IN2012CN00961A - - Google Patents
Info
- Publication number
- IN2012CN00961A IN2012CN00961A IN961CHN2012A IN2012CN00961A IN 2012CN00961 A IN2012CN00961 A IN 2012CN00961A IN 961CHN2012 A IN961CHN2012 A IN 961CHN2012A IN 2012CN00961 A IN2012CN00961 A IN 2012CN00961A
- Authority
- IN
- India
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167025 | 2009-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012CN00961A true IN2012CN00961A (en) | 2013-05-24 |
Family
ID=43500473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN961CHN2012 IN2012CN00961A (en) | 2009-07-31 | 2010-07-28 |
Country Status (41)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022179507A1 (en) * | 2021-02-23 | 2022-09-01 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd. | Methods of preventing, alleviating or treating tumors |
Families Citing this family (151)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3000B1 (en) | 2004-10-20 | 2016-09-05 | Genentech Inc | Antibody Formulations. |
| RU2404806C2 (en) | 2005-02-23 | 2010-11-27 | Дженентек, Инк. | Extension of time to progression of disease or lifetime of oncologic patients with application of her dimerisation inhibitors |
| CA2677108A1 (en) | 2007-03-02 | 2008-09-12 | Genentech, Inc. | Predicting response to a her inhibitor |
| TWI472339B (en) | 2008-01-30 | 2015-02-11 | Genentech Inc | Composition comprising antibody that binds to domain ii of her2 and acidic variants thereof |
| BRPI0812682A2 (en) | 2008-06-16 | 2010-06-22 | Genentech Inc | metastatic breast cancer treatment |
| EP2456789A1 (en) * | 2009-07-24 | 2012-05-30 | F. Hoffmann-La Roche AG | Optimizing the production of antibodies |
| US9345661B2 (en) | 2009-07-31 | 2016-05-24 | Genentech, Inc. | Subcutaneous anti-HER2 antibody formulations and uses thereof |
| AR078161A1 (en) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | VERY CONCENTRATED PHARMACEUTICAL FORMULATIONS OF AN ANTIBODY ANTI CD20. USE OF THE FORMULATION. TREATMENT METHOD |
| WO2011080209A2 (en) * | 2009-12-29 | 2011-07-07 | F. Hoffmann-La Roche Ag | Novel antibody formulation |
| HUE039209T2 (en) | 2011-03-31 | 2018-12-28 | Merck Sharp & Dohme | Stable formulations of antibodies to human programmed death receptor pd-1 and related treatments |
| PT4241849T (en) | 2011-10-14 | 2024-10-30 | Hoffmann La Roche | Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab |
| CA2854233C (en) | 2011-11-04 | 2020-05-12 | Zymeworks Inc. | Stable heterodimeric antibody design with mutations in the fc domain |
| AR090244A1 (en) * | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | FORMULATION OF ANTI-SELECTINE ANTIBODY P |
| US9574193B2 (en) | 2012-05-17 | 2017-02-21 | Ionis Pharmaceuticals, Inc. | Methods and compositions for modulating apolipoprotein (a) expression |
| WO2013173789A2 (en) * | 2012-05-17 | 2013-11-21 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide compositions |
| PL3427721T3 (en) | 2012-05-18 | 2025-07-14 | Genentech, Inc. | High-concentration monoclonal antibody formulations |
| LT2864346T (en) | 2012-06-21 | 2019-01-25 | Synthon Biopharmaceuticals B.V. | Method of purifying an antibody |
| WO2014052713A2 (en) | 2012-09-27 | 2014-04-03 | Massachusetts Institute Of Technology | Her2-and vegf-a-binding proteins with enhanced stability |
| KR101454646B1 (en) * | 2012-11-05 | 2014-10-27 | (주)한국비엠아이 | Stabilizer for hyaluronidase and liquid formulation comprising hyaluronidase |
| UA117466C2 (en) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | STABLE COMPOSITION IN THE VIEW OF AN ANTIBODY ANTIBODY TO IL-23p19 |
| PL2934582T3 (en) * | 2012-12-21 | 2020-08-10 | Ichnos Sciences SA | Anti her2 antibody formulation |
| CN105209069B (en) | 2013-03-13 | 2019-08-23 | 豪夫迈·罗氏有限公司 | Antibody formulation |
| KR20140119396A (en) | 2013-03-29 | 2014-10-10 | 삼성전자주식회사 | Liquid formulation containing a protein drug |
| AR095863A1 (en) | 2013-04-16 | 2015-11-18 | Genentech Inc | VARIATIONS OF PERTUZUMAB, ITS ASSESSMENT, METHOD OF TREATMENT, METHOD OF PREPARATION AND ARTICLE OF MANUFACTURE |
