[go: up one dir, main page]

IN2014DN11181A - - Google Patents

Info

Publication number
IN2014DN11181A
IN2014DN11181A IN11181DEN2014A IN2014DN11181A IN 2014DN11181 A IN2014DN11181 A IN 2014DN11181A IN 11181DEN2014 A IN11181DEN2014 A IN 11181DEN2014A IN 2014DN11181 A IN2014DN11181 A IN 2014DN11181A
Authority
IN
India
Prior art keywords
apc
treat
individual
methods
effective amount
Prior art date
Application number
Other languages
English (en)
Inventor
Christopher John Jackson
Meilang Xue
Original Assignee
Univ Sydney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902874A external-priority patent/AU2012902874A0/en
Application filed by Univ Sydney filed Critical Univ Sydney
Publication of IN2014DN11181A publication Critical patent/IN2014DN11181A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IN11181DEN2014 2012-07-04 2013-07-04 IN2014DN11181A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2012902874A AU2012902874A0 (en) 2012-07-04 Treatment of inflammatory skin disorders
PCT/AU2013/000729 WO2014005183A1 (fr) 2012-07-04 2013-07-04 Traitement de troubles cutanés inflammatoires

Publications (1)

Publication Number Publication Date
IN2014DN11181A true IN2014DN11181A (fr) 2015-10-02

Family

ID=49881162

Family Applications (1)

Application Number Title Priority Date Filing Date
IN11181DEN2014 IN2014DN11181A (fr) 2012-07-04 2013-07-04

Country Status (12)

Country Link
US (3) US20150150954A1 (fr)
EP (1) EP2869833B1 (fr)
JP (1) JP6273272B2 (fr)
KR (1) KR102068010B1 (fr)
CN (1) CN104394883B (fr)
AU (1) AU2013286812B2 (fr)
BR (1) BR112015000051A2 (fr)
CA (1) CA2877745C (fr)
ES (1) ES2676422T3 (fr)
IN (1) IN2014DN11181A (fr)
RU (1) RU2662564C2 (fr)
WO (1) WO2014005183A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015000051A2 (pt) * 2012-07-04 2017-06-27 Univ Sydney tratamento de distúrbios inflamatórios da pele
JP6873387B2 (ja) * 2014-04-16 2021-05-19 ジージー バイオテック エルエルシー 創傷治癒に対するａｐｃ類似体の使用
AU2014391082B2 (en) * 2014-04-16 2020-04-09 Zz Biotech Llc Treatment of abnormal cutaneous scarring
CN108779115B (zh) 2016-10-14 2021-02-26 江苏恒瑞医药股份有限公司 五元杂芳环并桥环类衍生物、其制备方法及其在医药上的应用
KR20210042268A (ko) 2018-05-30 2021-04-19 다이렉트 바이오로직스 엘엘씨 간엽 줄기 세포(msc) 제제를 포함하는 성장 인자 및 세포외 소포 냉동 또는 분말화 첨가제 및 사용 방법
US20210268062A1 (en) * 2018-06-28 2021-09-02 Novapep Pty Ltd Inflammatory skin disorder treatment
CN109337974B (zh) * 2018-12-14 2022-01-25 北京蛋白质组研究中心 一种检测银屑病的诊断标志物的试剂及其应用
US20220079990A1 (en) * 2018-12-26 2022-03-17 Direct Biologics Llc Methods and compositions for treating skin and hair disorders
RU2704322C1 (ru) * 2019-06-11 2019-10-28 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Крем с секретомом мультипотентных мезенхимальных стромальных клеток для коррекции псориазиформного воспаления в эксперименте
CA3146433A1 (fr) 2019-07-18 2021-01-21 Direct Biologics Llc Preparations comprenant des cellules souches mesenchymateuses ainsi que des cannabinoides et leurs procedes d'utilisation
US12502407B2 (en) 2024-04-25 2025-12-23 Direct Biologics, Llc Treatment of fistula with bone marrow mesenchymal stem cell derived extracellular vesicles

