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IT201900022029A1 - Formulazioni oftalmiche - Google Patents

Formulazioni oftalmiche

Info

Publication number
IT201900022029A1
IT201900022029A1 IT102019000022029A IT201900022029A IT201900022029A1 IT 201900022029 A1 IT201900022029 A1 IT 201900022029A1 IT 102019000022029 A IT102019000022029 A IT 102019000022029A IT 201900022029 A IT201900022029 A IT 201900022029A IT 201900022029 A1 IT201900022029 A1 IT 201900022029A1
Authority
IT
Italy
Prior art keywords
ophthalmic formulations
ophthalmic
formulations
Prior art date
Application number
IT102019000022029A
Other languages
English (en)
Inventor
Flavio Mantelli
Marco Maria Gentile
Maria Concetta Dragani
Original Assignee
Dompe Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farm Spa filed Critical Dompe Farm Spa
Priority to IT102019000022029A priority Critical patent/IT201900022029A1/it
Priority to DK20209808.3T priority patent/DK3827814T3/da
Priority to CN202011342111.2A priority patent/CN112826829A/zh
Priority to EP20209808.3A priority patent/EP3827814B1/en
Priority to FIEP20209808.3T priority patent/FI3827814T3/fi
Priority to LTEP20209808.3T priority patent/LT3827814T/lt
Priority to PT202098083T priority patent/PT3827814T/pt
Publication of IT201900022029A1 publication Critical patent/IT201900022029A1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
IT102019000022029A 2019-11-25 2019-11-25 Formulazioni oftalmiche IT201900022029A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT102019000022029A IT201900022029A1 (it) 2019-11-25 2019-11-25 Formulazioni oftalmiche
DK20209808.3T DK3827814T3 (da) 2019-11-25 2020-11-25 Ofthalmiske formuleringer
CN202011342111.2A CN112826829A (zh) 2019-11-25 2020-11-25 眼用制剂
EP20209808.3A EP3827814B1 (en) 2019-11-25 2020-11-25 Ophthalmic formulations
FIEP20209808.3T FI3827814T3 (fi) 2019-11-25 2020-11-25 Oftalmisia formulaatioita
LTEP20209808.3T LT3827814T (lt) 2019-11-25 2020-11-25 Oftalmologinės vaisto formos
PT202098083T PT3827814T (pt) 2019-11-25 2020-11-25 Formulações oftálmicas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000022029A IT201900022029A1 (it) 2019-11-25 2019-11-25 Formulazioni oftalmiche

Publications (1)

Publication Number Publication Date
IT201900022029A1 true IT201900022029A1 (it) 2021-05-25

Family

ID=69811802

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102019000022029A IT201900022029A1 (it) 2019-11-25 2019-11-25 Formulazioni oftalmiche

Country Status (7)

Country Link
EP (1) EP3827814B1 (it)
CN (1) CN112826829A (it)
DK (1) DK3827814T3 (it)
FI (1) FI3827814T3 (it)
IT (1) IT201900022029A1 (it)
LT (1) LT3827814T (it)
PT (1) PT3827814T (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119258198A (zh) * 2023-07-07 2025-01-07 重庆科润生物医药研发有限公司 一种含重组人神经生长因子的组合物及其应用和眼用制剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190224120A1 (en) * 2016-10-12 2019-07-25 Ps Therapies Ltd Drug vehicle compositions and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181279A (zh) * 2007-10-16 2008-05-21 黑龙江海昌生物技术有限公司 含海藻糖的人工泪液及其制备和应用方法
CN107913246A (zh) * 2016-10-09 2018-04-17 刘力 局部给药的眼用药物组合物
US10758571B1 (en) * 2019-04-09 2020-09-01 Combangio, Inc. Processes for making and using a mesenchymal stem cell derived secretome

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190224120A1 (en) * 2016-10-12 2019-07-25 Ps Therapies Ltd Drug vehicle compositions and methods of use thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ARAGONA P ET AL., THE SCIENTIFIC WORLD JOURNAL, vol. 2014, 2014, pages 9
JOHN STOLZ ET AL: "Trehalose: an intriguing disaccharide with potential for medical application in ophthalmology", CLINICAL OPHTHALMOLOGY, 1 May 2011 (2011-05-01), pages 577, XP055137154, DOI: 10.2147/OPTH.S18827 *
YEH S ET AL., INVEST OPHTHALMOL VIS SCI, 2003
ZEBO HUANGALAN TUNNACLIFFE, J PHYSIOL, vol. 558, 1 July 2004 (2004-07-01), pages 181 - 191

Also Published As

Publication number Publication date
CN112826829A (zh) 2021-05-25
LT3827814T (lt) 2026-02-10
EP3827814B1 (en) 2025-12-17
EP3827814A1 (en) 2021-06-02
PT3827814T (pt) 2026-01-20
DK3827814T3 (da) 2026-01-19
FI3827814T3 (fi) 2026-01-21

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