JP2000053524A - Cosmetic composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic which improves the greasy touch peculiar to oily raw materials and is excellent in the conditioning effect, e.g. application feeling such as good spread, agreeableness, smoothness or the like as for skin, giving smoothness and pliability, fine combability or the like to hair. SOLUTION: This cosmetic composition is obtained by including an N-long chain acyl neutral amino acid ester (component A) in which a straight or branched chain of saturated or unsaturated acyl group has a carbon atom number of 6-22 and hydrocarbon group constructing its alcohol part is a straight or branched chain of saturated or unsaturated hydrocarbon group with a carbon atom number of 1-10 or/and an N-long chain acyl acidic amino acid diester (component B) in which a straight or branched chain of saturated or unsaturated acyl group has a carbon atom number of 6-22 and hydrocarbon group constructing its alcohol part is a straight or branched chain of saturated or unsaturated hydrocarbon group with a carbon atom numbers of 1-10, and a cosmetic oily raw material (component C) as active ingredients.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a cosmetic composition, and more particularly, to an N-long-chain acyl neutral amino acid ester and / or
And a N-long-chain acyl acidic amino acid diester and an oily raw material for cosmetics as active ingredients.

[0002]

2. Description of the Related Art In cosmetics, oil-based raw materials are widely used from the viewpoints of maintaining a binder, an emollient, and a dosage form of components incorporated in the cosmetics, and imparting conditioning properties to hair. Conventionally, mineral oils such as liquid paraffin and fatty acid esters such as isopropyl myristate and isopropyl palmitate have been widely used as oily raw materials for cosmetics.

[0003] However, these oily raw materials have a sticky feeling, and have good spreadability and familiarity with the skin.
There is a problem that the feeling of use such as smoothness is impaired. Also, in the conditioning effect on hair,
It was not enough.

[0004]

SUMMARY OF THE INVENTION Under the background of the prior art described in the preceding paragraph, an object of the present invention is to improve the sticky feeling peculiar to oily raw materials, to provide a feeling of use such as stretching, familiarity, smoothness to the skin, and hair. An object of the present invention is to provide a cosmetic which is excellent in conditioning effects such as imparting smoothness, softness and combability to the skin.

[0005]

Means for Solving the Problems The present inventors have made intensive studies to achieve the object described in the preceding paragraph, and have found that a specific N-long-chain acyl neutral or acidic amino acid ester is used in combination with an oily raw material for cosmetics. Thus, the inventors have found that the above problems can be solved, and have completed the present invention based on such findings.

[0006] That is, the present invention provides a method for preparing a compound having 6 to 22 carbon atoms.
An ester of an N-long-chain acyl-neutral amino acid having a linear or branched saturated or unsaturated acyl group, wherein the hydrocarbon group constituting the alcohol moiety has 1 to 1 carbon atoms.
N-long-chain acyl-neutral amino acid ester which is 10 straight-chain or branched-chain saturated or unsaturated hydrocarbon groups (component A)
And / or a diester of an N-long-chain acyl acidic amino acid having a linear or branched saturated or unsaturated acyl group having 6 to 22 carbon atoms, wherein the hydrocarbon group constituting the alcohol site is a carbon atom. Contains, as active ingredients, diesters of N-long-chain acyl acidic amino acids (component B) which are linear or branched saturated or unsaturated hydrocarbon groups of formulas 1 to 10 (component B) and oily raw materials for cosmetics (component C). And a cosmetic composition.

Here, both the ester of component A and the diester of component B are so-called oily raw materials for cosmetics (broadly defined).
In the present invention, the cosmetic oily raw material of the component C in the present invention is a cosmetic oily raw material in a narrow sense except for the cosmetic oily raw materials of the components A and B.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail.

First, the N-long-chain acyl neutral or acidic amino acid ester, which is one of the essential components of the cosmetic composition of the present invention, will be described.

First, the N-long-chain acyl neutral amino acid ester (component A) according to the present invention will be described in detail.

In the present invention, the long-chain acyl group of the N-long-chain acyl neutral amino acid ester has 6 to 2 carbon atoms.
2 linear or branched, saturated or unsaturated, for example, capric acid, lauric acid, myristic acid,
Palmitic acid, stearic acid, behenic acid, linoleic acid, linoleic acid, oleic acid, isostearic acid, 2
And acyl groups which can be derived from ethylhexanoic acid, coconut oil fatty acid, tallow fatty acid, hardened tallow fatty acid and the like. Preferred acyl groups include caproyl, lauroyl, myristyl, palmitoyl,
Examples include a stearoyl group, a behenoyl group, a coconut oil fatty acid acyl group (cocoyl group), a hardened tallow fatty acid acyl group, and a palm kernel oil fatty acid acyl group.

The neutral amino acids constituting the neutral amino acid site include glycine, alanine, valine, leucine, isoleucine, serine, threonine, proline, β-alanine, aminobutyric acid, sarcosine, N-methyl-β-alanine and the like. Neutral amino acids. Preferably, glycine, alanine, β-alanine, α-aminobutyric acid, γ-
Aminobutyric acid, sarcosine and N-methyl-β-alanine, particularly preferred are sarcosine, alanine, glycine and N-methyl-β-alanine. These amino acids may be either optically active or racemic.

