IT1150682B - PROCEDURE FOR THE PRODUCTION OF SUBSTANCES PRODUCED FROM CELLS, PARTICULARLY OF ANTIBODIES AND SIMILAR - Google Patents

PROCEDURE FOR THE PRODUCTION OF SUBSTANCES PRODUCED FROM CELLS, PARTICULARLY OF ANTIBODIES AND SIMILAR

Info

Publication number: IT1150682B
Authority: IT; Italy
Prior art keywords: antibodies; cells; procedure; production; similar
Prior art date: 1981-03-13

Application number

IT20140/82A

Other languages

Italian (it)

Other versions

IT8220140A0 (en

Inventor

Franklin Lim

Original Assignee

Damon Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-13

Filing date

1982-03-12

Publication date

1986-12-17

1982-03-12 Application filed by Damon Corp filed Critical Damon Corp

1982-03-12 Publication of IT8220140A0 publication Critical patent/IT8220140A0/en

1986-12-17 Application granted granted Critical

1986-12-17 Publication of IT1150682B publication Critical patent/IT1150682B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
- A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/32—Polylysine, polyornithine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Veterinary Medicine (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

IT20140/82A 1981-03-13 1982-03-12 PROCEDURE FOR THE PRODUCTION OF SUBSTANCES PRODUCED FROM CELLS, PARTICULARLY OF ANTIBODIES AND SIMILAR IT1150682B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US24358381A	1981-03-13	1981-03-13

Publications (2)

Publication Number	Publication Date
IT8220140A0 IT8220140A0 (en)	1982-03-12
IT1150682B true IT1150682B (en)	1986-12-17

Family

ID=22919321

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT20140/82A IT1150682B (en)	1981-03-13	1982-03-12	PROCEDURE FOR THE PRODUCTION OF SUBSTANCES PRODUCED FROM CELLS, PARTICULARLY OF ANTIBODIES AND SIMILAR

Country Status (11)