| IL312865B2 (en) * | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-reducing agents |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| KR102849905B1 (en) * | 2014-02-28 | 2025-08-26 | 메뤼스 엔.페. | Antibody that binds erbb-2 and erbb-3 |
| CN104906576B (en) * | 2014-03-13 | 2018-06-19 | 四川科伦博泰生物医药股份有限公司 | For hypodermic high concentration anti-VEGF antibody preparaton |
| CA2946860A1 (en) | 2014-04-25 | 2015-10-29 | Genentech, Inc. | Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab |
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| EP3851445A1 (en) | 2014-06-23 | 2021-07-21 | Novartis AG | Site specific protein modifications |
| US20170204149A1 (en) | 2014-06-23 | 2017-07-20 | Novartis Ag | Hsa-gdf-15 fusion polypeptide and use thereof |
| WO2016044334A1 (en) | 2014-09-15 | 2016-03-24 | Genentech, Inc. | Antibody formulations |
| EA037084B9 (en) | 2014-12-04 | 2021-08-05 | Янссен Байотек, Инк. | Anti-cd38 antibodies for treatment of acute myeloid leukemia |
| AR103173A1 (en) * | 2014-12-22 | 2017-04-19 | Novarits Ag | PHARMACEUTICAL PRODUCTS AND STABLE LIQUID COMPOSITIONS OF ANTIBODIES IL-17 |
| BR112017014194A2 (en) | 2015-01-23 | 2018-01-09 | Novartis Ag | synthetic apelin fatty acid conjugates with improved half life |
| US9824394B1 (en) | 2015-02-06 | 2017-11-21 | Square, Inc. | Payment processor financing of customer purchases |
| US9779432B1 (en) | 2015-03-31 | 2017-10-03 | Square, Inc. | Invoice financing and repayment |
| WO2016187546A1 (en) | 2015-05-20 | 2016-11-24 | Janssen Biotech, Inc. | Anti-cd38 antibodies for treatment of light chain amyloidosis and other cd38-positive hematological malignancies |
| FI3302551T3 (en) | 2015-05-30 | 2024-08-27 | Hoffmann La Roche | Methods of treating her2-positive previously untreated metastatic breast cancer |
| AU2016282674B2 (en) * | 2015-06-22 | 2022-01-13 | Janssen Biotech, Inc. | Combination therapies for heme malignancies with anti-CD38 antibodies and survivin inhibitors |
| WO2017003270A1 (en) * | 2015-07-02 | 2017-01-05 | 주식회사 녹십자 | Hunter syndrome therapeutic agent and treatment method |
| KR20170004814A (en) * | 2015-07-02 | 2017-01-11 | 주식회사 녹십자 | Formulation for treating hunter syndrome |
| UA124259C2 (en) * | 2015-09-28 | 2021-08-18 | Сужоу Санкадіа Байофармасьютікалз Ко., Лтд. | PHARMACEUTICAL PREPARATION OF STABLE ANTI-PD-1 ANTIBODY AND ITS USE IN MEDICINE |
| WO2017069628A2 (en) | 2015-10-23 | 2017-04-27 | Merus N.V. | Binding molecules that inhibit cancer growth |
| CA3004152C (en) | 2015-11-03 | 2024-04-16 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-cd38 antibodies and their uses |
| WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
| CN106729743B (en) | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | anti-ErbB 2 antibody-drug conjugate, and composition, preparation method and application thereof |
| US20190000923A1 (en) | 2015-12-22 | 2019-01-03 | Novartis Ag | Methods of treating or ameliorating metabolic disorders using growth differentiation factor 15 (gdf-15) |
| JP2019527678A (en) | 2016-06-28 | 2019-10-03 | ユーエムセー・ユトレヒト・ホールディング・ベー・フェー | Treatment of IgE-mediated diseases with antibodies that specifically bind to CD38 |
| PH12018502670B1 (en) | 2016-06-30 | 2023-03-24 | Celltrion Inc | Stable liquid pharmaceutical preparation |
| CR20220408A (en) | 2016-09-14 | 2022-10-20 | Teneobio Inc | Cd3 binding antibodies |
| EP3538136A1 (en) * | 2016-11-10 | 2019-09-18 | Translate Bio, Inc. | Subcutaneous delivery of messenger rna |
| BR112019012354A2 (en) | 2016-12-21 | 2019-11-26 | Teneobio Inc | anti-bcma heavy chain antibodies only |
| WO2018125589A1 (en) | 2016-12-28 | 2018-07-05 | Genentech, Inc. | Treatment of advanced her2 expressing cancer |
| SI3570884T1 (en) | 2017-01-17 | 2021-02-26 | Genentech, Inc. | Subcutaneous her2 antibody formulations |
| CN114984206A (en) | 2017-03-02 | 2022-09-02 | 基因泰克公司 | Adjunctive treatment for HER2 positive breast cancer |
| WO2018182422A1 (en) | 2017-03-31 | 2018-10-04 | Merus N.V. | Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene |
| WO2018200505A1 (en) | 2017-04-24 | 2018-11-01 | Genentech, Inc. | Erbb2/her2 mutations in the transmbrane or juxtamembrane domain |
