IT1261688B - Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. - Google Patents
Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.Info
- Publication number
- IT1261688B IT1261688B ITRM930356A ITRM930356A IT1261688B IT 1261688 B IT1261688 B IT 1261688B IT RM930356 A ITRM930356 A IT RM930356A IT RM930356 A ITRM930356 A IT RM930356A IT 1261688 B IT1261688 B IT 1261688B
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- pharmaceutical compositions
- oxydride
- produce pharmaceutical
- skin diseases
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000017520 skin disease Diseases 0.000 title 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 150000001991 dicarboxylic acids Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 206010021198 ichthyosis Diseases 0.000 abstract 1
- -1 linoleic Chemical class 0.000 abstract 1
- 150000002763 monocarboxylic acids Chemical class 0.000 abstract 1
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- 150000003047 pimelic acids Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 150000003330 sebacic acids Chemical class 0.000 abstract 1
- 150000003442 suberic acids Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Birds (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
Viene descritto l'uso di esteri sull'ossidrile della L-carnitina con acidi bicarbossilici saturi (ad es. acido azelaico, sebacico, suberico e pimelico) o con acidi monocarbossilici insaturi (ad es. acido linoleico, linolenico, oleico e arachidonico) per produrre composizioni farmaceutiche atte all'applicazione topica per il trattamento di affezioni cutanee, quali ad esempio ittiosi e psoriasi.
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM930356A IT1261688B (it) | 1993-05-28 | 1993-05-28 | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
| EP94108015A EP0628309B1 (en) | 1993-05-28 | 1994-05-25 | Use of O-esters of L-carnitine for the treatment of dermatoses |
| ES94108015T ES2130304T3 (es) | 1993-05-28 | 1994-05-25 | Empleo de o-esteres de l-carnitina para el tratamiento de dermatosis. |
| AT94108015T ATE177947T1 (de) | 1993-05-28 | 1994-05-25 | Verwendung von l-carnitin-o-estern zur behandlung der dermatosen |
| DE69417290T DE69417290T2 (de) | 1993-05-28 | 1994-05-25 | Verwendung von L-Carnitin-O-Estern zur Behandlung der Dermatosen |
| DK94108015T DK0628309T3 (da) | 1993-05-28 | 1994-05-25 | Anvendelse af O-estere af L-carnitin til behandling af dermatoser |
| CA002124402A CA2124402A1 (en) | 1993-05-28 | 1994-05-26 | Use of o-esters of l-carnitine for producing pharmaceutical compositions for the treatment of dermatoses |
| ZA943727A ZA943727B (en) | 1993-05-28 | 1994-05-26 | Use of o-esters of l-carnitine for producing pharmaceutical compositions for the reatment of dermatoses |
| JP6115025A JPH0748328A (ja) | 1993-05-28 | 1994-05-27 | L−カルニチンのo−エステル類を含む皮膚病処置のための医薬組成物 |
| US08/250,686 US5494924A (en) | 1993-05-28 | 1994-05-27 | Therapeutical method for the treatment of dermatoses using O-esters of L-carnitine |
| TW083105639A TW288976B (it) | 1993-05-28 | 1994-06-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM930356A IT1261688B (it) | 1993-05-28 | 1993-05-28 | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM930356A0 ITRM930356A0 (it) | 1993-05-28 |
| ITRM930356A1 ITRM930356A1 (it) | 1994-11-28 |
| IT1261688B true IT1261688B (it) | 1996-05-29 |
Family
ID=11401786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM930356A IT1261688B (it) | 1993-05-28 | 1993-05-28 | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5494924A (it) |
| EP (1) | EP0628309B1 (it) |
| JP (1) | JPH0748328A (it) |
| AT (1) | ATE177947T1 (it) |
| CA (1) | CA2124402A1 (it) |
| DE (1) | DE69417290T2 (it) |
| DK (1) | DK0628309T3 (it) |
| ES (1) | ES2130304T3 (it) |
| IT (1) | IT1261688B (it) |
| TW (1) | TW288976B (it) |
| ZA (1) | ZA943727B (it) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
| US5667791A (en) * | 1996-05-31 | 1997-09-16 | Thione International, Inc. | X-ray induced skin damage protective composition |
| NZ335495A (en) | 1996-11-12 | 2002-03-28 | Dov Tamarkin | alpha,omega-dicarboxylic acid esters and their use in treating dermatological disorders |
| IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
| IT1291126B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine |
| IT1291133B1 (it) * | 1997-04-07 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio tartrato |
| IT1291134B1 (it) | 1997-04-08 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizioni solide atte alla somministrazione orale comprendenti una alcanoil l-carnitina magnesio citrato |
| IT1291143B1 (it) * | 1997-04-18 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina |
| IT1290600B1 (it) * | 1997-04-30 | 1998-12-10 | Sigma Tau Ind Farmaceuti | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio fumarato |
| US6138683A (en) * | 1997-09-19 | 2000-10-31 | Thione International, Inc. | Smokeless tobacco products containing antioxidants |
| US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
| US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
| US5922346A (en) * | 1997-12-01 | 1999-07-13 | Thione International, Inc. | Antioxidant preparation |
| ATE254923T1 (de) | 1998-03-19 | 2003-12-15 | Sigma Tau Ind Farmaceuti | Kombinierte zusammensetzung bestehend aus l- karnitin oder l-alkanoylkarnitin, einem glycosaminoglycan und/oder einem seiner bestandteile |
