IS5193A - Ferli til að smíða fosfódíestera - Google Patents

Ferli til að smíða fosfódíestera

Info

Publication number: IS5193A
Authority: IS; Iceland
Prior art keywords: phosphodiester; alcohol; reaction; making process; phosphorodichlorodite
Prior art date: 1997-04-11

Application number

IS5193A

Other languages

English (en)

Other versions

IS1994B (is

Inventor

C. Amedio John

J. Bernard Paul

Fountain Mark

Original Assignee

Epix Pharmaceuticals, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-11

Filing date

1999-09-24

Publication date

1999-09-24

1999-09-24 Application filed by Epix Pharmaceuticals, Inc. filed Critical Epix Pharmaceuticals, Inc.

1999-09-24 Publication of IS5193A publication Critical patent/IS5193A/is

2005-03-15 Publication of IS1994B publication Critical patent/IS1994B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

IS5193A 1997-04-11 1999-09-24 Ferli til að smíða fosfódíestera IS1994B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/833,745 US5919967A (en)	1997-04-11	1997-04-11	Process for synthesizing phosphodiesters
PCT/US1998/001473 WO1998046612A1 (en)	1997-04-11	1998-01-27	Process for synthesizing phosphodiesters

Publications (2)

Publication Number	Publication Date
IS5193A true IS5193A (is)	1999-09-24
IS1994B IS1994B (is)	2005-03-15

Family

ID=25265165

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5193A IS1994B (is)	1997-04-11	1999-09-24	Ferli til að smíða fosfódíestera

Country Status (21)

Country	Link
US (1)	US5919967A (is)
EP (1)	EP1021452B1 (is)
JP (2)	JP4014231B2 (is)
KR (2)	KR100593650B1 (is)
AT (1)	ATE236171T1 (is)
AU (1)	AU728902B2 (is)
BR (1)	BR9809084B1 (is)
CA (1)	CA2285417C (is)
CZ (1)	CZ294469B6 (is)
DE (1)	DE69812983T2 (is)
DK (1)	DK1021452T3 (is)
ES (1)	ES2195315T3 (is)
HU (1)	HU224257B1 (is)
IL (1)	IL131964A (is)
IS (1)	IS1994B (is)
NO (1)	NO325619B1 (is)
NZ (1)	NZ337921A (is)
PL (1)	PL188258B1 (is)
PT (1)	PT1021452E (is)
SK (1)	SK283832B6 (is)
WO (1)	WO1998046612A1 (is)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2303426C (en)	1997-10-02	2008-09-23	Epix Medical, Inc.	Contrast-enhanced diagnostic imaging method for monitoring interventional therapies
US20030203879A1 (en) *	1999-09-09	2003-10-30	Schering Ag	Calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.O)methyl]-1-[(4,4-diphenylcyclohexy)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.Kappa.N9,.Kappa 011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents
US6559330B1 (en) *	1999-09-09	2003-05-06	Schering Aktiengesellschaft	Calcium complex of [[(4r)-4-[bis{carboxy-.kappa.o)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.o)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.n6,.kappa.n9,.kappa.011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents
DE19964224B4 (de) *	1999-09-09	2005-09-01	Schering Ag	Pharmazeutische Mittel enthaltend Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.011]1-oxidato(6-)]-, tetrahydrogen (MS-325) und dessen Salze sowie Verfahren zur Herstellung der Mittel
WO2003029257A1 (de) *	2001-09-27	2003-04-10	Schering Aktiengesellschaft	(ethylen)-(propylen/butylen)-phosphodiester-triaminpentaessigsäure-derivate
US7794693B2 (en)	2002-03-01	2010-09-14	Bracco International B.V.	Targeting vector-phospholipid conjugates
US20050100963A1 (en)	2002-03-01	2005-05-12	Dyax Corporation	KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
SI2301587T1 (sl)	2002-03-01	2014-11-28	Dyax Corp.	KDR in VEGF/KDR vezavni peptidi in njihova uporaba pri diagnozi
US8623822B2 (en)	2002-03-01	2014-01-07	Bracco Suisse Sa	KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7261876B2 (en)	2002-03-01	2007-08-28	Bracco International Bv	Multivalent constructs for therapeutic and diagnostic applications
AU2004217894B2 (en)	2003-03-03	2010-07-15	Bracco International B.V.	Peptides that specifically bind HGF receptor (cMet) and uses thereof
KR100585219B1 (ko) *	2004-05-07	2006-06-01	주식회사 태평양	포스페이트 유도체 및 이의 제조방법
CN100487093C (zh) *	2006-03-15	2009-05-13	中国石油化工股份有限公司	一种亚磷酰胺酯类极压抗磨剂及其制备和应用
WO2010121133A2 (en)	2009-04-17	2010-10-21	The General Hospital Corporation	Multimodal imaging of fibrin
JP2012521352A (ja)	2009-03-19	2012-09-13	ワイス・エルエルシー	［２−（８，９−ジオキソ−２，６−ジアザビシクロ［５．２．０］ノナ−１（７）−エン−２−イル）エチル］ホスホン酸およびその前駆体を調製するための方法
WO2013009869A2 (en)	2011-07-11	2013-01-17	Integrated Diagnostics, Inc.	Akt-specific capture agents, compositions, and methods of using and making
TW201514188A (zh) *	2013-03-13	2015-04-16	Lantheus Medical Imaging Inc	製備釓磷維塞三鈉單水合物之方法
WO2015171543A1 (en)	2014-05-05	2015-11-12	California Institute Of Technology	Mutant akt-specific capture agents, compositions, and methods of using and making
US10471162B2 (en)	2014-06-20	2019-11-12	The General Hospital Corporation	Collagen targeted imaging probes
EP3270951B1 (en)	2015-03-16	2020-09-09	California Institute of Technology	Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making
IL256833B2 (en)	2015-07-15	2025-07-01	California Inst Of Techn	IL-17F-specific binding agents, compositions and methods of use and preparation
EP3519425B1 (en)	2016-09-29	2024-02-28	Indi Molecular, Inc.	Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same
US11358982B2 (en)	2016-11-01	2022-06-14	Ohio State Innovation Foundation	Methods for the iodination of biomolecules
EP3638687A1 (en)	2017-06-15	2020-04-22	Indi Molecular, Inc.	Il-17f and il-17a-specific capture agents, compositions, and methods of using and making
US11919972B2 (en)	2018-11-02	2024-03-05	Regeneron Pharmaceuticals, Inc.	Peptide libraries with non-canonical amino acids
WO2020097531A1 (en)	2018-11-08	2020-05-14	Indi Molecular, Inc.	Theranostic capture agents, compositions, and methods of using and making
US12201679B2 (en)	2019-04-05	2025-01-21	Institute For Systems Biology	Epitope-targeted peptide immunostimulants
WO2020236969A1 (en)	2019-05-20	2020-11-26	Indi Molecular, Inc.	Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1)
US11414460B2 (en)	2019-07-19	2022-08-16	Institute For Systems Biology	KRAS-specific capture agents, compositions, and methods of making and using
US12209142B2 (en)	2020-05-29	2025-01-28	Institute For Systems Biology	SARS-CoV-2 epitope-targeted peptide immunostimulants
WO2022098743A1 (en)	2020-11-03	2022-05-12	Indi Molecular, Inc.	Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)
WO2022098745A1 (en)	2020-11-03	2022-05-12	Indi Molecular, Inc.	Compositions, delivery systems, and methods useful in tumor therapy
JP7659787B2 (ja)	2021-03-03	2025-04-10	国立大学法人東京科学大学	非対称型リン酸トリエステルの製造方法、対称型リン酸トリエステルの製造方法、リン酸エステルの製造方法、及び、有機リン化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4647447A (en) *	1981-07-24	1987-03-03	Schering Aktiengesellschaft	Diagnostic media
US4880008A (en) *	1985-05-08	1989-11-14	The General Hospital Corporation	Vivo enhancement of NMR relaxivity
TW319763B (is) *	1995-02-01	1997-11-11	Epix Medical Inc
CA2214789A1 (en) *	1995-03-08	1996-09-12	The Scripps Research Institute	Carbopeptoids and carbonucleotoids