| JP7382232B2 (en) | 2017-05-02 | 2023-11-16 | メルク・シャープ・アンド・ドーム・エルエルシー | Preparation of anti-LAG3 antibody and co-formulation of anti-LAG3 antibody and anti-PD-1 antibody |
| JOP20190260A1 (en) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | Stable formulations of programmed death receptor 1 (pd-1) antibodies and methods of use thereof |
| WO2018211517A1 (en) | 2017-05-16 | 2018-11-22 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
| JP2020521788A (en) * | 2017-06-02 | 2020-07-27 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | Route of administration of immune agonist |
| JP7240335B2 (en) | 2017-06-20 | 2023-03-15 | テネオワン， インコーポレイテッド | Anti-BCMA heavy chain only antibody |
| IL271194B2 (en) | 2017-06-20 | 2024-10-01 | Teneobio Inc | Anti-BCMA antibodies containing only heavy chains |
| CA3068167A1 (en) * | 2017-06-23 | 2018-12-27 | Anette Weyergang | Diagnosis and treatment of cancer |
| JP7407699B2 (en) * | 2017-07-28 | 2024-01-04 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | Bispecific antibody preparation |
| AU2018312816B2 (en) | 2017-08-09 | 2021-05-27 | Merus N.V. | Antibodies that bind EGFR and cMET |
| EP3681908A1 (en) | 2017-09-13 | 2020-07-22 | Teneobio, Inc. | Heavy chain antibodies binding to ectoenzymes |
| US12251474B2 (en) | 2017-09-15 | 2025-03-18 | Amgen Inc. | Process for lyophilized pharmaceutical formulations of a therapeutic protein |
| CA3079242A1 (en) | 2017-10-31 | 2019-05-09 | Janssen Biotech, Inc. | Methods of treating high risk multiple myeloma |
| CN119386161A (en) | 2017-12-22 | 2025-02-07 | 诺华股份有限公司 | Methods of treating metabolic disorders using FGF21 variants |
| CN107898756B (en) * | 2017-12-22 | 2020-11-20 | 东曜药业有限公司 | A high-concentration nimotuzumab preparation for subcutaneous or intramuscular injection and its preparation method and application |
| CN111683966B (en) | 2017-12-22 | 2023-07-11 | 特尼奥生物股份有限公司 | Heavy chain antibody that binds to CD22 |
| WO2019201894A1 (en) * | 2018-04-16 | 2019-10-24 | Merck Patent Gmbh | Additives for protein formulations to improve thermal stability |
| EP3560945A1 (en) | 2018-04-27 | 2019-10-30 | F. Hoffmann-La Roche AG | Methods for purification of polypeptides using polysorbates |
| CA3100118A1 (en) * | 2018-05-16 | 2019-11-21 | Janssen Biotech, Inc. | Bcma/cd3 and gprdc5d/cd3 bispecific antibodies for use in cancer therapy |
| CN110732023B (en) * | 2018-07-18 | 2023-06-16 | 江苏恒瑞医药股份有限公司 | HER2 antibody pharmaceutical composition and application thereof |
| KR20200010103A (en) * | 2018-07-19 | 2020-01-30 | (주)셀트리온 | Stable Liquid Pharmaceutical Formulation |
| JP7439046B2 (en) | 2018-07-20 | 2024-02-27 | テネオツー・インコーポレイテッド | Heavy chain antibody that binds to CD19 |
| EP3636752A4 (en) | 2018-07-25 | 2021-04-28 | Alteogen, Inc. | NEW HYDROLYZING ENZYME MUTANT HYALURONIC ACID AND PHARMACEUTICAL COMPOSITION CONTAINING IT |
| US20200113912A1 (en) | 2018-09-12 | 2020-04-16 | Silverback Therapeutics, Inc. | Methods and Compositions for the Treatment of Disease with Immune Stimulatory Conjugates |
| WO2020060192A1 (en) * | 2018-09-18 | 2020-03-26 | 삼성바이오에피스 주식회사 | Trastuzumab stabilizing liquid formulation containing high concentration of surfactant |
| JP2022505445A (en) | 2018-10-26 | 2022-01-14 | テネオバイオ， インコーポレイテッド | Heavy chain antibody that binds to CD38 |
| US20210388070A1 (en) * | 2018-10-30 | 2021-12-16 | Alexion Pharmaceuticals, Inc. | Co-administration of a hyaluronidase and anti-c5 antibody for treatment of complement-associated conditions |
| EP3876978A4 (en) * | 2018-11-07 | 2022-09-28 | Merck Sharp & Dohme Corp. | STABLE FORMULATIONS OF PROGRAMMED DEATH RECEPTOR 1 (MP-1) ANTIBODIES AND THEIR METHODS OF USE |
| KR20210089215A (en) | 2018-11-07 | 2021-07-15 | 머크 샤프 앤드 돔 코포레이션 | Co-Formulation of Anti-LAG3 Antibody and Anti-PD-1 Antibody |
| CN111202845A (en) * | 2018-11-22 | 2020-05-29 | 上海医药集团股份有限公司 | Pharmaceutical formulations containing anti-CD20 antibodies, methods for their preparation and applications |
| CN113396158A (en) | 2018-11-26 | 2021-09-14 | 诺华股份有限公司 | LPL-GPIHBP1 fusion polypeptide |
