IL80184A0 - Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL80184A0
Authority: IL; Israel
Prior art keywords: alkylquinazolin; diones; piperazinyl; phenyl; substituted
Prior art date: 1985-09-30

Application number

IL80184A

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-30

Filing date

1986-09-29

Publication date

1986-12-31

1986-09-29 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1986-12-31 Publication of IL80184A0 publication Critical patent/IL80184A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL80184A 1985-09-30 1986-09-29 Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them IL80184A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/782,241 US4711883A (en)	1985-09-30	1985-09-30	Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use

Publications (1)

Publication Number	Publication Date
IL80184A0 true IL80184A0 (en)	1986-12-31

Family

ID=25125457

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL80184A IL80184A0 (en)	1985-09-30	1986-09-29	Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country	Link
US (1)	US4711883A (en)
EP (1)	EP0219259A3 (en)
JP (1)	JPS62111970A (en)
KR (1)	KR870003098A (en)
AU (1)	AU583949B2 (en)
CA (1)	CA1290334C (en)
DK (3)	DK162988C (en)
ES (1)	ES2001809A6 (en)
FI (1)	FI863910A7 (en)
GR (1)	GR862452B (en)
HU (1)	HUT43590A (en)
IL (1)	IL80184A0 (en)
NO (1)	NO863870L (en)
PT (1)	PT83458B (en)
ZA (1)	ZA867424B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL90879A0 (en) *	1988-09-02	1990-02-09	Janssen Pharmaceutica Nv	3-piperidinyl-indazole derivatives,their preparation and antihypertensive compositions containing them
PL166839B1 (en) *	1990-04-24	1995-06-30	Dresden Arzneimittel	Method of obtaining novel 3-(mercaptoalkyl)-quinazolino-(1h,3h)-diones-2,4
IE913473A1 (en) *	1990-10-15	1992-04-22	Fujisawa Pharmaceutical Co	Quinazoline derivatives and their preparation
KR100817538B1 (en) *	2006-07-05	2008-03-27	한국화학연구원	Newly substituted 1H-quinazolin-2,4-dione derivatives, preparation method thereof and pharmaceutical composition containing the same
WO2010099503A1 (en)	2009-02-26	2010-09-02	Reviva Pharmaceuticals, Inc.	Compositions, synthesis, and methods of utilizing quinazolinedione derivatives
WO2016023826A1 (en) *	2014-08-11	2016-02-18	Hydra Biosciences, Inc.	Quinazoline-2,4(1h,3h)-dione derivatives as trcp5 modulators for the treatment of neuropsychiatry disorders
CN111848528B (en) *	2019-04-29	2022-03-11	北京嘉林药业股份有限公司	Compound for preventing and/or treating cancer and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU612466A (en) *	1966-05-26	1967-11-30	Miles Laboratories Inc. V	Product and process
US3819630A (en) *	1972-08-21	1974-06-25	R Parcell	3-(1-piperazinylalkyl)-2,4-quinazolinedione compounds and methods for their production
JPS58159480A (en) *	1982-03-17	1983-09-21	Chugai Pharmaceut Co Ltd	Novel phenylpiperazine derivative
US4639518A (en) *	1984-09-24	1987-01-27	Ortho Pharmaceutical Corporation	Substituted quinazolinediones

1985
- 1985-09-30 US US06/782,241 patent/US4711883A/en not_active Expired - Lifetime
1986
- 1986-09-26 GR GR862452A patent/GR862452B/en unknown
- 1986-09-27 KR KR1019860008112A patent/KR870003098A/en not_active Withdrawn
- 1986-09-29 JP JP61228509A patent/JPS62111970A/en active Pending
- 1986-09-29 EP EP86307447A patent/EP0219259A3/en not_active Ceased
- 1986-09-29 NO NO863870A patent/NO863870L/en unknown
- 1986-09-29 IL IL80184A patent/IL80184A0/en unknown
- 1986-09-29 ZA ZA867424A patent/ZA867424B/en unknown
- 1986-09-29 CA CA000519319A patent/CA1290334C/en not_active Expired - Lifetime
- 1986-09-29 ES ES8602281A patent/ES2001809A6/en not_active Expired
- 1986-09-29 HU HU864130A patent/HUT43590A/en unknown
- 1986-09-29 DK DK465086A patent/DK162988C/en active
- 1986-09-29 AU AU63211/86A patent/AU583949B2/en not_active Ceased
- 1986-09-29 FI FI863910A patent/FI863910A7/en not_active IP Right Cessation
- 1986-09-29 PT PT83458A patent/PT83458B/en unknown
1991
- 1991-06-10 DK DK109891A patent/DK109891A/en not_active Application Discontinuation
- 1991-06-13 DK DK911135A patent/DK113591D0/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2001809A6 (en)	1988-06-16
DK113591A (en)	1991-06-13
AU6321186A (en)	1987-04-02
PT83458B (en)	1988-10-31
DK162988B (en)	1992-01-06
AU583949B2 (en)	1989-05-11
EP0219259A3 (en)	1988-01-20
DK465086A (en)	1987-03-31
EP0219259A2 (en)	1987-04-22
DK109891D0 (en)	1991-06-10
ZA867424B (en)	1988-04-27
FI863910L (en)	1987-03-31
GR862452B (en)	1987-01-27
KR870003098A (en)	1987-04-15
JPS62111970A (en)	1987-05-22
NO863870D0 (en)	1986-09-29
FI863910A7 (en)	1987-03-31
DK109891A (en)	1991-06-10
HUT43590A (en)	1987-11-30
NO863870L (en)	1987-03-31
DK113591D0 (en)	1991-06-13
PT83458A (en)	1986-10-01
US4711883A (en)	1987-12-08
DK162988C (en)	1992-06-01
DK465086D0 (en)	1986-09-29
FI863910A0 (en)	1986-09-29
CA1290334C (en)	1991-10-08

Similar Documents

Publication	Publication Date	Title
IL75986A (en)	1989-02-28	3-(2-dimethylamino)ethyl)-n-methyl-1h-indole-5-methanesulphonamide,its preparation and pharmaceutical compositions containing it
IL85989A (en)	1993-08-18	Leukotriene antagonistic polysubstituted acylphenols, their preparation, pharmaceutical compositions containing them and some intermediates therefor
IL78970A (en)	1990-06-10	3-(heteroaralkylamino-alkyl)-3-benzazepin-2-one derivatives,their preparation and pharmaceutical compositions containing them
IL74018A (en)	1988-08-31	4-((bicyclic heterocyclyl)-methyl and-hetero)-piperidines,their preparation and pharmaceutical compositions containing them
EP0163550A3 (en)	1987-05-20	New mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them
IL81790A0 (en)	1987-10-20	Hydroxylamine derivatives,their manufacture and pharmaceutical compositions containing them
NZ213113A (en)	1989-01-27	Substituted benzimidazoles, intermediates, and pharmaceutical compositions
IL76675A0 (en)	1986-02-28	Piperidine derivatives,their preparation and pharmaceutical compositions containing them
IL80339A (en)	1993-06-10	2-(2-(2-pyridyl)- phenylsulphinyl) -benzimidazoles, their preparation and pharmaceutical compositions containing them
IL65097A0 (en)	1982-04-30	N-(4-(indolyl)-piperidino-alkyl)-benzimidazolones,their preparation and pharmaceutical compositions containing them
IL80184A0 (en)	1986-12-31	Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them
NZ221633A (en)	1990-03-27	Heterocyclic sulphonamides, intermediates therefor and pharmaceutical compositions
IL79181A0 (en)	1986-09-30	3-(substituted)propenylaminothiazolylcephalosporanic acids and esters thereof,their preparation and pharmaceutical compositions containing them
IL68710A0 (en)	1983-09-30	2-(1h)-pyridinone derivatives,their preparation and pharmaceutical compositions containing them
IL75981A0 (en)	1985-12-31	4-(isoxazolyl)-thiazole-2-oxamic acid derivatives,their preparation and pharmaceutical compositions containing them
GB2159817B (en)	1987-12-31	Preparation of amidohydroxycephams, novel aminoacyloxycephams and derivatives thereof
IL76312A (en)	1991-06-10	Xenocoumacins and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL62970A (en)	1985-01-31	Substituted phenoxy-aminopropanol derivatives and intermediates therefor,their preparation and pharmaceutical compositions containing them
NZ220347A (en)	1990-05-28	Triazole derivatives, pharmaceutical compositions and intermediates
IL82614A0 (en)	1987-11-30	3-(hydroxymethyl)-isoquinoline derivatives,their preparation and pharmaceutical compositions containing them
DE3569526D1 (en)	1989-05-24	Glutarimide derivatives, their preparation and pharmaceutical compositions containing them
IL60593A (en)	1984-03-30	4-(naphthalenyloxy)piperidine derivatives,their preparation and pharmaceutical compositions containing some of same
IL53674A (en)	1981-10-30	3-(4-phenylpiperazinyl or 4-phenylpiperidyl) o-propyloximes,their preparation and pharmaceutical compositions comprising them
IL71723A (en)	1987-10-30	4-(alkanoylaminophenyl)-2-oxo-thiazolidine 4-carboxylates,their preparation and pharmaceutical compositions comprising them
IL65512A0 (en)	1982-07-30	3-(2-(3-alkyl and alkenyl-4-piperidyl)-ethyl)-indoles,their preparation and pharmaceutical compositions containing them