[go: up one dir, main page]

IN2012DN06720A - - Google Patents

Info

Publication number
IN2012DN06720A
IN2012DN06720A IN6720DEN2012A IN2012DN06720A IN 2012DN06720 A IN2012DN06720 A IN 2012DN06720A IN 6720DEN2012 A IN6720DEN2012 A IN 6720DEN2012A IN 2012DN06720 A IN2012DN06720 A IN 2012DN06720A
Authority
IN
India
Prior art keywords
disease
treatment
present disclosure
disclosure relates
pharmaceutical formulations
Prior art date
Application number
Other languages
English (en)
Inventor
Dingjiang Liu
Holly Zhuohong Huang
David Andrew Martin
Christopher Boyd Russell
David H Salinger
Scott Walter Baumgartner
Christopher J Endres
Original Assignee
Kirin Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43858045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN06720(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kirin Amgen Inc filed Critical Kirin Amgen Inc
Publication of IN2012DN06720A publication Critical patent/IN2012DN06720A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
IN6720DEN2012 2010-01-15 2011-01-12 IN2012DN06720A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29538710P 2010-01-15 2010-01-15
US42205910P 2010-12-10 2010-12-10
PCT/US2011/020985 WO2011088120A1 (fr) 2010-01-15 2011-01-12 Formulation d'anticorps et régimes thérapeutiques

Publications (1)

Publication Number Publication Date
IN2012DN06720A true IN2012DN06720A (fr) 2015-10-23

Family

ID=43858045

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6720DEN2012 IN2012DN06720A (fr) 2010-01-15 2011-01-12

Country Status (38)