| US6242491B1 (en) * | 1999-06-25 | 2001-06-05 | Rima Kaddurah-Daouk | Use of creatine or creatine compounds for skin preservation |
| US20040198821A1 (en) * | 2002-01-29 | 2004-10-07 | Hwang Cheng Shine | Reduction of hair growth |
| CA2436650A1 (en) * | 2003-08-06 | 2005-02-06 | Naturia Inc. | Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses |
| CN1960698A (zh) * | 2004-05-31 | 2007-05-09 | 昭和电工株式会社 | 含肉碱衍生物的局部减肥制剂和化妆品 |
| ES2336995B1 (es) | 2008-10-13 | 2011-02-09 | Lipotec, S.A. | Composicion cosmetica o dermofarmaceutica para el cuidado de la piel,cuero cabelludo y uñas. |
| US9259343B2 (en) | 2012-07-06 | 2016-02-16 | Newman Technologies LLC | Device for mitigating plantar fasciitis |
| US20140316156A1 (en) * | 2013-04-18 | 2014-10-23 | Deborah Warner | Method of producing therapeutic agent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1156840B (it) * | 1978-06-27 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Acil derivati della carnitina |
| IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
| FR2654619B1 (fr) * | 1989-11-23 | 1992-01-31 | Sederma Sa | Utilisation en cosmetique de composes destines a optimiser la penetration des principes actifs. |
| IT1263013B (it) * | 1992-10-20 | 1996-07-23 | Avantgarde Spa | Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee. |
-
1993
- 1993-05-28 IT ITRM930356A patent/IT1261688B/it active IP Right Grant
-
1994
- 1994-05-25 AT AT94108015T patent/ATE177947T1/de not_active IP Right Cessation
- 1994-05-25 EP EP94108015A patent/EP0628309B1/en not_active Expired - Lifetime
- 1994-05-25 ES ES94108015T patent/ES2130304T3/es not_active Expired - Lifetime
- 1994-05-25 DE DE69417290T patent/DE69417290T2/de not_active Expired - Fee Related
- 1994-05-25 DK DK94108015T patent/DK0628309T3/da active
- 1994-05-26 ZA ZA943727A patent/ZA943727B/xx unknown
- 1994-05-26 CA CA002124402A patent/CA2124402A1/en not_active Abandoned
- 1994-05-27 JP JP6115025A patent/JPH0748328A/ja active Pending
- 1994-05-27 US US08/250,686 patent/US5494924A/en not_active Expired - Fee Related
- 1994-06-20 TW TW083105639A patent/TW288976B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM930356A0 (it) | 1993-05-28 |
| ATE177947T1 (de) | 1999-04-15 |
| JPH0748328A (ja) | 1995-02-21 |
| EP0628309B1 (en) | 1999-03-24 |
| DE69417290T2 (de) | 1999-08-19 |
| ZA943727B (en) | 1995-02-02 |
| TW288976B (it) | 1996-10-21 |
| CA2124402A1 (en) | 1994-11-29 |
| ES2130304T3 (es) | 1999-07-01 |
| ITRM930356A1 (it) | 1994-11-28 |
| EP0628309A1 (en) | 1994-12-14 |
| DE69417290D1 (de) | 1999-04-29 |
| DK0628309T3 (da) | 1999-10-11 |
| US5494924A (en) | 1996-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1261688B (it) | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. | |
| IT1261984B (it) | Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. | |
| ATE106867T1 (de) | 13-trans-retinsäureester. | |
| IT8567584A0 (it) | Procedimento per la produzione di esteri dell acido acrilico e metacrilico mediante esterificazione | |
| IT1263013B (it) | Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee. | |
| IT8567583A1 (it) | Procedimento per la produzione di esteri dell'acido acrilico e metacrilico mediante esterificazione. | |
| IT1256450B (it) | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione | |
| IT8523049A0 (it) | Da esteri e da ammidi di inibitori della renina costituiti amminoacidi. | |
| DE59504267D1 (de) | Härten von ungesättigten fetten, fettsäuren oder fettsäureestern | |
| ES2111355T3 (es) | Sal de l-carnitina y composiciones cosmeticas y farmaceuticas que la contienen para el tratamiento de dermatosis. | |
| AU554413B2 (en) | Linoleic acid and essential fatty acid compositions as | |
| EP0139480A3 (en) | Topical preparations containing tars and fatty acids | |
| DE3468021D1 (en) | Imidazol-2-yl mercapto alkanoic acids, process for producing the same and pharmaceutical preparations containing the same | |
| BG102043A (en) | Preparation of clavulanates | |
| IT8748221A0 (it) | Procedimento di preparazione di esteri di acidi carbossilici insaturi | |
| IT1271623B (it) | N-acilderivati di aminoalcoli con acidi monocarbossilici e bicarbossilici con attivita' neuroprotettiva nelle patologie neurologiche correlate ad eccitotossicita' | |
| NO942531L (no) | Fremgangsmåte for fremstilling av 3-acylöstratriener og acylbenzener | |
| FI935712L (fi) | Menetelmä optisesti aktiivisten transglysidihappoestereiden entsyaattiseksi valmistamiseksi | |
| SE8304331L (sv) | Lekemedel med analgetisk verkan | |
| IT8219064A0 (it) | Procedimento per fabbricare esteri di acidi non saturi. | |
| IT1197888B (it) | Procedimento per la preparazione di esteri carbossilici insaturi | |
| 土井秀平 | Synthetic studies from α, β-unsaturated α-nitroesters | |
| ES2174185T3 (es) | Procedimiento para la preparacion de halogenuros de (5,6-dicarboxi-3-piridil) metilamonio. | |
| IT8821430A0 (it) | Esteri dell'acido tiamorfolinone carbossilico e di suoi derivati, loro procedimento di preparazione e loro impiego nel settore cosmetico e nel settore dermo farmaceutico. | |
| IT8423885A1 (it) | Procedimento per la preparazione di esteri e/o sali di acidi alfa-beta insaturi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970418 |