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ITMI20020773A1 - Farmaci per il trattamento dell'artrite - Google Patents

Farmaci per il trattamento dell'artrite

Info

Publication number
ITMI20020773A1
ITMI20020773A1 IT2002MI000773A ITMI20020773A ITMI20020773A1 IT MI20020773 A1 ITMI20020773 A1 IT MI20020773A1 IT 2002MI000773 A IT2002MI000773 A IT 2002MI000773A IT MI20020773 A ITMI20020773 A IT MI20020773A IT MI20020773 A1 ITMI20020773 A1 IT MI20020773A1
Authority
IT
Italy
Prior art keywords
arthritis
drugs
treatment
Prior art date
Application number
IT2002MI000773A
Other languages
English (en)
Inventor
Soldato Piero Del
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Priority to IT2002MI000773A priority Critical patent/ITMI20020773A1/it
Publication of ITMI20020773A0 publication Critical patent/ITMI20020773A0/it
Priority to EP03720377A priority patent/EP1492543A1/en
Priority to JP2003581790A priority patent/JP2005522472A/ja
Priority to PCT/EP2003/003183 priority patent/WO2003084550A1/en
Priority to AU2003224002A priority patent/AU2003224002A1/en
Priority to US10/509,675 priority patent/US20070010458A1/en
Publication of ITMI20020773A1 publication Critical patent/ITMI20020773A1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT2002MI000773A 2002-04-11 2002-04-11 Farmaci per il trattamento dell'artrite ITMI20020773A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT2002MI000773A ITMI20020773A1 (it) 2002-04-11 2002-04-11 Farmaci per il trattamento dell'artrite
EP03720377A EP1492543A1 (en) 2002-04-11 2003-03-27 Drugs for the arthritis treatment
JP2003581790A JP2005522472A (ja) 2002-04-11 2003-03-27 関節炎の治療用薬剤
PCT/EP2003/003183 WO2003084550A1 (en) 2002-04-11 2003-03-27 Drugs for the arthritis treatment
AU2003224002A AU2003224002A1 (en) 2002-04-11 2003-03-27 Drugs for the arthritis treatment
US10/509,675 US20070010458A1 (en) 2002-04-11 2003-03-27 Drugs for the arthritis treatment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI000773A ITMI20020773A1 (it) 2002-04-11 2002-04-11 Farmaci per il trattamento dell'artrite

Publications (2)

Publication Number Publication Date
ITMI20020773A0 ITMI20020773A0 (it) 2002-04-11
ITMI20020773A1 true ITMI20020773A1 (it) 2003-10-13

Family

ID=11449687

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002MI000773A ITMI20020773A1 (it) 2002-04-11 2002-04-11 Farmaci per il trattamento dell'artrite

Country Status (6)

Country Link
US (1) US20070010458A1 (it)
EP (1) EP1492543A1 (it)
JP (1) JP2005522472A (it)
AU (1) AU2003224002A1 (it)
IT (1) ITMI20020773A1 (it)
WO (1) WO2003084550A1 (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100486573C (zh) 1999-12-23 2009-05-13 硝化医药股份有限公司 硝基化的和亚硝基化的环加氧酶-2抑制剂、组合物及其用途
CA2487414A1 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2004004648A2 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US8173840B2 (en) 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
US7589233B2 (en) 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
US7585997B2 (en) 2003-12-31 2009-09-08 Chesterford Enterprises Limited Compounds and compositions for treating dysproliferative diseases, and methods of use thereof
JP2007520483A (ja) 2004-01-27 2007-07-26 メルク フロスト カンパニー シクロオキシゲナーゼ−2インヒビターとしてのジアリール−2−(5h)−フラノンの一酸化窒素放出プロドラッグ
JP2007520484A (ja) 2004-01-27 2007-07-26 メルク フロスト カンパニー シクロオキシゲナーゼ−2インヒビターとしてのジアリール−2−(5h)−フラノンの一酸化窒素放出プロドラッグ
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
JP5198063B2 (ja) 2004-08-26 2013-05-15 アッパラオ・サティアム 新規バイオ開裂性リンカー
US7586003B2 (en) * 2005-07-14 2009-09-08 Zinpro Corporation Derivatives of seleno-amino acids
AU2008286954B2 (en) 2007-08-10 2015-01-15 Basil Rigas Anti-inflammatory compounds and uses thereof
EP2188245B1 (en) 2007-08-17 2013-11-06 Council of Scientific & Industrial Research Nitric oxide releasing derivatives of paracetamol
US9844599B2 (en) 2013-01-21 2017-12-19 Apparao Satyam Nitric oxide releasing produgs of therapeutic agents
CN108864008B (zh) * 2017-05-09 2021-10-22 江苏康缘药业股份有限公司 一种橙酮类化合物及其制备方法与应用
CN111116529A (zh) * 2020-01-13 2020-05-08 江苏康缘药业股份有限公司 一种具有抗炎作用的化合物及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2998450A (en) * 1958-05-19 1961-08-29 Warner Lambert Pharmaceutical Process of preparing nu-acetyl-p-amino phenol
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
US3600437A (en) * 1969-05-28 1971-08-17 Lilly Co Eli Substituted phenylalkanoic acids and derivatives thereof
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US3784701A (en) * 1970-09-21 1974-01-08 American Cyanamid Co Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain
US3843681A (en) * 1971-06-01 1974-10-22 American Home Prod 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives
US4035376A (en) * 1972-10-24 1977-07-12 Janssen Pharmaceutica N.V. Aroyl-substituted phenylacetic acid derivatives
US3997669A (en) * 1972-12-26 1976-12-14 Ciba-Geigy Corporation Tertiary aminoacids
US4061779A (en) * 1973-09-11 1977-12-06 Beecham Group Limited Naphthalene derivatives having anti-inflammatory activity
US4161538A (en) * 1977-04-05 1979-07-17 Sankyo Company Limited Substituted phenylacetic acid derivatives and process for the preparation thereof
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
EP0759899B1 (en) * 1994-05-10 1999-09-15 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
DE4420523A1 (de) * 1994-06-13 1995-12-14 Cassella Ag Verwendung von NO-freisetzenden Verbindungen zur Behandlung und Vorbeugung von systemischen Entzündungssyndromen
WO2002026748A2 (en) * 2000-09-25 2002-04-04 The Procter & Gamble Company Metal complexes for use in medical and therapeutic applications
AU2002242138A1 (en) * 2001-02-16 2002-10-03 Lavipharm Laboratories Inc. Water soluble and palatable complexes

Also Published As

Publication number Publication date
AU2003224002A1 (en) 2003-10-20
JP2005522472A (ja) 2005-07-28
US20070010458A1 (en) 2007-01-11
EP1492543A1 (en) 2005-01-05
ITMI20020773A0 (it) 2002-04-11
WO2003084550A1 (en) 2003-10-16

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