Country Link
US (5) US8883151B2 (fr)
EP (3) EP2523688B1 (fr)
JP (2) JP5743234B2 (fr)
KR (1) KR101766936B1 (fr)
CN (1) CN102821787B (fr)
AR (1) AR079903A1 (fr)
AU (3) AU2011205402B2 (fr)
BR (1) BR112012017150B1 (fr)
CA (1) CA2787128C (fr)
CL (1) CL2012001966A1 (fr)
CO (1) CO6640206A2 (fr)
CR (1) CR20120419A (fr)
CY (2) CY1119852T1 (fr)
DK (2) DK3295957T3 (fr)
EA (2) EA031209B9 (fr)
ES (2) ES2753216T3 (fr)
HR (1) HRP20171939T1 (fr)
HU (2) HUE046670T2 (fr)
IL (1) IL220602B (fr)
IN (1) IN2012DN06720A (fr)
LT (2) LT3295957T (fr)
MA (1) MA33989B1 (fr)
MX (1) MX349856B (fr)
MY (1) MY182680A (fr)
NO (1) NO2523688T3 (fr)
NZ (1) NZ601125A (fr)
PE (1) PE20121691A1 (fr)
PH (1) PH12012501364A1 (fr)
PL (2) PL3295957T3 (fr)
PT (2) PT3295957T (fr)
RS (2) RS59743B1 (fr)
SG (2) SG10201604093XA (fr)
SI (2) SI2523688T1 (fr)
TN (1) TN2012000335A1 (fr)
TW (1) TWI554282B (fr)
UA (1) UA112288C2 (fr)
WO (1) WO2011088120A1 (fr)
ZA (1) ZA201205167B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7833527B2 (en) 2006-10-02 2010-11-16 Amgen Inc. Methods of treating psoriasis using IL-17 Receptor A antibodies
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
ES2753216T3 (es) 2010-01-15 2020-04-07 Amgen K A Inc Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis
KR101912169B1 (ko) * 2010-02-04 2018-10-26 체에스엘 베링 아게 면역글로불린 제제
AU2011254557B2 (en) 2010-05-20 2015-09-03 Ablynx Nv Biological materials related to HER3
MX383982B (es) 2010-09-22 2025-03-14 Amgen Inc Inmunoglobulinas portadoras y usos de las mismas.
SG193963A1 (en) * 2011-04-07 2013-11-29 Glaxosmithkline Llc Formulations with reduced viscosity
UA117218C2 (uk) 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
JOP20200043A1 (ar) 2011-05-10 2017-06-16 Amgen Inc طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
US20140234330A1 (en) * 2011-07-22 2014-08-21 Amgen Inc. Il-17 receptor a is required for il-17c biology
WO2013078375A2 (fr) * 2011-11-23 2013-05-30 Amgen Inc. Administration d'un anticorps spécifique hétérodimère anti-alpha-4-bêta-7
DK2822590T3 (en) * 2012-03-07 2017-01-23 Lilly Co Eli IL-17 antibody formulation
WO2013170977A1 (fr) 2012-05-14 2013-11-21 Novo Nordisk A/S Solutions protéiques stabilisées
EA201591579A1 (ru) 2013-03-15 2016-01-29 Амген Инк. Способы лечения болезни крона при помощи анти-il-23 антитела
EP2968488A1 (fr) 2013-03-15 2016-01-20 Amgen Inc. Méthodes de traitement du psoriasis à l'aide d'un anticorps anti-il-23
WO2015153144A1 (fr) 2014-03-31 2015-10-08 Kirin-Amgen, Inc. Procédés de traitement du psoriasis des ongles et du cuir chevelu
EP3143404B1 (fr) 2014-05-16 2018-08-29 Amgen Inc. Dosage pour la détection de populations de cellules th1 et th2
JP6663910B2 (ja) * 2014-08-26 2020-03-13 アムジェン ケー・エー，インコーポレイテッド 抗ＴＮＦ−α抗体療法を受けた乾癬患者を治療するための方法
EP3193171B1 (fr) * 2014-09-10 2019-05-29 NOF Corporation Utilisation d'un inhibiteur d'adsorption de protéine et procédé d'inhibition d'adsorption de protéine
AU2015357068B2 (en) 2014-12-03 2021-07-29 Csl Behring Ag Pharmaceutical product with increased stability comprising immunoglobulins
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
CN116672446A (zh) 2015-09-17 2023-09-01 美国安进公司 使用il23途径生物标志物预测il23拮抗剂的临床应答
CA3002761A1 (fr) 2015-11-04 2017-05-11 Astrazeneca Ab Dipeptidyl peptidase-4 et periostine utilisees comme predicteurs d'une reponse clinique a des agents therapeutiques cibles sur les eosinophiles dans des maladies eosinophiles
RU2018124603A (ru) 2015-12-22 2020-01-24 Эмджен Инк. Ccl20 как прогностический фактор клинического ответа на антагонисты ил-23
CN114265251B (zh) 2016-04-19 2024-12-06 Sage电致变色显示有限公司 包括透明导电氧化物层和汇流条的电致变色装置和其形成方法
GB201612043D0 (en) * 2016-07-11 2016-08-24 Crescendo Biologics Ltd Composition for treatment of disorders
CA2974531A1 (fr) * 2017-07-26 2019-01-26 Michael Giroux Ancrage de securite et event de toit
GB201719447D0 (en) 2017-11-23 2018-01-10 Ucb Biopharma Sprl Pharmaceutical composition
SG11202100185VA (en) 2018-07-13 2021-02-25 Astrazeneca Collaboration Ventures Llc Treating ulcerative colitis with brazikumab
PH12021551916A1 (en) 2019-02-18 2022-05-23 Lilly Co Eli Therapeutic antibody formulation.
WO2021050563A1 (fr) * 2019-09-09 2021-03-18 The Rockefeller University Traitement par anticorps pour le tissu lésionnel de l'hidradénite suppurée
CN114401993A (zh) 2019-09-11 2022-04-26 博世健康爱尔兰有限公司 使用il-17ra抗体治疗非酒精性脂肪肝疾病(nafld)的方法
MX2022010120A (es) * 2020-02-18 2022-09-05 Amgen Inc Formulaciones de anticuerpos anti-tslp humanos y metodos de uso de los mismos.
CN111840217B (zh) * 2020-06-19 2021-04-02 北京东方百泰生物科技股份有限公司 一种抗il-17ra单克隆抗体的注射制剂
JP2024518536A (ja) * 2021-05-12 2024-05-01 アナプティスバイオ インコーポレイティッド 抗体組成物
EP4537345A1 (fr) * 2022-06-06 2025-04-16 Fusion Pharmaceuticals Inc. Méthodes de dosage d'agents thérapeutiques

