IN2012DN03825A - - Google Patents
Info
- Publication number
- IN2012DN03825A IN2012DN03825A IN3825DEN2012A IN2012DN03825A IN 2012DN03825 A IN2012DN03825 A IN 2012DN03825A IN 3825DEN2012 A IN3825DEN2012 A IN 3825DEN2012A IN 2012DN03825 A IN2012DN03825 A IN 2012DN03825A
- Authority
- IN
- India
- Prior art keywords
- beta
- glucosidase variants
- methods
- glucosidase
- variants
- Prior art date
Links
- 102000006995 beta-Glucosidase Human genes 0.000 abstract 5
- 108010047754 beta-Glucosidase Proteins 0.000 abstract 5
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26324009P | 2009-11-20 | 2009-11-20 | |
| PCT/US2010/057531 WO2011063308A2 (en) | 2009-11-20 | 2010-11-19 | Beta-glucosidase i variants with improved properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN03825A true IN2012DN03825A (en) | 2015-08-28 |
Family
ID=43608030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3825DEN2012 IN2012DN03825A (en) | 2009-11-20 | 2010-11-19 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9447400B2 (en) |
| EP (6) | EP2599863B1 (en) |
| JP (2) | JP2013511280A (en) |
| CN (2) | CN105316303B (en) |
| BR (1) | BR112012011711A2 (en) |
| CA (1) | CA2780767A1 (en) |
| DK (6) | DK2602317T3 (en) |
| IN (1) | IN2012DN03825A (en) |
| RU (1) | RU2012125624A (en) |
| WO (1) | WO2011063308A2 (en) |
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| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
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| JP6290626B2 (en) | 2011-03-17 | 2018-03-14 | ダニスコ・ユーエス・インク | Method for reducing viscosity in a saccharification process |
| CN102816748B (en) * | 2011-06-09 | 2014-07-16 | 中国科学院上海生命科学研究院 | Novel beta-glucosidase and coding gene and application thereof |
| JP2014527799A (en) | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | Influenza virus as a live attenuated vaccine having a mutant PB2 gene segment |
| BR112015012968A2 (en) | 2012-12-07 | 2017-09-12 | Danisco Us Inc | compositions and methods of use |
| ES2521940B1 (en) | 2013-05-10 | 2015-09-09 | Abengoa Bioenergía Nuevas Tecnologías, S.A. | Beta-glucosidase variants with reduced transglycosylation activity |
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| CN108368530A (en) * | 2015-12-10 | 2018-08-03 | 帝斯曼知识产权资产管理有限公司 | β-glucosyl enzym and application thereof |
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| WO2017143236A1 (en) | 2016-02-19 | 2017-08-24 | Yoshihiro Kawaoka | Improved influenza b virus replication for vaccine development |
| EP3336180A1 (en) | 2016-07-04 | 2018-06-20 | Evonik Degussa GmbH | Mutant alkb gene |
| WO2018053058A1 (en) | 2016-09-14 | 2018-03-22 | Danisco Us Inc. | Lignocellulosic biomass fermentation-based processes |
| EP3523415A1 (en) | 2016-10-04 | 2019-08-14 | Danisco US Inc. | Protein production in filamentous fungal cells in the absence of inducing substrates |
| WO2018106656A1 (en) | 2016-12-06 | 2018-06-14 | Danisco Us Inc | Truncated lpmo enzymes and use thereof |
| RU2771261C2 (en) | 2016-12-21 | 2022-04-29 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | Methods for application of thermostable serine proteases |
| EP3592429A1 (en) | 2017-03-06 | 2020-01-15 | DuPont Nutrition Biosciences ApS | Novel fungal fucosidases and their use in preventing and/or treating a pathogenic infection in an animal |
| CA3062660A1 (en) * | 2017-05-16 | 2018-11-22 | The Curators Of The University Of Missouri | Immobilized enzyme complexes and related methods |
| WO2019074828A1 (en) | 2017-10-09 | 2019-04-18 | Danisco Us Inc | Cellobiose dehydrogenase variants and methods of use thereof |
| JP7051491B2 (en) | 2018-02-26 | 2022-04-11 | 花王株式会社 | Mutant β-glucosidase |
| CA3093378A1 (en) | 2018-03-09 | 2019-09-12 | Danisco Us Inc | Glucoamylases and methods of use thereof |
| CN112639115A (en) | 2018-07-04 | 2021-04-09 | 丹尼斯科美国公司 | Glucoamylase and methods of use thereof |
| JP7783047B2 (en) | 2018-08-07 | 2025-12-09 | ウィスコンシン アルムニ リサーチ ファンデイション | Recombinant biologically contained filovirus vaccines |
