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ITMI931264A1 - Processo per la sintesi della 9-(2-idrossietossimetil)- guanina - Google Patents

Processo per la sintesi della 9-(2-idrossietossimetil)- guanina

Info

Publication number
ITMI931264A1
ITMI931264A1 IT001264A ITMI931264A ITMI931264A1 IT MI931264 A1 ITMI931264 A1 IT MI931264A1 IT 001264 A IT001264 A IT 001264A IT MI931264 A ITMI931264 A IT MI931264A IT MI931264 A1 ITMI931264 A1 IT MI931264A1
Authority
IT
Italy
Prior art keywords
synthesis
idrossietossimetil
guanina
guanine
acyclovir
Prior art date
Application number
IT001264A
Other languages
English (en)
Inventor
Tiberio Bruzzese
Giuseppe Guazzi
Giuliano Marconi
Marco Rognoni
Original Assignee
Solar Chem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solar Chem Sa filed Critical Solar Chem Sa
Priority to IT93MI001264A priority Critical patent/IT1264599B1/it
Publication of ITMI931264A0 publication Critical patent/ITMI931264A0/it
Priority to DE69409578T priority patent/DE69409578T2/de
Priority to ES94108426T priority patent/ES2117172T3/es
Priority to DK94108426T priority patent/DK0628558T3/da
Priority to EP94108426A priority patent/EP0628558B1/en
Priority to AT94108426T priority patent/ATE165096T1/de
Priority to US08/261,053 priority patent/US5496945A/en
Publication of ITMI931264A1 publication Critical patent/ITMI931264A1/it
Application granted granted Critical
Publication of IT1264599B1 publication Critical patent/IT1264599B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT93MI001264A 1993-06-14 1993-06-14 Processo per la sintesi della 9-(2-idrossietossimetil)- guanina IT1264599B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT93MI001264A IT1264599B1 (it) 1993-06-14 1993-06-14 Processo per la sintesi della 9-(2-idrossietossimetil)- guanina
DE69409578T DE69409578T2 (de) 1993-06-14 1994-06-01 Verfahren für die Synthese von 9-(2-Hydroxyethoxymethyl)guanin
ES94108426T ES2117172T3 (es) 1993-06-14 1994-06-01 Procedimiento de sintesis de la 9-(2-hidroxi etoxi metil)guanina.
DK94108426T DK0628558T3 (da) 1993-06-14 1994-06-01 Fremgangsmåde til syntese af 9-(2-hydroxyethoxymethyl)-guanin
EP94108426A EP0628558B1 (en) 1993-06-14 1994-06-01 Process for the synthesis of 9(2-hydroxyethoxy methyl) guanine
AT94108426T ATE165096T1 (de) 1993-06-14 1994-06-01 Verfahren für die synthese von 9-(2- hydroxyethoxymethyl)guanin
US08/261,053 US5496945A (en) 1993-06-14 1994-06-13 Process for the synthesis of 9-(2-hydroxyethoxy methyl) guanine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001264A IT1264599B1 (it) 1993-06-14 1993-06-14 Processo per la sintesi della 9-(2-idrossietossimetil)- guanina

Publications (3)

Publication Number Publication Date
ITMI931264A0 ITMI931264A0 (it) 1993-06-14
ITMI931264A1 true ITMI931264A1 (it) 1994-12-14
IT1264599B1 IT1264599B1 (it) 1996-10-04

Family

ID=11366388

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001264A IT1264599B1 (it) 1993-06-14 1993-06-14 Processo per la sintesi della 9-(2-idrossietossimetil)- guanina

Country Status (7)

Country Link
US (1) US5496945A (it)
EP (1) EP0628558B1 (it)
AT (1) ATE165096T1 (it)
DE (1) DE69409578T2 (it)
DK (1) DK0628558T3 (it)
ES (1) ES2117172T3 (it)
IT (1) IT1264599B1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276126B1 (it) * 1995-11-14 1997-10-27 Archimica Spa Procedimento per la preparazine di 9-((2-idrossietossi)metil) guanina
CN103601768B (zh) * 2013-11-13 2015-09-30 齐鲁天和惠世制药有限公司 一种阿米卡星的制备方法
CN107903268A (zh) * 2017-11-16 2018-04-13 湖北省宏源药业科技股份有限公司 一种阿昔洛韦的提纯方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
DK135489D0 (da) * 1989-03-20 1989-03-20 Gea Farmaceutisk Fabrik As Fremgangsmaade til fremstilling af 9-substituerede guaninderivater og mellemprodukter til brug ved fremgangsmaaden
JP3225545B2 (ja) * 1991-09-18 2001-11-05 味の素株式会社 非環状ヌクレオシド類の製造法

Also Published As

Publication number Publication date
DE69409578T2 (de) 1998-11-19
US5496945A (en) 1996-03-05
ES2117172T3 (es) 1998-08-01
EP0628558B1 (en) 1998-04-15
DE69409578D1 (de) 1998-05-20
ATE165096T1 (de) 1998-05-15
IT1264599B1 (it) 1996-10-04
DK0628558T3 (da) 1999-02-08
ITMI931264A0 (it) 1993-06-14
EP0628558A1 (en) 1994-12-14

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970626