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IT1392551B1 - Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica - Google Patents

Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica

Info

Publication number
IT1392551B1
IT1392551B1 ITTO2008A000870A ITTO20080870A IT1392551B1 IT 1392551 B1 IT1392551 B1 IT 1392551B1 IT TO2008A000870 A ITTO2008A000870 A IT TO2008A000870A IT TO20080870 A ITTO20080870 A IT TO20080870A IT 1392551 B1 IT1392551 B1 IT 1392551B1
Authority
IT
Italy
Prior art keywords
biomarcers
progression
diagnosis
detect
lateral sclerosis
Prior art date
Application number
ITTO2008A000870A
Other languages
English (en)
Inventor
Enrico M Bucci
Katarzyna Lis
Lorenza Franciosi
Tata Vincenzo De
Massimo Natale
Albo Alessandra Giuliano
Davide Corpillo
Original Assignee
Bioindustry Park Del Canavese S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioindustry Park Del Canavese S P A filed Critical Bioindustry Park Del Canavese S P A
Priority to ITTO2008A000870A priority Critical patent/IT1392551B1/it
Priority to EP09796795A priority patent/EP2356138A2/en
Priority to EP11193436A priority patent/EP2481749A1/en
Priority to US13/131,223 priority patent/US20130196924A1/en
Priority to PCT/IB2009/007580 priority patent/WO2010061283A2/en
Publication of ITTO20080870A1 publication Critical patent/ITTO20080870A1/it
Application granted granted Critical
Publication of IT1392551B1 publication Critical patent/IT1392551B1/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
ITTO2008A000870A 2008-11-25 2008-11-25 Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica IT1392551B1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITTO2008A000870A IT1392551B1 (it) 2008-11-25 2008-11-25 Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica
EP09796795A EP2356138A2 (en) 2008-11-25 2009-11-25 Biomarkers for diagnosing and detecting the progression of neurodegenerative disorders, in particular of amyotrophic lateral sclerosis
EP11193436A EP2481749A1 (en) 2008-11-25 2009-11-25 Biomarkers for diagnosing and detecting the progression of neurodegenerative disorders, in particular of amyotrophic lateral sclerosis
US13/131,223 US20130196924A1 (en) 2008-11-25 2009-11-25 Biomarkers for diagnosing and detecting the progression of neurodegenerative disorders, in particular of amyotrophic lateral sclerosis
PCT/IB2009/007580 WO2010061283A2 (en) 2008-11-25 2009-11-25 Biomarkers for diagnosing and detecting the progression of neurodegenerative disorders, in particular of amyotrophic lateral sclerosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITTO2008A000870A IT1392551B1 (it) 2008-11-25 2008-11-25 Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica

Publications (2)

Publication Number Publication Date
ITTO20080870A1 ITTO20080870A1 (it) 2010-05-26
IT1392551B1 true IT1392551B1 (it) 2012-03-09

Family

ID=41119531

Family Applications (1)

Application Number Title Priority Date Filing Date
ITTO2008A000870A IT1392551B1 (it) 2008-11-25 2008-11-25 Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica

Country Status (4)

Country Link
US (1) US20130196924A1 (it)
EP (2) EP2481749A1 (it)
IT (1) IT1392551B1 (it)
WO (1) WO2010061283A2 (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2240781B1 (en) 2008-01-18 2018-01-10 President and Fellows of Harvard College Methods of detecting signatures of disease or conditions in bodily fluids
CA2806291C (en) 2010-07-23 2023-08-29 President And Fellows Of Harvard College Methods for detecting signatures of disease or conditions in bodily fluids
EP2596353A4 (en) 2010-07-23 2014-01-15 Harvard College METHOD FOR DETECTING PRENATAL OR PREGNANT DISEASES OR SUFFERING
CA2806310A1 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods of detecting diseases or conditions using phagocytic cells
AU2011280997A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
WO2013022058A1 (ja) * 2011-08-10 2013-02-14 ニプロ株式会社 ビリルビン排泄促進剤
WO2013188828A1 (en) 2012-06-15 2013-12-19 Harry Stylli Methods of detecting diseases or conditions using circulating diseased cells
US20150275298A1 (en) 2012-06-15 2015-10-01 Harry Stylli Methods of detecting diseases or conditions
US11585814B2 (en) 2013-03-09 2023-02-21 Immunis.Ai, Inc. Methods of detecting prostate cancer
EP4202441A3 (en) 2013-03-09 2023-07-26 Immunis.AI, Inc. Gene expression profile in macrophages for the diagnosis of cancer
AU2015314813B2 (en) 2014-09-11 2022-02-24 Immunis.Ai, Inc. Methods of detecting prostate cancer
JP7076076B2 (ja) * 2016-03-03 2022-05-27 東亞合成株式会社 シグナルペプチドを指標にした筋萎縮性側索硬化症の診断方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8725529D0 (en) * 1987-10-30 1987-12-02 Delta Biotechnology Ltd Polypeptides
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
WO2001075177A2 (en) * 2000-04-03 2001-10-11 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tumor markers in ovarian cancer
US20030226155A1 (en) * 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
WO2004020583A2 (en) * 2002-08-27 2004-03-11 Bristol-Myers Squibb Company Polynucleotide predictor set for identifying protein tyrosine kinase modulators
US7268117B2 (en) * 2003-07-11 2007-09-11 Praecis Pharmaceuticals Incorporated Compositions, kits, and methods for identification, assessment, prevention, and therapy of endometriosis
GB0421639D0 (en) * 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
US20080289964A1 (en) * 2005-08-24 2008-11-27 Ira Leonard Goldknopf Assays for diagnosis and therapeutics employing similarities and differences in blood serum concentrations of 3 forms of complement C3c and related protein biomarkers between amyotrophic lateral sclerosis and Parkinson's disease
CA2626356C (en) 2005-10-21 2017-08-22 Catalyst Biosciences, Inc. Modified proteases that inhibit complement activation
US20080038224A1 (en) 2006-03-28 2008-02-14 Thierry Guyon Modified interferon-beta (IFN-beta) polypeptides
WO2007112940A2 (en) * 2006-03-31 2007-10-11 Ablynx N.V. Albumin-derived amino acid sequence, use thereof for increasing the half-life of therapeutic proteins and of other therapeutic compounds and entities, and constructs comprising the same
WO2008085024A1 (en) * 2007-01-12 2008-07-17 Erasmus University Medical Center Rotterdam Identification and detection of peptides relating to specific disorders

Also Published As

Publication number Publication date
EP2356138A2 (en) 2011-08-17
US20130196924A1 (en) 2013-08-01
EP2481749A1 (en) 2012-08-01
WO2010061283A3 (en) 2010-07-22
WO2010061283A2 (en) 2010-06-03
ITTO20080870A1 (it) 2010-05-26
WO2010061283A8 (en) 2011-07-07

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