The hydrocarbon group constituting the alcohol moiety is a branched or straight-chain alkyl or alkenyl group having 1 to 10 carbon atoms, preferably an alkyl group, such as methanol, ethanol, or the like. Propanol, isopropanol, butanol, t-butanol,
Isobutanol, 3-methyl-1-butanol, 2-methyl-1-butanol, fusel oil, pentanol, hexanol, cyclohexanol, octanol, 2-
Examples include hydrocarbon groups that can be derived from ethylhexanol, decanol, and the like. Further, from the viewpoint of feeling of use and the like, a branched or straight-chain alkyl group having 2 to 8 carbon atoms is preferable, and a branched or straight-chain alkyl group having 2 to 5 carbon atoms is more preferable. In addition to the feeling of use and the stability of hydrolysis, a branched alkyl group having 3 to 5 carbon atoms is particularly preferable, and examples thereof include an isopropyl group, a t-butyl group, and an isobutyl group. Among them, the most preferred is an isopropyl group.

A preferred example of the N-long-chain acyl-neutral amino acid ester in the present invention is represented by the following general formula, and examples thereof include those represented by the following general formula (1).

[0015]

Embedded image

(Wherein R¹Is a straight chain having 5 to 21 carbon atoms
Or a branched alkyl or alkenyl group represented by R²Is water
A linear or branched alkyl having 1 to 3 carbon atoms
A group represented by R³Is a hydrogen atom or a straight-chain or
Represents a branched alkyl group, R ⁴Represents 1 to 10 carbon atoms
A branched or straight-chain alkyl or alkenyl group
And m represents an integer of 0 to 2. )

In the general formula (1), an acyl group (R ¹ -CO
-) and Preferred as R ⁴ hydrocarbon groups constituting the alcohol moiety is as described above. Preferred amino acid sites are also as described above.

The N-long-chain acyl-neutral amino acid ester in the present invention can be obtained, for example, by subjecting an N-long-chain acyl-neutral amino acid and an alcohol to heat dehydration condensation esterification under normal pressure or reduced pressure. Further, an azeotropic dehydration-condensation reaction or a transesterification reaction using a solvent such as toluene can also be used. The N-long-chain acyl-neutral amino acid and the alcohol used for the synthesis of such N-long-chain acyl-neutral amino acid ester do not necessarily need to be a single compound. −
It may be a mixture of long-chain acyl neutral amino acids or a mixture of alcohols having different chain lengths.

Incidentally, N-long-chain acyl-neutral amino acids are
For example, it can be produced by a known method such as the so-called Schotten-Baumann reaction in which a long-chain fatty acid halide is reacted with an amino acid in the presence of a basic catalyst (see Japanese Patent Publication No. 51-38681).

Next, the N-long-chain acyl acidic amino acid diester (component B) will be described in detail.

The long-chain acyl group of the N-long-chain acyl acidic amino acid diester in the present invention is the same as the long-chain acyl group of the N-long-chain acyl neutral amino acid ester described above, and the preferred acyl group is also the same. is there.

The acidic amino acids constituting the acidic amino acid site include glutamic acid and aspartic acid. Particularly preferred is glutamic acid. These amino acids may be optically active or racemic.

The hydrocarbon group constituting the ester moiety is the same as that of the N-long-chain acyl neutral amino acid ester described above, and the preferred one is also the same.

In the present invention, preferred examples of the N-long-chain acyl acidic amino acid diester are represented by the following general formula, and include those represented by the following general formula (2).

[0025]

Embedded image

(Wherein, R ⁵ is a branched or straight-chain alkyl or alkenyl group having ^{5 to} 21 carbon atoms, and R ⁶ and R ⁷ are each independently a straight-chain or branched chain having 1 to 10 carbon atoms. A chain alkyl or alkenyl group, and n represents an integer of 0 or 1.)

The N-long-chain acyl acidic amino acid diester in the present invention can be obtained, for example, by subjecting an N-long-chain acyl acidic amino acid and an alcohol to heat dehydration condensation esterification under normal pressure or reduced pressure. In addition, an azeotropic dehydration condensation reaction or a transesterification reaction using toluene or the like as a solvent can also be used. The N-long chain acyl acidic amino acid diester used in the synthesis of such N-long chain acyl acidic amino acid diester does not necessarily need to be a single compound, and N-long chains having different types of acyl groups and acidic amino acids are not necessarily required. It may be a mixture of acyl acidic amino acids or a mixture of alcohols having different chain lengths.

Incidentally, the N-long-chain acyl acidic amino acid is
For example, the so-called Schotten-Baumann reaction in which a long-chain fatty acid halide is reacted with an amino acid in the presence of a basic catalyst (JP-B-46-8865, JP-B-48-35058, and JP-B-5
And the like.

These N-long-chain acylamino acid esters have low irritation to the skin and mucous membranes and are excellent in feeling of use such as good spreadability, familiarity and smoothness to the skin, and thus are particularly useful for cosmetics. It is excellent for use as an oily raw material. In particular, N-long-chain acyl neutral amino acid esters are free from the unpleasant oily feeling and sticky feeling peculiar to oily raw materials, are excellent in a light feeling that is refreshing or smooth, and are suitable for use in cosmetics. Preferred over amino acid diesters.

Next, the oily raw material for cosmetics of the component C will be described. Oily raw materials for cosmetics can be broadly classified into natural, mineral, and synthetic systems.

