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IN2012DN00551A - - Google Patents

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Publication number
IN2012DN00551A
IN2012DN00551A IN551DEN2012A IN2012DN00551A IN 2012DN00551 A IN2012DN00551 A IN 2012DN00551A IN 551DEN2012 A IN551DEN2012 A IN 551DEN2012A IN 2012DN00551 A IN2012DN00551 A IN 2012DN00551A
Authority
IN
India
Prior art keywords
radioimmunoconjugate
relates
methods
radioimmvmoconjugate
hum195
Prior art date
Application number
Other languages
English (en)
Inventor
Simon Jaime
Gaylord King A
Manuel Moreno Bermudez Josue
Original Assignee
Actinium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actinium Pharmaceuticals Inc filed Critical Actinium Pharmaceuticals Inc
Publication of IN2012DN00551A publication Critical patent/IN2012DN00551A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN551DEN2012 2009-07-22 2010-07-22 IN2012DN00551A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22771009P 2009-07-22 2009-07-22
PCT/US2010/042885 WO2011011592A1 (fr) 2009-07-22 2010-07-22 Procédés de génération de radioimmunoconjugués

Publications (1)

Publication Number Publication Date
IN2012DN00551A true IN2012DN00551A (fr) 2015-06-12

Family

ID=43499411

Family Applications (1)

Application Number Title Priority Date Filing Date
IN551DEN2012 IN2012DN00551A (fr) 2009-07-22 2010-07-22

Country Status (8)

Country Link
US (1) US9603954B2 (fr)
EP (1) EP2456472B1 (fr)
JP (2) JP5985392B2 (fr)
CN (2) CN102596258B (fr)
CA (1) CA2768658C (fr)
IN (1) IN2012DN00551A (fr)
RU (2) RU2565402C2 (fr)
WO (1) WO2011011592A1 (fr)

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US20150157742A1 (en) * 2013-12-11 2015-06-11 The European Atomic Energy Community (Euratom), Represented By The European Commission SYNTHESIS OF BIOLOGICAL COMPOUNDS LABELED WITH THE ALPHA EMITTER Ac-225
EP3142710A4 (fr) * 2014-05-16 2018-04-25 Memorial Sloan Kettering Cancer Center Marquage en une étape par actinium-225 d'anticorps pour obtenir une haute activité spécifique
US11149059B2 (en) * 2015-09-08 2021-10-19 Waters Technologies Corporation Multidimensional chromatography method for analysis of antibody-drug conjugates
US11896683B2 (en) 2016-12-16 2024-02-13 The Australian National University Radiolabelled material for targeted administration
ES2960030T3 (es) 2017-01-12 2024-02-29 Radiomedix Inc Tratamiento de células cancerosas que sobreexpresan receptores de somatostatina utilizando derivados de ocreótido quelados con radioisótopos
EP4592320A3 (fr) * 2017-07-31 2025-09-24 Actinium Pharmaceuticals, Inc. Traitements pour une malignité hématologique
CN109550061A (zh) * 2017-09-26 2019-04-02 南京江原安迪科正电子研究发展有限公司 一种用于放射性核素标记抗体的试剂盒及应用
US20230390424A1 (en) * 2020-09-11 2023-12-07 Actinium Pharmaceuticals, Inc. Trophoblast glycoprotein radioimmunotherapy for the treatment of solid cancers
US12447218B1 (en) * 2021-02-09 2025-10-21 Actinium Pharmaceuticals, Inc. Radioconjugates directed to MHC-complexed antigens in cancer
EP4490197A2 (fr) 2022-03-24 2025-01-15 Actinium Pharmaceuticals, Inc. Anticorps anti-cd45 humanisés
CA3252793A1 (fr) 2022-03-30 2025-07-07 Nihon Medi-Physics Co., Ltd. Procédé de production de complexe
CA3258344A1 (fr) 2022-06-07 2023-12-14 Actinium Pharmaceuticals, Inc. Chélateurs et conjugués bifonctionnels
CN120225566A (zh) 2022-08-22 2025-06-27 雅博得乐医疗公司 Dll3结合分子及其用途
US20250388688A1 (en) 2024-04-04 2025-12-25 Ethyreal Bio, Inc. Anti-tshr antibodies and uses thereof

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Also Published As

Publication number Publication date
EP2456472A4 (fr) 2014-08-27
CN102596258A (zh) 2012-07-18
JP2016199583A (ja) 2016-12-01
CN104710504B (zh) 2019-09-13
RU2704802C2 (ru) 2019-10-31
CN104710504A (zh) 2015-06-17
EP2456472A1 (fr) 2012-05-30
WO2011011592A1 (fr) 2011-01-27
CA2768658C (fr) 2018-04-03
EP2456472C0 (fr) 2024-03-27
EP2456472B1 (fr) 2024-03-27
JP5985392B2 (ja) 2016-09-06
RU2015137512A (ru) 2018-12-25
CN102596258B (zh) 2015-01-28
CA2768658A1 (fr) 2011-01-27
US20120220754A1 (en) 2012-08-30
HK1211304A1 (en) 2016-05-20
RU2565402C2 (ru) 2015-10-20
RU2012106301A (ru) 2013-08-27
JP2013500258A (ja) 2013-01-07
RU2015137512A3 (fr) 2019-04-02
US9603954B2 (en) 2017-03-28

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