Country	Link
JP (2)	JPS5816693A (en)
BE (1)	BE892479A (en)
CA (1)	CA1172961A (en)
CH (1)	CH654328A5 (en)
DE (1)	DE3209127A1 (en)
DK (1)	DK112282A (en)
FR (1)	FR2503183B1 (en)
GB (1)	GB2094833B (en)
IT (1)	IT1150682B (en)
NO (1)	NO163060C (en)
SE (1)	SE454780B (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO161446C (en) *	1981-03-13	1989-08-16	Damon Biotech Inc	PROCEDURE FOR CULTING CELLS RELATED TO ANCHORING.
US4582799A (en) *	1983-04-15	1986-04-15	Damon Biotech, Inc.	Process for recovering nonsecreted substances produced by cells
CA1196862A (en) *	1983-06-01	1985-11-19	Anthony M.F. Sun	Microencapsulation of living tissue and cells
JPS6025929A (en) *	1983-07-20	1985-02-08	ザ・スト−ル・リサ−チ・アンド・デイベロツプメント・コ−ポレ−シヨン	Encapsulated cell, manufacture and use
JPS60141281A (en) *	1983-12-28	1985-07-26	Meiji Milk Prod Co Ltd	Method and device for producing bacterial granules
EP0152898B1 (en) *	1984-02-15	1990-01-17	Massachusetts Institute Of Technology	Process for encapsulation and encapsulated active material system(
JPS60175539A (en) *	1984-02-23	1985-09-09	Snow Brand Milk Prod Co Ltd	Capsule and its production
US5672347A (en) *	1984-07-05	1997-09-30	Genentech, Inc.	Tumor necrosis factor antagonists and their use
US6686455B1 (en)	1984-07-05	2004-02-03	Genentech, Inc.	Tumor necrosis factor
GR851626B (en) *	1984-07-05	1985-11-26	Genentech Inc
CA1241598A (en) *	1984-07-11	1988-09-06	Connaught Laboratories Limited	Droplet generation
EP0199362A3 (en) *	1985-04-26	1987-10-07	Massachusetts Institute Of Technology	System and apparatus for delayed and pulsed release of biologically active substances
CA1265443A (en) *	1985-09-18	1990-02-06	Elieser Gorelik	Assays for chemotherapeutic agents
DE3534983A1 (en) *	1985-10-01	1987-04-02	Sturge John & E Ltd	COMPLEX IMMOBILIZED BIOCATALYSTS AND THEIR PRODUCTION AND USE
JPS62166891A (en) *	1986-01-20	1987-07-23	Snow Brand Milk Prod Co Ltd	Production of useful substance by cell cultivation
WO1987004367A1 (en) *	1986-01-23	1987-07-30	Ltl Associates	Covalent membranes
DE3615043A1 (en) *	1986-05-03	1987-11-05	Hoechst Ag	METHOD FOR ENCODING BIOLOGICALLY ACTIVE MATERIAL
IL79052A0 (en) *	1986-06-06	1986-11-30	Univ Ramot	Device and process for production of alginate-shell beads containing biologically active material
JP2530690Y2 (en) *	1986-08-28	1997-03-26	カシオ計算機株式会社	Electronic musical instrument
US5010010A (en) *	1986-10-22	1991-04-23	Selmer-Sande, A.S.	Production of human parathyroid hormone from microorganisms
US5420242A (en) *	1986-10-22	1995-05-30	Kaare M. Gautvik	Production of human parathyroid hormone from microorganisms
AU627147B2 (en)	1986-10-22	1992-08-20	Peter Alestrom	Production of human parathyroid hormone from microorganisms
AU614747B2 (en) *	1987-04-22	1991-09-12	Michael Bay	Cell culture of anchorage dependent cells, materials and products
JPS6414225U (en) *	1987-07-15	1989-01-25
JPH025797U (en) *	1988-06-23	1990-01-16
WO1991010470A1 (en) *	1990-01-08	1991-07-25	Brown University Research Foundation	Devices and methods for enhanced delivery of active factors
US5800829A (en) *	1991-04-25	1998-09-01	Brown University Research Foundation	Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
EP0585368B1 (en) *	1991-04-25	1997-08-06	Brown University Research Foundation	Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
DE4229526B4 (en) *	1992-09-07	2006-02-16	Schrezenmeir, Jürgen, Dr.	Device for receiving and introducing biologically active tissues or cells into the human body
ES2178654T3 (en) *	1993-08-12	2003-01-01	Neurotech Sa	IMMONO-ISOLATED BIOCOMPATIBLE CAPSULES CONTAINING GENETICALLY ALTERED CELLS FOR THE SUPPLY OF BIOLOGICALLY ACTIVE MOLECULES.
US5908623A (en)	1993-08-12	1999-06-01	Cytotherapeutics, Inc.	Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5550050A (en) *	1994-04-15	1996-08-27	Cytotherapeutics, Inc.	Method for implanting encapsulated cells in a host
DE4426396A1 (en) *	1994-07-26	1996-02-01	Ulrich Prof Dr Zimmermann	Process for the preparation of concentrated solutions of microencapsulated cells or of suspended active substances in microencapsulated form
US5916790A (en) *	1995-03-03	1999-06-29	Metabolex, Inc.	Encapsulation compositions, and methods
SE9702401D0 (en)	1997-06-19	1997-06-19	Astra Ab	Pharmaceutical use
EP3156480B1 (en) *	2011-02-07	2020-03-25	Life Technologies Corporation	Compositions and methods for stabilizing susceptible compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4324683A (en) *	1975-08-20	1982-04-13	Damon Corporation	Encapsulation of labile biological material
US4352883A (en) *	1979-03-28	1982-10-05	Damon Corporation	Encapsulation of biological material
NO161446C (en) *	1981-03-13	1989-08-16	Damon Biotech Inc	PROCEDURE FOR CULTING CELLS RELATED TO ANCHORING.
NO158284C (en) *	1981-03-13	1988-08-17	Damon Biotech Inc	PROCEDURE FOR SELECTIVE USE OF A PERMEABLE MEMBRANE.

1982
- 1982-03-11 NO NO820794A patent/NO163060C/en unknown
- 1982-03-12 CH CH1575/82A patent/CH654328A5/en not_active IP Right Cessation
- 1982-03-12 CA CA000398218A patent/CA1172961A/en not_active Expired
- 1982-03-12 DK DK112282A patent/DK112282A/en not_active Application Discontinuation
- 1982-03-12 SE SE8201554A patent/SE454780B/en not_active IP Right Cessation
- 1982-03-12 FR FR8204242A patent/FR2503183B1/en not_active Expired
- 1982-03-12 JP JP57038238A patent/JPS5816693A/en active Granted
- 1982-03-12 BE BE0/207559A patent/BE892479A/en not_active IP Right Cessation
- 1982-03-12 GB GB8207309A patent/GB2094833B/en not_active Expired
- 1982-03-12 IT IT20140/82A patent/IT1150682B/en active
- 1982-03-12 DE DE19823209127 patent/DE3209127A1/en active Granted
1985
- 1985-08-22 JP JP60184995A patent/JPS6188893A/en active Granted

