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IT201900023937A1 - Procedimento per la preparazione di Lasmiditan e di un intermedio di sintesi - Google Patents

Procedimento per la preparazione di Lasmiditan e di un intermedio di sintesi

Info

Publication number
IT201900023937A1
IT201900023937A1 IT102019000023937A IT201900023937A IT201900023937A1 IT 201900023937 A1 IT201900023937 A1 IT 201900023937A1 IT 102019000023937 A IT102019000023937 A IT 102019000023937A IT 201900023937 A IT201900023937 A IT 201900023937A IT 201900023937 A1 IT201900023937 A1 IT 201900023937A1
Authority
IT
Italy
Prior art keywords
lasmiditan
preparation
synthetic intermediate
synthetic
Prior art date
Application number
IT102019000023937A
Other languages
English (en)
Inventor
Giuseppe Cremonesi
Christian Invernizzi
Mara Sada
Lazzaro Feliciani
Giorgio Bertolini
Original Assignee
Olon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olon Spa filed Critical Olon Spa
Priority to IT102019000023937A priority Critical patent/IT201900023937A1/it
Priority to US17/783,449 priority patent/US20230098051A1/en
Priority to CA3160699A priority patent/CA3160699A1/en
Priority to PCT/IB2020/061769 priority patent/WO2021116979A1/en
Priority to EP20830326.3A priority patent/EP4073056B1/en
Publication of IT201900023937A1 publication Critical patent/IT201900023937A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT102019000023937A 2019-12-13 2019-12-13 Procedimento per la preparazione di Lasmiditan e di un intermedio di sintesi IT201900023937A1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT102019000023937A IT201900023937A1 (it) 2019-12-13 2019-12-13 Procedimento per la preparazione di Lasmiditan e di un intermedio di sintesi
US17/783,449 US20230098051A1 (en) 2019-12-13 2020-12-10 Process for the preparation of lasmiditan and of a synthesis intermediate
CA3160699A CA3160699A1 (en) 2019-12-13 2020-12-10 Process for the preparation of lasmiditan and of a synthesis intermediate
PCT/IB2020/061769 WO2021116979A1 (en) 2019-12-13 2020-12-10 Process for the preparation of lasmiditan and of a synthesis intermediate
EP20830326.3A EP4073056B1 (en) 2019-12-13 2020-12-10 Process for the preparation of lasmiditan and of a synthesis intermediate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000023937A IT201900023937A1 (it) 2019-12-13 2019-12-13 Procedimento per la preparazione di Lasmiditan e di un intermedio di sintesi

Publications (1)

Publication Number Publication Date
IT201900023937A1 true IT201900023937A1 (it) 2021-06-13

Family

ID=70155033

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102019000023937A IT201900023937A1 (it) 2019-12-13 2019-12-13 Procedimento per la preparazione di Lasmiditan e di un intermedio di sintesi

Country Status (5)

Country Link
US (1) US20230098051A1 (it)
EP (1) EP4073056B1 (it)
CA (1) CA3160699A1 (it)
IT (1) IT201900023937A1 (it)
WO (1) WO2021116979A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202100023861A1 (it) * 2021-09-16 2023-03-16 Procos Spa Processo per la preparazione di (6-alopiridin-2-il)(1-metilpiperidin-4-il)metanone
CN115947718A (zh) * 2021-10-10 2023-04-11 山东新时代药业有限公司 一种拉司米地坦中间体的制备方法
CN113866318B (zh) * 2021-10-21 2023-07-04 佛山奕安赛医药科技有限公司 一种(6-氨基吡啶-2-基)(1-甲基哌啶-4-基)甲酮双盐酸盐的检测方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084949A1 (en) 2002-03-29 2003-10-16 Eli Lilly And Company Pyridinoylpiperidines as 5-ht1f agonists
WO2011123654A1 (en) 2010-04-02 2011-10-06 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084949A1 (en) 2002-03-29 2003-10-16 Eli Lilly And Company Pyridinoylpiperidines as 5-ht1f agonists
WO2011123654A1 (en) 2010-04-02 2011-10-06 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MOHAMMED K. ELMKADDEM ET AL: "Efficient synthesis of aminopyridine derivatives by copper catalyzed amination reactions", CHEMICAL COMMUNICATIONS, vol. 46, no. 6, 1 December 2009 (2009-12-01), pages 925 - 927, XP055713355, ISSN: 1359-7345, DOI: 10.1039/B916569J *

Also Published As

Publication number Publication date
EP4073056B1 (en) 2024-04-17
WO2021116979A1 (en) 2021-06-17
CA3160699A1 (en) 2021-06-17
US20230098051A1 (en) 2023-03-30
EP4073056C0 (en) 2024-04-17
EP4073056A1 (en) 2022-10-19

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