumen portion 52 (including inside the chip 13) and the puncture site 210 via the ventilation path 54, and the lumen portion 52 (including inside the chip 13) and the puncture site 210 become large. It returns to the atmospheric pressure (see FIG. 10).

Further, the seal ring 64 returns to a substantially original shape by its own elastic force, and moves the housing 5 toward the distal end (see FIGS. 10 and 11). At this time, the tip of the flange 56 of the housing 5 is
And is restricted from moving further in the distal direction (see FIG. 11).

When it is confirmed that the feeling of suction around the puncture site 210 of the fingertip 200 disappears and the pressure returns to the atmospheric pressure, the contact portion 163 of the chip 13 is separated from the fingertip 200.

[9] After executing the step S107 shown in FIG. 13, the control means 11 measures the degree of coloration of the test paper 18 by the measuring means 7, performs an arithmetic process based on the obtained data, Correction such as correction calculation and hematocrit value correction calculation is performed to quantify the blood sugar level (step S108 in FIG. 13).

In this case, since the decompressed state of the inner cavity 52 (including the inside of the chip 13), that is, the depressurized state of the storage space for the test paper 18, has been released, the glucose (the component to be measured) in the blood 220 has been released. ) And the components (eg, oxygen, carbon dioxide, water vapor, etc.) in the atmosphere necessary for the reaction between the reagent carried on the test paper 18 are sufficiently supplied, whereby the blood glucose level can be accurately measured.

Next, the calculated blood sugar level is displayed on the display unit 1.
2 (step S109 in FIG. 13).

As a result, the blood sugar level can be grasped. After the pressure reduction state is released, the electromagnetic valve 26 is closed again in preparation for the next measurement.

As described above, this component measuring device 1
According to the method, a sufficient amount of blood necessary and sufficient for measurement can be collected in a short time, and a blood sugar level (amount of a predetermined component in blood) can be accurately and reliably measured.

In particular, since the component measuring device 1 rises by its own weight even if it falls down, the component measuring device 1 can always be used in an appropriate posture (vertical orientation),
Each part of the component measuring device 1 operates properly and reliably, and the blood glucose level can be measured more accurately and reliably.

Further, even if the patient moves during the measurement,
The component measuring device 1 follows the movement of the fingertip 200 of the patient, thereby preventing the fingertip 200 from coming off the tip opening 162 of the chip 13. Thereby, the blood sugar level can be accurately and reliably measured in a shorter time.

Further, since the test paper 18 is provided on the chip 13, puncturing, blood collection, development on the test paper 18, and measurement (quantification of components) can be performed continuously.
Blood glucose measurement (component measurement) can be performed easily and in a short time.

Further, the preparation operation at the time of use is easy, and therefore, it is advantageous when the device is used regularly or repeatedly.

In addition, accidents such as accidental puncturing of the living body surface after puncturing once are prevented, and the safety is high. Moreover, since the puncture needle 14 is not directly visible, fear of puncturing is reduced.

As described above, this component measuring device 1
It is suitable for use when the patient himself measures his or her blood glucose level.

The component measuring device 1 has a simple structure, is small and lightweight, is inexpensive, and is suitable for mass production.

As described above, the component measuring apparatus of the present invention has been described based on the illustrated embodiment. However, the present invention is not limited to this. For example, the configuration of each part can exhibit the same function. Any configuration can be used.

Further, in the above embodiment, blood was used as a representative example of the body fluid to be collected. However, in the present invention, the body fluid to be collected is not limited to this. Good.

In the above embodiment, glucose (blood sugar level) is described as a representative component to be measured. However, in the present invention, the component to be measured is not limited to this. For example, protein, cholesterol, Inorganic ions such as uric acid, creatinine, alcohol, and sodium may be used.

In the above embodiment, the measuring means measures the amount of the predetermined component. However, in the present invention, the measuring means may measure the property of the predetermined component. It may measure the amount and properties of a predetermined component.

