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ITRM950303A0 - Nuovi seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono. - Google Patents

Nuovi seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono.

Info

Publication number
ITRM950303A0
ITRM950303A0 ITRM950303A ITRM950303A ITRM950303A0 IT RM950303 A0 ITRM950303 A0 IT RM950303A0 IT RM950303 A ITRM950303 A IT RM950303A IT RM950303 A ITRM950303 A IT RM950303A IT RM950303 A0 ITRM950303 A0 IT RM950303A0
Authority
IT
Italy
Prior art keywords
steroids
contain
processes
preparation
pharmaceutical compositions
Prior art date
Application number
ITRM950303A
Other languages
English (en)
Inventor
Mauro Gobbini
Patrizia Ferrari
Piero Melloni
Marco Torri
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM950303A0 publication Critical patent/ITRM950303A0/it
Priority to IT95RM000303A priority Critical patent/IT1282286B1/it
Priority to AT96830206T priority patent/ATE181324T1/de
Priority to DE69602886T priority patent/DE69602886T2/de
Priority to EP96830206A priority patent/EP0742214B1/en
Priority to ES96830206T priority patent/ES2133918T3/es
Priority to DK96830206T priority patent/DK0742214T3/da
Priority to US08/632,124 priority patent/US5731345A/en
Priority to CA002174715A priority patent/CA2174715A1/en
Priority to JP8106864A priority patent/JPH09291086A/ja
Publication of ITRM950303A1 publication Critical patent/ITRM950303A1/it
Application granted granted Critical
Publication of IT1282286B1 publication Critical patent/IT1282286B1/it
Priority to GR990402200T priority patent/GR3031118T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
IT95RM000303A 1995-05-11 1995-05-11 Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono. IT1282286B1 (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT95RM000303A IT1282286B1 (it) 1995-05-11 1995-05-11 Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono.
ES96830206T ES2133918T3 (es) 1995-05-11 1996-04-11 Nuevos esteroides seco-d activos en el sistema cardiovascular y composiciones farmaceuticas que los contienen.
DE69602886T DE69602886T2 (de) 1995-05-11 1996-04-11 Im kardiovaskulären System aktive seco-D-Steroide und diese enthaltende pharmazeutische Zubereitungen
EP96830206A EP0742214B1 (en) 1995-05-11 1996-04-11 Seco-D steroids active in the cardiovascular system and pharmaceutical compositions containing same
AT96830206T ATE181324T1 (de) 1995-05-11 1996-04-11 Im kardiovaskulären system aktive seco-d-steroide und diese enthaltende pharmazeutische zubereitungen
DK96830206T DK0742214T3 (da) 1995-05-11 1996-04-11 I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne
US08/632,124 US5731345A (en) 1995-05-11 1996-04-15 Seco-D steroids active on the cardiovascular system and pharmaceutical compositions containing same
CA002174715A CA2174715A1 (en) 1995-05-11 1996-04-22 Seco-d steroids active on the cardiovascular system and pharmaceutical compositions containing same
JP8106864A JPH09291086A (ja) 1995-05-11 1996-04-26 心血管系に活性な新規ｓｅｃｏ−Ｄステロイド類および同ステロイドを含有する医薬組成物
GR990402200T GR3031118T3 (en) 1995-05-11 1999-08-31 Novel seco-D steroids active in the cardiovascular system and pharmaceutical compositions containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95RM000303A IT1282286B1 (it) 1995-05-11 1995-05-11 Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono.

Publications (3)

Publication Number Publication Date
ITRM950303A0 true ITRM950303A0 (it) 1995-05-11
ITRM950303A1 ITRM950303A1 (it) 1996-11-11
IT1282286B1 IT1282286B1 (it) 1998-03-16

Family

ID=11403363

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95RM000303A IT1282286B1 (it) 1995-05-11 1995-05-11 Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono.

Country Status (10)

Country Link
US (1) US5731345A (it)
EP (1) EP0742214B1 (it)
JP (1) JPH09291086A (it)
AT (1) ATE181324T1 (it)
CA (1) CA2174715A1 (it)
DE (1) DE69602886T2 (it)
DK (1) DK0742214T3 (it)
ES (1) ES2133918T3 (it)
GR (1) GR3031118T3 (it)
IT (1) IT1282286B1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19633376A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue Seco-D-Steroide, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20040064050A1 (en) * 2002-09-20 2004-04-01 Jun Liu System and method for screening tissue
JP2008539047A (ja) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド ファーマインフォーマティックスシステム
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
WO2007060206A2 (en) * 2005-11-25 2007-05-31 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Further crystalline forms of rostafuroxin
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4221636C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate
DE4221538C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti 14-Desoxy-14alpha-cardenolid-3beta-thioderivate
DE4227605C2 (de) * 1992-08-20 1995-02-16 Sigma Tau Ind Farmaceuti 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten

Also Published As

Publication number Publication date
DK0742214T3 (da) 1999-12-13
ES2133918T3 (es) 1999-09-16
IT1282286B1 (it) 1998-03-16
DE69602886T2 (de) 1999-11-04
GR3031118T3 (en) 1999-12-31
ITRM950303A1 (it) 1996-11-11
DE69602886D1 (de) 1999-07-22
EP0742214B1 (en) 1999-06-16
EP0742214A1 (en) 1996-11-13
US5731345A (en) 1998-03-24
ATE181324T1 (de) 1999-07-15
CA2174715A1 (en) 1996-11-12
JPH09291086A (ja) 1997-11-11

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Legal Events

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