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IT1204294B - Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato - Google Patents

Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato

Info

Publication number
IT1204294B
IT1204294B IT19693/86A IT1969386A IT1204294B IT 1204294 B IT1204294 B IT 1204294B IT 19693/86 A IT19693/86 A IT 19693/86A IT 1969386 A IT1969386 A IT 1969386A IT 1204294 B IT1204294 B IT 1204294B
Authority
IT
Italy
Prior art keywords
granulars
manufacture
production
controlled release
coated tablets
Prior art date
Application number
IT19693/86A
Other languages
English (en)
Other versions
IT8619693A0 (it
Inventor
Luciano Fontanelli
Original Assignee
Gentili Ist Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentili Ist Spa filed Critical Gentili Ist Spa
Priority to IT19693/86A priority Critical patent/IT1204294B/it
Publication of IT8619693A0 publication Critical patent/IT8619693A0/it
Priority to US07/020,450 priority patent/US4786506A/en
Priority to FR878703240A priority patent/FR2596649B1/fr
Priority to GB8705608A priority patent/GB2187643B/en
Priority to DE19873707571 priority patent/DE3707571A1/de
Application granted granted Critical
Publication of IT1204294B publication Critical patent/IT1204294B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
IT19693/86A 1986-03-11 1986-03-11 Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato IT1204294B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT19693/86A IT1204294B (it) 1986-03-11 1986-03-11 Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato
US07/020,450 US4786506A (en) 1986-03-11 1987-03-02 Method for the preparation of granulates suited for the production of sustained release coated tablets for oral use
FR878703240A FR2596649B1 (fr) 1986-03-11 1987-03-10 Procede de preparation de comprimes a effet entretenu pour usage oral, et comprimes ainsi obtenus
GB8705608A GB2187643B (en) 1986-03-11 1987-03-10 Method for the preparation of tablets slowly releasing the active principle
DE19873707571 DE3707571A1 (de) 1986-03-11 1987-03-10 Verfahren zur herstellung von granulaten, das geeignet ist zur produktion von zur lang andauernden freisetzung beschichteten tabletten zur oralen verwendung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19693/86A IT1204294B (it) 1986-03-11 1986-03-11 Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato

Publications (2)

Publication Number Publication Date
IT8619693A0 IT8619693A0 (it) 1986-03-11
IT1204294B true IT1204294B (it) 1989-03-01

Family

ID=11160428

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19693/86A IT1204294B (it) 1986-03-11 1986-03-11 Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato

Country Status (5)

