IS2315B - New branched substituted amino derivatives of 3-amino-1-phenyl-1H [1,2,4] triazole, methods for their preparation and pharmaceutical compositions containing them - Google Patents

New branched substituted amino derivatives of 3-amino-1-phenyl-1H [1,2,4] triazole, methods for their preparation and pharmaceutical compositions containing them

Info

Publication number: IS2315B
Authority: IS; Iceland
Prior art keywords: amino; triazole; phenyl; preparation; methods
Prior art date: 1999-12-17

Application number

IS6402A

Other languages

Icelandic (is)

Other versions

IS6402A (en

Inventor

Geslin Michel

Gully Danielle

Maffrand Jean-Pierre

Roger Pierre

Original Assignee

Sanofi-Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-17

Filing date

2002-05-28

Publication date

2007-11-15

2002-05-28 Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis

2002-05-28 Publication of IS6402A publication Critical patent/IS6402A/en

2007-11-15 Publication of IS2315B publication Critical patent/IS2315B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Gynecology & Obstetrics (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Pregnancy & Childbirth (AREA)
Nutrition Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IS6402A 1999-12-17 2002-05-28 New branched substituted amino derivatives of 3-amino-1-phenyl-1H [1,2,4] triazole, methods for their preparation and pharmaceutical compositions containing them IS2315B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9915935A FR2802530B1 (en)	1999-12-17	1999-12-17	NOVEL BRANCHED SUBSTITUTED AMINO DERIVATIVES OF 3-AMINO-1-PHENYL-1H [1,2,4] TRIAZOLE, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PCT/FR2000/003536 WO2001044207A2 (en)	1999-12-17	2000-12-14	Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them

Publications (2)

Publication Number	Publication Date
IS6402A IS6402A (en)	2002-05-28
IS2315B true IS2315B (en)	2007-11-15

Family

ID=9553380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS6402A IS2315B (en)	1999-12-17	2002-05-28	New branched substituted amino derivatives of 3-amino-1-phenyl-1H [1,2,4] triazole, methods for their preparation and pharmaceutical compositions containing them

Country Status (33)