| EP3906061A4 (en) * | 2019-01-04 | 2023-04-05 | Actinium Pharmaceuticals, Inc. | Methods for treating cancer using combinations of parp inhibitors and antibody radioconjugates |
| US20220098252A1 (en) | 2019-01-25 | 2022-03-31 | Ospedale San Raffaele S.R.L. | Inhibitor of dux4 and uses thereof |
| CR20210435A (en) | 2019-02-18 | 2021-09-20 | Lilly Co Eli | Therapeutic antibody formulation |
| KR20230037691A (en) * | 2019-03-25 | 2023-03-16 | (주)알테오젠 | Pharmaceutical composition, comprising human hyaluronidase PH20 variant and drug, for subcutaneous injection |
| EA202192736A1 (en) | 2019-04-05 | 2022-01-27 | Тенеобио, Инк. | ANTIBODIES CONTAINING ONLY HEAVY CHAINS THAT BIND TO PSMA |
| CN110179746A (en) | 2019-05-17 | 2019-08-30 | 通化东宝生物科技有限公司 | A kind of stable Su Jin monoclonal antibody injection and preparation method thereof |
| BR112021024956A2 (en) | 2019-06-14 | 2022-01-25 | Teneobio Inc | Multispecific heavy chain antibodies that bind cd22 and cd3 |
| CA3141085A1 (en) | 2019-06-19 | 2020-12-24 | Brenda Stevens | Anti-mesothelin antibodies and immunoconjugates thereof |
| EP4004050A2 (en) | 2019-07-30 | 2022-06-01 | QLSF Biotherapeutics Inc. | Multispecific binding compound that bind to lfrrc15 and cd3 |
| AU2020325415A1 (en) * | 2019-08-07 | 2022-02-24 | Beijing Hanmi Pharmaceutical Co., Ltd. | Preparation comprising anti-PD-1/HER2 bispecific antibody, and preparation method therefor and use thereof |
| GB201913697D0 (en) | 2019-09-23 | 2019-11-06 | King S College London | DAP10/DAP12 fusion polypeptides |
| WO2021079337A1 (en) * | 2019-10-23 | 2021-04-29 | Cadila Healthcare Limited | Pharmaceutical formulation of anti-her2 antibody and preparation thereof |
| CA3159770A1 (en) | 2019-11-15 | 2021-05-20 | Seagen Inc. | Methods of treating her2 positive breast cancer with tucatinib in combination with an anti-her2 antibody-drug conjugate |
| JP2023501394A (en) * | 2019-11-15 | 2023-01-18 | エフ．ホフマン－ラ ロシュ アーゲー | Prevention of visible particle formation in aqueous protein solutions |
| WO2021096278A1 (en) * | 2019-11-15 | 2021-05-20 | 삼성바이오에피스 주식회사 | Liquid phase composition for antibody drug |
| CN114787191A (en) * | 2019-12-09 | 2022-07-22 | 基因泰克公司 | anti-PD-L1 antibody formulations |
| CU20190104A7 (en) | 2019-12-17 | 2021-08-06 | Ct Inmunologia Molecular | STABLE FORMULATION OF THE NIMOTUZUMAB ANTIBODY |
| EP4077391A1 (en) | 2019-12-18 | 2022-10-26 | Teneofour, Inc. | Heavy chain antibodies binding to cd38 |
| WO2021168274A1 (en) | 2020-02-21 | 2021-08-26 | Silverback Therapeutics, Inc. | Nectin-4 antibody conjugates and uses thereof |
| MX2022010951A (en) * | 2020-03-04 | 2022-10-07 | Shanghai Henlius Biotech Inc | Pharmaceutical formulation comprising bevacizumab. |
| GB202003277D0 (en) | 2020-03-06 | 2020-04-22 | King S College London | Therapeutic agents |
| CA3214992A1 (en) | 2020-04-29 | 2021-11-04 | Teneobio, Inc. | Multispecific heavy chain antibodies with modified heavy chain constant regions |
| US20230203161A1 (en) | 2020-04-29 | 2023-06-29 | Teneobio, Inc | Multispecific heavy chain antibodies with modified heavy chain constant regions |
| GB202007655D0 (en) | 2020-05-22 | 2020-07-08 | King S College London | Chimeric nkg2d protein |
| CN113797161A (en) * | 2020-06-11 | 2021-12-17 | 上海宝济药业有限公司 | A kind of liquid preparation of recombinant human hyaluronidase and application thereof |
| CN113827717A (en) * | 2020-06-23 | 2021-12-24 | 三生国健药业（上海）股份有限公司 | Anti-HER2 monoclonal antibody freeze-dried preparation and preparation method |
| CN113827718A (en) * | 2020-06-24 | 2021-12-24 | 上海宝济药业有限公司 | Preparation containing hyaluronidase and application thereof |
| KR20250151568A (en) | 2020-06-29 | 2025-10-21 | 제넨테크, 인크. | Pertuzumab plus trastuzumab fixed dose combination |
| AU2021300179A1 (en) | 2020-06-30 | 2023-02-02 | Teneobio, Inc. | Multi-specific antibodies binding to BCMA |
| AU2021300362A1 (en) | 2020-07-01 | 2023-02-23 | ARS Pharmaceuticals, Inc. | Anti-ASGR1 antibody conjugates and uses thereof |
| US12221638B2 (en) | 2020-08-07 | 2025-02-11 | Alteogen Inc. | Method for producing recombinant hyaluronidase |
