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IS6766A - Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það - Google Patents

Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það

Info

Publication number
IS6766A
IS6766A IS6766A IS6766A IS6766A IS 6766 A IS6766 A IS 6766A IS 6766 A IS6766 A IS 6766A IS 6766 A IS6766 A IS 6766A IS 6766 A IS6766 A IS 6766A
Authority
IS
Iceland
Prior art keywords
pravastatin
epi
lactone
mixtures containing
largely free
Prior art date
Application number
IS6766A
Other languages
English (en)
Inventor
Keri Vilmos
Deak Lajos
Forgacs Ilona
Szabo Csaba
Edit Nagyne Arvai
Original Assignee
Teva Gyogyszergy βr Részvényt βrsas βg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22897222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS6766(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Gyogyszergy βr Részvényt βrsas βg filed Critical Teva Gyogyszergy βr Részvényt βrsas βg
Publication of IS6766A publication Critical patent/IS6766A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04Sodium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/52Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS6766A 2000-10-05 2003-04-01 Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það IS6766A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23827800P 2000-10-05 2000-10-05
PCT/US2001/031230 WO2002030415A1 (en) 2000-10-05 2001-10-05 Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same

Publications (1)

Publication Number Publication Date
IS6766A true IS6766A (is) 2003-04-01

Family

ID=22897222

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6766A IS6766A (is) 2000-10-05 2003-04-01 Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það

Country Status (18)

Country Link
EP (1) EP1330245A4 (is)
JP (6) JP3737801B2 (is)
KR (1) KR20030059173A (is)
CN (1) CN1468098A (is)
AU (1) AU2002211462A1 (is)
CA (1) CA2422744A1 (is)
CZ (1) CZ20031166A3 (is)
HR (1) HRP20030347A2 (is)
HU (1) HUP0400913A2 (is)
IL (1) IL155194A0 (is)
IS (1) IS6766A (is)
MX (1) MXPA03002963A (is)
NO (1) NO20031532D0 (is)
NZ (1) NZ525631A (is)
PL (1) PL361230A1 (is)
SK (1) SK5232003A3 (is)
WO (1) WO2002030415A1 (is)
ZA (1) ZA200302313B (is)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1265604T1 (sl) * 1999-11-30 2007-04-30 Sag Teva Gyogyszergyar Zartkoe Postopek za ponovno pridobivanje statinskih spojin iz fermentacije brozge
HUP0204012A3 (en) * 1999-11-30 2003-12-29 Biogal Gyogyszergyar Process for recovering statin compounds from a fermentation broth
EP1798214A3 (en) * 1999-11-30 2007-08-01 Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság Process for recovering statin compounds from a fermentation broth
WO2001043723A1 (en) 1999-12-14 2001-06-21 Biogal Gyogyszergyar Rt. Novel forms of pravastatin sodium
KR20030059173A (ko) * 2000-10-05 2003-07-07 비오갈 기오기스제르갸르 알티. 프라바스타틴 락톤과 에피-프라바스타틴을 실질적으로함유하지 않는 프라바스타틴 나트륨, 및 이를 포함하는조성물
JP3236282B1 (ja) * 2000-10-16 2001-12-10 三共株式会社 プラバスタチンを精製する方法
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
PL1641447T3 (pl) * 2003-11-24 2009-04-30 Teva Gyogyszergyar Zartkoerueen Muekoedoe Reszvenytarsasag Sposób oczyszczania prawastatyny
MX2007001553A (es) 2004-08-06 2008-03-07 Transform Pharmaceuticals Inc Nuevas composiciones farmaceuticas de estatina y metodos de tratamiento relacionados.
ES2254028B1 (es) * 2004-11-29 2007-03-01 Ercros Industrial, S.A. Procedimiento para la obtencion de pravastatina sodica purificada.
EP1851223A1 (en) * 2005-02-25 2007-11-07 Teva Pharmaceutical Industries Ltd Process of purifying tadalafil
JP4813841B2 (ja) * 2005-07-25 2011-11-09 キユーピー株式会社 プラバスタチンナトリウムの製造方法
HU229260B1 (en) * 2010-11-29 2013-10-28 Egis Gyogyszergyar Nyrt Process for preparation of rosuvastatin salts
CN114031496B (zh) * 2021-11-30 2024-09-27 广东蓝宝制药有限公司 一种高纯度普伐他汀1,1,3,3-四甲基丁胺的制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3378441A (en) * 1963-10-17 1968-04-16 S B Penick & Company Tetraene antibiotic purification
JPS5221594B2 (is) * 1973-09-29 1977-06-11
DE2604697A1 (de) * 1975-02-07 1976-08-19 Glaxo Lab Ltd Antibiotika
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
DK149080C (da) * 1980-06-06 1986-07-28 Sankyo Co Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
JPS572240A (en) * 1980-06-06 1982-01-07 Sankyo Co Ltd Ml-236b derivative
JPS5889191A (ja) * 1981-11-20 1983-05-27 Sankyo Co Ltd 3−ヒドロキシ−ml−236b誘導体の製造法
JPS5890509A (ja) * 1981-11-25 1983-05-30 Sankyo Co Ltd 高コレステロ−ル血症治療用組成物
JPH01190661A (ja) * 1988-01-22 1989-07-31 Konishi Kagaku Kogyo Kk 4,4′−ジヒドロキシジフエニルスルホンの精製法
JP2739328B2 (ja) * 1988-09-14 1998-04-15 日本ケミファ株式会社 ベンズイミダゾール化合物の精製方法
US5202029A (en) * 1991-03-13 1993-04-13 Caron Kabushiki Kaisha Process for purification of hmg-coa reductase inhibitors
NZ250609A (en) * 1992-12-28 1995-07-26 Sankyo Co Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
JPH06256278A (ja) * 1993-03-03 1994-09-13 Nissan Chem Ind Ltd 光学活性α−カルバモイルアルカン酸誘導体およびその製法
CA2126365C (en) * 1993-07-06 1999-08-24 Steven W. Felman Recovery of citric acid from impure process streams by addition of strong acids and salts thereof
JP2750222B2 (ja) * 1994-03-31 1998-05-13 ファイザー・インコーポレーテッド ナタマイシン回収方法
SI0784605T1 (en) * 1995-08-03 2000-08-31 Dsm N.V. Selective process for the deacylation of acylated compounds
JPH09124655A (ja) * 1995-11-01 1997-05-13 Sankyo Co Ltd 新規スクアレンシンターゼ阻害活性化合物
EP0877089A1 (en) * 1997-05-07 1998-11-11 Gist-Brocades B.V. HMG-CoA reductase inhibitor preparation process
SI20072A (sl) * 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze
SI20070A (sl) * 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Nove soli inhibitorjev HMG-CoA reduktaze
JP2000229855A (ja) * 1998-12-07 2000-08-22 Satoshi Takebe プラバスタチンナトリウム錠
CZ20012761A3 (cs) * 1999-02-03 2002-05-15 Institute For Drug Research Ltd. Mikrobiální způsob výroby pravastatinu
HUP9902352A1 (hu) * 1999-07-12 2000-09-28 Gyógyszerkutató Intézet Kft. Eljárás pravasztatin mikrobiológiai előállítására
HUP0204012A3 (en) * 1999-11-30 2003-12-29 Biogal Gyogyszergyar Process for recovering statin compounds from a fermentation broth
KR20030059173A (ko) * 2000-10-05 2003-07-07 비오갈 기오기스제르갸르 알티. 프라바스타틴 락톤과 에피-프라바스타틴을 실질적으로함유하지 않는 프라바스타틴 나트륨, 및 이를 포함하는조성물

Also Published As

Publication number Publication date
AU2002211462A1 (en) 2002-04-22
JP2009268479A (ja) 2009-11-19
JP2015212300A (ja) 2015-11-26
MXPA03002963A (es) 2005-01-25
CZ20031166A3 (cs) 2004-04-14
PL361230A1 (en) 2004-10-04
NO20031532L (no) 2003-04-04
JP2004510817A (ja) 2004-04-08
HUP0400913A2 (en) 2006-11-28
WO2002030415A1 (en) 2002-04-18
EP1330245A1 (en) 2003-07-30
JP2005013238A (ja) 2005-01-20
NO20031532D0 (no) 2003-04-04
ZA200302313B (en) 2004-03-25
JP2006036781A (ja) 2006-02-09
SK5232003A3 (en) 2004-06-08
HRP20030347A2 (en) 2005-04-30
JP3737801B2 (ja) 2006-01-25
EP1330245A4 (en) 2004-10-20
WO2002030415A9 (en) 2002-10-31
JP2013128486A (ja) 2013-07-04
KR20030059173A (ko) 2003-07-07
NZ525631A (en) 2005-05-27
IL155194A0 (en) 2003-11-23
CA2422744A1 (en) 2002-04-18
CN1468098A (zh) 2004-01-14

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