Examples of natural oil-based raw materials include beeswax, salami beeswax, candelilla wax, carnauba wax, ibitaro, mokuro, rice bran wax, salasimontarou, lanolin, ceresin, squalane, pristane, turpentine oil, eucalyptus oil, terpineol, eucalyptol ,
Olive oil, camellia oil, tea seed oil, sasanqua oil, safflower oil, sunflower oil, soybean oil, cottonseed oil, sesame oil, corn oil, peanut oil, rapeseed oil, rice bran oil, rice germ oil, adlay oil, grape seed oil, almond Oil, jojoba oil, avocado oil, carrot oil, macadamia nut oil, hazelnut oil, meadowfoam oil, shea butter, evening primrose oil, cocoa butter, castor oil, hardened castor oil, linseed oil, coconut oil, palm oil, palm kernel oil, Beef tallow, horse oil, mink oil, cod liver oil, shark liver oil, orange roughy oil, milk fat, egg yolk oil, egg yolk fat oil, powdered fat oil, clove oil, rosehip oil, lavender oil, Roman chamomile oil, rosemary oil, etc. And partially hydrolyzed jojoba oil and oxystearic acid-cured castor Oil, acetic castor oil, partially hydrogenated horse oil, adsorption purified lanolin, liquid lanolin, reduced lanolin, hard lanolin, acetic hard lanolin, acetic acid liquid lanolin.

Examples of the mineral oily raw materials include liquid paraffin, light paraffin, heavy paraffin, volatile paraffin, liquefied petroleum gas, petrolatum, microcrystalline wax and the like.

The synthetic oily raw materials include acetic acid (cetyl lanolyl) ester, triacetyl glyceryl, eicosanyl propionate, lauryl lactate, myristyl lactate, cetyl lactate, octyl dodecyl lactate, diisostearyl malate, polypropylene glycol oligosuccinate succinate, 2-ethylhexyl succinate, stearyl heptanoate, diisopropyl adipate, dibutyl adipate,
Dioctyl adipate, di-2-ethylhexyl adipate, di-2 heptylundecyl adipate, cetyl caprylate, glyceryl tricaprate, cetyl 2-ethylhexanoate, cetostearyl 2-ethylhexanoate, tri2-
Glyceryl ethylhexanoate, pentaerythrit tetra-2-ethylhexanoate, isocetyl octanoate, isostearyl octanoate, ethylene glycol dioctanoate, neopentyl glycol dioctanoate, trimethylolpropane trioctanoate, hexyldecyl dimethyloctanoate, dimethyloctanoic acid Octyldodecyl, isononyl isononanoate, isodecyl isononanoate, isotridecyl isononanoate, isotridecyl dinonanoate,
Propylene glycol dinonanoate, octyl pelargonate, octyl isoperargonate, glycerin tri (caprylate / caproate), neopentyl glycol dicaprate, diisopropyl sebacate, hexyl laurate, isostearyl laurate, glyceryl trilaurate, glyceryl tricocoate Isopropyl myristate, butyl myristate, myristyl myristate, cetyl myristate, isocetyl myristate, isostearyl myristate, octyldodecyl myristate, glyceryl trimmyristate, pentaerythritol tetramyristate, isopropyl palmitate, octyl palmitate , Cetyl palmitate, isocetyl palmitate, 2-ethylhexyl palmitate, octyl isopalmitate Glyceryl triisomyristate, ethyl stearate, octyl stearate, isocetyl stearate, stearyl stearate, hydrogenated castor oil stearate, glyceryl tristearate, batyl stearate, isopropyl isostearate, butyl isostearate, hexyl isostearate, isostearin Isocetyl acid, isostearyl isostearate, hydrogenated castor oil isostearate, octyldodecyl isostearate, batyl isostearate, polyglyceryl monoisostearate, glyceryl tri (isostearate), diglyceryl tri (isostearate), trimethylol tri (isostearate) Propane, tetra (isostearic acid) polyglyceryl, tetra (isostearic acid) polyglyceryl Hydroxystearic acid 2-ethylhexyl, ethyl oleate, decyl oleate, isodecyl oleate, oleyl oleate, oleyl dodecyl oleate, di (oleic acid)
Ethylene glycol, glyceryl tri (oleate),
Octyldodecyl ricinoleate, isodecyl pivalate, isostearyl pivalate, glyceryl tribehenate, octyldodecyl erucate, isopropyl lanolin fatty acid, octyldodecyl lanolin fatty acid, ethyl avocado oil fatty acid, ethyl mink oil fatty acid, dipentaerythrit fatty acid ester, hexa Higher fatty acid esters such as dipentaerythritol oxystearate, di (cholesterol, behenyl, octyldodecyl alcohol) -N-lauroyl-L-glutamate, di (behenyl, octyldodecyl alcohol) -N-lauroyl-L-glutamate , N-lauroyl-
And L-glutamic acid di (phytosteryl-2-octyldodecyl).

As the synthetic oily raw material, a silicone compound can also be used. Silicone compounds include methylpolysiloxane, highly polymerized methylpolysiloxane, methylphenylpolysiloxane, amino-modified silicone, alkyl-modified silicone, epoxy-modified silicone, fluorine-modified silicone, polyether-modified silicone, alcohol-modified silicone, fatty acid-modified silicone, and acrylic. Modified silicones and the like can be mentioned, and usually used for cosmetics have a viscosity of 5 centistokes to 10 centistokes.
One million centistokes.

Methylpolysiloxane and highly polymerized methylpolysiloxane generally have a viscosity of 50 to 10 million cent strokes. In addition, the highly polymerized methylpolysiloxane can be used as an emulsion for easy handling.

A methylphenylpolysiloxane having a viscosity of usually 10 to 1000 centistokes can be used.

Examples of the cyclic polysiloxane include octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclopentasiloxane, methylpolycyclosiloxane and the like.

