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IT1176711B - Derivati di acidi prostaglandinfenil carbossilici 7-ossabiciclo sostituiti - Google Patents

Derivati di acidi prostaglandinfenil carbossilici 7-ossabiciclo sostituiti

Info

Publication number
IT1176711B
IT1176711B IT22708/84A IT2270884A IT1176711B IT 1176711 B IT1176711 B IT 1176711B IT 22708/84 A IT22708/84 A IT 22708/84A IT 2270884 A IT2270884 A IT 2270884A IT 1176711 B IT1176711 B IT 1176711B
Authority
IT
Italy
Prior art keywords
prostaglandinphenyl
oxabyclic
carboxyl
acid derivatives
derivatives replaced
Prior art date
Application number
IT22708/84A
Other languages
English (en)
Other versions
IT8422708A1 (it
IT8422708A0 (it
Inventor
Das Jagabandhu
Martin F Haslanger
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8422708A0 publication Critical patent/IT8422708A0/it
Publication of IT8422708A1 publication Critical patent/IT8422708A1/it
Application granted granted Critical
Publication of IT1176711B publication Critical patent/IT1176711B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT22708/84A 1983-09-19 1984-09-18 Derivati di acidi prostaglandinfenil carbossilici 7-ossabiciclo sostituiti IT1176711B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/533,461 US4474804A (en) 1983-09-19 1983-09-19 7-Oxabicyclo substituted prostaglandin phenyl carboxylic acid derivatives useful as cardiovascular agents

Publications (3)

Publication Number Publication Date
IT8422708A0 IT8422708A0 (it) 1984-09-18
IT8422708A1 IT8422708A1 (it) 1986-03-18
IT1176711B true IT1176711B (it) 1987-08-18

Family

ID=24126048

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22708/84A IT1176711B (it) 1983-09-19 1984-09-18 Derivati di acidi prostaglandinfenil carbossilici 7-ossabiciclo sostituiti

Country Status (6)

Country Link
US (1) US4474804A (it)
JP (1) JPS6087278A (it)
DE (1) DE3434245A1 (it)
FR (1) FR2553773A1 (it)
GB (1) GB2146640A (it)
IT (1) IT1176711B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4658033A (en) * 1985-09-23 1987-04-14 Iowa State University Research Foundation, Inc. Synthesis of interphenylene prostaglandin analogs
US4883811A (en) * 1988-11-17 1989-11-28 Misra Raj N 7-Oxabicycloheptane imino interphenylene substituted prostaglandin analogs useful in the treatment of thrombotic disease
US4883809A (en) * 1988-11-17 1989-11-28 Misra Raj N 7-Oxabicycloheptane imino interphenyleneoxy substituted prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5100889A (en) * 1989-04-03 1992-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5153327A (en) * 1988-12-23 1992-10-06 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US4977174A (en) * 1989-06-12 1990-12-11 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5126370A (en) * 1990-12-24 1992-06-30 E. R. Squibb & Sons, Inc. Anti-thrombotic heterocyclic amido prostaglandin analogs
US5135939A (en) * 1991-01-28 1992-08-04 E. R. Squibb & Sons, Inc. Heterocyclic ketone prostaglandin analogs
US5158967A (en) * 1991-06-12 1992-10-27 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4368332A (en) * 1979-01-05 1983-01-11 National Research Development Corporation Prostaglandins
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
IL65387A0 (en) * 1981-04-14 1982-05-31 Chinoin Gyogyszer Es Vegyeszet 2,3,4-trinor-m-inter-phenylene-prostaglandin derivatives and a process for the preparation thereof

Also Published As

Publication number Publication date
GB8423460D0 (en) 1984-10-24
FR2553773A1 (fr) 1985-04-26
DE3434245A1 (de) 1985-04-04
US4474804A (en) 1984-10-02
GB2146640A (en) 1985-04-24
JPS6087278A (ja) 1985-05-16
IT8422708A1 (it) 1986-03-18
IT8422708A0 (it) 1984-09-18

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