IL80299A - Process for preparing netilmicin and some new selectively-blocked sisomicin derivatives for use as intermediates therein - Google Patents

Process for preparing netilmicin and some new selectively-blocked sisomicin derivatives for use as intermediates therein

Info

Publication number: IL80299A
Authority: IL; Israel
Prior art keywords: netilmicin; intermediates; preparing; blocked; sisomicin derivatives
Prior art date: 1985-10-15

Application number

IL80299A

Other versions

IL80299A0 (en

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-15

Filing date

1986-10-14

Publication date

1991-06-10

1986-10-14 Application filed by Schering Corp filed Critical Schering Corp

1987-01-30 Publication of IL80299A0 publication Critical patent/IL80299A0/en

1991-06-10 Publication of IL80299A publication Critical patent/IL80299A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL80299A 1985-10-15 1986-10-14 Process for preparing netilmicin and some new selectively-blocked sisomicin derivatives for use as intermediates therein IL80299A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US78719385A	1985-10-15	1985-10-15

Publications (2)

Publication Number	Publication Date
IL80299A0 IL80299A0 (en)	1987-01-30
IL80299A true IL80299A (en)	1991-06-10

Family

ID=25140700

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL80299A IL80299A (en)	1985-10-15	1986-10-14	Process for preparing netilmicin and some new selectively-blocked sisomicin derivatives for use as intermediates therein

Country Status (21)

Country	Link
EP (2)	EP0219093A3 (en)
JP (2)	JPH0649716B2 (en)
KR (1)	KR930003493B1 (en)
AR (1)	AR242396A1 (en)
AU (1)	AU597285B2 (en)
BG (1)	BG51252A3 (en)
CA (1)	CA1290751C (en)
DK (1)	DK169343B1 (en)
ES (1)	ES2030395T3 (en)
FI (1)	FI84486C (en)
GR (1)	GR3002670T3 (en)
HU (1)	HU199498B (en)
IE (1)	IE59481B1 (en)
IL (1)	IL80299A (en)
NZ (1)	NZ217918A (en)
PH (1)	PH24737A (en)
PL (1)	PL149511B1 (en)
PT (1)	PT83533B (en)
SU (1)	SU1630614A3 (en)
WO (1)	WO1987002365A2 (en)
ZA (1)	ZA867785B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR0139021B1 (en) *	1995-02-09	1998-04-30	김은영	1-n-ethylsisomycin preparation process
GB2478990A (en)	2010-03-26	2011-09-28	E2V Tech	Magnetron with high gfrequency cathode heater power supply
CN102796150A (en) *	2012-08-31	2012-11-28	无锡福祈制药有限公司	Method for separating and purifying high-purity sisomicin
CN105503972B (en) *	2015-12-09	2018-05-29	无锡济民可信山禾药业股份有限公司	One kind synthesizes 1-N- ethyl gentamicinCs by catalyst of heteropoly acid1aMethod
CN106866756A (en) *	2017-01-10	2017-06-20	苏利制药科技江阴有限公司	A kind of method for synthesizing 1 N Netilmicins
CN110885350A (en) *	2019-08-28	2020-03-17	山东安信制药有限公司	Preparation method of prazolmitrin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1034573A (en) *	1974-08-01	1978-07-11	Peter J.L. Daniels	Preparation of 1-n-substituted 4,6-di-(aminoglycosyl)-1,3-diaminocyclitols
US4230847A (en) *	1976-06-17	1980-10-28	Schering Corporation	Aminoglycoside antibiotic compounds
DE2712160A1 (en) *	1977-03-19	1978-09-28	Bayer Ag	PSEUDOTRISACCHARIDE, THE PROCESS FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT
DE2924659A1 (en) *	1979-06-19	1981-01-22	Bayer Ag	PSEUDOTRISACCHARIDE, THEIR PRODUCTION AND USE AS A MEDICINAL PRODUCT