| CA3191224A1 (en) | 2020-10-16 | 2022-04-21 | Shenda GU | Multispecific binding compounds that bind to pd-l1 |
| TW202233684A (en) | 2020-11-18 | 2022-09-01 | 美商泰尼歐生物公司 | Heavy chain antibodies binding to folate receptor alpha |
| IL303350A (en) | 2020-12-04 | 2023-08-01 | Macrogenics Inc | Preparations containing an antibody against HER2/NEU and their use |
| WO2022141232A1 (en) * | 2020-12-30 | 2022-07-07 | 上海宝济药业有限公司 | Recombinant human hyaluronidase formulation and application thereof |
| WO2022183074A2 (en) | 2021-02-25 | 2022-09-01 | Teneobio, Inc. | Anti-psma antibodies and car-t structures |
| CN116917327A (en) | 2021-02-26 | 2023-10-20 | 特尼奥生物股份有限公司 | Anti-MUC1-C antibody and CAR-T structure |
| JP2024511059A (en) | 2021-03-23 | 2024-03-12 | キングス カレッジ ロンドン | Compositions comprising NKG2D, CXCR2, and DAP10/DAP12 fusion polypeptides and methods of use thereof |
| TW202304994A (en) | 2021-04-02 | 2023-02-01 | 美商泰尼歐生物公司 | Agonistic anti-il-2r antibodies and methods of use |
| JP2024514107A (en) | 2021-04-06 | 2024-03-28 | テネオバイオ， インコーポレイテッド | Anti-CD19 antibody and CAR-T construct |
| EP4323403A1 (en) | 2021-04-16 | 2024-02-21 | Teneobio, Inc. | Anti-cd20 antibodies and car-t structures |
| WO2022271987A1 (en) | 2021-06-23 | 2022-12-29 | TeneoFour, Inc. | Anti-cd38 antibodies and epitopes of same |
| WO2023004197A1 (en) | 2021-07-23 | 2023-01-26 | Teneoten, Inc. | Heavy chain antibodies binding to hepatitis b surface antigen |
| WO2023019556A1 (en) * | 2021-08-20 | 2023-02-23 | 齐鲁制药有限公司 | High-concentration anti-her2 antibody preparation and use thereof |
| AU2022366971A1 (en) | 2021-10-14 | 2024-05-02 | Teneobio, Inc. | Mesothelin binding proteins and uses thereof |
| TW202525339A (en) * | 2022-04-22 | 2025-07-01 | 台康生技股份有限公司 | Pharmaceutical compositons containing anti-her2 antibody for subcutaneous administration |
| WO2024026358A1 (en) | 2022-07-27 | 2024-02-01 | Teneobio, Inc. | Mesothelin binding proteins and uses thereof |
| GB202214120D0 (en) | 2022-09-27 | 2022-11-09 | King S College London | Compositions comprising NKG2D, CXCR2, and DAP10/DAP12 fusion polypeptides and methods of use thereof |
| JP2025535042A (en) | 2022-10-05 | 2025-10-22 | アムジェン インコーポレイテッド | Combination therapy comprising T cell redirection therapy and an agonist anti-IL-2R antibody or fragment thereof |
| EP4389762A1 (en) | 2022-12-23 | 2024-06-26 | Ospedale San Raffaele S.r.l. | Inhibitors of dux4 activity and their use in therapy. |
| CN121079323A (en) | 2023-02-21 | 2025-12-05 | 特尼奥生物股份有限公司 | c-Kit binding protein, chimeric antigen receptor and its uses |
| WO2024220256A1 (en) | 2023-04-18 | 2024-10-24 | Qlsf Biotherapeutics, Inc. | Antibodies binding to ly6g6d |
| WO2025158306A1 (en) * | 2024-01-25 | 2025-07-31 | Intas Pharmaceuticals Ltd. | Novel high concentration phesgo formulation |
| WO2025168089A1 (en) * | 2024-02-08 | 2025-08-14 | 上海宝济药业股份有限公司 | Pharmaceutical combination for subcutaneous administration and use thereof |
| WO2025196207A1 (en) | 2024-03-20 | 2025-09-25 | King's College London | Compositions and methods for use in depleting senescent cells and treating aging |
| WO2025217101A2 (en) | 2024-04-09 | 2025-10-16 | Amgen Inc. | Agonistic anti-il-2rbg heavy‑chain antibodies |
| WO2025235357A1 (en) | 2024-05-06 | 2025-11-13 | Rondo Therapeutics, Inc. | Bispecific antibodies that bind to cd28 and nectin-4 |
| WO2025245354A1 (en) * | 2024-05-22 | 2025-11-27 | Halozyme, Inc. | Combination therapy with dupilumab and hyaluronidases |
| WO2025249934A1 (en) * | 2024-05-29 | 2025-12-04 | (주)알테오젠 | Pharmaceutical composition for subcutaneous injection, comprising growth hormone receptor antagonist and long-acting carrier |
| WO2025264972A1 (en) * | 2024-06-21 | 2025-12-26 | Apogee Therapeutics, Inc. | Antibodies that bind il-4r alpha and antibodies that bind |
| WO2025264960A1 (en) * | 2024-06-21 | 2025-12-26 | Apogee Therapeutics, Inc. | Antibodies that bind il-13 and antibodies that bind ox40l |
Family Cites Families (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4943A (en) | 1847-01-26 | Harness-buckle | ||
| US533A (en) | 1837-12-26 | Truss for hermta | ||
