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IL197926A0 - A stable composition comprising a bone anabolic protein, namely a pthrp analogue, and uses thereof - Google Patents

A stable composition comprising a bone anabolic protein, namely a pthrp analogue, and uses thereof

Info

Publication number
IL197926A0
IL197926A0 IL197926A IL19792609A IL197926A0 IL 197926 A0 IL197926 A0 IL 197926A0 IL 197926 A IL197926 A IL 197926A IL 19792609 A IL19792609 A IL 19792609A IL 197926 A0 IL197926 A0 IL 197926A0
Authority
IL
Israel
Prior art keywords
namely
stable composition
bone anabolic
pthrp analogue
anabolic protein
Prior art date
Application number
IL197926A
Other versions
IL197926A (en
Original Assignee
Ipsen Pharma Sas
Radius Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39430237&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL197926(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ipsen Pharma Sas, Radius Health Inc filed Critical Ipsen Pharma Sas
Publication of IL197926A0 publication Critical patent/IL197926A0/en
Publication of IL197926A publication Critical patent/IL197926A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
IL197926A 2006-10-03 2007-10-03 Stable composition comprising a bone anabolic protein, namely a pthrp analogue, and uses thereof IL197926A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84896006P 2006-10-03 2006-10-03
PCT/US2007/021216 WO2008063279A2 (en) 2006-10-03 2007-10-03 A stable composition comprising a bone anabolic protein, namely a pthrp analogue, and uses thereof

Publications (2)

Publication Number Publication Date
IL197926A0 true IL197926A0 (en) 2011-08-01
IL197926A IL197926A (en) 2014-08-31

Family

ID=39430237

Family Applications (1)

Application Number Title Priority Date Filing Date
IL197926A IL197926A (en) 2006-10-03 2007-10-03 Stable composition comprising a bone anabolic protein, namely a pthrp analogue, and uses thereof

Country Status (28)

Country Link
US (1) US8148333B2 (en)
EP (2) EP2073789B8 (en)
JP (1) JP5375611B2 (en)
KR (4) KR20150020289A (en)
CN (2) CN101578093B (en)
AU (1) AU2007322334B2 (en)
BR (2) BRPI0719821B8 (en)
CA (1) CA2664734C (en)
CY (1) CY1119198T1 (en)
DK (2) DK2957278T3 (en)
ES (2) ES2739459T3 (en)
FR (1) FR23C1024I2 (en)
HR (1) HRP20171217T1 (en)
IL (1) IL197926A (en)
LT (1) LT2957278T (en)
LU (1) LUC00309I2 (en)
MX (1) MX2009003569A (en)
NL (1) NL301235I2 (en)
NO (1) NO344885B1 (en)
NZ (1) NZ576682A (en)
PL (1) PL2957278T3 (en)
PT (2) PT2957278T (en)
RS (1) RS56164B1 (en)
RU (1) RU2506070C2 (en)
SG (1) SG175580A1 (en)
SI (1) SI2957278T1 (en)
UA (1) UA98776C2 (en)
WO (1) WO2008063279A2 (en)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
LT2957278T (en) 2006-10-03 2017-09-11 Radius Health, Inc. A stable composition comprising pthrp and uses thereof
USRE49444E1 (en) 2006-10-03 2023-03-07 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
US7803770B2 (en) * 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
EP3106159A1 (en) 2010-05-12 2016-12-21 Radius Health, Inc. Therapeutic regimens
JP5965909B2 (en) 2010-09-28 2016-08-10 ラジウス ヘルス,インコーポレイテッド Selective androgen receptor modulator
EP2472328B1 (en) 2010-12-31 2013-06-19 Rohm and Haas Electronic Materials LLC Coating compositions for use with an overcoated photoresist
EP2472329B1 (en) 2010-12-31 2013-06-05 Rohm and Haas Electronic Materials LLC Coating compositions for use with an overcoated photoresist
EP2699252B1 (en) 2011-04-22 2017-10-25 Radius Health, Inc. Method of drug delivery for pth, pthrp and related peptides
KR20150116467A (en) * 2011-06-07 2015-10-15 아사히 가세이 파마 가부시키가이샤 Freeze-dried preparation containing high-purity pth and method for producing same
CA2857501C (en) 2011-11-30 2020-06-23 3M Innovative Properties Company Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same
CA2943611A1 (en) 2014-03-28 2015-10-01 Duke University Method of treating cancer using selective estrogen receptor modulators
WO2016141250A1 (en) * 2015-03-03 2016-09-09 Radius Health, Inc. USES OF PTHrP ANALOGUE IN REDUCING FRACTURE RISK
CA2984357A1 (en) 2015-04-29 2016-11-03 Radius Pharmaceuticals, Inc. Methods for treating cancer
US20180161401A1 (en) * 2015-07-06 2018-06-14 Zheng Xin Dong Novel Formulations of PTHrP Analogue
JP6525376B2 (en) 2015-08-31 2019-06-05 ローム アンド ハース エレクトロニック マテリアルズ エルエルシーRohm and Haas Electronic Materials LLC Coating composition for use with an overcoated photoresist
HUE055658T2 (en) * 2015-10-09 2021-12-28 Radius Health Inc Formulations containing PTHRP analogs, transdermal patches containing them and their use
EP3481414B1 (en) 2016-04-18 2021-11-03 Radius Health, Inc. Formulations of abaloparatide, transdermal patches thereof, and uses thereof
CA3027563C (en) 2016-06-22 2024-07-02 Ellipses Pharma Ltd Ar+ breast cancer treatment methods
EP3548012A4 (en) * 2016-11-30 2020-07-22 Purdue Research Foundation Fracture-directed bone regeneration by stimulating the parathyroid hormone receptor
JP7481115B2 (en) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ,インコーポレイテッド Polymorphic forms of RAD1901-2HCL
US10996208B2 (en) 2017-04-28 2021-05-04 Radius Health, Inc. Abaloparatide formulations and methods of testing, storing, modifying, and using same
WO2019175173A1 (en) * 2018-03-12 2019-09-19 Fresenius Kabi Ipsum S.R.L. Process for the manufacture of pthrp analogue
WO2019232283A1 (en) 2018-05-30 2019-12-05 Purdue Research Foundation Targeting anabolic drugs for accelerated fracture repair
IL279853B2 (en) 2018-07-04 2025-01-01 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
CN119390714A (en) 2019-02-12 2025-02-07 雷迪厄斯制药公司 Methods and compounds
EP4110371A1 (en) 2020-01-24 2023-01-04 Radius Health, Inc. Methods of stimulating bone growth with abalopartide and denosumab
WO2023281447A1 (en) 2021-07-07 2023-01-12 Radius Health, Inc. Methods of treating a cardiovascular ischemic event

