IT1148189B - 1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengono - Google Patents
1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengonoInfo
- Publication number
- IT1148189B IT1148189B IT48712/82A IT4871282A IT1148189B IT 1148189 B IT1148189 B IT 1148189B IT 48712/82 A IT48712/82 A IT 48712/82A IT 4871282 A IT4871282 A IT 4871282A IT 1148189 B IT1148189 B IT 1148189B
- Authority
- IT
- Italy
- Prior art keywords
- propan
- salts
- isopropossietossimetil
- isopropilamino
- fenossi
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- VHYCDWMUTMEGQY-UHFFFAOYSA-N bisoprolol Chemical compound CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1 VHYCDWMUTMEGQY-UHFFFAOYSA-N 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/305—Mercury compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813125636 DE3125636A1 (de) | 1981-06-30 | 1981-06-30 | 1-(p-2-isopropoxyethoxymethyl-phenoxy)-3-isopropylamino-propan-2-ol zur senkung des augeninnendrucks und ophtalmikum, enthalten diese verbindung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8248712A0 IT8248712A0 (it) | 1982-06-28 |
| IT1148189B true IT1148189B (it) | 1986-11-26 |
Family
ID=6135697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48712/82A IT1148189B (it) | 1981-06-30 | 1982-06-28 | 1-(p-2-isopropossietossimetil-fenossi)-3-isopropilammino-propan-2-olo e suoi sali per l'abbassamento della pressione endooculare e preparati oftalmici che li contengono |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4522829A (it) |
| EP (1) | EP0068160B1 (it) |
| JP (1) | JPS588047A (it) |
| AT (1) | ATE23112T1 (it) |
| BE (1) | BE893637A (it) |
| DE (2) | DE3125636A1 (it) |
| IT (1) | IT1148189B (it) |
| ZA (1) | ZA824599B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3151201A1 (de) * | 1981-12-23 | 1983-07-28 | Beiersdorf Ag, 2000 Hamburg | Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte |
| IT1163107B (it) * | 1983-02-15 | 1987-04-08 | Simes | Composizioni farmaceutiche e loro uso nel trattamento del glaucoma |
| ES2011255B3 (es) * | 1985-12-24 | 1990-01-01 | Merck & Co Inc | Bloqueadores beta selectivos para los ojos. |
| US4945182A (en) * | 1985-12-24 | 1990-07-31 | Merck & Co., Inc. | Oculoselective beta-blockers |
| US4694022A (en) * | 1986-12-24 | 1987-09-15 | Alcon Laboratories, Inc. | Fatty acid salts of betaxolol useful in the treatment of glaucoma |
| US5660851A (en) * | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts |
| AU2009202969B1 (en) * | 2009-07-23 | 2009-11-19 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| US7842714B2 (en) * | 2008-03-03 | 2010-11-30 | Allergan, Inc. | Ketorolac tromethamine compositions for treating ocular pain |
| US9192571B2 (en) | 2008-03-03 | 2015-11-24 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE384853B (sv) * | 1972-04-04 | 1976-05-24 | Haessle Ab | Forfarande for framstellning av nya aminer |
| FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| JPS52154528A (en) * | 1976-05-31 | 1977-12-22 | Kaken Pharmaceut Co Ltd | Remedy for glaucoma |
| DE2645710C2 (de) * | 1976-10-09 | 1985-06-27 | Merck Patent Gmbh, 6100 Darmstadt | Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung |
-
1981
- 1981-06-30 DE DE19813125636 patent/DE3125636A1/de not_active Withdrawn
-
1982
- 1982-05-29 DE DE8282104748T patent/DE3273950D1/de not_active Expired
- 1982-05-29 AT AT82104748T patent/ATE23112T1/de not_active IP Right Cessation
- 1982-05-29 EP EP82104748A patent/EP0068160B1/de not_active Expired
- 1982-06-24 BE BE0/208438A patent/BE893637A/fr not_active IP Right Cessation
- 1982-06-28 IT IT48712/82A patent/IT1148189B/it active
- 1982-06-28 ZA ZA824599A patent/ZA824599B/xx unknown
- 1982-06-30 JP JP57111858A patent/JPS588047A/ja active Pending
- 1982-06-30 US US06/393,914 patent/US4522829A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3125636A1 (de) | 1983-01-13 |
| DE3273950D1 (en) | 1986-12-04 |
| EP0068160B1 (de) | 1986-10-29 |
| IT8248712A0 (it) | 1982-06-28 |
| US4522829A (en) | 1985-06-11 |
| EP0068160A1 (de) | 1983-01-05 |
| ATE23112T1 (de) | 1986-11-15 |
| BE893637A (fr) | 1982-12-27 |
| JPS588047A (ja) | 1983-01-18 |
| ZA824599B (en) | 1983-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970628 |