IL174524A0 - Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer - Google Patents
Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancerInfo
- Publication number
- IL174524A0 IL174524A0 IL174524A IL17452406A IL174524A0 IL 174524 A0 IL174524 A0 IL 174524A0 IL 174524 A IL174524 A IL 174524A IL 17452406 A IL17452406 A IL 17452406A IL 174524 A0 IL174524 A0 IL 174524A0
- Authority
- IL
- Israel
- Prior art keywords
- cancer
- treatment
- production
- bengamide derivatives
- bengamide
- Prior art date
Links
- GPVKLYONJSSZFL-UHFFFAOYSA-N NSC 750259 Natural products CCC(C)C=CC(O)C(O)C(O)C(OC)C(=O)NC1CCCCNC1=O GPVKLYONJSSZFL-UHFFFAOYSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 229930195545 bengamide Natural products 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C07D223/10—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10349669A DE10349669B3 (en) | 2003-10-24 | 2003-10-24 | Bengamide derivatives, process for their preparation and their use |
| PCT/EP2004/011244 WO2005044803A1 (en) | 2003-10-24 | 2004-10-08 | Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL174524A0 true IL174524A0 (en) | 2006-08-01 |
| IL174524A IL174524A (en) | 2012-08-30 |
Family
ID=34484998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL174524A IL174524A (en) | 2003-10-24 | 2006-03-23 | Bengamide derivatives and pharmaceutical compositions comprising them |
Country Status (29)
| Country | Link |
|---|---|
| EP (2) | EP1873146B1 (en) |
| JP (1) | JP4769190B2 (en) |
| KR (1) | KR20060120044A (en) |
| CN (2) | CN101294173A (en) |
| AR (1) | AR046553A1 (en) |
| AT (2) | ATE420074T1 (en) |
| AU (1) | AU2004287561B2 (en) |
| BR (1) | BRPI0415529A (en) |
| CA (1) | CA2543003A1 (en) |
| CL (1) | CL2009000674A1 (en) |
| CY (1) | CY1110458T1 (en) |
| DE (3) | DE10349669B3 (en) |
| DK (1) | DK1680405T3 (en) |
| ES (1) | ES2320894T3 (en) |
| HR (1) | HRP20090187T1 (en) |
| IL (1) | IL174524A (en) |
| MA (1) | MA28213A1 (en) |
| ME (1) | MEP33108A (en) |
| MX (1) | MXPA06004084A (en) |
| NO (1) | NO20062149L (en) |
| NZ (1) | NZ546744A (en) |
| PL (1) | PL1680405T3 (en) |
| PT (1) | PT1680405E (en) |
| RS (1) | RS20060263A (en) |
| RU (1) | RU2357956C2 (en) |
| SI (1) | SI1680405T1 (en) |
| UY (1) | UY28574A1 (en) |
| WO (1) | WO2005044803A1 (en) |
| ZA (1) | ZA200602231B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2878528B1 (en) | 2004-11-29 | 2008-05-16 | Aventis Pharma Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
| FR2878525B1 (en) * | 2004-11-29 | 2007-02-23 | Aventis Pharma Sa | BENGAMIDES HAVING SUBSTITUTED CAPROLACTAM CYCLE, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
| FR2901554B1 (en) | 2006-05-24 | 2011-04-01 | Sanofi Aventis | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZAZEPINE, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
| FR2901556A1 (en) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE DERIVATIVES, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
| FR2901555A1 (en) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZOTHIAZEPINE, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU208121B (en) * | 1986-04-04 | 1993-08-30 | Sankyo Co | Process for producing perhydrothiazepine and perhydroazepine derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
| CO5140099A1 (en) * | 1998-11-17 | 2002-03-22 | Novartis Ag | CERTAIN SUBSTITUTED CAPROLACTAMAS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND ITS USE IN TUMORS TREATMENT |
| CN1191237C (en) * | 2000-05-11 | 2005-03-02 | 诺瓦提斯公司 | Substituted caprolactam carbonates and ethers and their use as antineoplastic agents |
| JP2004262793A (en) * | 2003-02-28 | 2004-09-24 | Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai | Compound N-9011, production method and use thereof |
| BRPI0412843A (en) * | 2003-07-25 | 2006-09-26 | Novartis Ag | substituted lactams and their use as anticancer agents |
-
2003
- 2003-10-24 DE DE10349669A patent/DE10349669B3/en not_active Expired - Fee Related
-
2004
- 2004-10-08 AT AT04765884T patent/ATE420074T1/en active
- 2004-10-08 PL PL04765884T patent/PL1680405T3/en unknown
- 2004-10-08 DE DE502004011536T patent/DE502004011536D1/en not_active Expired - Lifetime
- 2004-10-08 DE DE502004008837T patent/DE502004008837D1/en not_active Expired - Lifetime
- 2004-10-08 RS YUP-2006/0263A patent/RS20060263A/en unknown
- 2004-10-08 ES ES04765884T patent/ES2320894T3/en not_active Expired - Lifetime
- 2004-10-08 AT AT07007021T patent/ATE477244T1/en not_active IP Right Cessation
- 2004-10-08 CN CNA2008100958532A patent/CN101294173A/en active Pending
- 2004-10-08 RU RU2006117769/04A patent/RU2357956C2/en not_active IP Right Cessation
- 2004-10-08 NZ NZ546744A patent/NZ546744A/en unknown
- 2004-10-08 MX MXPA06004084A patent/MXPA06004084A/en active IP Right Grant
- 2004-10-08 CA CA002543003A patent/CA2543003A1/en not_active Abandoned
- 2004-10-08 ME MEP-331/08A patent/MEP33108A/en unknown
- 2004-10-08 EP EP07007021A patent/EP1873146B1/en not_active Expired - Lifetime
- 2004-10-08 BR BRPI0415529-7A patent/BRPI0415529A/en not_active IP Right Cessation
- 2004-10-08 DK DK04765884T patent/DK1680405T3/en active
- 2004-10-08 AU AU2004287561A patent/AU2004287561B2/en not_active Expired - Fee Related
- 2004-10-08 SI SI200431054T patent/SI1680405T1/en unknown
- 2004-10-08 PT PT04765884T patent/PT1680405E/en unknown
- 2004-10-08 KR KR1020067007889A patent/KR20060120044A/en not_active Ceased
- 2004-10-08 CN CNB2004800306469A patent/CN100398520C/en not_active Expired - Fee Related
- 2004-10-08 JP JP2006535987A patent/JP4769190B2/en not_active Expired - Fee Related
- 2004-10-08 WO PCT/EP2004/011244 patent/WO2005044803A1/en not_active Ceased
- 2004-10-08 EP EP04765884A patent/EP1680405B1/en not_active Expired - Lifetime
- 2004-10-08 HR HR20090187T patent/HRP20090187T1/en unknown
- 2004-10-21 AR ARP040103818A patent/AR046553A1/en not_active Application Discontinuation
- 2004-10-22 UY UY28574A patent/UY28574A1/en unknown
-
2006
- 2006-03-16 ZA ZA200602231A patent/ZA200602231B/en unknown
- 2006-03-23 IL IL174524A patent/IL174524A/en not_active IP Right Cessation
- 2006-04-21 MA MA28955A patent/MA28213A1/en unknown
- 2006-05-12 NO NO20062149A patent/NO20062149L/en not_active Application Discontinuation
-
2009
- 2009-03-19 CL CL2009000674A patent/CL2009000674A1/en unknown
- 2009-03-23 CY CY20091100336T patent/CY1110458T1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |