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IT1199339B - N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono - Google Patents

N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono

Info

Publication number
IT1199339B
IT1199339B IT48779/86A IT4877986A IT1199339B IT 1199339 B IT1199339 B IT 1199339B IT 48779/86 A IT48779/86 A IT 48779/86A IT 4877986 A IT4877986 A IT 4877986A IT 1199339 B IT1199339 B IT 1199339B
Authority
IT
Italy
Prior art keywords
amino
tetraline
derivatives
alchil
dimetoxy
Prior art date
Application number
IT48779/86A
Other languages
English (en)
Other versions
IT8648779A0 (it
Inventor
Mauro Marzi
Maria Ornella Tinti
Fabio Romano Di
Domenico Misiti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT48779/86A priority Critical patent/IT1199339B/it
Publication of IT8648779A0 publication Critical patent/IT8648779A0/it
Priority to ES198787830449T priority patent/ES2035105T3/es
Priority to AT87830449T priority patent/ATE80608T1/de
Priority to US07/135,335 priority patent/US5047433A/en
Priority to EP87830449A priority patent/EP0273017B1/en
Priority to DE8787830449T priority patent/DE3781783T2/de
Priority to JP62326631A priority patent/JP2545105B2/ja
Application granted granted Critical
Publication of IT1199339B publication Critical patent/IT1199339B/it
Priority to GR920402697T priority patent/GR3006342T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT48779/86A 1986-12-23 1986-12-23 N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono IT1199339B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT48779/86A IT1199339B (it) 1986-12-23 1986-12-23 N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono
ES198787830449T ES2035105T3 (es) 1986-12-23 1987-12-21 Procedimiento para la preparacion de n-alquil derivados de 2-amino-6,7-dimetoxi tetralina.
AT87830449T ATE80608T1 (de) 1986-12-23 1987-12-21 N-alkyl-derivate von 2-amino-6,7dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.
US07/135,335 US5047433A (en) 1986-12-23 1987-12-21 N-alkyl derivatives of 2-amino-6,7-dimethoxy tetraline and pharmaceutical compositions having antihypertensive activity containing same
EP87830449A EP0273017B1 (en) 1986-12-23 1987-12-21 N-alkyl derivatives of 2-amino-6,7-dimethoxy tetraline, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same
DE8787830449T DE3781783T2 (de) 1986-12-23 1987-12-21 N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.
JP62326631A JP2545105B2 (ja) 1986-12-23 1987-12-23 ２−アミノ−６，７−ジメトキシテトラリン−ｎ−アルキル誘導体
GR920402697T GR3006342T3 (it) 1986-12-23 1992-11-26

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48779/86A IT1199339B (it) 1986-12-23 1986-12-23 N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono

Publications (2)

Publication Number Publication Date
IT8648779A0 IT8648779A0 (it) 1986-12-23
IT1199339B true IT1199339B (it) 1988-12-30

Family

ID=11268513

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48779/86A IT1199339B (it) 1986-12-23 1986-12-23 N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono

Country Status (8)

Country Link
US (1) US5047433A (it)
EP (1) EP0273017B1 (it)
JP (1) JP2545105B2 (it)
AT (1) ATE80608T1 (it)
DE (1) DE3781783T2 (it)
ES (1) ES2035105T3 (it)
GR (1) GR3006342T3 (it)
IT (1) IT1199339B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230931B (it) * 1989-06-27 1991-11-08 Chiesi Farma Spa Derivati di 2 ammino 1,2,3,4 tetraidronaftalene ad attivita' cardiovascolare, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1241988B (it) * 1990-06-15 1994-02-02 Sigma Tau Ind Farmaceuti 2- amminotetraline-6, 7-sostituite attive come immunomodulanti e composizioni farmaceutiche che le contengono
IL104567A (en) * 1992-02-03 1997-03-18 Fujisawa Pharmaceutical Co Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IT1278045B1 (it) * 1995-03-09 1997-11-17 Sigma Tau Ind Farmaceuti Uso di 2-amminotetraline-6,7-sostituite per la preparazione di composizioni farmaceutiche atte al trattamento dello shock, e di

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709996A (en) * 1963-08-02 1973-01-09 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-aminoindane compounds and adapted for administration to obtain inhibition of monoamine oxidase enzyme and process
GB1187017A (en) * 1966-07-16 1970-04-08 Aspro Nicholas Ltd Substituted 1-Amino Indanes and Tetrahydronaphthalens
US3629463A (en) * 1969-04-15 1971-12-21 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-amino-1 2 3 4-tetrahydronaphthalenes and use of such n-cyclopropyl compounds as hypotensives
US3930022A (en) * 1972-07-03 1975-12-30 Squibb & Sons Inc Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia
US4181738A (en) * 1976-11-30 1980-01-01 Cornell Research Foundation, Inc. Catecholamine derivatives, a process for their preparation and pharmaceutical compositions thereof
US4314082A (en) * 1978-07-14 1982-02-02 American Hospital Supply Corporation Derivatives of 2-amino-6,7-dihydroxytetrahydro naphthalene (ADTN)
ATE6500T1 (de) * 1980-01-30 1984-03-15 American Hospital Supply Corporation 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3 4-tetrahydronaphthalin, seine salze, und verfahren zu dessen herstellung.
EP0168505B1 (en) * 1984-05-22 1989-08-09 Whitby Research Incorporated Substituted 2-aminotetralins and processes for synthesis
IL79323A (en) * 1985-07-10 1990-03-19 Sanofi Sa Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JP2545105B2 (ja) 1996-10-16
EP0273017B1 (en) 1992-09-16
EP0273017A2 (en) 1988-06-29
DE3781783D1 (de) 1992-10-22
ATE80608T1 (de) 1992-10-15
ES2035105T3 (es) 1993-04-16
EP0273017A3 (en) 1989-03-01
DE3781783T2 (de) 1993-02-25
US5047433A (en) 1991-09-10
IT8648779A0 (it) 1986-12-23
GR3006342T3 (it) 1993-06-21
JPS63190858A (ja) 1988-08-08

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971103