1997
- 1997-04-11 US US08/833,745 patent/US5919967A/en not_active Expired - Lifetime
1998
- 1998-01-27 PL PL98337423A patent/PL188258B1/pl not_active IP Right Cessation
- 1998-01-27 WO PCT/US1998/001473 patent/WO1998046612A1/en not_active Ceased
- 1998-01-27 HU HU0004239A patent/HU224257B1/hu not_active IP Right Cessation
- 1998-01-27 ES ES98903734T patent/ES2195315T3/es not_active Expired - Lifetime
- 1998-01-27 PT PT98903734T patent/PT1021452E/pt unknown
- 1998-01-27 CA CA002285417A patent/CA2285417C/en not_active Expired - Lifetime
- 1998-01-27 NZ NZ337921A patent/NZ337921A/xx not_active IP Right Cessation
- 1998-01-27 DK DK98903734T patent/DK1021452T3/da active
- 1998-01-27 AT AT98903734T patent/ATE236171T1/de active
- 1998-01-27 DE DE69812983T patent/DE69812983T2/de not_active Expired - Lifetime
- 1998-01-27 SK SK1382-99A patent/SK283832B6/sk not_active IP Right Cessation
- 1998-01-27 AU AU60425/98A patent/AU728902B2/en not_active Ceased
- 1998-01-27 KR KR1019997009256A patent/KR100593650B1/ko not_active Expired - Fee Related
- 1998-01-27 CZ CZ19993559A patent/CZ294469B6/cs not_active IP Right Cessation
- 1998-01-27 IL IL13196498A patent/IL131964A/en not_active IP Right Cessation
- 1998-01-27 KR KR1020067007449A patent/KR20060066122A/ko not_active Withdrawn
- 1998-01-27 EP EP98903734A patent/EP1021452B1/en not_active Expired - Lifetime
- 1998-01-27 JP JP54386798A patent/JP4014231B2/ja not_active Expired - Fee Related
- 1998-01-27 BR BRPI9809084-4A patent/BR9809084B1/pt not_active IP Right Cessation
1999
- 1999-09-24 IS IS5193A patent/IS1994B/is unknown
- 1999-10-08 NO NO19994919A patent/NO325619B1/no not_active IP Right Cessation
2005
- 2005-02-21 JP JP2005044872A patent/JP2005206605A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
KR100593650B1 (ko)	2006-07-03
SK138299A3 (en)	2000-05-16
SK283832B6 (sk)	2004-02-03
US5919967A (en)	1999-07-06
IS1994B (is)	2005-03-15
ATE236171T1 (de)	2003-04-15
JP2005206605A (ja)	2005-08-04
NZ337921A (en)	2000-09-29
DE69812983T2 (de)	2004-01-08
IL131964A0 (en)	2001-03-19
PL337423A1 (en)	2000-08-14
PT1021452E (pt)	2003-08-29
CZ355999A3 (cs)	2000-01-12
BR9809084B1 (pt)	2010-12-14
AU6042598A (en)	1998-11-11
AU728902B2 (en)	2001-01-18
NO994919L (no)	1999-10-08
DE69812983D1 (de)	2003-05-08
CA2285417A1 (en)	1998-10-22
IL131964A (en)	2004-01-04
EP1021452B1 (en)	2003-04-02
EP1021452A1 (en)	2000-07-26
NO325619B1 (no)	2008-06-30
HU224257B1 (hu)	2005-07-28
WO1998046612A1 (en)	1998-10-22
DK1021452T3 (da)	2003-08-18
JP2002511060A (ja)	2002-04-09
KR20010006177A (ko)	2001-01-26
CA2285417C (en)	2006-01-24
BR9809084A (pt)	2000-08-01
ES2195315T3 (es)	2003-12-01
NO994919D0 (no)	1999-10-08
JP4014231B2 (ja)	2007-11-28
HUP0004239A2 (en)	2001-03-28
HUP0004239A3 (en)	2001-11-28
CZ294469B6 (cs)	2005-01-12
KR20060066122A (ko)	2006-06-15
PL188258B1 (pl)	2005-01-31

