IT1263144B - PHARMACEUTICAL COMPOSITIONS INCLUDING SPONGY MATERIAL CONSTITUTED FROM FOREIGN DERIVATIVES OF HYALURONIC ACID IN ASSOCIATION WITH OTHER PHARMACOLOGICALLY ACTIVE SUBSTANCES - Google Patents
PHARMACEUTICAL COMPOSITIONS INCLUDING SPONGY MATERIAL CONSTITUTED FROM FOREIGN DERIVATIVES OF HYALURONIC ACID IN ASSOCIATION WITH OTHER PHARMACOLOGICALLY ACTIVE SUBSTANCESInfo
- Publication number
- IT1263144B IT1263144B ITMI930182A ITMI930182A IT1263144B IT 1263144 B IT1263144 B IT 1263144B IT MI930182 A ITMI930182 A IT MI930182A IT MI930182 A ITMI930182 A IT MI930182A IT 1263144 B IT1263144 B IT 1263144B
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical compositions
- hyaluronic acid
- active substances
- pharmacologically active
- association
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 2
- 239000000463 material Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- -1 ester derivatives of hyaluronic acid Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002406 microsurgery Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invenzione si riferisce a nuove composizioni farmaceutiche comprendenti materiale spugnoso costituito da derivati esterei totali o parziali dell'acido ialuronico, da soli o in miscela tra loro, co-liofilizzato con una soluzione conte-nente altre sostanze farmacologicamente attive, al loro processo di produzione ed al loro impiego in chirurgia ed in particolare nella microchirurgia.The present invention relates to new pharmaceutical compositions comprising spongy material consisting of total or partial ester derivatives of hyaluronic acid, alone or in a mixture with each other, co-freeze-dried with a solution containing other pharmacologically active substances, to their process of production and their use in surgery and in particular in microsurgery.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI930182A IT1263144B (en) | 1993-02-04 | 1993-02-04 | PHARMACEUTICAL COMPOSITIONS INCLUDING SPONGY MATERIAL CONSTITUTED FROM FOREIGN DERIVATIVES OF HYALURONIC ACID IN ASSOCIATION WITH OTHER PHARMACOLOGICALLY ACTIVE SUBSTANCES |
| PCT/EP1994/000294 WO1994017840A1 (en) | 1993-02-04 | 1994-02-02 | Pharmaceutical compositions comprising a spongy material consisting of ester derivatives of hyaluronic acid combined with other pharmacologically active substances |
| EP94906201A EP0682534A1 (en) | 1993-02-04 | 1994-02-02 | Pharmaceutical compositions comprising a spongy material consisting of ester derivatives of hyaluronic acid combined with other pharmacologically active substances |
| JP6517622A JPH08506497A (en) | 1993-02-04 | 1994-02-02 | Pharmaceutical composition comprising a sponge-like material consisting of an ester derivative of hyaluronic acid in combination with other pharmaceutically active substances |
| KR1019950703218A KR960700766A (en) | 1993-02-04 | 1994-02-02 | Pharmaceutical composition consisting of sponge material in which ester derivative of hyaluronic acid is combined with other pharmaceutically effective substances |
| CA002155518A CA2155518A1 (en) | 1993-02-04 | 1994-02-02 | Pharmaceutical compositions comprising a spongy material consisting of ester derivatives of hyarulonic acid combined with other pharmacologically active substances |
| AU60014/94A AU6001494A (en) | 1993-02-04 | 1994-02-02 | Pharmaceutical compositions comprising a spongy material consisting of ester derivatives of hyaluronic acid combined with other pharmacologically active substances |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI930182A IT1263144B (en) | 1993-02-04 | 1993-02-04 | PHARMACEUTICAL COMPOSITIONS INCLUDING SPONGY MATERIAL CONSTITUTED FROM FOREIGN DERIVATIVES OF HYALURONIC ACID IN ASSOCIATION WITH OTHER PHARMACOLOGICALLY ACTIVE SUBSTANCES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI930182A0 ITMI930182A0 (en) | 1993-02-04 |
| ITMI930182A1 ITMI930182A1 (en) | 1994-08-04 |
| IT1263144B true IT1263144B (en) | 1996-08-01 |
Family
ID=11364858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI930182A IT1263144B (en) | 1993-02-04 | 1993-02-04 | PHARMACEUTICAL COMPOSITIONS INCLUDING SPONGY MATERIAL CONSTITUTED FROM FOREIGN DERIVATIVES OF HYALURONIC ACID IN ASSOCIATION WITH OTHER PHARMACOLOGICALLY ACTIVE SUBSTANCES |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0682534A1 (en) |
| JP (1) | JPH08506497A (en) |
| KR (1) | KR960700766A (en) |