Examples of the amino-modified silicone include an aminoethylaminopropylsiloxane / dimethylsiloxane copolymer emulsion.

Examples of the ether-modified silicone include dimethylsiloxane / methyl (polyoxyethylene) siloxane copolymer, dimethylsiloxane / methyl (polyoxypropylene) siloxane copolymer, and dimethylsiloxane / methyl (polyoxyethylene) siloxane / methyl ( (Polyoxypropylene) siloxane copolymer and the like.

Other examples include methylhydrogenpolysiloxane, dimethylsiloxane / methylstearoxysiloxane copolymer, dimethylsiloxane / methylcetyloxysiloxane copolymer, tetradecamethylhexasiloxane, trimethylsiloxysilicic acid, octamethyl Examples include trisiloxane, silicone resin, and myristyl silicone.

Further, these can be used after being alkoxy-modified, carboxy-modified, alcohol-modified, fatty acid-modified, fluorine-modified, or epoxy-modified. Further, two or more kinds of silicones can be mixed or used as an emulsion.

Commercially available silicone compounds include KF-96A series and KF-96H series manufactured by Shin-Etsu Chemical Co., Ltd. for dimethylpolysiloxane; and KF-96H series manufactured by Shin-Etsu Chemical Co., Ltd. for methylphenylpolysiloxane. -50, KF-53; Examples of cyclic polysiloxanes include KF-994 and KF-99 manufactured by Shin-Etsu Chemical Co., Ltd.
5; dimethylpolysiloxane and methyl (polyoxyethylene) siloxane copolymers are manufactured by Shin-Etsu Chemical Co., Ltd.
F-351A; KF-7312F manufactured by Shin-Etsu Chemical Co., Ltd. as trimethylsiloxysilicic acid; TSF484 manufactured by Toshiba Silicone Co., Ltd. as methylhydrogenporinsiloxane; Toshiba Silicone Co., Ltd. as amino-modified silicone XF42-B1989 manufactured by Toshiba Silicone Co., Ltd.
SF410; FQF501 manufactured by Toshiba Silicone Co., Ltd. as a fluorine-modified silicone; FZ-3736 manufactured by Nippon Unicar Co., Ltd. as an epoxy-modified silicone;
Nippon Unicar Co., Ltd. as an alkoxy-modified silicone
FZ-3722 manufactured by Nippon Unicar Co., Ltd. FZ-3703 manufactured by Nippon Unicar Co., Ltd., and FZ-3122 manufactured by Nippon Unicar Co., Ltd. are known as silanol-modified silicone.

In the cosmetic composition of the present invention, in addition to the component A and / or the component B and the component C described above,
Various commonly used additives can be added as optional components within a range not to impair the effects of the present invention. Examples include polymeric substances, surfactants, fatty acids, alcohols, polyhydric alcohols, extracts, amino acids, nucleic acids, vitamins, enzymes, anti-inflammatory agents, bactericides, preservatives, antioxidants, ultraviolet absorbers, Standards of cosmetic raw materials such as chelating agents, antiperspirants, pigments, pigments, oxidation dyes, organic and inorganic powders, pH adjusters, pearlizing agents, wetting agents, moisturizers, etc. Raw materials described in the standards, Japanese Pharmacopoeia, and official food additives, and the like.

The cosmetic composition of the present invention may further contain a perfluoropolyether. Such perfluoropolyethers typically have a molecular weight of 500-500.
20,000, and commercially available products include Fomblin HC series manufactured by Ausimont.