| US2795529A (en) | 1954-06-17 | 1957-06-11 | American Home Prod | Stabilized hyaluronidase solution containing calcium chloride |
| CU22545A1 (en) | 1994-11-18 | 1999-03-31 | Centro Inmunologia Molecular | OBTAINING A CHEMICAL AND HUMANIZED ANTIBODY AGAINST THE RECEPTOR OF THE EPIDERMAL GROWTH FACTOR FOR DIAGNOSTIC AND THERAPEUTIC USE |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| ATE97498T1 (en) | 1984-01-30 | 1993-12-15 | Imp Cancer Res Tech | IMPROVEMENTS IN GROWTH FACTORS. |
| US4943533A (en) | 1984-03-01 | 1990-07-24 | The Regents Of The University Of California | Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor |
| US5401638A (en) | 1986-06-04 | 1995-03-28 | Oncogene Science, Inc. | Detection and quantification of neu related proteins in the biological fluids of humans |
| JP3040121B2 (en) * | 1988-01-12 | 2000-05-08 | ジェネンテク，インコーポレイテッド | Methods of treating tumor cells by inhibiting growth factor receptor function |
| WO1991003489A1 (en) | 1989-09-08 | 1991-03-21 | The Johns Hopkins University | Structural alterations of the egf receptor gene in human gliomas |
| WO1991005264A1 (en) | 1989-09-29 | 1991-04-18 | Oncogenetics Partners | Detection and quantification of neu related proteins in the biological fluids of humans |
| US5945098A (en) | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
| US5721348A (en) | 1990-12-14 | 1998-02-24 | University Of Connecticut | DNA encoding PH-20 proteins |
| DE122004000008I1 (en) | 1991-06-14 | 2005-06-09 | Genentech Inc | Humanized heregulin antibody. |
| AU4025193A (en) | 1992-04-08 | 1993-11-18 | Cetus Oncology Corporation | Humanized C-erbB-2 specific antibodies |
| JPH08504172A (en) | 1992-06-30 | 1996-05-07 | オンコロジクス，インコーポレイティド | Anti-erbB-2 monoclonal antibody combination and method of use |
| DK0659439T3 (en) | 1993-12-24 | 2002-01-14 | Merck Patent Gmbh | immunoconjugates |
| ATE176910T1 (en) | 1994-07-21 | 1999-03-15 | Akzo Nobel Nv | CYCLIC KETONE PEROXIDE PREPARATIONS |
| US5804396A (en) | 1994-10-12 | 1998-09-08 | Sugen, Inc. | Assay for agents active in proliferative disorders |
| US5573186A (en) | 1995-03-20 | 1996-11-12 | Moen Incorporated | Stationary venturi diverter valve |
| ES2332984T3 (en) | 1995-03-30 | 2010-02-16 | Pfizer Products Inc. | DERIVATIVES OF QUINAZOLINAS. |
| GB9508565D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quiazoline derivative |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| CA2222231A1 (en) | 1995-06-07 | 1996-12-19 | Imclone Systems Incorporated | Antibody and antibody fragments for inhibiting the growth of tumors |
| US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| ES2434840T3 (en) * | 1995-07-27 | 2013-12-17 | Genentech, Inc. | Formulation of stable isotonic lyophilized protein |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US5783186A (en) * | 1995-12-05 | 1998-07-21 | Amgen Inc. | Antibody-induced apoptosis |
| NZ332119A (en) | 1996-04-12 | 2001-08-31 | Warner Lambert Co | Quinazoline compounds which are irreversible inhibitors of tyrosine kinases |
| EP0852951A1 (en) | 1996-11-19 | 1998-07-15 | Roche Diagnostics GmbH | Stable lyophilized monoclonal or polyclonal antibodies containing pharmaceuticals |
| UA73073C2 (en) | 1997-04-03 | 2005-06-15 | Уайт Холдінгз Корпорейшн | Substituted 3-cyan chinolines |
| US5994071A (en) | 1997-04-04 | 1999-11-30 | Albany Medical College | Assessment of prostate cancer |
| US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| US6991790B1 (en) | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
| ZA986732B (en) | 1997-07-29 | 1999-02-02 | Warner Lambert Co | Irreversible inhibitiors of tyrosine kinases |
| ZA986729B (en) | 1997-07-29 | 1999-02-02 | Warner Lambert Co | Irreversible inhibitors of tyrosine kinases |
| TW436485B (en) | 1997-08-01 | 2001-05-28 | American Cyanamid Co | Substituted quinazoline derivatives |
| ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
| CN1305896C (en) | 1998-05-06 | 2007-03-21 | 基因技术股份有限公司 | Protein purification by ion exchange chromatography |
| US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