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
US4959318A (en) 1985-06-27 1990-09-25 Zymogenetics, Inc. Expression of protein C
US5516650A (en) 1985-06-27 1996-05-14 Zymogenetics, Inc. Production of activated protein C
WO1989012685A1 (fr) 1987-05-18 1989-12-28 Integrated Genetics, Inc. Molecules de proteine c ameliorees et procede de production et d'activation de telles molecules
US5084274A (en) 1987-11-17 1992-01-28 Scripps Clinic And Research Foundation Inhibition of arterial thrombotic occlusion or thromboembolism
US4981952A (en) 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
US5093117A (en) 1989-01-24 1992-03-03 Baxter International Inc. Compositions and method for the treatment or prophylaxis of sepsis or septic shock
US5571786A (en) 1990-08-16 1996-11-05 Immuno Aktiengesellschaft Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
AT402260B (de) * 1990-08-16 1997-03-25 Immuno Ag Protein c-hältige pharmazeutische präparation
AT397615B (de) * 1991-05-14 1994-05-25 Immuno Ag Arzneimittel enthaltend protein c
WO1993009807A1 (fr) 1991-11-18 1993-05-27 The Scripps Research Institute Procedes d'inhibition de la thrombose par elevation des taux de proteine c activee endogene dans la circulation
MY110664A (en) 1992-05-21 1999-01-30 Lilly Co Eli Protein c derivatives
DE4239150A1 (de) 1992-11-20 1994-05-26 Thomae Gmbh Dr K O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
JP3043558B2 (ja) 1993-10-29 2000-05-22 財団法人化学及血清療法研究所 ヒト活性化プロテインｃ調製物及びその製法
WO1995030429A1 (fr) 1994-05-04 1995-11-16 Board Of Trustees Of The University Of Arkansas Nouvelles utilisations ophtalmologiques de la proteine c
BR9809304B1 (pt) 1997-04-28 2011-02-08 formulação liofilizada estável, processo para preparação da mesma, bem como forma de dosagem unitária.
HUP0001237A3 (en) 1997-10-20 2002-01-28 Lilly Co Eli Methods for treating vascular disorders
EP1255556B1 (fr) 2000-02-04 2011-04-06 The Scripps Research Institute Utilisations a des fins neuroprotectrices, antithrombotiques et anti-inflammatoires de la proteine c activee
CA2400187A1 (fr) 2000-02-11 2001-08-16 Eli Lilly And Company Derives de la proteine c
WO2001072328A2 (fr) * 2000-03-28 2001-10-04 Eli Lilly And Company Methodes de traitement de maladies a l'aide de la proteine c activee
CA2425221A1 (fr) 2000-10-18 2002-04-25 Maxygen Aps Molecules de proteine c ou de type proteine c activee
ES2384099T3 (es) * 2001-06-13 2012-06-29 The University Of Sydney Proteína C para cicatrización de heridas
AU2003275948A1 (en) * 2002-11-06 2004-06-07 Novo Nordisk A/S Pharmaceutical composition comprising a tissue factor antagonist and protein c polypeptides
DE50304744D1 (de) 2003-04-28 2006-10-05 Biofrontera Bioscience Gmbh Verwendung von Riluzole kombiniert mit geeigneten Hilfs-und Zusatzstoffen zur Behandlung von Krankheiten, die durch eine Hyperproliferation von Keratinozyten gekennzeichnet sind, insbesondere Neurodermitis und Psoriasis
US9192657B2 (en) 2003-07-08 2015-11-24 The Scripps Research Institute Activated protein C variants with normal cytoprotective activity but reduced anticoagulant activity
JP4986618B2 (ja) 2003-07-08 2012-07-25 ザ スクリプス リサーチ インスティチュート 通常の細胞保護活性を有するが抗凝固活性が低下した活性化プロテインｃ変異体
EP1688161A1 (fr) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Utilisation du pirlindole dans le traitement des maladies caracterisées par la prolifération des lymphocytes t et/ou par l'hyperproliferation de kerationcytes, notamment la dermatite atopique et le psoriasis
EP1841442A4 (fr) * 2005-01-07 2009-12-09 Northern Sydney And Central Co Traitement des états pathologiques auto-immuns et inflammatoires
US20070224150A1 (en) * 2005-03-24 2007-09-27 Yongji Chung Growth factor for hair and skin treatment
ZA200800251B (en) 2005-06-24 2009-04-29 Drugrecure Aps Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory track
EP2468752A1 (fr) * 2005-08-04 2012-06-27 Sirtris Pharmaceuticals, Inc. Dérivés de thiazolopyridine comme modulateurs de sirtuine
GR1005700B (el) * 2006-09-01 2007-10-22 (40%) ����� �������� Τροπος αντιμετωπισης της 1ης φασης του εγκαυματοσσε μη σηπτικους ασθενεις με συνεχη ενδοφλεβια χορηγηση ενεργοποιημενης πρωτεινης-c για 48 ωρες με στοχο τη μειωση της τελικης εγκαυματικης βλαβης καιαυξηση της ταχυτητας επουλωσης κατα τα πρωτα επτα μετεγκαυματικα 24ωρα
US20100284997A1 (en) 2006-10-31 2010-11-11 Griffin John H Dosing regimen of activated protein c and variants having reduced anticoagulant activity
GB0724231D0 (en) 2007-12-12 2008-01-30 Renono Ltd Methods for inhibiting scarring
ES2316312B1 (es) * 2008-06-20 2010-02-08 Ignacio Umbert Millet Composicion farmaceutica dermatologica para el tratamiento de patologias de inflamacion de la piel, tales como por ejemplo dermatitis, dermatitis atopica, vitiligo, alopecia areata, acne, psoriasis y prurito,y combinaciones de las mismas.
EP2157176A1 (fr) * 2008-08-20 2010-02-24 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Variantes de la protéine C
CA2759201A1 (fr) * 2009-04-01 2010-10-07 The Medical Research, Infrastructure, And Health Services Fund Of The Te L Aviv Medical Center Procede de regulation de la proliferation et de la differenciation des keratinocytes
CN101912450A (zh) * 2010-09-01 2010-12-15 吴业刚 一种治疗脚气皮炎的中西药组合物及其制备方法
BR112015000051A2 (pt) * 2012-07-04 2017-06-27 Univ Sydney tratamento de distúrbios inflamatórios da pele
AU2014391082B2 (en) 2014-04-16 2020-04-09 Zz Biotech Llc Treatment of abnormal cutaneous scarring
JP6873387B2 (ja) 2014-04-16 2021-05-19 ジージー バイオテック エルエルシー 創傷治癒に対するａｐｃ類似体の使用
US20210268062A1 (en) * 2018-06-28 2021-09-02 Novapep Pty Ltd Inflammatory skin disorder treatment