1986
- 1986-10-14 PT PT83533A patent/PT83533B/en not_active IP Right Cessation
- 1986-10-14 EP EP86114196A patent/EP0219093A3/en active Pending
- 1986-10-14 CA CA000520424A patent/CA1290751C/en not_active Expired - Lifetime
- 1986-10-14 NZ NZ217918A patent/NZ217918A/en unknown
- 1986-10-14 ZA ZA867785A patent/ZA867785B/en unknown
- 1986-10-14 ES ES198686906216T patent/ES2030395T3/en not_active Expired - Lifetime
- 1986-10-14 JP JP61505496A patent/JPH0649716B2/en not_active Expired - Fee Related
- 1986-10-14 IL IL80299A patent/IL80299A/en not_active IP Right Cessation
- 1986-10-14 HU HU865468A patent/HU199498B/en not_active IP Right Cessation
- 1986-10-14 AR AR86305570A patent/AR242396A1/en active
- 1986-10-14 PL PL1986261846A patent/PL149511B1/en unknown
- 1986-10-14 AU AU64744/86A patent/AU597285B2/en not_active Ceased
- 1986-10-14 KR KR1019870700501A patent/KR930003493B1/en not_active Expired - Fee Related
- 1986-10-14 EP EP86906216A patent/EP0242385B1/en not_active Expired - Lifetime
- 1986-10-14 PH PH34364A patent/PH24737A/en unknown
- 1986-10-14 IE IE270686A patent/IE59481B1/en not_active IP Right Cessation
- 1986-10-14 WO PCT/US1986/002122 patent/WO1987002365A2/en not_active Ceased
1987
- 1987-06-12 BG BG080149A patent/BG51252A3/en unknown
- 1987-06-12 FI FI872621A patent/FI84486C/en active IP Right Grant
- 1987-06-12 DK DK299587A patent/DK169343B1/en not_active IP Right Cessation
- 1987-06-12 SU SU874202675A patent/SU1630614A3/en active
1991
- 1991-09-10 GR GR91401281T patent/GR3002670T3/en unknown
1993
- 1993-12-09 JP JP5309048A patent/JPH0735394B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FI84486C (en)	1991-12-10
ES2030395T3 (en)	1992-11-01
EP0219093A2 (en)	1987-04-22
JPH0649716B2 (en)	1994-06-29
JPH0735394B2 (en)	1995-04-19
KR930003493B1 (en)	1993-05-01
KR870700632A (en)	1987-12-30
ZA867785B (en)	1988-05-25
EP0242385A1 (en)	1987-10-28
NZ217918A (en)	1990-11-27
IE59481B1 (en)	1994-03-09
HUT43613A (en)	1987-11-30
DK299587D0 (en)	1987-06-12
EP0219093A3 (en)	1987-11-25
AU597285B2 (en)	1990-05-31
AR242396A1 (en)	1994-08-31
DK169343B1 (en)	1994-10-10
PL261846A1 (en)	1988-06-23
WO1987002365A3 (en)	1987-08-27
AU6474486A (en)	1987-05-05
PT83533A (en)	1986-11-01
EP0242385B1 (en)	1991-06-12
PT83533B (en)	1989-05-31
BG51252A3 (en)	1993-03-15
JPH06316589A (en)	1994-11-15
PL149511B1 (en)	1990-02-28
IL80299A0 (en)	1987-01-30
IE862706L (en)	1987-04-15
JPS63501079A (en)	1988-04-21
FI84486B (en)	1991-08-30
WO1987002365A2 (en)	1987-04-23
DK299587A (en)	1987-06-12
FI872621A0 (en)	1987-06-12
PH24737A (en)	1990-10-01
HU199498B (en)	1990-02-28
FI872621L (en)	1987-06-12
CA1290751C (en)	1991-10-15
GR3002670T3 (en)	1993-01-25
SU1630614A3 (en)	1991-02-23

Publication	Publication Date	Title
ZA865263B (en)	1987-03-25	Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation
GR862097B (en)	1986-12-30	Process for the preparation of urea
ZA865986B (en)	1987-06-24	Process for the preparation of urea
HUT42441A (en)	1987-07-28	Process for preparing indolyl- and indazolyl-carboxamide derivatives
HUT42500A (en)	1987-07-28	New process for preparing sphyngosine derivatives
GB2178424B (en)	1989-07-26	Process and intermediates for preparing 1a-hydroxyvitamin d compounds
GB2192888A (en)	1988-01-27	Diastereomers of 10-alkyl-10-diazaminopterins and process for preparing the same
IL80299A (en)	1991-06-10	Process for preparing netilmicin and some new selectively-blocked sisomicin derivatives for use as intermediates therein
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ZA866023B (en)	1987-03-25	New process for the preparation of sphingosine derivatives
YU218086A (en)	1988-06-30	Process for preparing herbicidically effective imidazolynones
PT81988A (en)	1986-03-01	Process for preparing novel alkylamino-furanone derivatives
EG18119A (en)	1993-06-30	Process for preparing of 1-carbacephalosporin antibiotics
HUT42432A (en)	1987-07-28	Process for preparing substituted phenyl-carbamide derivatives
GR861039B (en)	1986-08-18	Ethanobenzazepines process and intermediates for their preparation and their use as medicaments
PL249198A1 (en)	1986-02-25	Process for preparing n-phosphonmethylglycine and its derivatives
HUT42066A (en)	1987-06-29	Process for preparing 4-phenyl-propyl-indole derivatives
PT83561A (en)	1986-11-01	Process for preparing bicyclo-substituted phenylacetonitrile derivatives
EP0222210A3 (en)	1988-08-10	Process for preparing phosphoric-acid derivatives and intermediates
HUT40657A (en)	1987-01-28	Process for preparing imidazo-isoquinoline and imidazo-thieno-pyridine derivatives
YU60386A (en)	1988-08-31	Process for preparing derivatives of eburnamenine
ZA867268B (en)	1987-05-27	Process for the preparation of fish skin
PT83900B (en)	1988-06-20	Process for preparing pyrrolopyrimidine derivatives
CS564686A2 (en)	1988-08-16	Process for preparing new derivatives of avermectine

Legal Events

Date	Code	Title	Description
1996-12-05	KB	Patent renewed
2006-12-27	EXP	Patent expired