Country Link
US (1) US4786506A (it)
DE (1) DE3707571A1 (it)
FR (1) FR2596649B1 (it)
GB (1) GB2187643B (it)
IT (1) IT1204294B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5268182A (en) * 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
DE3827214A1 (de) * 1988-08-11 1990-02-15 Roehm Gmbh Retardierte arzneiform und verfahren zu ihrer herstellung
IT1233163B (it) * 1989-03-01 1992-03-14 Zanchetta Aldo Procedimento di sferonizzazione e dispositivo per l'attuazione di detto procedimento
US5175003A (en) * 1990-04-06 1992-12-29 Biosytes Usa, Inc. Dual mechanism controlled release system for drug dosage forms
DE4140192C2 (de) * 1991-12-05 1996-02-29 Alfatec Pharma Gmbh Sol-gesteuerte Thermokolloidmatrix auf Gelatinebasis für perorale Retardformen
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
IT1270216B (it) * 1994-06-14 1997-04-29 Recordati Chem Pharm Metodo di stabilizzazione di composti biologicamente attivi mediante microgranuli ricoperti sospendibili in fluidi alimentari
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
ES2263211T3 (es) 1997-07-02 2006-12-01 Euro-Celtique S.A. Formulaciones de tramadol de liberacion sostenida estabilizada.
US6337091B1 (en) 1997-10-27 2002-01-08 Temple University - Of The Commonwealth System Of Higher Education Matrix for controlled delivery of highly soluble pharmaceutical agents
US6274162B1 (en) 2000-01-14 2001-08-14 Bpsi Holdings, Inc. Elegant film coating system
KR20040047747A (ko) * 2001-03-13 2004-06-05 펜웨스트 파머슈티칼즈 컴파니 변시치료 제형
AP2006003585A0 (en) * 2003-09-19 2006-04-30 Penwest Pharmaceuticals Co Delayed release dosage forms.
EP1663156A2 (en) * 2003-09-19 2006-06-07 Penwest Pharmaceuticals Company Chronotherapeutic dosage forms
CA2575988C (en) * 2004-08-04 2014-02-18 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
CA3018328A1 (en) 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT30380B (de) * 1906-09-26 1907-10-25 Siemens Ag Elektrische Kupplungsauswähleinrichtung für Eisenbahnsignale.
DE1467781A1 (de) * 1963-07-15 1968-12-05 Boehringer Sohn Ingelheim Verfahren zur Herstellung von Dragees mit verlaengerter Wirkstofffreigabe
US4132753A (en) * 1965-02-12 1979-01-02 American Cyanamid Company Process for preparing oral sustained release granules
US3400185A (en) * 1965-04-08 1968-09-03 Bristol Myers Co Agglomeration of smaller pharmaceutical particles into larger microspherules and enteic-coating thereof
US3453360A (en) * 1966-04-27 1969-07-01 Abbott Lab Universally useful stock material for manufacturing plastic dosage units by compression tableting processes
US3487138A (en) * 1966-11-23 1969-12-30 Merck & Co Inc Process for preparing a delayed release medicinal tablet
US3864469A (en) * 1967-12-16 1975-02-04 Hoechst Ag Xanthines in pharmaceutical preparations and for stabilization of vitamins
US3692896A (en) * 1968-06-14 1972-09-19 Isumura Juntendo Co Ltd Process for the preparation of water-soluble tablets
US3608030A (en) * 1969-05-21 1971-09-21 Howard Tint Method of preparing a tablet dosage-form for the immunization of the intestinal tract with live virus preparations
US3629393A (en) * 1969-09-11 1971-12-21 Nikken Chemicals Co Ltd Release-sustaining-tablet
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
US3836618A (en) * 1971-12-23 1974-09-17 American Home Prod Process for the uniform distribution of a drug on a granulated base
DE2251249A1 (de) * 1972-10-19 1974-05-02 Hoechst Ag Verfahren zur herstellung von penicillin-verbindungen enthaltenden tabletten
US4113816A (en) * 1973-07-12 1978-09-12 Choay S.A. Process for the manufacture of layered tablets incorporating controlled-release microcapsules
US3922339A (en) * 1974-06-20 1975-11-25 Kv Pharm Co Sustained release medicant
US4088798A (en) * 1975-11-11 1978-05-09 Sandoz, Inc. Methods for the preparation of controlled gastric residence time medicament formulations
FI63335B (fi) * 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
US4521402A (en) * 1983-01-03 1985-06-04 Verex Laboratories, Inc. Constant release rate solid oral dosage formulations of hydrazine
US4495177A (en) * 1983-01-17 1985-01-22 Shaklee Corporation Gel tableting agent
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
US4591496A (en) * 1984-01-16 1986-05-27 Massachusetts Institute Of Technology Process for making systems for the controlled release of macromolecules
HU191246B (en) * 1984-02-21 1987-01-28 Alkaloida Vegyeszeti Gyara,Hu Process for producing oral pharmaceutical compositions of retaed activity
DE3532692A1 (de) * 1985-09-13 1987-03-19 Boehringer Mannheim Gmbh Verfahren zum herstellen von tabletten aus pellets

Also Published As

Publication number Publication date
FR2596649A1 (fr) 1987-10-09
FR2596649B1 (fr) 1989-12-22
GB8705608D0 (en) 1987-04-15
IT8619693A0 (it) 1986-03-11
GB2187643B (en) 1990-02-14
US4786506A (en) 1988-11-22
DE3707571A1 (de) 1987-09-17
GB2187643A (en) 1987-09-16

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940330