The cosmetic composition of the present invention imparts conditioning and styling properties to the hair, adjusts the viscosity of various cosmetics, stabilizes the dosage form, and improves spread during application. A polymer compound may be added for the purpose. Examples of the polymer compound include polyacrylic acid and salts thereof (sodium, potassium, ammonium, triethanolamine, arginine, lysine, etc.), acrylic resin,
Acrylic acid derivatives such as acrylic acid / acrylamide / ethyl acrylate copolymer and salts thereof; polyglutamic acid and salts thereof; polyaspartic acid and salts thereof; hyaluronic acid and salts thereof; alginic acid and salts thereof; alkyl acrylate / methacrylic acid Alkyl acid esters, diacetone, acetone acrylamide, methacrylic acid copolymers and salts thereof, methacrylic acid derivatives such as polymethacrylic acid and salts thereof; vinyl acetate / crotonic acid copolymer, crotonic acid / vinyl acetate / vinyl neodecanoate copolymer Crotonic acid derivatives such as methoxyethylene maleic anhydride copolymer and isobutylene / maleic acid copolymer; carboxymethyl cellulose; carboxyvinyl polymer, chitosan, partially hydrolyzed chitin, chitosa · Dl-pyrrolidone carboxylic acid salt,
Chitin derivatives such as succinylchitosan and hydroxypropylchitosan; dimethyldiallylammonium chloride derivatives such as dimethyldiallylammonium chloride / acrylamide copolymer and polydimethyldimethylmethylenepiperidinium chloride; O- [2-hydroxy-3- (trimethylammonio chloride) ) Cationized cellulose such as propyl] hydroxyethylcellulose and O- [2-hydroxy-3- (lauryldimethylammonio) propyl] hydroxyethylcellulose; O- [2-hydroxy-3-chloride;
Cationized guar gums such as (trimethylammonio) propyl guar gum; methacryloylethyldimethylbetaine / methacryloylethyltrimethylammonium chloride / methoxypolyethylene glycol methacrylate copolymer, methacryloylethyldimethylbetaine / methacryloylethyltrimethylammonium chloride / 2-hydroxyethyl methacrylate Copolymers, vinylpyrrolidone / N, N-dimethylaminoethyl methacrylic acid copolymer Methacrylic acid derivatives such as diethyl sulfate; vinylimidazolinium metochloride / vinylpyrrolidone copolymer, methylcellulose, hydroxypropylmethylcellulose, ethylcellulose, hydroxy Cellulose derivatives such as ethyl cellulose and hydroxypropyl cellulose; polyvinyl alcohol , Vinyl pyrrolidone, polyvinyl bityral, vinyl pyrrolidone / styrene copolymer, vinyl pyrrolidone / hexadecene copolymer, vinyl acetate / vinyl pyrrolidone copolymer, eicosene / vinyl pyrrolidone copolymer; vinyl acrylate; hydroxy acrylate Ethyl-methoxyethyl acrylate copolymer,
Hydroxyethyl acrylate / butyl acrylate / methoxyethyl acrylate copolymer, acrylamide / styrene copolymer, alkyl acrylate / styrene copolymer, octylamide acrylate / acrylate copolymer, alkyl acrylate Acrylic acid derivatives such as copolymers, octylamide acrylate / hydroxypropyl acrylate / butylaminoethyl methacrylate copolymer; ethylene glycol derivatives such as polyethylene glycol and highly polymerized polyethylene glycol; polyglycerin derivatives; vinyl methyl ether / maleic Maleic acid derivatives such as ethyl acrylate copolymer; propylene glycol alginate; polyamide epichlorohydrin resin; guar gum, locust bingham, quince seed, carrageenan, galactan, a Polysaccharides and derivatives thereof such as beer gum, tragacanth gum, pectin, mannan, starch, xanthan gum, dextran, curdlan, and succinoglucan; tallow derivatives such as polyoxyethylene tallow alkyl hydroxy myristylene ether; polyoxyethylene sorbitan triisostearate Sorbitan derivatives such as sugar derivatives such as polyoxypropylene methyl glucoside and polyoxyethylene dioleate methyl glucoside; acrylamide / acrylic acid / dimethyldiallylammonium chloride copolymer; acrylic acid / dimethyldiallylammonium chloride copolymer; Polymer; water-soluble collagen, hydrolyzed collagen and its derivatives (cationization, etc.), hydrolyzed keratin and its derivatives, hydrolyzed silk and its derivatives, Degraded gelatin and its derivatives, casein and its salts, hydrolyzed casein and its derivatives, hydrolyzed conchiolin and its derivatives, hydrolyzed egg white and its derivatives, soybean protein hydrolyzate and its derivatives, hydrolyzed wheat and its derivatives, hydrolyzed Elastin and its derivatives, proteins such as albumin or hydrolyzed proteins and their derivatives; succinylated carboxymethyl chitosan and the like. These polymer compounds may be used alone or in combination of two or more. The amount of these compounds is not particularly limited, but is usually used in the range of 0.01 to 10%.

The cosmetic composition of the present invention may contain a bactericide in order to impart a bactericidal action thereto. Examples of such a bactericide include benzalkonium chloride, benzethonium chloride, triclosan and trichlorocarban. , Chlorhexidine gluconate, formalin, glutaraldehyde, cresol, alkyl polyaminoethyl glycine,
Ethanol, isopropanol and the like can be mentioned, and benzalkonium chloride, benzethonium chloride, triclosan, ethanol, isopropanol and the like can be mentioned. The blending amount is not particularly limited, but is usually used in the range of 0.0001 to 10%.

Further, the cosmetic composition according to the present invention includes:
As long as the effects of the present invention are not impaired, N-long-chain acyl amino acid salts such as N-long-chain acyl acidic amino acid salts and N-long-chain acyl acidic amino acid salts;
Long-chain fatty acyl-N-methyltaurine salt, alkyl sulfate and alkylene oxide adduct thereof, fatty acid amide ether sulfate, metal salt and weak base salt of fatty acid, sulfosuccinic surfactant, alkyl phosphate and alkylene oxide adduct thereof Surfactants such as glycerin ether and its alkylene oxide adduct; ester surfactants such as glycerin ester and its alkylene oxide adduct; sorbitan esters and its alkylene Ether ester surfactants such as oxide adducts, polyoxyalkylene fatty acid esters, glycerin esters, fatty acid polyglycerin esters, sorbitan esters, sucrose fatty acid esters Nonionic surfactants such as ester-type surfactants such as stell, alkyl glucosides, hydrogenated castor oil pyroglutamic acid diester and ethylene oxide adduct thereof, and nitrogen-containing nonionic surfactants such as fatty acid alkanolamides Cationic surfactants such as aliphatic amine salts such as alkylammonium chloride and dialkylammonium chloride, quaternary ammonium salts thereof, aromatic quaternary ammonium salts such as benzalkonium salt, fatty acyl arginine esters; and carboxybetaine Various surfactants such as betaine-type surfactants, aminocarboxylic acid-type surfactants, imidazoline-type surfactants, and other amphoteric surfactants can also be added.

In order to improve product stability,
A sequestering agent (chelating agent), an antioxidant, and a preservative may be added. Amino acids such as ethylenediaminetetraacetic acid (EDTA), phosphoric acid, citric acid, L-glutamic acid diacetate, ascorbic acid,
Antioxidants such as succinic acid, gluconic acid, sodium polyphosphate and sodium metaphosphate include tocophenols, dibutylhydroxytoluene, butylhydroxyanisole, gallic esters, phosphoric acid as an antioxidant, ascorbic acid, and maleic acid Acids, malonic acid, succinic acid, fumaric acid, kephalin, hexametaphosphate, phytic acid and the like. Preservatives include paraoxybenzoates, benzoic acid, benzoates and the like. The amount of these compounds is not particularly limited, but is usually 0.0001 to
Used in the range of 10%.

