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IT1256035B - IMMUNOSTIMULATING ACTIVITY GLUCANS - Google Patents

IMMUNOSTIMULATING ACTIVITY GLUCANS

Info

Publication number
IT1256035B
IT1256035B ITMI921967A ITMI921967A IT1256035B IT 1256035 B IT1256035 B IT 1256035B IT MI921967 A ITMI921967 A IT MI921967A IT MI921967 A ITMI921967 A IT MI921967A IT 1256035 B IT1256035 B IT 1256035B
Authority
IT
Italy
Prior art keywords
glucans
immunostimulating activity
activity
immunostimulating
bonds
Prior art date
Application number
ITMI921967A
Other languages
Italian (it)
Original Assignee
Consiglio Nazionale Ricerche
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche, Ist Superiore Sanita filed Critical Consiglio Nazionale Ricerche
Priority to ITMI921967A priority Critical patent/IT1256035B/en
Publication of ITMI921967A0 publication Critical patent/ITMI921967A0/en
Priority to PCT/EP1993/002063 priority patent/WO1994003500A1/en
Priority to AU47063/93A priority patent/AU4706393A/en
Priority to EP93917731A priority patent/EP0654047A1/en
Priority to MX9304793A priority patent/MX9304793A/en
Priority to ZA935730A priority patent/ZA935730B/en
Priority to CN93109362A priority patent/CN1082056A/en
Publication of ITMI921967A1 publication Critical patent/ITMI921967A1/en
Application granted granted Critical
Publication of IT1256035B publication Critical patent/IT1256035B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Si descrivono glucani estratti da cellule di lievito caratterizzati da rapporto tra legami ?(1-3) e ?(1-6) pari a circa 1 e da elevata attività immunostimolante.Glucans extracted from yeast cells characterized by a ratio between bonds? (1-3) and? (1-6) equal to about 1 and by high immunostimulating activity are described.

ITMI921967A 1992-08-10 1992-08-10 IMMUNOSTIMULATING ACTIVITY GLUCANS IT1256035B (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI921967A IT1256035B (en) 1992-08-10 1992-08-10 IMMUNOSTIMULATING ACTIVITY GLUCANS
PCT/EP1993/002063 WO1994003500A1 (en) 1992-08-10 1993-08-03 Glucans with immunostimulant activity
AU47063/93A AU4706393A (en) 1992-08-10 1993-08-03 Glucans with immunostimulant activity
EP93917731A EP0654047A1 (en) 1992-08-10 1993-08-03 Glucans with immunostimulant activity
MX9304793A MX9304793A (en) 1992-08-10 1993-08-06 GLICANS OF IMMUNO-STIMULATING ACTIVITY.
ZA935730A ZA935730B (en) 1992-08-10 1993-08-06 Glucans with immunostimulant activity.
CN93109362A CN1082056A (en) 1992-08-10 1993-08-06 Dextran with immunostimulatory activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921967A IT1256035B (en) 1992-08-10 1992-08-10 IMMUNOSTIMULATING ACTIVITY GLUCANS

Publications (3)

Publication Number Publication Date
ITMI921967A0 ITMI921967A0 (en) 1992-08-10
ITMI921967A1 ITMI921967A1 (en) 1994-02-10
IT1256035B true IT1256035B (en) 1995-11-21

Family

ID=11363857

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921967A IT1256035B (en) 1992-08-10 1992-08-10 IMMUNOSTIMULATING ACTIVITY GLUCANS

Country Status (7)

Country Link
EP (1) EP0654047A1 (en)
CN (1) CN1082056A (en)
AU (1) AU4706393A (en)
IT (1) IT1256035B (en)
MX (1) MX9304793A (en)
WO (1) WO1994003500A1 (en)
ZA (1) ZA935730B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650626B2 (en) * 1989-09-08 1994-06-30 Alpha-Beta Technology, Inc. Method for producing soluble glucans
US5488040A (en) * 1989-09-08 1996-01-30 Alpha-Beta Technology, Inc. Use of neutral soluble glucan preparations to stimulate platelet production
US5622939A (en) * 1992-08-21 1997-04-22 Alpha-Beta Technology, Inc. Glucan preparation
US5811542A (en) * 1989-09-08 1998-09-22 Alpha-Beta Technology, Inc. Method for producing soluble glucans
FR2728269A1 (en) * 1994-12-20 1996-06-21 Inst Francais Du Petrole PROCESS FOR TREATING A FERMENTATION MUST CONTAINING POLYSACCHARIDE
DE19629118C2 (en) * 1996-07-19 2001-11-29 Mibelle Ag Cosmetics Buchs Process for isolating glucan from yeast
US6046323A (en) * 1997-07-29 2000-04-04 The Collaborative Group, Ltd. Conformations of PPG-glucan
AU6261999A (en) 1998-09-25 2000-04-17 Collaborative Group, Ltd., The Very high molecular weight beta-glucans
US6369216B1 (en) 1998-09-25 2002-04-09 Biopolymer Engineering Pharmaceutical, Inc. Very high molecular weight β-glucans
WO2002012348A2 (en) 2000-08-03 2002-02-14 Abac R & D Gmbh Isolation of glucan particles and uses thereof
US7507724B2 (en) * 2001-01-16 2009-03-24 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
EP1545208A4 (en) 2002-08-13 2006-04-12 Biopolymer Engineering Inc Methods of using beta glucan as a radioprotective agent
CA2496508C (en) 2002-09-04 2014-04-22 University Of Louisville Research Foundation, Inc. Cancer therapy using beta glucan and antibodies
SK285346B6 (en) * 2004-01-14 2006-11-03 Pleuran, S. R. O. A method for preparing a fungal glucan hydrogel with antibacterial and immunostimulatory effects
CN101117356B (en) * 2007-09-17 2010-06-09 中国农业大学 A kind of preparation method of water-insoluble β-1,3/1,6-glucan
CN101885784B (en) * 2010-07-20 2012-08-08 三峡大学 Method for producing glucomannan by liquid culture of konjac cells
CN105907714A (en) * 2016-04-28 2016-08-31 王晓冰 Improved method for cultivating NK (natural killer) cells
US20200048608A1 (en) * 2018-08-13 2020-02-13 Lifenergy Biotech Corp. Method for in vitro activation of immune cells
EP4291241A1 (en) * 2021-02-14 2023-12-20 Universidade Católica Portuguesa - UCP Yeast glucans, methods and uses thereof
CN114376231B (en) * 2021-12-30 2024-07-09 汤臣倍健股份有限公司 Application of yeast-beta-glucan in preparation of medicines or health-care foods with immunity enhancing function

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992540A (en) * 1984-11-28 1991-02-12 Massachusetts Institute Of Technology Glucan composition and process for preparation thereof
IT1232310B (en) * 1989-09-04 1992-01-28 Consiglio Nazionale Ricerche PROCESS FOR THE PREPARATION OF A PRODUCT CONTAINING GLUCAN FROM CANDIDA ALBICANS BMM-12
AU650626B2 (en) * 1989-09-08 1994-06-30 Alpha-Beta Technology, Inc. Method for producing soluble glucans

Also Published As

Publication number Publication date
ITMI921967A0 (en) 1992-08-10
WO1994003500A1 (en) 1994-02-17
AU4706393A (en) 1994-03-03
ITMI921967A1 (en) 1994-02-10
MX9304793A (en) 1994-05-31
ZA935730B (en) 1994-03-03
CN1082056A (en) 1994-02-16
EP0654047A1 (en) 1995-05-24

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950830