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IT1251685B - Composizioni farmaceutiche contenenti una calcitonina - Google Patents

Composizioni farmaceutiche contenenti una calcitonina

Info

Publication number
IT1251685B
IT1251685B ITMI912703A ITMI912703A IT1251685B IT 1251685 B IT1251685 B IT 1251685B IT MI912703 A ITMI912703 A IT MI912703A IT MI912703 A ITMI912703 A IT MI912703A IT 1251685 B IT1251685 B IT 1251685B
Authority
IT
Italy
Prior art keywords
calcitonin
pharmaceutical compositions
compositions containing
glycyrrhizinate
absorption
Prior art date
Application number
ITMI912703A
Other languages
English (en)
Inventor
Laura Chiodini
Teodoro Fonio
Mario Pinza
Original Assignee
Isf Spa
Smithkline Beecham Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa, Smithkline Beecham Farma filed Critical Isf Spa
Publication of ITMI912703A0 publication Critical patent/ITMI912703A0/it
Priority to ITMI912703A priority Critical patent/IT1251685B/it
Priority to JP5506629A priority patent/JPH07500099A/ja
Priority to AU26834/92A priority patent/AU2683492A/en
Priority to BR9206707A priority patent/BR9206707A/pt
Priority to PCT/EP1992/002321 priority patent/WO1993006854A1/en
Priority to CA002120755A priority patent/CA2120755A1/en
Priority to EP92920956A priority patent/EP0607229A1/en
Priority to MX9205852A priority patent/MX9205852A/es
Priority to PT100946A priority patent/PT100946A/pt
Publication of ITMI912703A1 publication Critical patent/ITMI912703A1/it
Application granted granted Critical
Publication of IT1251685B publication Critical patent/IT1251685B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invenzione si riferisce a nuove composizioni farmaceutiche contenenti calcitonine e a nuovo metodo per migliorare l'assorbimento di una calcitonina attraverso una membrana mucosa.Le composizioni farmaceutiche comprendono una calcitonina, una quantità efficace di un promotore dell'assorbimento che è un glicirrizinato, una quantità efficace di alcool benzilico e un veicolo farmaceuticamente accettabile; preferibilmente il glicirrizinato è glicirrizinato d'ammonio.
ITMI912703A 1991-10-11 1991-10-11 Composizioni farmaceutiche contenenti una calcitonina IT1251685B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITMI912703A IT1251685B (it) 1991-10-11 1991-10-11 Composizioni farmaceutiche contenenti una calcitonina
PCT/EP1992/002321 WO1993006854A1 (en) 1991-10-11 1992-10-08 Pharmaceutical compositions comprising a calcitonin, a glycyrrhizinate as absorption enhancer and benzyl
AU26834/92A AU2683492A (en) 1991-10-11 1992-10-08 Pharmaceutical compositions comprising a calcitonin, a glycyrrhizinate as absorption enhancer and benzyl
BR9206707A BR9206707A (pt) 1991-10-11 1992-10-08 Compostos farmacêuticos contendo uma calcitonina
JP5506629A JPH07500099A (ja) 1991-10-11 1992-10-08 カルシトニン、吸収エンハンサーとしてのグリシルリジン酸塩およびベンジルからなる医薬組成物
CA002120755A CA2120755A1 (en) 1991-10-11 1992-10-08 Pharmaceutical compositions comprising a calcitonin, a glycyrrhizinate as absorption enhancer and benzyl
EP92920956A EP0607229A1 (en) 1991-10-11 1992-10-08 Pharmaceutical compositions comprising a calcitonin, a glycyrrhizinate as absorption enhancer and benzyl
MX9205852A MX9205852A (es) 1991-10-11 1992-10-09 Composiciones farmaceuticas que contienen una calcitonina
PT100946A PT100946A (pt) 1991-10-11 1992-10-09 Composicoes farmaceuticas contendo uma calcitonina e seu processo de preparacao

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912703A IT1251685B (it) 1991-10-11 1991-10-11 Composizioni farmaceutiche contenenti una calcitonina

Publications (3)

Publication Number Publication Date
ITMI912703A0 ITMI912703A0 (it) 1991-10-11
ITMI912703A1 ITMI912703A1 (it) 1993-04-11
IT1251685B true IT1251685B (it) 1995-05-19

Family

ID=11360856

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI912703A IT1251685B (it) 1991-10-11 1991-10-11 Composizioni farmaceutiche contenenti una calcitonina

Country Status (9)

Country Link
EP (1) EP0607229A1 (it)
JP (1) JPH07500099A (it)
AU (1) AU2683492A (it)
BR (1) BR9206707A (it)
CA (1) CA2120755A1 (it)
IT (1) IT1251685B (it)
MX (1) MX9205852A (it)
PT (1) PT100946A (it)
WO (1) WO1993006854A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2285921A (en) * 1994-01-31 1995-08-02 Leilani Lea Sublingual administration of medicaments
EP0726075A1 (en) * 1995-02-08 1996-08-14 Therapicon Srl Pharmaceutical non-inorganic saline solutions for endonasal administration
AU1808897A (en) * 1995-12-13 1997-07-03 Dullatur Limited A calcitonin preparation
IT1294191B1 (it) * 1997-09-05 1999-03-22 Alfa Wassermann Spa Composizioni farmaceutiche contenenti calcitonina in un dosatore spray per somministrazione intranasale.
GB2368792A (en) 2000-10-06 2002-05-15 Roger Randal Charles New Absorption enhancers
ITRM20010048A1 (it) * 2001-01-30 2002-07-30 Gregorio Mauro De Metodo per preparare soluzioni acquose fisiologicamente accettabili esoluzioni cosi' ottenute.
GB0308734D0 (en) 2003-04-15 2003-05-21 Axcess Ltd Uptake of macromolecules
GB0308732D0 (en) 2003-04-15 2003-05-21 Axcess Ltd Absorption enhancers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60188315A (ja) * 1984-03-07 1985-09-25 Yamanouchi Pharmaceut Co Ltd グリチルレチン酸配合鎮痒プラスター
JPS61267528A (ja) * 1984-11-26 1986-11-27 Yamanouchi Pharmaceut Co Ltd 吸収促進剤を含有するカルシトニン経鼻剤
ES2061688T3 (es) * 1987-11-13 1994-12-16 Smithkline Beecham Farma Composiciones farmaceuticas que comprenden una calcitonina y un glicirricinato como mejorador de la absorcion.
JPH078806B2 (ja) * 1990-08-16 1995-02-01 旭化成工業株式会社 カルシトニン類含有経鼻投与用乳剤

Also Published As

Publication number Publication date
CA2120755A1 (en) 1993-04-15
WO1993006854A1 (en) 1993-04-15
PT100946A (pt) 1993-10-29
MX9205852A (es) 1993-06-01
JPH07500099A (ja) 1995-01-05
ITMI912703A0 (it) 1991-10-11
AU2683492A (en) 1993-05-03
ITMI912703A1 (it) 1993-04-11
EP0607229A1 (en) 1994-07-27
BR9206707A (pt) 1995-10-31

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19951031