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IL75386A0 - 1-(bis-(4-fluorophenyl)-methyl)-4-(3-phenyl-2-propenyl)-hexahydro-1h-1,4-diazepine with calcium antagonistic activity,its preparation and compositions containing it - Google Patents

1-(bis-(4-fluorophenyl)-methyl)-4-(3-phenyl-2-propenyl)-hexahydro-1h-1,4-diazepine with calcium antagonistic activity,its preparation and compositions containing it

Info

Publication number
IL75386A0
IL75386A0 IL75386A IL7538685A IL75386A0 IL 75386 A0 IL75386 A0 IL 75386A0 IL 75386 A IL75386 A IL 75386A IL 7538685 A IL7538685 A IL 7538685A IL 75386 A0 IL75386 A0 IL 75386A0
Authority
IL
Israel
Prior art keywords
diazepine
hexahydro
propenyl
fluorophenyl
bis
Prior art date
Application number
IL75386A
Other languages
English (en)
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of IL75386A0 publication Critical patent/IL75386A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL75386A 1984-06-19 1985-06-03 1-(bis-(4-fluorophenyl)-methyl)-4-(3-phenyl-2-propenyl)-hexahydro-1h-1,4-diazepine with calcium antagonistic activity,its preparation and compositions containing it IL75386A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21471/84A IT1196150B (it) 1984-06-19 1984-06-19 Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono

Publications (1)

Publication Number Publication Date
IL75386A0 true IL75386A0 (en) 1985-10-31

Family

ID=11182299

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75386A IL75386A0 (en) 1984-06-19 1985-06-03 1-(bis-(4-fluorophenyl)-methyl)-4-(3-phenyl-2-propenyl)-hexahydro-1h-1,4-diazepine with calcium antagonistic activity,its preparation and compositions containing it

Country Status (8)

Country Link
EP (1) EP0166302A3 (xx)
JP (1) JPS6117574A (xx)
KR (1) KR860000269A (xx)
DE (1) DE166302T1 (xx)
ES (1) ES8609277A1 (xx)
FI (1) FI852423A7 (xx)
IL (1) IL75386A0 (xx)
IT (1) IT1196150B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9504662D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
EP0914319B1 (en) 1996-05-20 2001-11-21 Teijin Limited Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
AR035974A1 (es) 2001-05-18 2004-07-28 Astrazeneca Ab Derivados de diarilmetil piperazina, procesos para su preparacion, uso de estos derivados para la elaboracion de medicamentos y composicion farmaceutica
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
HRP20120343T1 (hr) 2004-08-02 2012-05-31 Astrazeneca Ab Derivati diarilmetil piperazina, njihovi pripravci i njihova uporaba

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790971A (fr) * 1971-11-09 1973-05-07 Janssen Pharmaceutica Nv Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen

Also Published As

Publication number Publication date
IT8421471A0 (it) 1984-06-19
EP0166302A2 (en) 1986-01-02
DE166302T1 (de) 1986-05-22
ES544299A0 (es) 1986-09-01
IT1196150B (it) 1988-11-10
KR860000269A (ko) 1986-01-27
EP0166302A3 (en) 1986-03-26
FI852423L (fi) 1985-12-20
FI852423A7 (fi) 1985-12-20
IT8421471A1 (it) 1985-12-19
ES8609277A1 (es) 1986-09-01
JPS6117574A (ja) 1986-01-25
FI852423A0 (fi) 1985-06-18

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