Family Cites Families (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1000835A (en) 1911-06-19 1911-08-15 Stewart A Minnick Calipers.
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
IL98078A0 (en) 1991-05-07 1992-06-21 Yeda Res & Dev Pharmaceutical compositions comprising an anticytokyne
IL83878A (en) 1987-09-13 1995-07-31 Yeda Res & Dev Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
US5204244A (en) 1987-10-27 1993-04-20 Oncogen Production of chimeric antibodies by homologous recombination
GB8807803D0 (en) 1988-03-31 1988-05-05 Glaxo Group Ltd Biochemical product
KR900700134A (ko) 1988-04-15 1990-08-11 원본미기재 Il-2 수용체-특이적 키메릭 항체
IL94039A (en) 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5116964A (en) 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
ATE289350T1 (de) 1989-04-21 2005-03-15 Amgen Inc Tnf-rezeptor, tnf bindende proteine und dafür kodierende dnas
DE3922089A1 (de) 1989-05-09 1990-12-13 Basf Ag Neue proteine und ihre herstellung
DK0398327T4 (da) 1989-05-18 2013-04-15 Yeda Res & Dev Tumornekrosefaktor-bindende protein, dets oprensning og antistoffer dertil
IL95031A (en) 1989-07-18 2007-03-08 Amgen Inc Method for the production of a human recombinant tumor necrosis factor inhibitor
US5703088A (en) 1989-08-21 1997-12-30 Beth Israel Deaconess Medical Center, Inc. Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses
US5395760A (en) 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
WO1991003553A1 (fr) 1989-09-05 1991-03-21 Immunex Corporation RECEPTEURS DES FACTEURS NECROSE TUMORALE α et $g(b)
DE59010908D1 (de) 1989-09-12 2000-08-10 Hoffmann La Roche TNF-bindende Proteine
JPH03127800A (ja) 1989-10-13 1991-05-30 Teijin Ltd 腫瘍壊死因子活性抑制物質
DK0433900T3 (da) 1989-12-13 1996-01-29 Yeda Res & Dev Ekspression af rekombinant tumornekrosefaktor bindingsprotein I (TBP-I)
ATE139258T1 (de) 1990-01-12 1996-06-15 Cell Genesys Inc Erzeugung xenogener antikörper
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US5136021A (en) 1990-02-27 1992-08-04 Health Research, Inc. TNF-inhibitory protein and a method of production
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US6458360B1 (en) 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
GB2243569A (en) 1990-05-02 1991-11-06 Andrew Langdon Brush with timer
ATE309376T1 (de) 1990-06-28 2005-11-15 Hoechst Ag Fusionsproteine mit immunglobulinanteilen, ihre herstellung und verwendung
WO1992001002A1 (fr) 1990-07-11 1992-01-23 Teijin Limited Inhibiteur de l'activite du facteur de la necrose tumorale et son procede de preparation
WO1992013095A1 (fr) 1991-01-18 1992-08-06 Synergen, Inc. Procedes pour traiter les maladies induites par facteur de necrose tumorale
GEP20033082B (en) 1991-03-15 2003-10-27 Amgen Inc Pegylation of Polypeptides
IL99120A0 (en) 1991-08-07 1992-07-15 Yeda Res & Dev Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them
WO1993007863A1 (fr) 1991-10-15 1993-04-29 Mullarkey Michael F Procedes et compositions servant a traiter des reactions allergiques
US5716805A (en) 1991-10-25 1998-02-10 Immunex Corporation Methods of preparing soluble, oligomeric proteins
WO1993011161A1 (fr) 1991-11-25 1993-06-10 Enzon, Inc. Proteines multivalentes de fixation aux antigenes
CA2133326C (fr) 1992-03-30 2005-03-01 Craig A. Smith Proteines de fusion contenant un recepteur du facteur de necrose des tumeurs