Publication	Publication Date	Title
IS1994B (is)	2005-03-15	Ferli til að smíða fosfódíestera
ES2180141T3 (es)	2003-02-01	Procedimiento de produccion de acido 4-amino-1-hidroxibutiliden-1,1-bifosfonico o sus sales.
IE881366L (en)	1988-11-08	Dipyridoxyl phosphate NMRI contrast agents
ATE141278T1 (de)	1996-08-15	Diphosphonsaurederivate als zwischenprodukte zur herstellung von diphosphinliganden
ES2184785T3 (es)	2003-04-16	Agente de fosforilacion, procedimiento y uso.
FI883207A0 (fi)	1988-07-05	Foerfarande foer framstaellning av aminometylenfosfonoalkylfosfinater.
HUT45541A (en)	1988-07-28	Plant protecting compositions containing ester of phosphoric acid as active component and process for producing the active component
ES382819A1 (es)	1972-11-16	Procedimiento para la obtencion de esteres de acidos tria- zolo-tiazol (tiono)-fosforicos-fosfonicos y fosfinicos.
ATE388156T1 (de)	2008-03-15	Verfahren zur herstellung von ethylen-1,2- diphosphonsäuren
FI921057A0 (fi)	1992-03-11	Process foer framstaellningen av peroxykarboxylsyror med anvaendning av en enzymkatalysator.
MY110796A (en)	1999-04-30	Process for the manufacture of aminomethanephosphonic acid
GB1514099A (en)	1978-06-14	Thymol blue monophosphate salts and diagnostic method using same
ES484569A1 (es)	1980-10-01	Procedimiento para preparar una composicion insecticida a base de fosfatos y fosfanatos de pirazol.
JPS53144558A (en)	1978-12-15	Color protection of beta-naphthol
JPS57183796A (en)	1982-11-12	Preparation of organophosphoric acid ester substituted with alkylsulfinyl group
GB1249595A (en)	1971-10-13	(thiono)phosphoric(phosphonic)-acid esters and ester amides
YU24396A (sh)	1998-11-05	Postupak za dobijanje 1-hidroksibisfosfonata
ES463860A1 (es)	1979-01-01	Procedimiento para preparar anhidridos de acidos organofos- foricos
ES460183A1 (es)	1978-12-01	Procedimiento para la obtencion de amidas-esteres o-(1-fluo-ro-2-halogeno-etilicos) de los acidos (tiono)-fosfo-ricos (-nicos).
JPS56166197A (en)	1981-12-21	O-alkyl s-alkyl or -aryl thiophosphoric chloride