IT1275420B - METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261 - Google Patents
METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261Info
- Publication number
- IT1275420B IT1275420B ITMI951155A ITMI951155A IT1275420B IT 1275420 B IT1275420 B IT 1275420B IT MI951155 A ITMI951155 A IT MI951155A IT MI951155 A ITMI951155 A IT MI951155A IT 1275420 B IT1275420 B IT 1275420B
- Authority
- IT
- Italy
- Prior art keywords
- tritium
- sch
- adenosine
- ligand
- receptor
- Prior art date
Links
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 title 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 title 1
- UTLPKQYUXOEJIL-UHFFFAOYSA-N LSM-3822 Chemical compound N1=CC=2C3=NC(C=4OC=CC=4)=NN3C(N)=NC=2N1CCC1=CC=CC=C1 UTLPKQYUXOEJIL-UHFFFAOYSA-N 0.000 title 1
- YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical compound [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 title 1
- 229960005305 adenosine Drugs 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 229910052722 tritium Inorganic materials 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
- G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD, ATP
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI951155A IT1275420B (en) | 1995-06-02 | 1995-06-02 | METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261 |
| PCT/EP1996/002348 WO1996038728A1 (en) | 1995-06-02 | 1996-06-01 | A METHOD FOR MEASURING THE A2a RECEPTOR BINDING ACTIVITY OF COMPOUNDS OF PHARMACOLOGICAL INTEREST BY THE USE OF THE TRITIATED LIGAND (3H)-SCH 58261 |
| AU61238/96A AU6123896A (en) | 1995-06-02 | 1996-06-01 | A method for measuring the a2a receptor binding activity of compounds of pharmacological interest by the use of the trit iated ligand (3h)-sch 58261 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI951155A IT1275420B (en) | 1995-06-02 | 1995-06-02 | METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI951155A0 ITMI951155A0 (en) | 1995-06-02 |
| ITMI951155A1 ITMI951155A1 (en) | 1996-12-02 |
| IT1275420B true IT1275420B (en) | 1997-08-05 |
Family
ID=11371733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI951155A IT1275420B (en) | 1995-06-02 | 1995-06-02 | METHOD FOR MEASURING THE BINDING AFFINITY TO THE A2A RECEPTOR OF ADENOSINE OF COMPONENTS OF PHARMACOLOGICAL INTEREST THROUGH THE USE OF THE TRITIUM LIGAND (3H) -SCH 58261 |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU6123896A (en) |
| IT (1) | IT1275420B (en) |
| WO (1) | WO1996038728A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6921825B2 (en) | 1998-09-16 | 2005-07-26 | King Pharmaceuticuals Research & Development, Inc. | Adenosine A3 receptor modulators |
| US6448253B1 (en) | 1998-09-16 | 2002-09-10 | King Pharmaceuticals Research And Development, Inc. | Adenosine A3 receptor modulators |
| GB0228723D0 (en) | 2002-12-09 | 2003-01-15 | Cambridge Biotechnology Ltd | Treatment of pain |
| GB0305150D0 (en) | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Use of therapeutic compounds |
| GB0305149D0 (en) | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Compounds for the treatment of pain |
| GB0305153D0 (en) * | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Identification of therapeutic compounds |
| PE20070521A1 (en) | 2005-09-23 | 2007-07-13 | Schering Corp | 7- [2- [4- (6-FLUORO-3-METHYL-1,2-BENZYSOXAZOL-5-IL) -1-PIPERAZINYL] ETHYL] -2- (1-PROPINYL) -7H-PIRAZOLE- [4, 3-E] - [1,2,4] -TRIAZOL- [1,5-C] -PYRIMIDIN-5-AMINE AS ANTAGONIST OF THE ADENOSINE A2a RECEPTOR |
| WO2018089901A2 (en) * | 2016-11-14 | 2018-05-17 | Joslin Diabetes Center | Exosome delivery system |
-
1995
- 1995-06-02 IT ITMI951155A patent/IT1275420B/en active IP Right Grant
-
1996
- 1996-06-01 AU AU61238/96A patent/AU6123896A/en not_active Abandoned
- 1996-06-01 WO PCT/EP1996/002348 patent/WO1996038728A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996038728A1 (en) | 1996-12-05 |
| AU6123896A (en) | 1996-12-18 |
| ITMI951155A1 (en) | 1996-12-02 |
| ITMI951155A0 (en) | 1995-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |