IT1271001B - Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus - Google Patents
Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcusInfo
- Publication number
- IT1271001B IT1271001B ITMI941594A ITMI941594A IT1271001B IT 1271001 B IT1271001 B IT 1271001B IT MI941594 A ITMI941594 A IT MI941594A IT MI941594 A ITMI941594 A IT MI941594A IT 1271001 B IT1271001 B IT 1271001B
- Authority
- IT
- Italy
- Prior art keywords
- hyaluronic acid
- preparation procedure
- acid preparation
- streptococcus
- fermentation
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- 241000194017 Streptococcus Species 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 title 1
- 230000004151 fermentation Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Si descrive un procedimento di preparazione di acido ialuronico mediante coltura sommersa di un microrganismo del genere Streptococcus.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI941594A IT1271001B (it) | 1994-07-26 | 1994-07-26 | Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus |
| EP95111587A EP0694616A3 (en) | 1994-07-26 | 1995-07-24 | Process for the preparation of hyaluronic acid by fermentation with streptococcus |
| JP7250023A JPH0956394A (ja) | 1994-07-26 | 1995-08-23 | 連鎖球菌を用いた発酵によるヒアルロン酸の製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI941594A IT1271001B (it) | 1994-07-26 | 1994-07-26 | Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus |
| JP7250023A JPH0956394A (ja) | 1994-07-26 | 1995-08-23 | 連鎖球菌を用いた発酵によるヒアルロン酸の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI941594A0 ITMI941594A0 (it) | 1994-07-26 |
| ITMI941594A1 ITMI941594A1 (it) | 1996-01-26 |
| IT1271001B true IT1271001B (it) | 1997-05-26 |
Family
ID=26331179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI941594A IT1271001B (it) | 1994-07-26 | 1994-07-26 | Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0694616A3 (it) |
| JP (1) | JPH0956394A (it) |
| IT (1) | IT1271001B (it) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH692919A5 (fr) | 1999-01-28 | 2002-12-13 | Trb Chemedica S A | Procédé de purification de l'acide hyaluronique à poids moléculaire élevé. |
| BR0215220A (pt) | 2001-12-21 | 2007-01-09 | Novozymes Biopolymer As | método para produzir um ácido hialurÈnico, célula hospedeira de bacillus, construção de ácido nucléico, seqüência de ácido nucléico isolada, vetor de expressão , vetor de expressão recombinante, célula hospedeira recombinante, método para produzir um polipeptìdeo, e, polipeptìdeo isolado |
| BRPI0614885A2 (pt) | 2005-08-25 | 2011-04-19 | Toyo Boseki | planta produtora de ácido hialurÈnico |
| EP1772052A1 (de) | 2005-10-05 | 2007-04-11 | Bayer CropScience GmbH | Verbesserte Verfahren und Mittel zur Herstellung von Hyaluronan |
| WO2008004530A1 (en) * | 2006-07-03 | 2008-01-10 | Kyowa Hakko Bio Co., Ltd. | Powder of hyaluronic acid or salt thereof, and method for producing the same |
| CN101512006B (zh) | 2006-07-06 | 2012-04-11 | 利莱恩斯生命科学有限公司 | 用于纯化高分子量透明质酸的有效方法 |
| WO2008014787A1 (en) | 2006-08-04 | 2008-02-07 | Novozymes Biopolymer A/S | Branched hyaluronic acid and method of manufacture |
| JP2008280430A (ja) * | 2007-05-10 | 2008-11-20 | Mitsubishi Rayon Co Ltd | ヒアルロン酸の製造方法 |
| EP2036983A1 (de) | 2007-09-12 | 2009-03-18 | Bayer CropScience AG | Pflanzen, die erhöhte Mengen an Glucosaminglycanen synthetisieren |
| US9109051B2 (en) | 2007-12-19 | 2015-08-18 | Evonik Goldschmidt Gmbh | Crosslinked hyaluronic acid in emulsion |
| EP2213315A1 (en) | 2009-01-30 | 2010-08-04 | Mero S.r.L. | Antibacterial hydrogel and use thereof in orthopedics |
| IT1401498B1 (it) | 2010-07-30 | 2013-07-26 | Mero Srl | Idrogelo a base di acido ialuronico e suo uso in ortopedia |
| WO2013030348A1 (en) | 2011-09-02 | 2013-03-07 | Novozymes Biopharma Dk A/S | Oral formulations containing hyaluronic acid for sustained drug release |
| WO2014100837A1 (en) | 2012-12-17 | 2014-06-26 | Bui The Duy | Computer aided implantation of body implants |
| EP2985027B1 (en) | 2014-08-16 | 2021-03-31 | Church & Dwight Co., Inc. | Nasal composition comprising mixture of hyaluronic acids and saline solution |
| EP2985019B1 (en) | 2014-08-16 | 2021-10-20 | Church & Dwight Co., Inc. | Nasal composition having anti-viral properties |
| JP2017112901A (ja) * | 2015-12-24 | 2017-06-29 | キッコーマン株式会社 | 高分子ヒアルロン酸の製造方法 |
| EP3572068A1 (en) * | 2018-05-22 | 2019-11-27 | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. | New salt of cysteamine for the preparation of highly respirable particles |
| RU2719140C1 (ru) | 2019-07-26 | 2020-04-17 | Общество с ограниченной ответственностью "ЦЕНТР ТРАНСФЕРА БИОТЕХНОЛОГИЙ ОКА-Биотех" | Бактерия рода bacillus, продуцирующая гиалуроновую кислоту, и способ получения гиалуроновой кислоты с использованием указанной бактерии |
| CN116874637A (zh) * | 2020-11-20 | 2023-10-13 | 广东双骏生物科技有限公司 | 一种从微生物发酵液中分离纯化透明质酸的方法 |
| CN112592849A (zh) * | 2020-12-14 | 2021-04-02 | 宁夏泰胜生物科技有限公司 | 利用兽疫链霉菌发酵生产高分子量透明质酸的培养基和培养方法 |
| EP4487863A1 (en) | 2023-07-07 | 2025-01-08 | NuPep AS | Consensus peptides in hya for use in treating degenerated joints |
| EP4487834A1 (en) | 2023-07-07 | 2025-01-08 | NuPep AS | Consensus peptides in hya |
| WO2025012149A1 (en) | 2023-07-07 | 2025-01-16 | Nupep As | Consensus peptides in hya |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5316926A (en) * | 1983-11-25 | 1994-05-31 | Miles Inc. | Method for the microbiological production of non-antigenic hyaluronic acid |
| US5023175A (en) * | 1986-05-01 | 1991-06-11 | Kabushiki Kaisha Yakult Honsha | Novel production process of hyaluronic acid and bacterium strain therefor |
| US4897349A (en) * | 1989-04-28 | 1990-01-30 | Medchem Products, Inc. | Biosynthesis of hyaluronic acid |
| GB9024223D0 (en) * | 1990-11-07 | 1990-12-19 | Fermentech Ltd | Production of hyaluronic acid |
-
1994
- 1994-07-26 IT ITMI941594A patent/IT1271001B/it active IP Right Grant
-
1995
- 1995-07-24 EP EP95111587A patent/EP0694616A3/en not_active Withdrawn
- 1995-08-23 JP JP7250023A patent/JPH0956394A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI941594A0 (it) | 1994-07-26 |
| EP0694616A2 (en) | 1996-01-31 |
| ITMI941594A1 (it) | 1996-01-26 |
| EP0694616A3 (en) | 1998-08-05 |
| JPH0956394A (ja) | 1997-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970729 |