| GEP20104998B (en) | 1999-06-25 | 2010-06-10 | Genentech Inc | Humanized antibody which binds erbb2 and blocks activation by ligand receptor of erbb2 (variants) and use of the composition comprising these antibodies methods for treating cancer |
| DE60042693D1 (en) | 1999-08-27 | 2009-09-17 | Genentech Inc | DOSAGE FOR TREATMENT WITH ANTI ERBB2 ANTIBODIES |
| US6632979B2 (en) * | 2000-03-16 | 2003-10-14 | Genentech, Inc. | Rodent HER2 tumor model |
| NZ522444A (en) | 2000-05-19 | 2004-09-24 | Genentech Inc | Gene detection assay for improving the likelihood of an effective response to an ErbB antagonist cancer therapy |
| AU2001277781A1 (en) | 2000-08-11 | 2002-02-25 | Chugai Seiyaku Kabushiki Kaisha | Stabilized antibody-containing preparations |
| PL218428B1 (en) | 2000-10-06 | 2014-12-31 | Kyowa Hakko Kogyo Kk | Cells producing antibody compositions |
| US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
| PT1324776E (en) | 2000-10-12 | 2009-12-23 | Genentech Inc | Reduced-viscosity concentrated protein formulations |
| DE10153197A1 (en) | 2001-10-27 | 2003-05-08 | Merck Patent Gmbh | Metallic gloss pigment |
| CN101721362B (en) | 2002-02-14 | 2018-07-03 | 中外制药株式会社 | Pharmaceutical solutions comprising antibody |
| TW555245U (en) | 2003-01-29 | 2003-09-21 | Hon Hai Prec Ind Co Ltd | Cable connector assembly |
| US20060104968A1 (en) | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| US7871607B2 (en) | 2003-03-05 | 2011-01-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases |
| CN1942588B (en) | 2003-03-05 | 2013-06-12 | 海洋酶公司 | Soluble hyaluronidase glycoproteins (sHASEGP), methods for their preparation, their use and pharmaceutical compositions comprising them |
| US20090123367A1 (en) * | 2003-03-05 | 2009-05-14 | Delfmems | Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases |
| EP3178492A1 (en) | 2003-04-04 | 2017-06-14 | Genentech, Inc. | High concentration antibody and protein formulations |
| US20050158303A1 (en) | 2003-04-04 | 2005-07-21 | Genentech, Inc. | Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| KR101441358B1 (en) | 2003-05-14 | 2014-09-24 | 이뮤노젠 아이엔씨 | Drug Conjugate Composition |
| US20050180952A1 (en) | 2003-08-26 | 2005-08-18 | Pettis Ronald J. | Methods for intradermal delivery of therapeutics agents |
| MXPA06004418A (en) | 2003-10-24 | 2006-07-06 | Mdc Invest Holdings Inc | Dual chamber mixing syringe and method for use. |
| AU2005249490B2 (en) * | 2004-06-01 | 2010-07-29 | Genentech, Inc. | Antibody drug conjugates and methods |
| HRP20141111T1 (en) | 2004-07-22 | 2015-01-02 | Genentech, Inc. | Her2 antibody composition |
| JO3000B1 (en) | 2004-10-20 | 2016-09-05 | Genentech Inc | Antibody Formulations. |
| BRPI0518104B8 (en) | 2005-01-21 | 2021-05-25 | Genentech Inc | industrialized article and use of her2 antibody |
| DOP2006000022A (en) | 2005-01-28 | 2006-08-15 | Wyeth Corp | STABILIZED LIQUID FORMULATIONS OF POLYPTIDES |
| RU2404806C2 (en) | 2005-02-23 | 2010-11-27 | Дженентек, Инк. | Extension of time to progression of disease or lifetime of oncologic patients with application of her dimerisation inhibitors |
| JP2006316040A (en) | 2005-05-13 | 2006-11-24 | Genentech Inc | HERCEPTIN® adjuvant therapy |
| PE20070207A1 (en) | 2005-07-22 | 2007-03-09 | Genentech Inc | COMBINED TREATMENT OF TUMORS THAT EXPRESS HER |
| US7700299B2 (en) | 2005-08-12 | 2010-04-20 | Hoffmann-La Roche Inc. | Method for predicting the response to a treatment |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| BRPI0615026A8 (en) * | 2005-08-19 | 2018-03-06 | Abbott Lab | double variable domain immunoglobulin and its uses |
| JP5231810B2 (en) | 2005-12-28 | 2013-07-10 | 中外製薬株式会社 | Antibody-containing stabilized preparation |
| TW200806317A (en) | 2006-03-20 | 2008-02-01 | Wyeth Corp | Methods for reducing protein aggregation |
| EP1998806A1 (en) | 2006-03-28 | 2008-12-10 | F. Hoffmann-Roche AG | Anti-igf-1r human monoclonal antibody formulation |
| PE20090329A1 (en) | 2007-05-30 | 2009-03-27 | Abbott Lab | HUMANIZED ANTIBODIES AGAINST GLOBULOMER AB (20-42) AND ITS USES |
| JP5070993B2 (en) | 2007-08-27 | 2012-11-14 | 富士通株式会社 | Sound processing apparatus, phase difference correction method, and computer program |
| CN101918579A (en) * | 2007-10-22 | 2010-12-15 | 先灵公司 | Fully human anti-VEGF antibodies and methods of use |
| MY171841A (en) | 2007-12-21 | 2019-11-04 | Hoffmann La Roche | Antibody formulation |
| PE20091174A1 (en) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | LIQUID FORMULATION WITH HIGH CONCENTRATION OF ANTIBODY CONTENT |
| TWI472339B (en) | 2008-01-30 | 2015-02-11 | Genentech Inc | Composition comprising antibody that binds to domain ii of her2 and acidic variants thereof |
| TWI489994B (en) * | 2008-03-17 | 2015-07-01 | Baxter Healthcare Sa | Combination and method for subcutaneous administration of immunoglobulin and hyaluronic acid |
| CN102149416B (en) | 2008-09-10 | 2014-02-12 | 弗·哈夫曼-拉罗切有限公司 | Delivery device for use with therapeutic drug |
| US7905299B2 (en) | 2008-09-18 | 2011-03-15 | Longyear Tm, Inc. | Articulation assembly for moving a drill mast |
| MX2011002402A (en) | 2008-09-19 | 2011-04-05 | Hoffmann La Roche | Novel antibody formulation. |
| US20100305500A1 (en) | 2009-05-29 | 2010-12-02 | Pacira Pharmaceuticals, Inc. | Hyaluronidase as an adjuvant for increasing the injection volume and dispersion of large diameter synthetic membrane vesicles containing a therapeutic agent |
| US9345661B2 (en) | 2009-07-31 | 2016-05-24 | Genentech, Inc. | Subcutaneous anti-HER2 antibody formulations and uses thereof |
| CA2769221A1 (en) | 2009-08-04 | 2011-02-10 | Genentech, Inc. | Concentrated polypeptide formulations with reduced viscosity |
| AR078161A1 (en) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | VERY CONCENTRATED PHARMACEUTICAL FORMULATIONS OF AN ANTIBODY ANTI CD20. USE OF THE FORMULATION. TREATMENT METHOD |
| EP3351559A3 (en) | 2010-11-08 | 2018-10-31 | F. Hoffmann-La Roche AG | Subcutaneously administered anti-il-6 receptor antibody |
| PT4241849T (en) | 2011-10-14 | 2024-10-30 | Hoffmann La Roche | Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab |
| AR095863A1 (en) | 2013-04-16 | 2015-11-18 | Genentech Inc | VARIATIONS OF PERTUZUMAB, ITS ASSESSMENT, METHOD OF TREATMENT, METHOD OF PREPARATION AND ARTICLE OF MANUFACTURE |
| SI3570884T1 (en) | 2017-01-17 | 2021-02-26 | Genentech, Inc. | Subcutaneous her2 antibody formulations |
| CN114984206A (en) | 2017-03-02 | 2022-09-02 | 基因泰克公司 | Adjunctive treatment for HER2 positive breast cancer |
| KR20230037691A (en) | 2019-03-25 | 2023-03-16 | (주)알테오젠 | Pharmaceutical composition, comprising human hyaluronidase PH20 variant and drug, for subcutaneous injection |
| KR20250151568A (en) | 2020-06-29 | 2025-10-21 | 제넨테크, 인크. | Pertuzumab plus trastuzumab fixed dose combination |
| JP2023533813A (en) | 2020-07-14 | 2023-08-04 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | Assays for Fixed Dose Formulations |
| IL315153A (en) | 2022-03-14 | 2024-10-01 | Genentech Inc | Combination therapies for breast cancer |
-
2010
- 2010-07-27 US US12/804,703 patent/US9345661B2/en active Active
- 2010-07-28 CN CN202111089810.5A patent/CN113967194A/en active Pending
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- 2010-07-28 BR BR112012002080A patent/BR112012002080A2/en not_active Application Discontinuation
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- 2010-07-28 SI SI201030218T patent/SI2459167T2/en unknown
- 2010-07-28 EA EA201200204A patent/EA027553B1/en active Protection Beyond IP Right Term
- 2010-07-28 JP JP2012522158A patent/JP5462944B2/en active Active
- 2010-07-28 MY MYPI2014002480A patent/MY172245A/en unknown
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- 2010-07-28 FI FIEP13166031.8T patent/FI2687202T3/en active
- 2010-07-28 WO PCT/EP2010/060930 patent/WO2011012637A2/en not_active Ceased
- 2010-07-28 UA UAA201201888A patent/UA102166C2/en unknown
- 2010-07-28 MX MX2013009895A patent/MX355450B/en unknown
- 2010-07-28 LT LTEP13166031.8T patent/LT2687202T/en unknown
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022179507A1 (en) * | 2021-02-23 | 2022-09-01 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd. | Methods of preventing, alleviating or treating tumors |