Country	Link
US (1)	US6806282B2 (en)
EP (1)	EP1242389B1 (en)
JP (1)	JP4146641B2 (en)
KR (1)	KR100705525B1 (en)
CN (1)	CN1293061C (en)
AR (1)	AR031837A1 (en)
AT (1)	ATE264847T1 (en)
AU (1)	AU780711B2 (en)
BR (1)	BR0017023A (en)
CA (1)	CA2398772C (en)
CO (1)	CO5251379A1 (en)
CZ (1)	CZ302460B6 (en)
DE (1)	DE60010126T2 (en)
DK (1)	DK1242389T3 (en)
EA (1)	EA004957B1 (en)
EE (1)	EE04778B1 (en)
ES (1)	ES2219436T3 (en)
FR (1)	FR2802530B1 (en)
HU (1)	HUP0204080A3 (en)
IL (2)	IL150037A0 (en)
IS (1)	IS2315B (en)
ME (1)	MEP12108A (en)
MX (1)	MXPA02006033A (en)
NO (1)	NO20022828L (en)
PL (1)	PL203819B1 (en)
PT (1)	PT1242389E (en)
RS (1)	RS50289B (en)
SK (1)	SK285994B6 (en)
TR (2)	TR200401775T4 (en)
TW (1)	TWI289554B (en)
UA (1)	UA73333C2 (en)
WO (1)	WO2001044207A2 (en)
ZA (1)	ZA200204422B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2004263148B2 (en) *	2003-08-06	2008-08-21	Vertex Pharmaceuticals, Incorporated	Aminotriazole compounds useful as inhibitors of protein kinases
JO3019B1 (en)	2006-04-19	2016-09-05	Janssen Pharmaceutica Nv	Trisubstituted 1,2,4-Triazoles
CN101827836B (en)	2007-10-18	2014-02-19	詹森药业有限公司	Trisubstituted 1,2,4-triazole compounds
JO2784B1 (en)	2007-10-18	2014-03-15	شركة جانسين فارماسوتيكا ان. في	1,3,5-trisubstitued triazole derivative
EP2257535B1 (en) *	2008-03-19	2013-11-06	Janssen Pharmaceutica N.V.	Trisubstituted 1,2,4-triazoles as nicotinic acetylcholine receptor modulators
TWI440634B (en)	2008-05-09	2014-06-11	Janssen Pharmaceutica Nv	Trisubstituted pyrazoles
EP2629616A4 (en) *	2010-10-21	2014-03-26	Merck Sharp & Dohme	AMINO-TRIAZOLYLES INHIBITORS OF PED10
HUE068315T2 (en)	2014-01-21	2024-12-28	Neurocrine Biosciences Inc	Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia
CN104059027B (en) *	2014-07-01	2015-10-28	河北大学	One class contains (E)-methoxyimino methyl phenylacetate compounds of 1,2,4-triazole and its production and use
SG11202105930QA (en)	2018-12-07	2021-07-29	Neurocrine Biosciences Inc	Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
MX2022002881A (en) *	2019-09-25	2022-06-08	Oncoarendi Therapeutics Sa	Process for the production of 5-(4-((2 s,5 s)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl) -1 h-1,2,4-triazol-3-amine.
CN114502162B (en)	2019-09-27	2025-03-28	纽罗克里生物科学有限公司	CRF receptor antagonists and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0285893B1 (en) *	1987-03-27	1992-03-18	Kumiai Chemical Industry Co., Ltd.	Phenyltriazole derivative and insecticide
US5795905A (en) *	1995-06-06	1998-08-18	Neurocrine Biosciences, Inc.	CRF receptor antagonists and methods relating thereto
FR2763337B1 (en) *	1997-05-13	1999-08-20	Sanofi Sa	NOVEL TRIAZOLE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

