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ITPD930045A1 - Derivati o-solfatati di gangliosidi e lisogangliosidi - Google Patents

Derivati o-solfatati di gangliosidi e lisogangliosidi

Info

Publication number
ITPD930045A1
ITPD930045A1 IT93PD000045A ITPD930045A ITPD930045A1 IT PD930045 A1 ITPD930045 A1 IT PD930045A1 IT 93PD000045 A IT93PD000045 A IT 93PD000045A IT PD930045 A ITPD930045 A IT PD930045A IT PD930045 A1 ITPD930045 A1 IT PD930045A1
Authority
IT
Italy
Prior art keywords
lysogangliosides
gangliosides
sulphated derivatives
sulphated
derivatives
Prior art date
Application number
IT93PD000045A
Other languages
English (en)
Inventor
Aurelio Romeo
Gunter Kirschner
Carlo Chizzolini
Hari Manev
Laura Facci
Original Assignee
Fidia S P A In Amministrazione
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia S P A In Amministrazione filed Critical Fidia S P A In Amministrazione
Publication of ITPD930045A0 publication Critical patent/ITPD930045A0/it
Priority to IT93PD000045A priority Critical patent/IT1267956B1/it
Priority to AU63521/94A priority patent/AU694105B2/en
Priority to ES94910741T priority patent/ES2159554T3/es
Priority to PCT/US1994/001965 priority patent/WO1994020515A1/en
Priority to US08/530,275 priority patent/US5849717A/en
Priority to AT94910741T priority patent/ATE204287T1/de
Priority to JP6520041A priority patent/JPH08507307A/ja
Priority to CA002157359A priority patent/CA2157359A1/en
Priority to KR1019950703684A priority patent/KR960701073A/ko
Priority to DE69427966T priority patent/DE69427966T2/de
Priority to EP94910741A priority patent/EP0688330B1/en
Publication of ITPD930045A1 publication Critical patent/ITPD930045A1/it
Application granted granted Critical
Publication of IT1267956B1 publication Critical patent/IT1267956B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invenzione ha per oggetto dei nuovi derivati 0-solfatati di gangliosidi e lisogangliosidi e più precisamente N-ed N'-acil-lisogangliosidi, in cui N ed N', indicano rispettivamente il gruppo aminico della sfingosina e dell'acido neuroaminico.
IT93PD000045A 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi IT1267956B1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT93PD000045A IT1267956B1 (it) 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi
JP6520041A JPH08507307A (ja) 1993-03-04 1994-03-04 新規ｏ−硫酸化ガングリオシドおよびリゾ−ガングリオシド誘導体
ES94910741T ES2159554T3 (es) 1993-03-04 1994-03-04 Nuevos derivados gangliosidos y liso-gangliosidos o-sulfatados.
PCT/US1994/001965 WO1994020515A1 (en) 1993-03-04 1994-03-04 New o-sulfated gangliosides and lyso-ganglioside derivatives
US08/530,275 US5849717A (en) 1993-03-04 1994-03-04 O-sulfated gangliosides and lyso-ganglioside derivatives
AT94910741T ATE204287T1 (de) 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten
AU63521/94A AU694105B2 (en) 1993-03-04 1994-03-04 New O-sulfated gangliosides and lyso-ganglioside derivatives
CA002157359A CA2157359A1 (en) 1993-03-04 1994-03-04 New o-sulfated gangliosides and lyso-ganglioside derivatives
KR1019950703684A KR960701073A (ko) 1993-03-04 1994-03-04 신규 o-황산염화 강글리오시드 및 리소-강글리오시드 유도체(new o-sulfated gangliosides and lyso-ganglioside derivatives)
DE69427966T DE69427966T2 (de) 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso-ganglioside-derivaten
EP94910741A EP0688330B1 (en) 1993-03-04 1994-03-04 New o-sulfated gangliosides and lyso-ganglioside derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93PD000045A IT1267956B1 (it) 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi

Publications (3)

Publication Number Publication Date
ITPD930045A0 ITPD930045A0 (it) 1993-03-04
ITPD930045A1 true ITPD930045A1 (it) 1994-09-04
IT1267956B1 IT1267956B1 (it) 1997-02-18

Family

ID=11390210

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93PD000045A IT1267956B1 (it) 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi

Country Status (10)

Country Link
EP (1) EP0688330B1 (it)
JP (1) JPH08507307A (it)
KR (1) KR960701073A (it)
AT (1) ATE204287T1 (it)
AU (1) AU694105B2 (it)
CA (1) CA2157359A1 (it)
DE (1) DE69427966T2 (it)
ES (1) ES2159554T3 (it)
IT (1) IT1267956B1 (it)
WO (1) WO1994020515A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1267955B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati solfatati dei lisogangliosidi
JP5663576B2 (ja) 2010-07-06 2015-02-04 秀則 上西 神経突起伸長剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
JPH03246297A (ja) * 1990-02-22 1991-11-01 Nippon Koutai Kenkyusho:Kk ガングリオシド誘導体及びこれを含有する抗ｈｉｖ剤
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
JPH08507307A (ja) 1996-08-06
WO1994020515A1 (en) 1994-09-15
EP0688330A1 (en) 1995-12-27
CA2157359A1 (en) 1994-09-15
AU694105B2 (en) 1998-07-16
DE69427966T2 (de) 2002-04-04
ATE204287T1 (de) 2001-09-15
ES2159554T3 (es) 2001-10-16
AU6352194A (en) 1994-09-26
EP0688330B1 (en) 2001-08-16
IT1267956B1 (it) 1997-02-18
DE69427966D1 (de) 2001-09-20
ITPD930045A0 (it) 1993-03-04
KR960701073A (ko) 1996-02-24

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Effective date: 19990210