The cosmetic composition of the present invention may be added with a pigment component for the purpose of coloring. Examples of such a pigment component include carbon black, mango violet, baltic violet, Red No. 201, Red No. 202, Red 204
No., Red No. 205, Red No. 220, Red No. 226, Red No. 228, Red No. 405, Orange No. 203, Orange No. 204
No. Yellow No. 205, Yellow No. 401, Blue No. 404, Red No. 3, Red No. 104, Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange 205
No. 4, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203
No. 3, Green No. 3, Blue No. 1, chlorophyll, β-carotene, and the like, and the amount can be determined arbitrarily.

The cosmetic composition of the present invention may further comprise a humectant for imparting moisturizing properties, such as pyrrolidonecarboxylic acid and its salts, hyaluronic acid and its salts, Trehalose, glycerin,
1,3-butylene glycol, propylene glycol,
Dipropylene glycol, isoprene glycol, lactate, partially hydrolyzed chitin, trimethylglycine, sorbitol; hydrolyzed proteins such as collagen and hydrolyzed silk; polyamino acid salts such as polyaspartate and polyglutamate; The amount is not particularly limited, but is usually used in the range of 0.1 to 20%.

Examples of other optional components include arbutin, kojic acid, vitamin C and derivatives thereof as whitening agents; assembly extract, cepharanthin, vitamin E and derivatives thereof, hydroquinone and derivatives thereof as vasodilators; Oryzanol; pepper tincture, ginger tincture, nicotinic acid benzyl ester as a local stimulant; vitamins A, B1, B as nutrients
2, B6, E and derivatives thereof: cystine, cysteine, acetylcysteine, methionine, serine, leucine, tryptophan, glycine, arginine, aspartic acid, glutamic acid, sodium glutamate, isoleucine, alanine, histidine, lysine, proline, oxyproline, phenylalanine , Threonine, tyrosine, valine, ε-aminocaproic acid, etc. amino acids and derivatives thereof;
Ethinyl estradiol; pantothenic acid and its derivatives as hair root activators, placenta extract, allantoin, photosensitizer 301, etc .; β-glycyrrhetinic acid, glycyrrhizic acid derivatives as anti-inflammatory agents, allantoin, azulene, ε-aminocaproic acid, hydrocortisone, hinokitiol, etc .; Tranexamic acid as an antiplasmin agent; zinc oxide, zinc sulfate, allantoin hydroxyaluminum, aluminum chloride, aluminum sulfate, sulfonate zinc carbonate, tannic acid, citric acid, lactic acid, etc. as astringents; hamamelis, odoriko grass, birch as natural products Menthol, camphor, estradiol and its ester derivatives as hormones; estrone, ethinylestradiol, cortisone and its ester Derivatives: hydrocortisone and its ester derivatives, prednisone, prednisolone, etc .; diphenhydramine hydrochloride, chlorferamine maleate as antihistamines; sulfur, salicylic acid, resorcinol as exfoliating and dissolving agents; chamomile extract and eucalyptus oil extract as natural products; For promoting metabolism, promoting blood circulation, healing wounds, etc., carrot extract, aloe, sicon, lily, loofah, horse chestnut, oak,
Benihana, etc .; as ultraviolet absorbers, benzophenone phenone derivatives, paraaminobenzoic acid derivatives, methoxycinnamic acid derivatives, salicylic acid derivatives, urocanic acid and its derivatives, 4-tert-butyl-4'-methoxydibenzoylmethane, 2- (2 '-Hydroxy-5'-methylphenyl) benzotriazole, methyl anthranilate; natural products derived from malonie, β-carotene, etc .; blood-sucking insects (mosquitoes, lice,
Dimethyl phthalate, 2-ethyl-1,3-hexanediol, bisbutylenetetrahydrofurfural, N, N-diethyl-m
-Toluamide and the like; preservatives include paraben derivatives, benzoic acid derivatives, salicylic acid derivatives and the like.

In order to prepare the cosmetic composition of the present invention by blending the various components described above, a special composition is used except that component A and / or component B and component C are used as essential components. There is no limitation, and a conventionally known ordinary method can be used.

The amount of component A and / or component B in the cosmetic composition of the present invention is appropriately determined depending on the intended product, and is not particularly limited.
The content is 1 to 50% by weight, particularly preferably 0.1 to 20% by weight. If the amount is less than 0.01% by weight, the effects of the present invention may not be sufficiently exhibited.

The amount of component C in the cosmetic composition of the present invention is appropriately determined depending on the intended product and is not particularly limited, but is usually used in the range of 0.01 to 50% by weight.

However, the ratio of component A and / or component B to component C is usually (component A and / or component B) / (component C) = 100 / 0.1 or more, preferably 100 / 0.1 1 or more. If the ratio is less than 100 / 0.1, the effects of the present invention may not be sufficiently exhibited.

The cosmetic composition of the present invention has no particular restriction on its dosage form, and may be emulsified, solution-based, solubilized, gel-like,
Any dosage form, such as a powder dispersion system, a water-oil two-layer system, a water-oil-powder three-layer system, may be used.

