[go: up one dir, main page]

IL85205A0 - Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity - Google Patents

Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity

Info

Publication number
IL85205A0
IL85205A0 IL85205A IL8520588A IL85205A0 IL 85205 A0 IL85205 A0 IL 85205A0 IL 85205 A IL85205 A IL 85205A IL 8520588 A IL8520588 A IL 8520588A IL 85205 A0 IL85205 A0 IL 85205A0
Authority
IL
Israel
Prior art keywords
1beta
coli
derivatives
high level
biological activity
Prior art date
Application number
IL85205A
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL85205A0 publication Critical patent/IL85205A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL85205A 1987-01-27 1988-01-26 Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity IL85205A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US687087A 1987-01-27 1987-01-27
US07/132,185 US5047505A (en) 1987-01-27 1987-12-18 High level expression in E. coli of soluble mature HIL-1beta and derivatives with altered biological activity

Publications (1)

Publication Number Publication Date
IL85205A0 true IL85205A0 (en) 1988-07-31

Family

ID=26676180

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85205A IL85205A0 (en) 1987-01-27 1988-01-26 Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity

Country Status (8)

Country Link
US (1) US5047505A (en)
EP (1) EP0276778A3 (en)
KR (1) KR900004428B1 (en)
AU (1) AU597142B2 (en)
CA (1) CA1305080C (en)
DK (1) DK35588A (en)
IL (1) IL85205A0 (en)
NZ (1) NZ223280A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188920B1 (en) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin 1 and its derivative
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US5290917A (en) * 1988-02-03 1994-03-01 Dainippon Pharmaceutical Co., Ltd. Modified polypeptides of IL-1α
EP0352816A3 (en) * 1988-07-29 1991-03-20 Otsuka Pharmaceutical Co., Ltd. Il-1alpha derivates and medicament for treating thrombocytopenia
JPH0824595B2 (en) * 1989-02-27 1996-03-13 ニューイングランド メディカルセンター ホスピタルズ インコーポレイテッド IL-1 biological activity inhibitor
EP0570462A4 (en) * 1991-02-05 1994-11-23 Univ Maryland MODIFIED INTERLEUKIN-1BETA.
ES2105972B1 (en) * 1995-08-03 1998-06-01 Cantabria Ind Farmaceutica Sa A PROCEDURE FOR THE OBTAINING OF BIOLOGICAL RESPONSE MODIFIERS WITH RECOVERY ACTIVITY OF THE HEMATOPOYETIC FUNCTION FROM, EQUALLY AND INDISTINCATELY, TWO BACTERIAL STRAINS FIXING N2 AZOTOBACTER CHROOCOCCUM AND VINEL AZOTOBACTER.
US6626939B1 (en) * 1997-12-18 2003-09-30 Boston Scientific Scimed, Inc. Stent-graft with bioabsorbable structural support
AU2004273057C1 (en) * 2003-09-08 2011-06-30 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Non-peptide agonists and antagonists of adrenomedullin and gastrin releasing peptide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
DE3587669T2 (en) * 1984-05-18 1994-03-31 Massachusetts Inst Technology Human IL-1 cDNA sequences encoding biologically active human IL-1 proteins.
CA1341433C (en) * 1984-06-19 2003-06-24 Douglas P. Cerretti Purification of interleukin 1
DK172052B1 (en) * 1984-12-21 1997-09-29 Otsuka Pharma Co Ltd Antitumor active substance, method for its preparation, drug containing the substance, gene encoding the substance, vector containing the gene as well as recombinant microorganism transformed with such a vector
JP2591615B2 (en) * 1986-03-14 1997-03-19 大塚製薬株式会社 Interleukin-1β derivative and pharmaceutical
AU595864B2 (en) * 1986-03-14 1990-04-12 Otsuka Pharmaceutical Co., Ltd. Il-1 alpha derivatives and drugs

Also Published As

Publication number Publication date
EP0276778A3 (en) 1990-01-10
KR880009127A (en) 1988-09-14
KR900004428B1 (en) 1990-06-25
AU1076388A (en) 1988-07-28
NZ223280A (en) 1989-11-28
CA1305080C (en) 1992-07-14
EP0276778A2 (en) 1988-08-03
US5047505A (en) 1991-09-10
AU597142B2 (en) 1990-05-24
DK35588A (en) 1988-07-28
DK35588D0 (en) 1988-01-26

Similar Documents

Publication Publication Date Title
IL88182A0 (en) Derivatives of 1-desoxynojirimicyin and 1-desoxymannonojirimycin,their preparation and their use in medicaments
CY2050B1 (en) 7-Piperazinyl-or 7-morpholino-4-oxo-quinoline-3-carboxylic acid derivatives their preparation and their use as antimicrobial agents
AU5517286A (en) Antitoxin vaginal products and catamenials comprising ascorbic acid
IL91301A0 (en) Annelated tetrahydropyridine acetic acid derivatives,the preparation and use thereof
IL75979A0 (en) Propargyloxyacetonitrile derivatives,their preparation and their use in agriculture
EG19184A (en) 4-Nitro-n- phenylpyrazole derivatives and their use as pesticide
ZA885150B (en) N-aminobutyl-n-phenylarylamide derivatives,their preparation and their application in therapy
NZ226875A (en) E coli having 20% of the acetate forming ability of the wild type and its use in fermentation
IL85205A0 (en) Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity
NZ223812A (en) Morpholine derivatives and their use in agriculture and medicine
YU146189A (en) New derivatives of benzoyl urea, obtaining and use thereof
IL86028A0 (en) Novel pyrrolidine-2-(1,3-dicarbonyl)derivatives,their preparation,agents containing them,and their use
EP0310126A3 (en) Derivatives of pyrocatechol-carboxylic acid, their preparation and use as active ingredients in medicines
EP0287471A3 (en) Carboxystyrene derivatives and drugs containing them as effective ingredients
ZA899528B (en) Adenosin derivatives,their preparation and use
IL88608A0 (en) 3-hydroxy-2-(4-methoxyphenyl)-5-(2-methylaminoethyl)-2-3,dihydro-5h-1,5-benzothiazepin-4-one derivatives,their preparation and their application in therapy
GB2157684B (en) Triazolopyrimidines their preparation and use in medicine
ZA88554B (en) High level expression in e.coli of soluble mature hil-1beta and derivatives with altered biological activity
ZA888701B (en) Expression of hiv proteins in e.coli and s. cerevisiae
AR243886A1 (en) Thiophene-2-carboxamide derivatives and their pharmaceutical use
IL87022A0 (en) Hydroxyethylazole derivatives and their use as fungicides
EG18799A (en) Phenylthioureas, phenylisothioureas and phenylcarbodumides their preparation and use in the control of pests
AU4124189A (en) Novel pyridyl aminoethanols with animal growth promotion activity and a high degree of safety
EP0317649A4 (en) Novel plasmid, microbial cells, process for preparing polypeptide with oncostatic activity, and secreted polypeptide with oncostatic activity
IL85433A0 (en) Milbemycin derivatives,their preparation and their use as pesticides