| US11389523B2 (en) | 2018-08-20 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (HA) protein |
| WO2020097588A1 (en) | 2018-11-09 | 2020-05-14 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| AU2019384024B2 (en) | 2018-11-20 | 2026-01-08 | International N&H Denmark Aps | Engineered robust high Tm-phytase clade polypeptides and fragments thereof |
| EP3914295A2 (en) * | 2019-01-23 | 2021-12-01 | Yoshihiro Kawaoka | Mutations that confer genetic stability to additional genes in influenza viruses |
| CN113874496A (en) | 2019-02-08 | 2021-12-31 | 威斯康星校友研究基金会(Warf) | Humanized cell lines |
| US11390649B2 (en) | 2019-05-01 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication for vaccine development |
| JP7627911B2 (en) | 2019-08-27 | 2025-02-07 | ウィスコンシン アルムニ リサーチ ファンデイション | Recombinant influenza viruses with stabilized HA for replication in egg |
| JP2023511444A (en) | 2020-01-24 | 2023-03-17 | ウィスコンシン アルムニ リサーチ ファンデイション | Recombinant influenza virus with stabilized NA |
| BR112022017034A2 (en) | 2020-02-28 | 2022-12-13 | Dupont Nutrition Biosci Aps | FEED COMPOSITIONS |
| WO2021195410A1 (en) | 2020-03-25 | 2021-09-30 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| CN115478060B (en) * | 2021-06-16 | 2023-11-28 | 弈柯莱生物科技(集团)股份有限公司 | A kind of glycosyltransferase and its application |
| WO2023064905A1 (en) | 2021-10-15 | 2023-04-20 | Danisco Us Inc. | Glucoamylase variants and methods for use thereof |
| MX2024005861A (en) | 2021-11-17 | 2024-08-06 | Int N&H Denmark Aps | Improved enzymatic modification of galactolipids in food. |
| CN116426506B (en) * | 2023-03-10 | 2024-01-30 | 云南师范大学 | β-xylosidase mutant D259G with improved low-temperature activity and its application |
| CN118006590B (en) * | 2024-02-23 | 2024-12-27 | 南京师范大学常州合成生物学产业研究院有限公司 | A mutant of Microbacterium dextranolyticum β-glucosidase, method and application thereof |
| CN118956830B (en) * | 2024-09-27 | 2025-09-09 | 安徽大学 | Beta-glucosidase mutant and application thereof in hydrolyzing malonyl genistin |
| CN118853624B (en) * | 2024-09-29 | 2025-04-25 | 青岛奔月生物技术有限公司 | Glucosyltransferase mutant for catalyzing rebaudioside D to produce rebaudioside M and application thereof |
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-
2010
- 2010-11-19 CN CN201510672711.8A patent/CN105316303B/en not_active Expired - Fee Related
- 2010-11-19 DK DK12199328.1T patent/DK2602317T3/en active
- 2010-11-19 DK DK12199327.3T patent/DK2599861T3/en active
- 2010-11-19 EP EP12199330.7A patent/EP2599863B1/en not_active Not-in-force
- 2010-11-19 EP EP12199329.9A patent/EP2599862B1/en not_active Not-in-force
- 2010-11-19 IN IN3825DEN2012 patent/IN2012DN03825A/en unknown
- 2010-11-19 CA CA2780767A patent/CA2780767A1/en not_active Abandoned
- 2010-11-19 CN CN201080061975.5A patent/CN102844429B/en not_active Expired - Fee Related
- 2010-11-19 WO PCT/US2010/057531 patent/WO2011063308A2/en not_active Ceased
- 2010-11-19 DK DK10782511.9T patent/DK2501806T3/en active
- 2010-11-19 EP EP12199332.3A patent/EP2599864B1/en not_active Not-in-force
- 2010-11-19 JP JP2012540120A patent/JP2013511280A/en active Pending
- 2010-11-19 US US13/510,902 patent/US9447400B2/en not_active Expired - Fee Related
- 2010-11-19 EP EP10782511.9A patent/EP2501806B1/en not_active Not-in-force
- 2010-11-19 EP EP12199328.1A patent/EP2602317B1/en not_active Not-in-force
- 2010-11-19 BR BR112012011711A patent/BR112012011711A2/en not_active IP Right Cessation
- 2010-11-19 EP EP12199327.3A patent/EP2599861B1/en not_active Not-in-force
- 2010-11-19 RU RU2012125624/10A patent/RU2012125624A/en not_active Application Discontinuation
- 2010-11-19 DK DK12199329.9T patent/DK2599862T3/en active
- 2010-11-19 DK DK12199330.7T patent/DK2599863T3/en active
- 2010-11-19 DK DK12199332.3T patent/DK2599864T3/en active
-
2015
- 2015-06-16 JP JP2015120937A patent/JP2015211678A/en not_active Withdrawn
-
2016
- 2016-08-29 US US15/250,626 patent/US20170145396A1/en not_active Abandoned
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