| AU (1) | AU6001494A (en) |
| CA (1) | CA2155518A1 (en) |
| IT (1) | IT1263144B (en) |
| WO (1) | WO1994017840A1 (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997045532A1 (en) * | 1996-05-28 | 1997-12-04 | Brown University Research Foundation | Hyaluronan based biodegradable scaffolds for tissue repair |
| US6596703B1 (en) | 1997-07-11 | 2003-07-22 | Jagotec Ag | Promotion of wound healing utilizing steroids having reduced deteriorous systemic side effects typical of glucocorticoids, mineralocorticoids and sex steroids |
| US6872819B1 (en) * | 1998-05-27 | 2005-03-29 | Fidia Advanced Biopolymers S.R.L. | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| JP4273450B2 (en) * | 2000-12-07 | 2009-06-03 | 有限会社テクノサージ | Tissue regeneration substrate, transplant material, and production method thereof |
| EP1369441A4 (en) * | 2001-01-31 | 2004-12-08 | Seikagaku Kogyo Co Ltd | Crosslinked polysaccharide sponge |
| US7238677B2 (en) * | 2003-03-28 | 2007-07-03 | Kimberly-Clark Worldwide, Inc. | Prevention of urogenital infections |
| US8021684B2 (en) * | 2004-07-09 | 2011-09-20 | Ferrosan Medical Devices A/S | Haemostatic composition comprising hyaluronic acid |
| JP4754532B2 (en) * | 2007-07-09 | 2011-08-24 | 生化学工業株式会社 | A therapeutic agent containing hyaluronic acid oligosaccharide as an active ingredient |
| US8642831B2 (en) | 2008-02-29 | 2014-02-04 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
| US11109849B2 (en) | 2012-03-06 | 2021-09-07 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
| BR112014030962A2 (en) | 2012-06-12 | 2017-06-27 | Ferrosan Medical Devices As | methods for preparing and reconstituting a dry composition suitable for use in haemostasis and wound healing, and hemostatic kit |
| EP3010419B1 (en) | 2013-06-21 | 2020-05-20 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
| JP6489485B2 (en) | 2013-12-11 | 2019-03-27 | フェロサン メディカル デバイシーズ エイ/エス | Dry composition containing an extrusion enhancing factor |
| EP3206726B1 (en) | 2014-10-13 | 2020-05-27 | Ferrosan Medical Devices A/S | Dry composition for use in haemostasis and wound healing |
| CN107206165B (en) | 2014-12-24 | 2020-10-23 | 弗罗桑医疗设备公司 | Syringe for holding and mixing first and second substances |
| JP6747651B2 (en) | 2015-07-03 | 2020-08-26 | フェロサン メディカル デバイシーズ エイ/エス | Syringe for holding vacuum in storage and for mixing two components |
| WO2019215274A1 (en) | 2018-05-09 | 2019-11-14 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229075B (en) * | 1985-04-05 | 1991-07-17 | Fidia Farmaceutici | Topical compsn. contg. hyaluronic acid deriv. as vehicle |
| US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| IT1219587B (en) * | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | SELF-CROSS-LINKED CARBOXYLY POLYSACCHARIDES |
| IT1248934B (en) * | 1990-06-01 | 1995-02-11 | Fidia Spa | BIOCOMPATIBLE PERFORATED MEMBRANES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS A SUPPORT FOR THE IN VITRO GROWTH OF EPITHELIAL CELLS, ARTIFICIAL LEATHER THUS OBTAINED AND THEIR USE IN LEATHER TRANSPLANTS |
| IT1247472B (en) * | 1991-05-31 | 1994-12-17 | Fidia Spa | PROCESS FOR THE PREPARATION OF MICROSPHERES CONTAINING BIOLOGICALLY ACTIVE COMPONENTS. |
| IT1251151B (en) * | 1991-08-05 | 1995-05-04 | Fidia Spa | SPONGY MATERIAL ESSENTIALLY CONSTITUTED BY HYALURONIC ACID, OR ITS DERIVATIVES |
| IT1260154B (en) * | 1992-07-03 | 1996-03-28 | Lanfranco Callegaro | HYALURONIC ACID AND ITS DERIVATIVES IN INTERPENETRATING POLYMERS (IPN) |
-
1993
- 1993-02-04 IT ITMI930182A patent/IT1263144B/en active IP Right Grant
-
1994
- 1994-02-02 WO PCT/EP1994/000294 patent/WO1994017840A1/en not_active Ceased
- 1994-02-02 AU AU60014/94A patent/AU6001494A/en not_active Abandoned
- 1994-02-02 CA CA002155518A patent/CA2155518A1/en not_active Abandoned
- 1994-02-02 JP JP6517622A patent/JPH08506497A/en active Pending
- 1994-02-02 KR KR1019950703218A patent/KR960700766A/en not_active Withdrawn
- 1994-02-02 EP EP94906201A patent/EP0682534A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0682534A1 (en) | 1995-11-22 |
| KR960700766A (en) | 1996-02-24 |
| ITMI930182A1 (en) | 1994-08-04 |
| WO1994017840A1 (en) | 1994-08-18 |
| ITMI930182A0 (en) | 1993-02-04 |
| CA2155518A1 (en) | 1994-08-18 |
| JPH08506497A (en) | 1996-07-16 |
| AU6001494A (en) | 1994-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970227 |