JPH07509223A (ja) 1992-04-30 1995-10-12 アムジェン インコーポレイテッド インターロイキン−１媒介疾患および腫瘍壊死因子媒介疾患の治療方法
JPH05312248A (ja) 1992-05-08 1993-11-22 Nissan Motor Co Ltd シフトレバー装置
CA2123593C (fr) 1992-09-15 2000-03-14 Craig A. Smith Methode de traitement de l'inflammation dependante du tnf a l'aide d'antagonistes du facteur de necrose tumorale
AU690528B2 (en) 1992-12-04 1998-04-30 Medical Research Council Multivalent and multispecific binding proteins, their manufacture and use
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US6680057B1 (en) 1995-03-23 2004-01-20 Immunex Corporation Methods of treating autoimmune disease by administering interleukin-17 receptor
AU696775B2 (en) 1995-03-23 1998-09-17 Kirin-Amgen, Inc. IL-17 receptor
CA2227220A1 (fr) 1995-07-19 1997-02-06 Genetics Institute, Inc. Proteines humaines ctla-8 et utilisation de proteines apparentees aux proteines ctla-8
US6074849A (en) 1995-07-19 2000-06-13 Genetics Institute, Inc. Polynucleotides encoding human CTLA-8 related proteins
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
US6406867B1 (en) 1996-08-16 2002-06-18 Human Genome Sciences, Inc. Antibody to human endokine alpha and methods of use
AU7408998A (en) 1996-11-27 1998-06-22 Immunex Corporation Method of regulating nitric oxide production
JP4215172B2 (ja) 1996-12-03 2009-01-28 アムジェン フレモント インク． 複数のＶ▲下Ｈ▼およびＶ▲下κ▼領域を含むヒトＩｇ遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
EP1015488B1 (fr) 1997-09-17 2009-09-09 Human Genome Sciences, Inc. Proteine de type recepteur d'interleukine 17
US6482923B1 (en) 1997-09-17 2002-11-19 Human Genome Sciences, Inc. Interleukin 17-like receptor protein
CA2328496C (fr) 1998-05-15 2016-01-05 Genentech, Inc. Polypeptides homologues de il-17 et utilisations therapeutiques de ceux-ci
JP2000247903A (ja) * 1999-03-01 2000-09-12 Chugai Pharmaceut Co Ltd 長期安定化製剤
US6833268B1 (en) 1999-06-10 2004-12-21 Abgenix, Inc. Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
CN1245216C (zh) 1999-10-04 2006-03-15 希龙公司 稳定化的含多肽的液体药物组合物
TWI322154B (en) 2000-03-16 2010-03-21 Amgen Inc Il-17 receptor like molecules and uses thereof
EP1266002A2 (fr) 2000-03-16 2002-12-18 Amgen Inc., Molecules du type recepteur de l'interleukine 17 et leur utilisation
US20030180255A1 (en) 2000-08-24 2003-09-25 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US6793919B2 (en) 2000-10-18 2004-09-21 Immunex Corporation Methods for treating rheumatoid arthritis using IL-17 antagonists
PT1478394E (pt) 2002-02-27 2008-10-08 Immunex Corp Composição estabilizada compreendendo tnfr - fc e arginina
US20050153880A1 (en) 2002-06-27 2005-07-14 Yukio Goto Methods of treating or preventing ibd with il-18
ES2263984T3 (es) 2002-06-28 2006-12-16 Domantis Limited Ligandos doble-especificos con una vida media serica aumentada.
DE10333317A1 (de) 2003-07-22 2005-02-17 Biotecon Therapeutics Gmbh Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA)
AU2004264336B2 (en) 2003-08-05 2010-12-23 3M Innovative Properties Company Formulations containing an immune response modifier
GB0321703D0 (en) * 2003-09-16 2003-10-15 Imerys Minerals Ltd Surface modified fillers for polymer resin compositions
EP1712240B1 (fr) 2003-12-25 2015-09-09 Kyowa Hakko Kirin Co., Ltd. Preparation medicamenteuse aqueuse stable contenant un anticorps