The use of the cosmetic composition of the present invention is not particularly limited, and the shampoo, rinse, rinse-in shampoo, conditioning shampoo, hair lotion, hair conditioner, hair treatment, hair cream, hair spray, hair liquid, Hair wax, hair water, hair styling gel, hair styling agent, perm solution, hair color, acidic hair color, hair manicure, lotion, emulsion, facial cleanser, mouthwash, makeup remover, cleansing lotion, emollient lotion, nourishing cream , Emollient cream, massage cream, cleansing cream, body shampoo, hand soap, shave cream, tanning cosmetics, deodorant powder, deodorant lotion, deo Widely used as various cosmetics such as runt spray, makeup remover gel, moisturizing gel, moisturizing essence, UV protection essence, shaving foam, white powder, foundation, lipstick, blusher, eyeliner, eye shadow, eyebrow ink, mascara, bath salt, etc. Can be.

[0058]

The present invention will be further described below with reference to comparative examples and examples.

Comparative Examples 1 to 4 and Examples 1 to 5 (Rinse) Compositions shown in Table 1 below (indicated by pure weight%, total amount 100)
%) Was prepared by a conventional method, and ten professional panelists washed the hair with a commercially available shampoo and then used these rinses. (A) Sticky feeling at the time of application, (b) Sticky feeling after drying, (c) Sensory evaluation was performed on the goodness of combing and (d) the smoothness of the hair. The results are also shown in the table.

Here, in the sensory evaluation, an average value was calculated according to the following evaluation criteria, and the case where the average value was 1.5 to 2.0 was very good (◎), and the average value was 1.0 to less than 1.5. Was evaluated as good (○), the case of 0.5 to less than 1.0 as normal (△), and the case of −1 to less than 0.5 as poor (×).

<Evaluation Criteria> (a) Stickiness at the time of coating 2: No stickiness 1: Not very sticky 0: Slightly sticky -1: Sticky

(B) Sticky feeling after drying 2: No sticky feeling 1: Not so sticky 0: Slightly sticky -1: There is sticky feeling

(C) Good combability 2: Good combability 1: Good combability 0: Normal -1: Bad combability

(D) Smoothness 2: Smooth 1: Slightly smooth 0: Normal -1: Not smooth

[0065]

[Table 1]

Comparative Examples 5 to 7 and Examples 6 to 8 (Emulsion)
%) Was prepared by a conventional method, and ten expert panelists used these emulsions, and were used for (a) sticky feeling, (b) smoothness, (c) good spreadability, and (d) good fit. An evaluation was performed. The results are also shown in the table.

Here, the sensory evaluation was performed by calculating an average value according to the following evaluation criteria. When the average value was 1.5 to 2.0, the average was very good (（), and the average value was 1.0 to less than 1.5. Was evaluated as good (○), the case of 0.5 to less than 1.0 as normal (△), and the case of −1 to less than 0.5 as poor (×).

<Evaluation Criteria> (a) Stickiness at the time of application 2: No stickiness 1: Not very sticky 0: Slight stickiness -1: Stickiness

(B) Smoothness 2: Very good 1: Good 0: Normal -1: Poor

(C) Good spread 2: Very good 1: Good 0: Normal -1: Bad

(D) Familiarity 2: Very good 1: Good 0: Normal -1: Poor

[0072]

[Table 2]

Examples 9 to 17 (Shampoo) Table 3 below lists nine examples of shampoo formulations.

[0074]

[Table 3]

Examples 18 to 30 (rinse) Table 4 below lists 13 examples of rinsing formulations.

[0076]

[Table 4]

Examples 31 to 39 (Rinse) Table 5 below lists nine examples of rinse formulations.

[0078]

[Table 5]

Examples 40 to 47 (rinse) In Table 6 below, eight examples of rinsing are listed.

[0080]

[Table 6]

Examples 48 to 51 (rinse) Table 7 below shows four examples of rinsing formulations.

[0082]

[Table 7]

Examples 52 to 59 (Treatment) Table 8 below shows eight examples of treatment formulations.

[0084]

[Table 8]

Examples 60 to 65 (Treatment) Table 9 below shows six examples of treatment formulations.

[0086]

[Table 9]

Examples 66 to 71 (hair cream) Table 10 below shows six examples of hair cream formulations.

[0088]

[Table 10]

Examples 72 to 79 (Hair Cream) Table 11 below shows eight examples of hair cream formulations.

[0090]

[Table 11]

Examples 80 to 86 (Emulsion) Table 12 below shows seven examples of the formulation of the emulsion.

[0092]

[Table 12]

Examples 87 to 90 (Emulsion) Table 13 below shows four examples of the formulation of the emulsion.

[0094]

[Table 13]

Examples 91 to 94 (Emulsion) Table 14 below shows four examples of the formulation of the emulsion.

[0096]

[Table 14]

Examples 95 to 98 (Cleansing Cream) In Table 15 below, four examples of cleansing cream formulations are listed.

[0098]

[Table 15]

Examples 99 to 102 (lipsticks) Table 16 below shows four examples of lipstick formulations.

[0100]

[Table 16]

Examples 103 to 104 (shaving lotion) Table 17 below shows two examples of formulations of shaving lotions.

[0102]

[Table 17]

Example 105 (1 permanent agent) Table 18 below shows one formulation example of one permanent agent.

[0104]

[Table 18]

Examples 106 to 110 (bath agents) Table 19 below lists five examples of bath agent formulations.

[0106]

[Table 19]

Example 111 (pack) Table 20 below shows an example of the composition of the pack.