Also Published As

Publication number	Publication date
BE892479A (en)	1982-07-01
GB2094833B (en)	1984-06-20
DE3209127A1 (en)	1982-12-09
JPS6157288B2 (en)	1986-12-06
FR2503183B1 (en)	1985-11-08
JPS6244919B2 (en)	1987-09-24
NO163060B (en)	1989-12-18
GB2094833A (en)	1982-09-22
JPS6188893A (en)	1986-05-07
SE454780B (en)	1988-05-30
DK112282A (en)	1982-09-14
FR2503183A1 (en)	1982-10-08
SE8201554L (en)	1982-09-14
NO163060C (en)	1990-03-28
IT8220140A0 (en)	1982-03-12
JPS5816693A (en)	1983-01-31
CA1172961A (en)	1984-08-21
DE3209127C2 (en)	1988-02-04
CH654328A5 (en)	1986-02-14
NO820794L (en)	1982-09-14

Publication	Publication Date	Title
IT1150682B (en)	1986-12-17	PROCEDURE FOR THE PRODUCTION OF SUBSTANCES PRODUCED FROM CELLS, PARTICULARLY OF ANTIBODIES AND SIMILAR
IT8319234A0 (en)	1983-01-21	PROCEDURE FOR THE PRODUCTION OF HUMAN MONOCLONAL ANTIBODIES.
IT8119659A0 (en)	1981-02-11	COMPOSITE ARTICLE OF POLYTETRAFLUOROETHYLENE AND PROCEDURE FOR ITS MANUFACTURE.
IT1210939B (en)	1989-09-29	PROCEDURE FOR THE PRODUCTION OF RANGE-DECALACTON.
IT8323148A0 (en)	1983-10-05	METHOD FOR THE PRODUCTION OF AN IMMOBILIZED ENZYME PREPARATION.
IT1152146B (en)	1986-12-31	PROCEDURE FOR THE PRODUCTION OF NEROFUMO
IT8123284A0 (en)	1981-07-31	GAS. PROCEDURE FOR THE PRODUCTION OF
IT7824577A0 (en)	1978-06-14	METHOD FOR THE PRODUCTION OF ANTIBODIES.
NO870770L (en)	1987-08-27	PROCEDURE FOR THE MANUFACTURE OF MONOCLONAL ANTIBODIES.
IT8421885A0 (en)	1984-07-13	PROCEDURE FOR THE PRODUCTION OF ALCOHOL.
IT1154275B (en)	1987-01-21	PROCEDURE FOR THE PRODUCTION OF TIURAME DISULFURS
FI822408A7 (en)	1983-01-09	Method for the preparation of amidobenzamides.
IT1147923B (en)	1986-11-26	PROCEDURE FOR THE PRODUCTION OF DITIAZOLIL-2 (2.2 ') - DISULFURI
IT1141994B (en)	1986-10-08	PROCEDURE FOR THE PRODUCTION OF FRUCTOSIL ENZYME TRANSFERASE
IT1172243B (en)	1987-06-18	PROCEDURE FOR THE PRODUCTION OF L PROLINA FOR FERMENTATION
IT1214374B (en)	1990-01-18	DIGESTORE FOR THE FERMENTATION OF CELLULOSE MATERIALS AND THE PRODUCTION OF METHANE
IT8267822A0 (en)	1982-06-29	PROCEDURE FOR THE PREPARATION OF N.SUBSTITUTED ACRYL AND METHAACRYLAmides
RO82395A (en)	1983-08-03	PROCESS FOR THE PREPARATION OF ALFA-BETA-NESATURATI
FI852437L (en)	1985-12-23	ANORDINATION FOR THE FRAMEWORK OF TOMOGRAFIROENTGENBILDER.
FI813799A7 (en)	1982-05-29	Continuous process for the preparation of chloroalkylsulfonyl isocyanates.
IT8125157A0 (en)	1981-11-18	PROCEDURE FOR THE PREPARATION OF 2-AMINOETHANOLS.
FI855071A7 (en)	1986-06-20	Method for the preparation of monohalohydroquinones.
IT8222986A0 (en)	1982-08-26	PROCESS FOR THE PRODUCTION OF 2-AMINO-4-HYDROXY-5-HALOGEN-PYRIMI DINE.
IT8223188A0 (en)	1982-09-09	PROCEDURE FOR THE PRODUCTION OF SPHINGOMYELINASE.
IT8124426A0 (en)	1981-10-09	PROCEDURE FOR THE PRODUCTION OF ANTI-REFLECTIVE POLYCARBONATE SHEETS AND SHEETS OBTAINED THROUGH THIS PROCEDURE.

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970826