[go: up one dir, main page]

IN2012DN05122A - - Google Patents

Download PDF

Info

Publication number
IN2012DN05122A
IN2012DN05122A IN5122DEN2012A IN2012DN05122A IN 2012DN05122 A IN2012DN05122 A IN 2012DN05122A IN 5122DEN2012 A IN5122DEN2012 A IN 5122DEN2012A IN 2012DN05122 A IN2012DN05122 A IN 2012DN05122A
Authority
IN
India
Prior art keywords
difluoroacetonitrile
difluoroethylamine
hydrochlorides
acetates
proceeds
Prior art date
Application number
Inventor
Lui Norbert
Antons Stefan
Ahmed Moradi Wahed
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of IN2012DN05122A publication Critical patent/IN2012DN05122A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

The present invention relates to a process for preparing 2,2-difluoroethylamine of the formula (I) and salts thereof, for example sulphates, hydrochlorides or acetates, which proceeds from difluoroacetonitrile.
IN5122DEN2012 2009-12-11 2010-12-07 IN2012DN05122A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09178860 2009-12-11
US28660709P 2009-12-15 2009-12-15
PCT/EP2010/069036 WO2011069994A1 (en) 2009-12-11 2010-12-07 Method for producing 2,2-difluoroethylamine and salts thereof, starting with difluoroacetone nitrile

Publications (1)

Publication Number Publication Date
IN2012DN05122A true IN2012DN05122A (en) 2015-10-23

Family

ID=41796621

Family Applications (1)

Application Number Title Priority Date Filing Date
IN5122DEN2012 IN2012DN05122A (en) 2009-12-11 2010-12-07

Country Status (12)

Country Link
US (1) US8242311B2 (en)
EP (1) EP2509937B1 (en)
JP (1) JP5734997B2 (en)
KR (1) KR101788083B1 (en)
CN (1) CN102741218B (en)
DK (1) DK2509937T3 (en)
ES (1) ES2524304T3 (en)
IL (1) IL219711A (en)
IN (1) IN2012DN05122A (en)
MX (1) MX2012006590A (en)
TW (1) TWI482749B (en)
WO (1) WO2011069994A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2972452B1 (en) * 2011-03-09 2013-03-15 Rhodia Operations PROCESS FOR THE PREPARATION OF DIFLUOROACETONITRILE AND ITS DERIVATIVES
WO2016023773A1 (en) * 2014-08-12 2016-02-18 Basf Se Method for producing 2,2-difluoroethylamine
TWI565686B (en) * 2015-11-26 2017-01-11 南亞塑膠工業股份有限公司 Preparation method of n,n'-bis(3-aminopropyl)ethylenediamine
EP3841154B1 (en) * 2018-08-24 2022-09-21 Dow Silicones Corporation Method for condensation polymerization of hydroxyl-terminated polydiorganosiloxanes
IL305145A (en) 2021-02-17 2023-10-01 Bayer Ag A process for preparing polyfluoroalkylamines from polyfluoroalkyl alcohols
CN117430492B (en) * 2023-12-20 2024-03-22 山东国邦药业有限公司 Preparation method of difluoro acetic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2521902A (en) * 1948-04-06 1950-09-12 Eastman Kodak Co N-fluoroalkylacrylamides and polymers thereof
US4030994A (en) * 1971-06-18 1977-06-21 Merck & Co., Inc. Substitutive fluorination of organic compounds
US20090062251A1 (en) * 2007-08-17 2009-03-05 Astrazeneca Ab Novel Compounds 002
ES2438568T3 (en) * 2007-09-18 2014-01-17 Bayer Cropscience Ag Process for the preparation of 2,2-difluoroethylamine derivatives by hydrogenation of amide

Also Published As

Publication number Publication date
ES2524304T3 (en) 2014-12-05
DK2509937T3 (en) 2014-12-15
CN102741218A (en) 2012-10-17
MX2012006590A (en) 2012-10-03
US20110166388A1 (en) 2011-07-07
EP2509937A1 (en) 2012-10-17
KR20120092698A (en) 2012-08-21
TWI482749B (en) 2015-05-01
EP2509937B1 (en) 2014-10-08
CN102741218B (en) 2014-05-07
JP5734997B2 (en) 2015-06-17
IL219711A0 (en) 2012-07-31
KR101788083B1 (en) 2017-10-19
US8242311B2 (en) 2012-08-14
JP2013513566A (en) 2013-04-22
TW201130787A (en) 2011-09-16
WO2011069994A1 (en) 2011-06-16
IL219711A (en) 2014-07-31

Similar Documents

Publication Publication Date Title
IN2012DN02751A (en)
MX2012003343A (en) Process for preparing azabicyclic compounds.
MX2010007587A (en) Compounds comprising a cyclobutoxy group.
MY156274A (en) COMPOUNDS FOR THE REDUCTION OF ß-AMYLOID PRODUCTION
NZ707389A (en) Process for preparing bile acid derivatives
MY160625A (en) Process for preparing pan-cdk inhibitors of the formula(i), and intermediates in the preparation
MX2011009127A (en) Substituted nicotinamides as kcnq2/3 modulators.
UA102817C2 (en) Normal;heading 1;heading 2;heading 3;PROCESS FOR AGOMELATINE SYNTHESIS
PH12020550905A1 (en) Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives
IN2012DN05122A (en)
MX2009008660A (en) Method for the preparation of therapeutically valuable triphenylbutene derivatives.
MY151017A (en) 5-[(3,3,3-trifluoro-2-hydroxy-1-arylpropyl)amino]-1h-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents
MX2009000480A (en) Benzyl amines, a process for their production and their use as anti-inflammatory agents.
UA101091C2 (en) Method for the synthesis of ivabradine and the pharmaceutically acceptable acid addition salts thereof
MX2009009490A (en) Novel prodrugs.
IN2015DN02424A (en)
MX2010003213A (en) Novel method for the synthesis of ivabradine and the addition salts thereof with a pharmaceutically acceptable acid.
MX2012002818A (en) Novel method for synthesizing ivabradine and the addition salts thereof with a pharmaceutically acceptable acid.
MX2012007142A (en) Use of 2,3-dihydroxypropyl dodecanoate for treating seborrhea.
WO2010083996A8 (en) A process for preparing memantine
UA106988C2 (en) A method of obtaining of 1-benzyl-3-hydroxymethyl-1h-indazole and its derivatives and required intermediate magnesium compounds
NZ720106A (en) A process for the preparation of regadenoson
UA106195C2 (en) Process for the synthesis of agomelatine
MX2010003184A (en) Novel method for the synthesis of ivabradine and the addition salts thereof with a pharmaceutically acceptable acid.
TW200738704A (en) New process for the production of tiotropium salts