[0108]

[Table 20]

Examples 112 to 117 (W / O skin cream) Table 21 below shows six examples of W / O skin cream formulations.

[0110]

[Table 21]

Examples 118 to 129 (pressed powder type foundation) Table 22 below lists 12 examples of the composition of the pressed powder type foundation.

[0112]

[Table 22]

Examples 130 to 141 (pressed powder) Table 23 below lists 12 examples of the blended pressed powder.

[0114]

[Table 23]

Examples 142 to 153 (pressed powder type foundation) Table 24 below lists 12 examples of the composition of the pressed powder type foundation.

[0116]

[Table 24]

Examples 154 to 158 (Mascara) Table 25 below shows five examples of mascara formulations.

[0118]

[Table 25]

Examples 159 to 167 (Eyeliner) Table 26 below lists nine examples of eyeliner formulations.

[0120]

[Table 26]

Examples 168 to 173 (Emulsified Foundation) Table 27 below shows six examples of emulsified foundations.

[0122]

[Table 27]

Examples 174 to 182 (Eye Shadow) Table 28 below lists nine examples of eye shadow formulations.

[0124]

[Table 28]

Examples 183 to 188 (smoke red) Table 29 below shows six examples of mixes of magenta.

[0126]

[Table 29]

Examples 189 to 200 (lipstick) Table 30 below lists 12 examples of lipstick formulations.

[0128]

[Table 30]

Examples 201 to 209 (Oil-based foundation) Table 31 below lists nine examples of oil-based foundation formulations.

[0130]

[Table 31]

Examples 210 to 221 (Powder paste) Table 32 below lists 12 examples of powder paste compositions.

[0132]

[Table 32]

[0133]

According to the present invention, the sticky feeling peculiar to oil-based raw materials is improved, and the feeling of use such as spread, conformity and smoothness to the skin, smoothness and softness to the hair, good combability, etc. Can easily provide a cosmetic having an excellent conditioning effect.

────────────────────────────────────────────────── ───

[Procedure amendment]

[Submission date] June 1, 1999 (1999.6.1)

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] Claim 2

[Correction method] Change

[Correction contents]

Embedded image(Where R¹Is a straight or branched chain having 5 to 21 carbon atoms
An alkyl or alkenyl group is represented by R²Is a hydrogen atom or charcoal
A linear or branched alkyl group having 1 to 3 atoms is represented by R³
Is a hydrogen atom or a straight or branched chain having 1 to 4 carbon atoms.
Alkyl group to R ⁴Is a branched or straight chain having 1 to 10 carbon atoms
A chain alkyl or alkenyl group and m is from 0 to 2
Indicates an integer. )

[Procedure amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0015

[Correction method] Change

[Correction contents]

[0015]

Embedded image

Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat II (reference) A61K 7/035 A61K 7/035 7/06 7/06 7/075 7/075 7/08 7/08 7/09 7 / 09 7/15 7/15 7/48 7/48 7/50 7/50

Claims (6)

[Claims] 1. An ester of an N-long-chain acyl-neutral amino acid having a straight-chain or branched-chain saturated or unsaturated acyl group having 6 to 22 carbon atoms, the hydrocarbon group constituting the alcohol moiety thereof Is a linear or branched saturated or unsaturated hydrocarbon group having 1 to 10 carbon atoms, an N-long-chain acyl neutral amino acid ester (component A) or / and a straight chain having 6 to 22 carbon atoms. Or a diester of an N-long-chain acyl acidic amino acid having a saturated or unsaturated branched-chain acyl group, wherein the hydrocarbon group constituting the alcohol site is a saturated or linear saturated or branched chain having 1 to 10 carbon atoms. A cosmetic composition comprising, as active ingredients, a diester of an N-long-chain acyl acidic amino acid (component B) and an oily raw material for cosmetics (component C), which are unsaturated hydrocarbon groups. 2. The method according to claim 1, wherein the N-long-chain acyl neutral amino acid ester is
Characterized by being represented by the general formula (1)
The cosmetic composition according to claim 1. Embedded image(Where R¹Is a straight or branched chain having 5 to 21 carbon atoms
An alkyl or alkenyl group is represented by R²Is a hydrogen atom or charcoal
A linear or branched alkyl group having 1 to 3 atoms is represented by R³
Is a hydrogen atom or a straight or branched chain having 1 to 4 carbon atoms.
Alkyl group to R ⁴Is a branched or straight chain having 1 to 10 carbon atoms
A chain alkyl or alkenyl group and m is from 0 to 2
Indicates an integer. ) 3. The cosmetic composition according to claim 1, wherein the N-long-chain acyl acidic amino acid diester is represented by the following general formula (2). Embedded image (In the formula, R ⁵ represents a branched or straight-chain alkyl or alkenyl group having ^{5 to} 21 carbon atoms, and R ⁶ and R ⁷ each independently represent a straight-chain or branched alkyl having 1 to 10 carbon atoms. And n represents an integer of 0 or 1.) 4. The neutral amino acid constituting the N-long-chain acyl neutral amino acid ester is a neutral amino acid selected from sarcosine, alanine, glycine and N-methyl-β-alanine. The cosmetic composition according to any one of claims 1 to 3, wherein 5. The cosmetic composition according to claim 1, wherein the alcohol moiety of the N-long-chain acyl neutral amino acid ester is an isopropyl group. 6. The N-long-chain acyl neutral amino acid ester wherein the acyl group is a lauroyl group.
The cosmetic composition according to any one of claims 1 to 5, wherein