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IT1264061B - Procedimento di produzione di un nucleotide 5. - Google Patents

Procedimento di produzione di un nucleotide 5.

Info

Publication number
IT1264061B
IT1264061B ITTO930501A ITTO930501A IT1264061B IT 1264061 B IT1264061 B IT 1264061B IT TO930501 A ITTO930501 A IT TO930501A IT TO930501 A ITTO930501 A IT TO930501A IT 1264061 B IT1264061 B IT 1264061B
Authority
IT
Italy
Prior art keywords
nucleotide
production
nucleoside
suspension
nucleosides
Prior art date
Application number
ITTO930501A
Other languages
English (en)
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ITTO930501A0 publication Critical patent/ITTO930501A0/it
Publication of ITTO930501A1 publication Critical patent/ITTO930501A1/it
Application granted granted Critical
Publication of IT1264061B publication Critical patent/IT1264061B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procedimento per la produzione di un nucleotide 5', che consiste nel mantenere una sospensione di nucleoside in un solvente organico ad una temperatura non inferiore a circa 20°C e nel sottoporre quindi la sospensione risultante ad una fosforilazione dei nucleosidi.Secondo la presente invenzione, un nucleotide 5' può essere prodotto da un nucleoside con elevata purezza ed elevata resa in un tempo di reazione abbreviato, e la rimozione delle impurezze nel processo di purificazione del nucleotide viene effettuata facilmente.
ITTO930501A 1992-07-08 1993-07-07 Procedimento di produzione di un nucleotide 5. IT1264061B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18114592 1992-07-08

Publications (3)

Publication Number Publication Date
ITTO930501A0 ITTO930501A0 (it) 1993-07-07
ITTO930501A1 ITTO930501A1 (it) 1995-01-07
IT1264061B true IT1264061B (it) 1996-09-09

Family

ID=16095679

Family Applications (1)

Application Number Title Priority Date Filing Date
ITTO930501A IT1264061B (it) 1992-07-08 1993-07-07 Procedimento di produzione di un nucleotide 5.

Country Status (7)

Country Link
US (1) US5623069A (it)
KR (1) KR100270246B1 (it)
CN (1) CN1033272C (it)
CA (1) CA2100027C (it)
ES (1) ES2055670B1 (it)
IT (1) IT1264061B (it)
TW (1) TW279165B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101665525B (zh) * 2009-09-10 2013-05-01 广东肇庆星湖生物科技股份有限公司 一种核苷酸的合成方法
CN101891772B (zh) * 2010-07-16 2012-11-28 广东肇庆星湖生物科技股份有限公司 一种5’-核苷酸二钠的制备方法
CN101914125A (zh) * 2010-08-12 2010-12-15 广东肇庆星湖生物科技股份有限公司 一种5’-鸟苷磷酸化反应液的萃取工艺
CN104151383A (zh) * 2014-07-15 2014-11-19 南通香地生物有限公司 尿苷酸二钠盐的生产方法
CN114315934A (zh) * 2021-12-22 2022-04-12 成都市海通药业有限公司 一种胞磷胆碱重要中间体胞苷酸的合成和精制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1645896C3 (de) * 1965-03-17 1975-01-02 Ajinomoto Co., Inc., Tokio Verfahren zur Herstellung von 5'-Ribonucleotiden nd S'-Desoxyribonucleotiden
DE1620568A1 (de) * 1965-10-04 1970-08-27 Takeda Chemical Industries Ltd Verfahren zur Herstellung von Nucleotiden
US3433783A (en) * 1967-07-03 1969-03-18 Takeda Chemical Industries Ltd Method for the production of ribonucleoside-5'-phosphate
JPS5980694A (ja) * 1982-10-30 1984-05-10 Seikagaku Kogyo Co Ltd リン酸化合物の製造方法
JPS59163397A (ja) * 1983-03-09 1984-09-14 Seikagaku Kogyo Co Ltd リン酸化合物の製造方法
JPS59167599A (ja) * 1983-03-11 1984-09-21 Takeda Chem Ind Ltd イノシンおよびグアノシンの化学的リン酸化法
JP2671446B2 (ja) * 1988-10-25 1997-10-29 味の素株式会社 イノシン及びグアノシンの混合リン酸化方法

Also Published As

Publication number Publication date
CA2100027A1 (en) 1994-01-09
ITTO930501A1 (it) 1995-01-07
ES2055670B1 (es) 1995-02-16
KR100270246B1 (ko) 2000-10-16
ES2055670A1 (es) 1994-08-16
CN1086219A (zh) 1994-05-04
KR940005659A (ko) 1994-03-22
CA2100027C (en) 2003-10-07
US5623069A (en) 1997-04-22
ITTO930501A0 (it) 1993-07-07
TW279165B (it) 1996-06-21
CN1033272C (zh) 1996-11-13

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