IL159670A0 (en) 2003-12-31 2004-06-01 Yeda Res & Dev Use of il-18 binding protein in inflammations
KR20070085199A (ko) 2004-06-04 2007-08-27 디자이너 몰레큘스 인코퍼레이티드 자유-라디칼에 경화되는 폴리에스테르 및 그 사용 방법
GB0425569D0 (en) 2004-11-19 2004-12-22 Celltech R&D Ltd Biological products
WO2006088925A2 (fr) 2005-02-14 2006-08-24 Wyeth Caracterisation d'interactions de il-17f et de il-17r
EP1909831A4 (fr) 2005-06-14 2013-02-20 Amgen Inc Préparations de protéines à tamponnage spontané
BRPI0614100A2 (pt) 2005-08-03 2011-03-09 Immunogen Inc formulações de imunoconjugado lìquidas
WO2007037795A2 (fr) 2005-08-05 2007-04-05 Amgen Inc. Formulations pharmaceutiques
DE602006009834D1 (de) 2005-09-01 2009-11-26 Schering Corp Verwendung von il-23 und il-17-antagonisten zur behandlung von autoimmuner entzündlicher augenerkrankung
CA2624763A1 (fr) 2005-10-18 2007-04-26 Zymogenetics, Inc. Antagonistes de il-17c et methodes d'utilisation desdits antagonistes
HUE033949T2 (hu) 2005-11-01 2018-01-29 Wyeth Llc Nátrium klorid oldat gyógyszer újraoldására vagy hígítására
US9084777B2 (en) 2005-12-28 2015-07-21 Chugai Seiyaku Kabushiki Kaisha Stabilized antibody-containing formulations
KR20080098504A (ko) * 2006-02-03 2008-11-10 메디뮨 엘엘씨 단백질 제제
UA99716C2 (ru) * 2006-10-02 2012-09-25 Кирин-Амген Инк. Антитело, которое специфично связывает человеческий il-17 рецептор а (il-17ra)
US7833527B2 (en) 2006-10-02 2010-11-16 Amgen Inc. Methods of treating psoriasis using IL-17 Receptor A antibodies
WO2008049070A2 (fr) 2006-10-18 2008-04-24 Zymogenetics, Inc. Antagonistes de l'il-17c et leurs procédés d'utilisation
FR2910324B1 (fr) 2006-12-21 2009-03-06 Biomerieux Sa Nouveau medicament pour le traitement d'un cancer gastrique
EP2129401B8 (fr) * 2006-12-21 2020-01-15 Amgen Inc. Formulations tamponnées stables contenant des polypeptides
GB0700523D0 (en) 2007-01-11 2007-02-21 Insense Ltd The Stabilisation Of Proteins
US7790676B2 (en) 2007-03-28 2010-09-07 Zymogenetics, Inc. Soluble IL-17RA/RC fusion proteins
EP2170958A1 (fr) * 2007-06-13 2010-04-07 Amgen Inc. Complexe récepteur hétéromère de l'il-17
US20110014676A1 (en) 2007-06-29 2011-01-20 Battelle Memorial Institute Protein stabilization
EP2190476A1 (fr) 2007-08-17 2010-06-02 Amgen, Inc Formulations d'anticorps et de molécules de fusion fc à l'aide de polycations
AU2009244878B2 (en) 2008-02-21 2013-06-13 Amgen K-A, Inc. IL-17RA-IL-17RB antagonists and uses thereof
TW201117824A (en) 2009-10-12 2011-06-01 Amgen Inc Use of IL-17 receptor a antigen binding proteins
ES2753216T3 (es) 2010-01-15 2020-04-07 Amgen K A Inc Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis
EP4137514A1 (fr) 2010-10-08 2023-02-22 Novartis AG Procédés de traitement du psoriasis à l'aide des antagonistes il-17
EP3214442A1 (fr) 2010-10-25 2017-09-06 F. Hoffmann-La Roche AG Traitement de l'inflammation gastro-intestinale, du psoriasis, de l'asthme, et du psoriasis a
CN103582724A (zh) * 2011-04-07 2014-02-12 葛兰素史密斯克莱有限责任公司 粘度降低的制剂
SG193963A1 (en) * 2011-04-07 2013-11-29 Glaxosmithkline Llc Formulations with reduced viscosity
US20140234330A1 (en) 2011-07-22 2014-08-21 Amgen Inc. Il-17 receptor a is required for il-17c biology
WO2015153144A1 (fr) 2014-03-31 2015-10-08 Kirin-Amgen, Inc. Procédés de traitement du psoriasis des ongles et du cuir chevelu
JP6663910B2 (ja) 2014-08-26 2020-03-13 アムジェン ケー・エー，インコーポレイテッド 抗ＴＮＦ−α抗体療法を受けた乾癬患者を治療するための方法