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US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5977070A (en) * 1992-07-14 1999-11-02 Piazza; Christin Teresa Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
US5821225A (en) 1992-07-14 1998-10-13 Syntex (U.S.A.) Inc. Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
ES2179831T3 (en) 1992-09-29 2003-02-01 Inhale Therapeutic Syst RELEASE IN THE LUNGS OF ACTIVE FRAGMENTS OF PARTIROIDIAN HORMONE.
WO1995002610A1 (en) 1993-07-13 1995-01-26 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US7410948B2 (en) * 1995-07-13 2008-08-12 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Analogs of parathyroid hormone
US6544949B1 (en) * 1995-07-13 2003-04-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Analogs of parathyroid hormone
US5955574A (en) * 1995-07-13 1999-09-21 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. Analogs of parathyroid hormone
US5969095A (en) * 1995-07-13 1999-10-19 Biomeasure, Inc. Analogs of parathyroid hormone
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US7799757B2 (en) 2002-06-13 2010-09-21 Michael Chorev Analogs of parathyroid hormone and PTH-related protein as bone anabolic agents
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US7803770B2 (en) 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
LT2957278T (en) 2006-10-03 2017-09-11 Radius Health, Inc. A stable composition comprising pthrp and uses thereof

Also Published As

Publication number Publication date
LUC00309I2 (en) 2025-09-22
JP5375611B2 (en) 2013-12-25
UA98776C2 (en) 2012-06-25
CA2664734A1 (en) 2008-05-29
FR23C1024I1 (en) 2023-07-21
PL2957278T3 (en) 2017-10-31
JP2010505835A (en) 2010-02-25
SG175580A1 (en) 2011-11-28
EP2957278B1 (en) 2017-05-17
KR20090083350A (en) 2009-08-03
WO2008063279A9 (en) 2008-07-10
PT2957278T (en) 2017-08-23
CN102274492B (en) 2014-11-26
RU2506070C2 (en) 2014-02-10
EP2957278A1 (en) 2015-12-23
HK1214181A1 (en) 2016-07-22
US8148333B2 (en) 2012-04-03
BRPI0719821A2 (en) 2013-05-07
NO344885B1 (en) 2020-06-15
BRPI0719821B1 (en) 2020-04-14
EP2073789A2 (en) 2009-07-01
CN101578093B (en) 2011-09-14
BRPI0722428A2 (en) 2013-11-26
DK2957278T3 (en) 2017-07-31
MX2009003569A (en) 2009-08-25
EP2073789B8 (en) 2023-02-08
NZ576682A (en) 2012-08-31
PT2073789T (en) 2019-07-31
BRPI0719821B8 (en) 2021-05-25
RS56164B1 (en) 2017-11-30
EP2073789B1 (en) 2019-05-22
KR20150020289A (en) 2015-02-25
HRP20171217T1 (en) 2017-10-20
SI2957278T1 (en) 2017-09-29
IL197926A (en) 2014-08-31
US20100029556A1 (en) 2010-02-04
WO2008063279A3 (en) 2009-06-25
RU2009116531A (en) 2010-11-10
AU2007322334B2 (en) 2011-12-22
AU2007322334A1 (en) 2008-05-29
CN101578093A (en) 2009-11-11
KR20170067906A (en) 2017-06-16
FR23C1024I2 (en) 2024-06-14
KR101512377B1 (en) 2015-04-28
WO2008063279A2 (en) 2008-05-29
NO20091545L (en) 2009-05-27
DK2073789T3 (en) 2019-08-05
CN102274492A (en) 2011-12-14
LT2957278T (en) 2017-09-11
KR20180117738A (en) 2018-10-29
NL301235I2 (en) 2023-08-31
CA2664734C (en) 2023-08-01
ES2637283T3 (en) 2017-10-11
CY1119198T1 (en) 2018-02-14
ES2739459T3 (en) 2020-01-31

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