1999
- 1999-12-17 FR FR9915935A patent/FR2802530B1/en not_active Expired - Fee Related
2000
- 2000-12-14 KR KR1020027007736A patent/KR100705525B1/en not_active Expired - Fee Related
- 2000-12-14 HU HU0204080A patent/HUP0204080A3/en unknown
- 2000-12-14 SK SK850-2002A patent/SK285994B6/en not_active IP Right Cessation
- 2000-12-14 PT PT00988916T patent/PT1242389E/en unknown
- 2000-12-14 TR TR2004/01775T patent/TR200401775T4/en unknown
- 2000-12-14 EP EP00988916A patent/EP1242389B1/en not_active Expired - Lifetime
- 2000-12-14 MX MXPA02006033A patent/MXPA02006033A/en active IP Right Grant
- 2000-12-14 AU AU25259/01A patent/AU780711B2/en not_active Ceased
- 2000-12-14 UA UA2002064623A patent/UA73333C2/en unknown
- 2000-12-14 PL PL355811A patent/PL203819B1/en not_active IP Right Cessation
- 2000-12-14 US US10/149,499 patent/US6806282B2/en not_active Expired - Lifetime
- 2000-12-14 RS YUP-439/02A patent/RS50289B/en unknown
- 2000-12-14 AT AT00988916T patent/ATE264847T1/en active
- 2000-12-14 EE EEP200200331A patent/EE04778B1/en not_active IP Right Cessation
- 2000-12-14 ES ES00988916T patent/ES2219436T3/en not_active Expired - Lifetime
- 2000-12-14 CO CO00095200A patent/CO5251379A1/en not_active Application Discontinuation
- 2000-12-14 CZ CZ20022099A patent/CZ302460B6/en not_active IP Right Cessation
- 2000-12-14 ME MEP-121/08A patent/MEP12108A/en unknown
- 2000-12-14 JP JP2001544697A patent/JP4146641B2/en not_active Expired - Lifetime
- 2000-12-14 WO PCT/FR2000/003536 patent/WO2001044207A2/en not_active Ceased
- 2000-12-14 IL IL15003700A patent/IL150037A0/en active IP Right Grant
- 2000-12-14 DE DE60010126T patent/DE60010126T2/en not_active Expired - Lifetime
- 2000-12-14 TR TR2002/01600T patent/TR200201600T2/en unknown
- 2000-12-14 BR BR0017023-2A patent/BR0017023A/en active Search and Examination
- 2000-12-14 EA EA200200523A patent/EA004957B1/en not_active IP Right Cessation
- 2000-12-14 CA CA2398772A patent/CA2398772C/en not_active Expired - Fee Related
- 2000-12-14 CN CNB00819078XA patent/CN1293061C/en not_active Expired - Fee Related
- 2000-12-14 DK DK00988916T patent/DK1242389T3/en active
- 2000-12-15 AR ARP000106666A patent/AR031837A1/en not_active Application Discontinuation
2001
- 2001-01-29 TW TW089126997A patent/TWI289554B/en not_active IP Right Cessation
2002
- 2002-05-04 IL IL150037A patent/IL150037A/en not_active IP Right Cessation
- 2002-05-28 IS IS6402A patent/IS2315B/en unknown
- 2002-06-03 ZA ZA200204422A patent/ZA200204422B/en unknown
- 2002-06-13 NO NO20022828A patent/NO20022828L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
CZ302460B6 (en)	2011-06-01
EP1242389B1 (en)	2004-04-21
IL150037A (en)	2007-02-11
AU780711B2 (en)	2005-04-14
CN1434808A (en)	2003-08-06
PL203819B1 (en)	2009-11-30
IL150037A0 (en)	2002-12-01
HUP0204080A3 (en)	2005-01-28
ZA200204422B (en)	2003-11-26
WO2001044207A3 (en)	2001-12-20
WO2001044207B1 (en)	2002-06-06
SK8502002A3 (en)	2003-02-04
YU43902A (en)	2005-03-15
AR031837A1 (en)	2003-10-08
HK1055947A1 (en)	2004-01-30
TR200201600T2 (en)	2002-10-21
MEP12108A (en)	2010-06-10
EA200200523A1 (en)	2002-12-26
JP4146641B2 (en)	2008-09-10
DK1242389T3 (en)	2004-08-09
KR100705525B1 (en)	2007-04-10
DE60010126D1 (en)	2004-05-27
ATE264847T1 (en)	2004-05-15
JP2003516975A (en)	2003-05-20
EA004957B1 (en)	2004-10-28
TR200401775T4 (en)	2004-09-21
CO5251379A1 (en)	2003-02-28
EE04778B1 (en)	2007-02-15
CA2398772C (en)	2011-07-05
KR20020061002A (en)	2002-07-19
HUP0204080A2 (en)	2003-04-28
FR2802530A1 (en)	2001-06-22
DE60010126T2 (en)	2005-04-28
CZ20022099A3 (en)	2002-09-11
US20030162771A1 (en)	2003-08-28
SK285994B6 (en)	2008-01-07
WO2001044207A8 (en)	2001-07-12
RS50289B (en)	2009-09-08
PL355811A1 (en)	2004-05-17
ES2219436T3 (en)	2004-12-01
TWI289554B (en)	2007-11-11
IS6402A (en)	2002-05-28
PT1242389E (en)	2004-08-31
NO20022828D0 (en)	2002-06-13
MXPA02006033A (en)	2003-01-28
BR0017023A (en)	2002-12-03
CA2398772A1 (en)	2001-06-21
EP1242389A2 (en)	2002-09-25
US6806282B2 (en)	2004-10-19
CN1293061C (en)	2007-01-03
AU2525901A (en)	2001-06-25
FR2802530B1 (en)	2002-02-22
EE200200331A (en)	2003-06-16
NO20022828L (en)	2002-08-19
UA73333C2 (en)	2005-07-15
WO2001044207A2 (en)	2001-06-21

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