In the above-described embodiment, a means that serves both as a blood sampling detecting means for detecting blood sampling and a measuring means for measuring the amount of a predetermined component in blood (in the embodiment, this means is referred to as a “measuring means”). However, in the present invention, the blood sampling detecting means and the measuring means may be provided separately.

In the above embodiment, means for optically detecting blood collection is used as the blood collection detecting means. However, the present invention is not limited to this.
Means for electrically detecting may be used.

Further, the component measuring apparatus of the present invention optically measures (colorimetrically measures) the color intensity of the test paper colored by the reaction between the components in blood and the reagent as described above, and converts the measured value into a measured value. The present invention is not limited to the conversion and display. For example, a potential change generated according to the amount of the component in the sample may be electrically measured, converted to a measured value, and displayed.

Further, in the above-described embodiment, the reduced pressure state is released before the measurement, but in the present invention, the reduced pressure state may be relaxed before the measurement.

Further, in the present invention, the operations of the pressure reducing means and the chip retreating mechanism may be started manually or automatically, respectively. In the latter case, a sensor or the like configured to magnetically sense the movement of the puncture needle in the tip direction at the time of puncturing the fingertip is installed near the side position of the fitting portion of the housing, and information of this sensor is provided. , The pressure reducing means and the chip retracting mechanism can be operated. Further, in the present invention, the chip retracting mechanism may be omitted.

[0177]

As described above, according to the present invention, it is possible to fall or roll, and then to return to its original state naturally (for example, it is possible to get up by its own weight) It is always structured like
The component measuring device can be used in a proper posture,
Thereby, each part of the component measuring device operates properly and reliably, and a predetermined component in a body fluid (for example, blood) can be reliably measured, and the measurement accuracy can be improved.

Further, even if the user (patient) moves during the measurement, the component measuring device follows the movement of the epidermis (for example, a finger or the like) to which the user has been applied, whereby the contact portion It can be prevented that the epidermis comes off from the predetermined part. Thus, a predetermined component in a bodily fluid (eg, blood or the like) can be accurately and reliably measured in a shorter time.

When the test paper is provided on the chip,
Puncture, collection of body fluids (eg, blood, etc.), development on test paper, and measurement (quantification of components) can be performed continuously, and component measurement can be performed easily and in a short time.

Further, since the preparation operation at the time of use is easy, it is advantageous when the device is used regularly or repeatedly.

Also, accidents such as accidental puncturing of the living body surface after puncturing once are prevented, and the safety is high. Moreover, since the puncture needle is not directly visible, fear of puncturing is reduced.

As described above, the component measuring apparatus of the present invention is suitable for use when a patient himself / herself measures a blood sugar level or the like.

The component measuring apparatus of the present invention has a simple structure, is small and lightweight, is inexpensive, and is suitable for mass production.

[Brief description of the drawings]

FIG. 1 is a front view showing an embodiment (in a state where a lid is closed) of a component measuring apparatus according to the present invention.

FIG. 2 is a side view showing the component measuring device shown in FIG. 1 (with a lid opened).

FIG. 3 is a longitudinal sectional view showing a configuration example of a chip used in the present invention.

FIG. 4 is a longitudinal sectional view showing a configuration example of a puncturing means and a housing containing the puncturing means of the component measuring apparatus shown in FIG. 1 (a state before a chip is mounted on the housing).

5 is a longitudinal sectional view showing a configuration example of a puncturing means and a housing containing the puncturing means of the component measuring device shown in FIG. 1 (in a state where a chip is mounted on the housing).

6 is a longitudinal sectional view showing a configuration example of a main part in the component measuring device shown in FIG. 1 (a state before the puncturing means is operated).

FIG. 7 is a longitudinal sectional view showing a configuration example of a main part in the component measuring device shown in FIG. 1 (when the puncturing means is operating).

8 is a longitudinal sectional view showing a configuration example of a main part in the component measuring device shown in FIG. 1 (when the pressure reducing means is operated).

FIG. 9 is a longitudinal sectional view showing a configuration example of a main part of the component measuring device shown in FIG. 1 (when the tip retracting mechanism is operated).

