IT1401281B1 - Preparazione di coniugati fra derivati dell'adenina e proteine allergeniche e loro uso in immunoterapia specifica per il trattamento delle malattie allergiche. - Google Patents
Preparazione di coniugati fra derivati dell'adenina e proteine allergeniche e loro uso in immunoterapia specifica per il trattamento delle malattie allergiche.Info
- Publication number
- IT1401281B1 IT1401281B1 ITFI2010A000171A ITFI20100171A IT1401281B1 IT 1401281 B1 IT1401281 B1 IT 1401281B1 IT FI2010A000171 A ITFI2010A000171 A IT FI2010A000171A IT FI20100171 A ITFI20100171 A IT FI20100171A IT 1401281 B1 IT1401281 B1 IT 1401281B1
- Authority
- IT
- Italy
- Prior art keywords
- conjugates
- preparation
- treatment
- allergic diseases
- specific immunotherapy
- Prior art date
Links
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical class NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 title 1
- 230000002009 allergenic effect Effects 0.000 title 1
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/77—Ovalbumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Insects & Arthropods (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI2010A000171A IT1401281B1 (it) | 2010-08-05 | 2010-08-05 | Preparazione di coniugati fra derivati dell'adenina e proteine allergeniche e loro uso in immunoterapia specifica per il trattamento delle malattie allergiche. |
| EP11760560.0A EP2600899B1 (en) | 2010-08-05 | 2011-08-04 | Preparation of conjugates comprising adenine derivatives and allergenic proteins and their use for specific immunotherapy of allergenic diseases |
| US13/814,370 US8822407B2 (en) | 2010-08-05 | 2011-08-04 | Preparation of conjugates comprising adenine derivatives and allergenic proteins and their use for specific immunotherapy of allengenic diseases |
| PCT/IB2011/053482 WO2012017408A1 (en) | 2010-08-05 | 2011-08-04 | Preparation of conjugates comprising adenine derivatives and allergenic proteins and their use for specific immunotherapy of allergenic diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI2010A000171A IT1401281B1 (it) | 2010-08-05 | 2010-08-05 | Preparazione di coniugati fra derivati dell'adenina e proteine allergeniche e loro uso in immunoterapia specifica per il trattamento delle malattie allergiche. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITFI20100171A1 ITFI20100171A1 (it) | 2012-02-06 |
| IT1401281B1 true IT1401281B1 (it) | 2013-07-18 |
Family
ID=43529995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITFI2010A000171A IT1401281B1 (it) | 2010-08-05 | 2010-08-05 | Preparazione di coniugati fra derivati dell'adenina e proteine allergeniche e loro uso in immunoterapia specifica per il trattamento delle malattie allergiche. |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8822407B2 (it) |
| EP (1) | EP2600899B1 (it) |
| IT (1) | IT1401281B1 (it) |
| WO (1) | WO2012017408A1 (it) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2205573T3 (es) * | 1997-11-28 | 2004-05-01 | Sumitomo Pharmaceuticals Company, Limited | Nuevo compuestos heterociclicos. |
| EP1550662B1 (en) * | 2002-09-27 | 2012-07-04 | Dainippon Sumitomo Pharma Co., Ltd. | Adenine compound and use thereof |
-
2010
- 2010-08-05 IT ITFI2010A000171A patent/IT1401281B1/it active
-
2011
- 2011-08-04 WO PCT/IB2011/053482 patent/WO2012017408A1/en not_active Ceased
- 2011-08-04 US US13/814,370 patent/US8822407B2/en not_active Expired - Fee Related
- 2011-08-04 EP EP11760560.0A patent/EP2600899B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2600899A1 (en) | 2013-06-12 |
| WO2012017408A1 (en) | 2012-02-09 |
| US8822407B2 (en) | 2014-09-02 |
| US20130136764A1 (en) | 2013-05-30 |
| ITFI20100171A1 (it) | 2012-02-06 |
| EP2600899B1 (en) | 2014-06-25 |
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