Also Published As

Publication number Publication date
SI2523688T1 (en) 2018-03-30
US20130022621A1 (en) 2013-01-24
TW201129382A (en) 2011-09-01
TN2012000335A1 (en) 2013-12-12
BR112012017150B1 (pt) 2022-03-03
AU2011205402A1 (en) 2012-07-12
JP5743234B2 (ja) 2015-07-01
MX349856B (es) 2017-08-16
BR112012017150A2 (pt) 2017-10-10
WO2011088120A9 (fr) 2012-08-09
EA201891433A2 (ru) 2018-11-30
PL2523688T3 (pl) 2018-04-30
AU2017216579A1 (en) 2017-09-07
CY1122466T1 (el) 2020-10-14
AU2015202023A1 (en) 2015-05-14
EP2523688A1 (fr) 2012-11-21
PT3295957T (pt) 2019-11-12
EP2523688B1 (fr) 2017-10-11
DK3295957T3 (da) 2019-10-14
HUE046670T2 (hu) 2020-03-30
EP3632466A1 (fr) 2020-04-08
KR101766936B1 (ko) 2017-08-09
ES2652637T3 (es) 2018-02-05
EP3295957B1 (fr) 2019-08-07
SI3295957T1 (sl) 2020-02-28
UA112288C2 (uk) 2016-08-25
AU2011205402B2 (en) 2015-02-05
RS59743B1 (sr) 2020-02-28
US8883151B2 (en) 2014-11-11
DK2523688T3 (en) 2017-12-04
SG182468A1 (en) 2012-08-30
EA031209B1 (ru) 2018-12-28
NO2523688T3 (fr) 2018-03-10
CN102821787A (zh) 2012-12-12
US20150017184A1 (en) 2015-01-15
SG10201604093XA (en) 2016-07-28
TWI554282B (zh) 2016-10-21
PL3295957T3 (pl) 2020-03-31
WO2011088120A1 (fr) 2011-07-21
CO6640206A2 (es) 2013-03-22
ES2753216T3 (es) 2020-04-07
PH12012501364A1 (en) 2012-10-22
JP2015052017A (ja) 2015-03-19
PT2523688T (pt) 2018-01-05
US10072085B2 (en) 2018-09-11
US10808033B2 (en) 2020-10-20
CR20120419A (es) 2012-11-29
HRP20171939T1 (hr) 2018-03-23
EA201891433A3 (ru) 2019-02-28
US20230192873A1 (en) 2023-06-22
EA031209B9 (ru) 2021-11-19
CN102821787B (zh) 2015-07-29
KR20120118036A (ko) 2012-10-25
CA2787128A1 (fr) 2011-07-21
US20200399384A1 (en) 2020-12-24
US20180346583A1 (en) 2018-12-06
EA201290653A1 (ru) 2013-02-28
AR079903A1 (es) 2012-02-29
ZA201205167B (en) 2013-03-27
CY1119852T1 (el) 2018-06-27
JP2013517277A (ja) 2013-05-16
HUE035618T2 (en) 2018-05-28
MX2012008213A (es) 2012-11-06
RS56781B1 (sr) 2018-04-30
EP3295957A1 (fr) 2018-03-21
PE20121691A1 (es) 2012-12-14
WO2011088120A8 (fr) 2012-09-13
LT2523688T (lt) 2018-03-12
MY182680A (en) 2021-01-29
MA33989B1 (fr) 2013-02-01
US11505612B2 (en) 2022-11-22
NZ601125A (en) 2014-08-29
AU2015202023B2 (en) 2017-05-18
CA2787128C (fr) 2019-06-11
CL2012001966A1 (es) 2013-01-18
LT3295957T (lt) 2020-01-27
IL220602B (en) 2019-03-31

Similar Documents

Publication Publication Date Title
IN2012DN06720A (fr)
MX344238B (es) Compuestos de tetrazol y métodos para preparar y usar los mismos.
PH12015500940A1 (en) Bruton`s tyrosine kinase inhibitors
SG10201808102WA (en) Bicyclic heterocycle compounds and their uses in therapy
MX2014009757A (es) Derivados de isoindolina, composiciones farmaceuticas que los contienen y su uso en terapia.
IN2014DN09434A (fr)
MX2012007806A (es) Composiciones farmaceuticas para administracion oral de peptidos de insulina.
EA033374B1 (ru) Твердые фармацевтические композиции, содержащие энзалутамид, и способ лечения
IN2015DN00376A (fr)
MX392150B (es) Moduladores de receptores canabinoides.
EA201201658A1 (ru) Производные пиперидина и их применение для лечения метаболических нарушений
IL215444A0 (en) Novel p2x7r antagonists and their use
PH12012501389A1 (en) Hedgehog inhibitors
GB2523707A (en) Novel pharmaceutical formulations and their use in the treatment of periodontal disease
PH12014500250A1 (en) Substituted 3-(biphenyl-3-yl)-4 -hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one
IN2015DN03921A (fr)
UY33219A (es) Cetoenoles cíclicos para terapias
MX2013002118A (es) 2-oxi-quinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3.
GB201317815D0 (en) Oral supplementation for the reversal of human hair canities
EA201500446A1 (ru) Фармацевтическая композиция для снижения уровня n-оксида триметиламина
UA112981C2 (uk) Варіант людського gdnf
MX2013002295A (es) 1-oxo-dihidroisoquinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3.
PH12013501638A1 (en) (5s,8s)-3-(4`-chlor-3`-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one (compound a) for treatment
TR201200212A2 (tr) Risedronat içeren geliştirilmiş formülasyonlar.
TR201200215A2 (tr) Geliştirilmiş farmasötik formülasyonlar.