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IT1172073B - PROCEDURE FOR THE PREPARATION OF BUSPIRONE - Google Patents

PROCEDURE FOR THE PREPARATION OF BUSPIRONE

Info

Publication number
IT1172073B
IT1172073B IT49718/81A IT4971881A IT1172073B IT 1172073 B IT1172073 B IT 1172073B IT 49718/81 A IT49718/81 A IT 49718/81A IT 4971881 A IT4971881 A IT 4971881A IT 1172073 B IT1172073 B IT 1172073B
Authority
IT
Italy
Prior art keywords
buspirone
procedure
preparation
Prior art date
Application number
IT49718/81A
Other languages
Italian (it)
Other versions
IT8149718A0 (en
Inventor
Robert R Covington
Davis L Temple Jr
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8149718A0 publication Critical patent/IT8149718A0/en
Application granted granted Critical
Publication of IT1172073B publication Critical patent/IT1172073B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT49718/81A 1980-12-11 1981-11-16 PROCEDURE FOR THE PREPARATION OF BUSPIRONE IT1172073B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21521480A 1980-12-11 1980-12-11

Publications (2)

Publication Number Publication Date
IT8149718A0 IT8149718A0 (en) 1981-11-16
IT1172073B true IT1172073B (en) 1987-06-18

Family

ID=22802113

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49718/81A IT1172073B (en) 1980-12-11 1981-11-16 PROCEDURE FOR THE PREPARATION OF BUSPIRONE

Country Status (18)

Country Link
JP (1) JPS57122082A (en)
AT (1) AT380686B (en)
AU (1) AU528067B2 (en)
BE (1) BE891446A (en)
CA (1) CA1172255A (en)
CH (1) CH647518A5 (en)
DE (1) DE3149011A1 (en)
DK (1) DK154560C (en)
FI (1) FI73993C (en)
FR (1) FR2496105B1 (en)
GB (1) GB2089341B (en)
GR (1) GR76331B (en)
IE (1) IE51948B1 (en)
IT (1) IT1172073B (en)
LU (1) LU83833A1 (en)
NL (1) NL8105529A (en)
SE (1) SE444438B (en)
YU (1) YU42432B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212301B (en) * 1989-04-28 1996-05-28 Alkaloida Vegyeszeti Gyar Process for producing buspirone
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
KR950014099A (en) * 1993-11-10 1995-06-15 장기하 Method for preparing N- (2-pyrimidyl) piperazinyl butylamide
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (en) * 1969-11-24 1971-05-24 Bristol Myers Co HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION
DE2341925A1 (en) * 1973-08-20 1975-03-06 Thomae Gmbh Dr K 2,4, (opt.5-), 6-substd. pyriminidines as antithrombic agents - e.g. 6-methyl-5-nitro-2-piperazino-4-thiomorpolino-pyrimidine

Also Published As

Publication number Publication date
FI73993B (en) 1987-08-31
DK154560B (en) 1988-11-28
YU243681A (en) 1984-02-29
JPH0113476B2 (en) 1989-03-06
AU528067B2 (en) 1983-04-14
YU42432B (en) 1988-08-31
BE891446A (en) 1982-06-11
FR2496105B1 (en) 1985-12-13
IT8149718A0 (en) 1981-11-16
CA1172255A (en) 1984-08-07
FI73993C (en) 1987-12-10
DE3149011A1 (en) 1982-07-15
GB2089341A (en) 1982-06-23
GR76331B (en) 1984-08-04
LU83833A1 (en) 1982-07-07
SE8107446L (en) 1982-06-12
NL8105529A (en) 1982-07-01
FR2496105A1 (en) 1982-06-18
IE51948B1 (en) 1987-04-29
ATA529581A (en) 1985-11-15
FI813937L (en) 1982-06-12
CH647518A5 (en) 1985-01-31
IE812897L (en) 1982-06-11
DE3149011C2 (en) 1988-08-25
DK154560C (en) 1989-04-17
AU7604181A (en) 1982-07-15
AT380686B (en) 1986-06-25
SE444438B (en) 1986-04-14
GB2089341B (en) 1984-09-19
DK548081A (en) 1982-06-12
JPS57122082A (en) 1982-07-29

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971129