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IT1274571B - Procedimento per la preparazione di ¬r-(r*,r*)|-5-(3-clorofenil)-3- ¬2-(3,4-dimetossifenil)-1-metil-etil|-ossazolidin-2-one - Google Patents

Procedimento per la preparazione di ¬r-(r*,r*)|-5-(3-clorofenil)-3- ¬2-(3,4-dimetossifenil)-1-metil-etil|-ossazolidin-2-one

Info

Publication number
IT1274571B
IT1274571B ITMI951073A ITMI951073A IT1274571B IT 1274571 B IT1274571 B IT 1274571B IT MI951073 A ITMI951073 A IT MI951073A IT MI951073 A ITMI951073 A IT MI951073A IT 1274571 B IT1274571 B IT 1274571B
Authority
IT
Italy
Prior art keywords
soxzolidin
dimetoxyphenyl
chlorophenyl
ethyl
methyl
Prior art date
Application number
ITMI951073A
Other languages
English (en)
Inventor
Roberto Bortolaso
Mariano Stivanello
Original Assignee
Fabbrica Italiana Sintetici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fabbrica Italiana Sintetici Spa filed Critical Fabbrica Italiana Sintetici Spa
Priority to ITMI951073A priority Critical patent/IT1274571B/it
Publication of ITMI951073A0 publication Critical patent/ITMI951073A0/it
Priority to US08/632,076 priority patent/US5663360A/en
Publication of ITMI951073A1 publication Critical patent/ITMI951073A1/it
Application granted granted Critical
Publication of IT1274571B publication Critical patent/IT1274571B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ITMI951073A 1995-05-25 1995-05-25 Procedimento per la preparazione di ¬r-(r*,r*)|-5-(3-clorofenil)-3- ¬2-(3,4-dimetossifenil)-1-metil-etil|-ossazolidin-2-one IT1274571B (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITMI951073A IT1274571B (it) 1995-05-25 1995-05-25 Procedimento per la preparazione di ¬r-(r*,r*)|-5-(3-clorofenil)-3- ¬2-(3,4-dimetossifenil)-1-metil-etil|-ossazolidin-2-one
US08/632,076 US5663360A (en) 1995-05-25 1996-04-15 Process for preparing [R-(R*,R*)]-5-(3-chlorophenyl)-3-[2-(3,4-dimethoxylphenyl)-1-methyl-ethyl]-oxazolidin-2-one

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI951073A IT1274571B (it) 1995-05-25 1995-05-25 Procedimento per la preparazione di ¬r-(r*,r*)|-5-(3-clorofenil)-3- ¬2-(3,4-dimetossifenil)-1-metil-etil|-ossazolidin-2-one

Publications (3)

Publication Number Publication Date
ITMI951073A0 ITMI951073A0 (it) 1995-05-25
ITMI951073A1 ITMI951073A1 (it) 1996-11-25
IT1274571B true IT1274571B (it) 1997-07-17

Family

ID=11371672

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI951073A IT1274571B (it) 1995-05-25 1995-05-25 Procedimento per la preparazione di ¬r-(r*,r*)|-5-(3-clorofenil)-3- ¬2-(3,4-dimetossifenil)-1-metil-etil|-ossazolidin-2-one

Country Status (2)

Country Link
US (1) US5663360A (it)
IT (1) IT1274571B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7812149B2 (en) 1996-06-06 2010-10-12 Isis Pharmaceuticals, Inc. 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
US5898031A (en) 1996-06-06 1999-04-27 Isis Pharmaceuticals, Inc. Oligoribonucleotides for cleaving RNA
US9096636B2 (en) 1996-06-06 2015-08-04 Isis Pharmaceuticals, Inc. Chimeric oligomeric compounds and their use in gene modulation
WO2004044139A2 (en) 2002-11-05 2004-05-27 Isis Parmaceuticals, Inc. Modified oligonucleotides for use in rna interference
US8569474B2 (en) 2004-03-09 2013-10-29 Isis Pharmaceuticals, Inc. Double stranded constructs comprising one or more short strands hybridized to a longer strand
US8394947B2 (en) 2004-06-03 2013-03-12 Isis Pharmaceuticals, Inc. Positionally modified siRNA constructs
CA2568735A1 (en) * 2004-06-03 2005-12-22 Isis Pharmaceuticals, Inc. Double strand compositions comprising differentially modified strands for use in gene modulation
US7884086B2 (en) 2004-09-08 2011-02-08 Isis Pharmaceuticals, Inc. Conjugates for use in hepatocyte free uptake assays
AR057218A1 (es) * 2005-12-15 2007-11-21 Astra Ab Compuestos de oxazolidinona y su uso como pontenciadores del receptor metabotropico de glutamato
WO2010144293A1 (en) * 2009-06-08 2010-12-16 Merck Sharp & Dohme Corp. Synthesis of telcagepant and intermediates thereof
CN116987044B (zh) * 2023-09-28 2024-01-26 山东亿嘉农化有限公司 一种4－（对氯苯基）－2－三氟甲基－3－恶唑－5－酮的合成工艺

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5461163A (en) * 1994-06-06 1995-10-24 American Cyanamid Company Synthesis and purification of [R-(R*,R*)]-5-[2-[5-(3-chloro-phenyl)-2-oxo-3-oxazolidinyl]-propyl]-1,-3-benzodiozole-2,2-dicarboxylic acid dimethyl ester

Also Published As

Publication number Publication date
US5663360A (en) 1997-09-02
ITMI951073A0 (it) 1995-05-25
ITMI951073A1 (it) 1996-11-25

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Legal Events

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0001 Granted