FIG. 10 is a longitudinal sectional view showing a configuration example of a main part in the component measuring device shown in FIG. 1 (when the decompression releasing means is operated).

11 is a longitudinal sectional view (final state) showing a configuration example of a main part in the component measuring device shown in FIG. 1.

12 is a block diagram showing a circuit configuration of the component measuring device shown in FIG.

13 is a flowchart showing a control operation (partially including an operation of an operator) of a control unit of the component measuring device shown in FIG.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Component measuring apparatus 2 Main body 20 Lid 211 Wall part 212 Opening 213 Axis 214, 215 Depression 216 Operation button 217 Lock release member 218 Grip part 219 Display window 23 Weight 3 Finger contact part 31 Finger contact surface 4 Puncturing means 41 Plunger 411 Needle holder 412 Elastic piece 413 Locking part 42 Coil spring 43 Coil spring 5 Housing 51 Wall part 511 Hole 52 Lumen part 53 Fitting part 54 Ventilation path 55 Seal ring 56 Flange 57 Opening 58 Seal member 59 Convex part 591 Base end 6 Tip retreat Mechanism 61 Body 611 Convex part 62 Wall part 621 Concave part 622 Surface 63 Lumen part 631 Variable volume chamber 64 Seal ring 65 Small tube 651 Orifice 7 Measuring means 71 Light emitting element 72 Light receiving element 8 Pump 81, 82 Tube 9 Battery 11 Control means 12 Display 3 Tip 14 Puncture Needle 141 Needle Body 142 Hub 143 Reduced Diameter Part 15 First Housing 151 Inner Peripheral Surface 152 Lumen 153 Wall 154 Hole 16 Second Housing 161 Lumen 162 Tip Opening 163 Contact Part 164 Flange 165 recess 166 blood introduction guide 17 test paper fixing part 18 test paper 19 blood passage 191 passage opening 192 passage opening 24 amplifier 25 A / D converter 26 solenoid valve 200 fingertip 210 puncture site 220 blood S101 to S109 Step

Claims (7)

[Claims] 1. A component measuring device for collecting a body fluid through an epidermis and measuring a component of the body fluid, comprising a contact portion for applying the epidermis on an upper portion, and capable of falling down or rolling. And a component measuring device that is configured to be able to return to its original state naturally thereafter. 2. A component measuring device for collecting a body fluid through an epidermis and measuring a component of the body fluid, wherein the contact portion is provided on an upper portion and applies the epidermis, and the epidermis is applied to the applicator. A space that is hermetically sealed, a pressure reducing unit that reduces the pressure in the space, and an amount and / or amount of a predetermined component in a body fluid collected in the space.
Or a measuring means for measuring a property, wherein the component measuring device is configured to be capable of falling or rolling, and to be able to return to its original state naturally thereafter. 3. A component measuring device for collecting a body fluid through an epidermis and measuring a component of the body fluid, comprising: a puncture needle; a contact portion provided on an upper portion and adapted to contact the epidermis to be punctured; Puncturing means for operating the puncture needle so as to puncture the epidermis applied to the skin, decompression means for reducing the puncture site of the epidermis by the puncture needle together with the storage space for the puncture needle, and sampling from the puncture site Measuring means for measuring the amount and / or property of the predetermined component in the obtained body fluid, capable of falling down or rolling down, and thereafter being able to return to the original state naturally. A component measuring device, comprising: 4. The component measuring device has a housing that holds a tip provided with the puncture needle, and houses a puncturing means, and the decompression means puts the storage space in the housing into a decompressed state. Item 4. The component measuring device according to Item 3. 5. The component measuring device according to claim 1, wherein an outer surface of a bottom portion of the component measuring device has an outwardly convex curved surface. 6. The component is arranged such that the center of gravity of the component measuring device is located on the bottom side from the center thereof.
6. The component measuring device according to any one of items 5 to 5. 7. The component measuring device according to claim 1, wherein a weight is provided near a bottom of the component measuring device.