Also Published As

Publication number Publication date
US11617785B2 (en) 2023-04-04
EP2869833A1 (fr) 2015-05-13
CA2877745C (fr) 2021-11-30
JP2015521632A (ja) 2015-07-30
RU2662564C2 (ru) 2018-07-26
CN104394883A (zh) 2015-03-04
RU2015103510A (ru) 2016-08-27
BR112015000051A2 (pt) 2017-06-27
AU2013286812A1 (en) 2015-01-22
JP6273272B2 (ja) 2018-01-31
WO2014005183A1 (fr) 2014-01-09
HK1204573A1 (en) 2015-11-27
AU2013286812B2 (en) 2017-04-20
US20170080062A1 (en) 2017-03-23
EP2869833B1 (fr) 2018-04-04
ES2676422T3 (es) 2018-07-19
CA2877745A1 (fr) 2014-01-09
US20150150954A1 (en) 2015-06-04
KR20150036351A (ko) 2015-04-07
CN104394883B (zh) 2017-05-31
US20200276281A1 (en) 2020-09-03
KR102068010B1 (ko) 2020-01-20
EP2869833A4 (fr) 2015-11-18

Similar Documents

Publication Publication Date Title
IN2014DN11181A (fr)
PH12018500452A1 (en) Novel modulators and methods of use
PH12015500525A1 (en) Formulations of enzalutamide
MY167585A (en) Disposable diaper
UA110813C2 (uk) Лікування ліподистрофії
GEP201706695B (en) Substituted 4-phenyl-pyridi-nes for the treatment of nk-1 receptor related diseases
BR112014017799A8 (pt) Compostos inibidores de metaloenzima
MY165759A (en) Pull-on diaper
IN2014DN00288A (fr)
IN2014DN00286A (fr)
IN2014MN00093A (fr)
IN2014MN01378A (fr)
IN2014DN08481A (fr)
MY168032A (en) Warm-Cool Beauty Treatment Device
PL2890793T3 (pl) Wytwarzanie lotnych dienów przez dehydratację enzymatyczną (EC 4.2.1.127) lekkich alkenoli
IN2014DN06792A (fr)
UY34652A (es) Anticuerpos humanos frente a toxinas de clostridium difficile
MX2015002487A (es) Proceso para la preparacion de teneligliptina.
MY166103A (en) Disposable diaper
MX2016004540A (es) Tiazolopirimidinonas como moduladores de la actividad de receptores de n-metil-d-aspartato (nmda).
MY167652A (en) Disposable diaper
SG10201703677VA (en) Methods of treating s. aureus-associated diseases
MX2015006337A (es) Metodos y composiciones para tratar enfermedades neurodegenerativas.
GEP201706626B (en) Synthesis of (s)-nifuratel
GEP201706764B (en) Quinazolin-thf-amines as pde1 inhibitors